Pollution from azithromycin-manufacturing promotes macrolide-resistance gene propagation and induces spatial and seasonal bacterial community shifts in receiving river sediments.

[1]  M. Z. Hashmi,et al.  Increased occurrence of heavy metals, antibiotics and resistance genes in surface soil after long-term application of manure. , 2018, The Science of the total environment.

[2]  D. Barceló,et al.  Transport of sediment borne contaminants in a Mediterranean river during a high flow event. , 2018, The Science of the total environment.

[3]  C. Garbisu,et al.  Treated and untreated wastewater effluents alter river sediment bacterial communities involved in nitrogen and sulphur cycling. , 2018, The Science of the total environment.

[4]  Zhanhui Qi,et al.  Diverse and abundant antibiotic resistance genes from mariculture sites of China's coastline. , 2018, The Science of the total environment.

[5]  M. He,et al.  Sub-inhibitory concentrations of heavy metals facilitate the horizontal transfer of plasmid-mediated antibiotic resistance genes in water environment. , 2018, Environmental pollution.

[6]  Hong Yang,et al.  Shift in the microbial community composition of surface water and sediment along an urban river. , 2018, The Science of the total environment.

[7]  N. Marathe,et al.  Antibiotics and common antibacterial biocides stimulate horizontal transfer of resistance at low concentrations. , 2018, The Science of the total environment.

[8]  A. Bielen,et al.  Functional Repertoire of Antibiotic Resistance Genes in Antibiotic Manufacturing Effluents and Receiving Freshwater Sediments , 2018, Front. Microbiol..

[9]  I. Senta,et al.  Negative environmental impacts of antibiotic-contaminated effluents from pharmaceutical industries. , 2017, Water research.

[10]  Bo Zhang,et al.  Structure and function of the microbial consortia of activated sludge in typical municipal wastewater treatment plants in winter , 2017, Scientific Reports.

[11]  L. Bleicher,et al.  Novel arsenic-transforming bacteria and the diversity of their arsenic-related genes and enzymes arising from arsenic-polluted freshwater sediment , 2017, Scientific Reports.

[12]  Gerard D. Wright,et al.  Lessons from the Environmental Antibiotic Resistome. , 2017, Annual review of microbiology.

[13]  Jer-Horng Wu,et al.  The novel mef(C)-mph(G) macrolide resistance genes are conveyed in the environment on various vectors. , 2017, Journal of global antimicrobial resistance.

[14]  Shashidhar,et al.  Occurrence of High Levels of Fluoroquinolones in Aquatic Environment due to Effluent Discharges from Bulk Drug Manufacturers , 2017 .

[15]  K. Harada,et al.  Water metagenomic analysis reveals low bacterial diversity and the presence of antimicrobial residues and resistance genes in a river containing wastewater from backyard aquacultures in the Mekong Delta, Vietnam. , 2017, Environmental pollution.

[16]  K. Brandt,et al.  Comparison of Metals and Tetracycline as Selective Agents for Development of Tetracycline Resistant Bacterial Communities in Agricultural Soil. , 2017, Environmental science & technology.

[17]  Tong Zhang,et al.  Co-occurrence of antibiotic and metal resistance genes revealed in complete genome collection , 2016, The ISME Journal.

[18]  Jincai Ma,et al.  Bacterial community composition and structure in an Urban River impacted by different pollutant sources. , 2016, The Science of the total environment.

[19]  J. Giesy,et al.  Using in situ bacterial communities to monitor contaminants in river sediments. , 2016, Environmental pollution.

[20]  R. Wattiez,et al.  Co-occurrence of integrase 1, antibiotic and heavy metal resistance genes in municipal wastewater treatment plants. , 2016, Water research.

[21]  Paul J. McMurdie,et al.  DADA2: High resolution sample inference from Illumina amplicon data , 2016, Nature Methods.

[22]  Andrea Di Cesare,et al.  Co-selection of antibiotic and heavy metal resistance in freshwater bacteria , 2016 .

[23]  M. Zielińska,et al.  Bacterial communities in full-scale wastewater treatment systems , 2016, World journal of microbiology & biotechnology.

[24]  Stinus Lindgreen,et al.  AdapterRemoval v2: rapid adapter trimming, identification, and read merging , 2016, BMC Research Notes.

[25]  Erik Kristiansson,et al.  Statistical evaluation of methods for identification of differentially abundant genes in comparative metagenomics , 2016, BMC Genomics.

