Polyamine supplementation reduces DNA damage in adipose stem cells cultured in 3-D
暂无分享,去创建一个
E. Mariani | F. Flamigni | S. Cetrullo | S. D’Adamo | S. Guidotti | R. Borzì | S. Santi | M. Minguzzi | G. Trisolino | G. Filardo | D. Platano | E. Assirelli | Stefania D’Adamo
[1] C. Scotchford,et al. Integrated Multi-Assay Culture Model for Stem Cell Chondrogenic Differentiation , 2019, International journal of molecular sciences.
[2] A. Tsezou,et al. The autophagic response to oxidative stress in osteoarthritic chondrocytes is deregulated , 2018, Free radical biology & medicine.
[3] K. Yoshikawa,et al. Opposite effect of polyamines on In vitro gene expression: Enhancement at low concentrations but inhibition at high concentrations , 2018, PloS one.
[4] F. Flamigni,et al. Emerging Players at the Intersection of Chondrocyte Loss of Maturational Arrest, Oxidative Stress, Senescence and Low-Grade Inflammation in Osteoarthritis , 2018, Oxidative medicine and cellular longevity.
[5] Guido Kroemer,et al. Spermidine in health and disease , 2018, Science.
[6] Yan Jin,et al. Autophagy controls mesenchymal stem cell properties and senescence during bone aging , 2017, Aging cell.
[7] N. Korolev,et al. Single-molecule compaction of megabase-long chromatin molecules by multivalent cations , 2017, Nucleic acids research.
[8] E. Mariani,et al. Glycogen Synthase Kinase-3β Inhibition Links Mitochondrial Dysfunction, Extracellular Matrix Remodelling and Terminal Differentiation in Chondrocytes , 2017, Scientific Reports.
[9] B. Kaang,et al. Phosphorylated CAV1 activates autophagy through an interaction with BECN1 under oxidative stress , 2017, Cell Death and Disease.
[10] Peng-Yuan Yang,et al. A comparative assessment of adipose‐derived stem cells from subcutaneous and visceral fat as a potential cell source for knee osteoarthritis treatment , 2017, Journal of cellular and molecular medicine.
[11] Xiaoxiang Zheng,et al. Induction of autophagy by spermidine is neuroprotective via inhibition of caspase 3-mediated Beclin 1 cleavage , 2017, Cell Death & Disease.
[12] M. Warr,et al. Autophagy maintains the metabolism and function of young and old (hematopoietic) stem cells , 2017, Nature.
[13] A. Mobasheri,et al. Adipose, Bone Marrow and Synovial Joint-Derived Mesenchymal Stem Cells for Cartilage Repair , 2016, Front. Genet..
[14] G. Fernandes,et al. Application of platelet-rich plasma with stem cells in bone and periodontal tissue engineering , 2016, Bone Research.
[15] Stephan J Sigrist,et al. Cardioprotection and lifespan extension by the natural polyamine spermidine , 2016, Nature Medicine.
[16] Claire Hoede,et al. Tissue-Specific Progenitor and Stem Cells Human Adipose-Derived Stem Cells Expanded Under Ambient Oxygen Concentration Accumulate Oxidative DNA Lesions and Experience Procarcinogenic DNA Replication Stress , 2017 .
[17] F. Flamigni,et al. Soft TCPTP Agonism—Novel Target to Rescue Airway Epithelial Integrity by Exogenous Spermidine , 2016, Front. Pharmacol..
[18] Y. Pers,et al. Adipose derived stem cells for regenerative therapy in osteoarticular diseases , 2016, Hormone molecular biology and clinical investigation.
[19] E. Mariani,et al. Lithium Chloride Dependent Glycogen Synthase Kinase 3 Inactivation Links Oxidative DNA Damage, Hypertrophy and Senescence in Human Articular Chondrocytes and Reproduces Chondrocyte Phenotype of Obese Osteoarthritis Patients , 2015, PloS one.
[20] A. Harris,et al. Autophagosome Proteins LC3A, LC3B and LC3C Have Distinct Subcellular Distribution Kinetics and Expression in Cancer Cell Lines , 2015, PloS one.
[21] D. H. Randle,et al. Drug Discovery Goes Three-Dimensional: Goodbye to Flat High-Throughput Screening? , 2015, Assay and drug development technologies.
[22] K. Marycz,et al. The Effect of Age on Osteogenic and Adipogenic Differentiation Potential of Human Adipose Derived Stromal Stem Cells (hASCs) and the Impact of Stress Factors in the Course of the Differentiation Process , 2015, Oxidative medicine and cellular longevity.
[23] C. Barbas,et al. Altered Metabolic and Stemness Capacity of Adipose Tissue-Derived Stem Cells from Obese Mouse and Human , 2015, PloS one.
[24] F. Rodier,et al. DDR-mediated crosstalk between DNA-damaged cells and their microenvironment , 2015, Front. Genet..
[25] K. von der Mark,et al. Chondrocytes Transdifferentiate into Osteoblasts in Endochondral Bone during Development, Postnatal Growth and Fracture Healing in Mice , 2014, PLoS genetics.
[26] R. Borzì,et al. Correction: Human Osteoarthritic Cartilage Shows Reduced In Vivo Expression of IL-4, a Chondroprotective Cytokine that Differentially Modulates IL-1β-Stimulated Production of Chemokines and Matrix-Degrading Enzymes In Vitro , 2014, PLoS ONE.
[27] R. Borzì,et al. Human Osteoarthritic Cartilage Shows Reduced In Vivo Expression of IL-4, a Chondroprotective Cytokine that Differentially Modulates IL-1β-Stimulated Production of Chemokines and Matrix-Degrading Enzymes In Vitro , 2014, PloS one.
