论文信息 - 5-S-cysteinyldopa excretion after treatment with 8-methoxypsoralen and UVA light.

5-S-cysteinyldopa excretion after treatment with 8-methoxypsoralen and UVA light.

The excretion of the specific melanocytic metabolite 5-S-cysteinyldopa was studied in patients with psoriasis treated by 8-methoxypsoralen and UVA light. A pronounced increase was found after only 2 days treatment, although no increase in pigmentation could yet be observed. Peak values for urinary 5-S-cysteinyldopa were noted after 1 or 2 weeks treatment. Increase in pigmentation persisted after the excretion maxima for 5-S-cysteinyldopa.

[1] E. Rosengren,et al. 5-S-cysteinyldopa in the urine of melanoma patients. , 1977, Acta dermato-venereologica.

[2] H. Hönigsmann,et al. Photochemotherapy for psoriasis with orally administered methoxsalen. , 1976, Archives of dermatology.

[3] E. Rosengren,et al. Urinary excretion of 5-S-cysteinyldopa in patients with primary melanoma or melanoma metastasis. , 1975, Acta dermato-venereologica.

[4] E. Rosengren,et al. A sensitive method for determination of 5-S-cysteinyldopa. , 1973, Acta dermato-venereologica.