[26]  M. Schloter,et al.  N2 Gas Flushing Alleviates the Loss of Bacterial Diversity and Inhibits Psychrotrophic Pseudomonas during the Cold Storage of Bovine Raw Milk , 2016, PloS one.

[27]  Erik Kristiansson,et al.  Co-occurrence of resistance genes to antibiotics, biocides and metals reveals novel insights into their co-selection potential , 2015, BMC Genomics.

[28]  E. Kristiansson,et al.  Isolation of novel IncA/C and IncN fluoroquinolone resistance plasmids from an antibiotic-polluted lake. , 2015, The Journal of antimicrobial chemotherapy.

[29]  E. Top,et al.  Plasmid Detection, Characterization, and Ecology , 2015, Microbiology spectrum.

[30]  S. Schuster,et al.  Draft Genome Sequence of Thauera sp. Strain SWB20, Isolated from a Singapore Wastewater Treatment Facility Using Gel Microdroplets , 2015, Genome Announcements.

[31]  J. Tiedje,et al.  Using the class 1 integron-integrase gene as a proxy for anthropogenic pollution , 2014, The ISME Journal.

[32]  D. G. Joakim Larsson,et al.  Pollution from drug manufacturing: review and perspectives , 2014, Philosophical Transactions of the Royal Society B: Biological Sciences.

[33]  W. Huber,et al.  Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2 , 2014, Genome Biology.

[34]  I. Ortiz,et al.  Pharmaceutical Industry Wastewater: Review of the Technologies for Water Treatment and Reuse , 2014 .

[35]  E. Kristiansson,et al.  Fluoroquinolones and qnr genes in sediment, water, soil, and human fecal flora in an environment polluted by manufacturing discharges. , 2014, Environmental science & technology.

[36]  Xin Zhao,et al.  Diversity change of microbial communities responding to zinc and arsenic pollution in a river of northeastern China , 2014, Journal of Zhejiang University-SCIENCE B.

[37]  Xiao-ming Lu,et al.  Characterization of Bacterial Communities in Sediments Receiving Various Wastewater Effluents with High-Throughput Sequencing Analysis , 2014, Microbial Ecology.

[38]  A. Pitondo-Silva,et al.  Aquatic environments polluted with antibiotics and heavy metals: a human health hazard , 2014, Environmental Science and Pollution Research.

[39]  N. Marathe,et al.  A Treatment Plant Receiving Waste Water from Multiple Bulk Drug Manufacturers Is a Reservoir for Highly Multi-Drug Resistant Integron-Bearing Bacteria , 2013, PloS one.

[40]  Siguo Liu,et al.  Complete sequence of the bla(NDM-1)-carrying plasmid pNDM-AB from Acinetobacter baumannii of food animal origin. , 2013, The Journal of antimicrobial chemotherapy.

[41]  C. Manaia,et al.  Urban wastewater treatment plants as hotspots for antibiotic resistant bacteria and genes spread into the environment: a review. , 2013, The Science of the total environment.

[42]  I. Senta,et al.  Occurrence and fate of dissolved and particulate antimicrobials in municipal wastewater treatment. , 2013, Water research.

[43]  T. Berendonk,et al.  Heavy metal driven co-selection of antibiotic resistance in soil and water bodies impacted by agriculture and aquaculture , 2012, Front. Microbio..

[44]  Pelin Yilmaz,et al.  The SILVA ribosomal RNA gene database project: improved data processing and web-based tools , 2012, Nucleic Acids Res..

[45]  G. Dantas,et al.  The Shared Antibiotic Resistome of Soil Bacteria and Human Pathogens , 2012, Science.

[46]  A. Klindworth,et al.  Evaluation of general 16S ribosomal RNA gene PCR primers for classical and next-generation sequencing-based diversity studies , 2012, Nucleic acids research.

[47]  Pienie Zwitserlood,et al.  Picture-Induced Semantic Interference Reflects Lexical Competition during Object Naming , 2012, Front. Psychology.

[48]  Tong Zhang,et al.  Plasmid Metagenome Reveals High Levels of Antibiotic Resistance Genes and Mobile Genetic Elements in Activated Sludge , 2011, PloS one.

[49]  X. Shi,et al.  Selection of Fecal Enterococci Exhibiting tcrB-Mediated Copper Resistance in Pigs Fed Diets Supplemented with Copper , 2011, Applied and Environmental Microbiology.