[28] W. Richter,et al. Adipose-derived stromal cells for osteoarticular repair: trophic function versus stem cell activity , 2014, Expert Reviews in Molecular Medicine.
[29] F. Flamigni,et al. Polyamine delivery as a tool to modulate stem cell differentiation in skeletal tissue engineering , 2014, Amino Acids.
[30] D. Mccole,et al. Spermidine Stimulates T Cell Protein-tyrosine Phosphatase-mediated Protection of Intestinal Epithelial Barrier Function* , 2013, The Journal of Biological Chemistry.
[31] K. Koizumi,et al. Increased Polyamine Intake Inhibits Age-Associated Alteration in Global DNA Methylation and 1,2-Dimethylhydrazine-Induced Tumorigenesis , 2013, PloS one.
[32] F. Flamigni,et al. Enhanced osteoblastogenesis of adipose-derived stem cells on spermine delivery via β-catenin activation. , 2013, Stem cells and development.
[33] Jiying Chen,et al. Metabolic syndrome meets osteoarthritis , 2012, Nature Reviews Rheumatology.
[34] D. Karolina,et al. Circulating miRNA profiles in patients with metabolic syndrome. , 2012, The Journal of clinical endocrinology and metabolism.
[35] C. Redon,et al. γ-H2AX and other histone post-translational modifications in the clinic. , 2012, Biochimica et biophysica acta.
[36] G. Rogler,et al. The role for protein tyrosine phosphatase nonreceptor type 2 in regulating autophagosome formation , 2012, Annals of the New York Academy of Sciences.
[37] Julie V. Harness,et al. Recurrent variations in DNA methylation in human pluripotent stem cells and their differentiated derivatives. , 2012, Cell stem cell.
[38] F. Flamigni,et al. Role of polyamines in hypertrophy and terminal differentiation of osteoarthritic chondrocytes , 2012, Amino Acids.
[39] F. Tinahones,et al. Obesity short‐circuits stemness gene network in human adipose multipotent stem cells , 2011, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[40] C. Manferdini,et al. Evidence of specific characteristics and osteogenic potentiality in bone cells from tibia , 2011, Journal of cellular physiology.
[41] N. Kalupahana,et al. (n-3) Fatty acids alleviate adipose tissue inflammation and insulin resistance: mechanistic insights. , 2011, Advances in nutrition.
[42] A. Nakamura,et al. Recent developments in the use of γ -H2AX as a quantitative DNA double-strand break biomarker , 2011, Aging.
[43] B. Yankner,et al. The aging stress response. , 2010, Molecular cell.
[44] K. Soda. Polyamine intake, dietary pattern, and cardiovascular disease. , 2010, Medical hypotheses.
[45] Farshid Guilak,et al. Isolation of adipose-derived stem cells and their induction to a chondrogenic phenotype , 2010, Nature Protocols.
[46] P. Kohonen,et al. Inhibition of receptor tyrosine kinase signalling by small molecule agonist of T-cell protein tyrosine phosphatase , 2010, BMC Cancer.
[47] Frank Sinner,et al. Induction of autophagy by spermidine promotes longevity , 2009, Nature Cell Biology.
[48] Y. Dobashi,et al. Polyamine-rich food decreases age-associated pathology and mortality in aged mice , 2009, Experimental Gerontology.
[49] D. Klionsky,et al. Physiological functions of Atg6/Beclin 1: a unique autophagy-related protein , 2007, Cell Research.
[50] N. Mizushima,et al. How to Interpret LC3 Immunoblotting , 2007, Autophagy.
[51] M. Matsui,et al. LC3, an Autophagosome Marker, Can be Incorporated into Protein Aggregates Independent of Autophagy: Caution in the Interpretation of LC3 Localization , 2007, Autophagy.
[52] S. Jimenez,et al. Osteoarthritis cartilage histopathology: grading and staging. , 2006, Osteoarthritis and cartilage.
[53] V. Dulic,et al. DNA damage checkpoint kinase Chk2 triggers replicative senescence , 2004, The EMBO journal.
[54] Min Zhu,et al. Human adipose tissue is a source of multipotent stem cells. , 2002, Molecular biology of the cell.
[55] C. Caldarera,et al. Effect of polyamine depletion on caspase activation: a study with spermine synthase-deficient cells. , 2001, The Biochemical journal.
[56] S. Bettuzzi,et al. Manipulation of the expression of regulatory genes of polyamine metabolism results in specific alterations of the cell-cycle progression. , 2001, The Biochemical journal.
[57] M. Baggiolini,et al. Human chondrocytes express functional chemokine receptors and release matrix-degrading enzymes in response to C-X-C and C-C chemokines. , 2000, Arthritis and rheumatism.
[58] J. Zweier,et al. The natural polyamine spermine functions directly as a free radical scavenger. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[59] R. Casero,et al. Structural specificity of polyamines and polyamine analogues in the protection of DNA from strand breaks induced by reactive oxygen species. , 1998, Biochemical and biophysical research communications.
[60] Yong-Koo Park,et al. Grading and Staging , 2020, Tumors and Tumor-Like Lesions of Bone.
[61] Farshid Guilak,et al. Three-dimensional culture systems to induce chondrogenesis of adipose-derived stem cells. , 2011, Methods in molecular biology.
[62] K. Khanna,et al. ATM, a central controller of cellular responses to DNA damage , 2001, Cell Death and Differentiation.
[63] Mechanistic insights , 2022 .