Steatosis as a risk factor in liver surgery.

Objective: To review present knowledge of the influence of hepatic steatosis in liver surgery as derived from experimental and clinical studies. Summary Background Data: Hepatic steatosis is the most common chronic liver disease in the Western world, and it is associated with obesity, diabetes, and metabolic syndrome. Fatty accumulation affects hepatocyte homeostasis and potentially impairs recovery of steatotic livers after resection. This is reflected clinically in increased mortality and morbidity after liver resection in patients with any grade of steatosis. Because of the epidemic increase of obesity, hepatic steatosis will play an even more significant role in liver surgery.

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