[50]  M. Schloter,et al.  Inter-laboratory evaluation of the ISO standard 11063 "Soil quality - Method to directly extract DNA from soil samples". , 2011, Journal of microbiological methods.

[51]  E. Kristiansson,et al.  Pyrosequencing of Antibiotic-Contaminated River Sediments Reveals High Levels of Resistance and Gene Transfer Elements , 2011, PloS one.

[52]  Charles W. Knapp,et al.  Antibiotic Resistance Gene Abundances Associated with Waste Discharges to the Almendares River near Havana, Cuba , 2010, Environmental science & technology.

[53]  M. Baclet,et al.  Quantitative multiplex real-time PCR for detecting class 1, 2 and 3 integrons. , 2010, Journal of Antimicrobial Chemotherapy.

[54]  Dong Li,et al.  Antibiotic Resistance Characteristics of Environmental Bacteria from an Oxytetracycline Production Wastewater Treatment Plant and the Receiving River , 2010, Applied and Environmental Microbiology.

[55]  M. Tysklind,et al.  Contamination of surface, ground, and drinking water from pharmaceutical production , 2009, Environmental Toxicology and Chemistry.

[56]  Marijan Ahel,et al.  Simultaneous Determination of Sulfonamides, Fluoroquinolones, Macrolides and Trimethoprim in Wastewater and River Water by LC-Tandem-MS , 2008 .

[57]  Min Yang,et al.  Determination and fate of oxytetracycline and related compounds in oxytetracycline production wastewater and the receiving river , 2008, Environmental toxicology and chemistry.

[58]  D. Larsson,et al.  Effluent from drug manufactures contains extremely high levels of pharmaceuticals. , 2007, Journal of hazardous materials.

[59]  F. Michel,et al.  Development and Application of Real-Time PCR Assays for Quantification of erm Genes Conferring Resistance to Macrolides-Lincosamides-Streptogramin B in Livestock Manure and Manure Management Systems , 2007, Applied and Environmental Microbiology.

[60]  D. Hughes,et al.  Sampling the Antibiotic Resistome , 2006, Science.

[61]  Satish C. Gupta,et al.  Antibacterial activity of soil-bound antibiotics. , 2005, Journal of environmental quality.

[62]  P. Nordmann,et al.  [Emergence of plasmid-mediated resistance to quinolones in Enterobacteriaceae]. , 2005, Pathologie-biologie.

[63]  D. Hoban,et al.  The use of macrolides in treatment of upper respiratory tract infections , 2005, Current allergy and asthma reports.

[64]  F. Martin-Laurent,et al.  Quantification of a novel group of nitrate-reducing bacteria in the environment by real-time PCR. , 2004, Journal of microbiological methods.

[65]  F. Aarestrup,et al.  tcrB, a Gene Conferring Transferable Copper Resistance in Enterococcus faecium: Occurrence, Transferability, and Linkage to Macrolide and Glycopeptide Resistance , 2002, Antimicrobial Agents and Chemotherapy.

[66]  D. Macdonald,et al.  Development and Evaluation of Consensus-Based Sediment Quality Guidelines for Freshwater Ecosystems , 2000, Archives of environmental contamination and toxicology.

[67]  C. Wentworth.  A Scale of Grade and Class Terms for Clastic Sediments , 1922, The Journal of Geology.

[68]  V. Ancona,et al.  Ecological effects of antibiotics on natural ecosystems: A review , 2018 .

[69]  Jian Xu,et al.  Effect of the selective pressure of sub-lethal level of heavy metals on the fate and distribution of ARGs in the catchment scale. , 2017, Environmental pollution.

[70]  Johan Bengtsson-Palme,et al.  Concentrations of antibiotics predicted to select for resistant bacteria: Proposed limits for environmental regulation. , 2016, Environment international.

[71]  T. Lumley,et al.  gplots: Various R Programming Tools for Plotting Data , 2015 .

[72]  Ž. Fiket,et al.  Sources, Distribution and Behavior of Major and Trace Elements in a Complex Karst Lake System , 2013, Aquatic Geochemistry.

[73]  T. Dougherty,et al.  7.18 – Macrolide Antibiotics , 2007 .

[74]  T. Pallasch.  Macrolide antibiotics. , 1997, Dentistry today.