Macrocycles containing bicyclophosphorane moieties [1]

The first stable macrocycles, 12–15, 16, 18, and 23, containing pentacovalent phosphorus have been obtained by an Atherton–Todd reaction between the bis(hydridobicyclophosphoranes) 3–7 and the corresponding binucleophile HO(CH2)2X(CH2)2OH. The tricyclic monophosphoranes 8–11 as well as the noncyclic derivative 20 have also been isolated. A pathway that accounts for the formation of all these compounds is proposed. The X-ray crystal study of two 16-membered rings, 14, 15, confirms the diequatorial placement of the macrocyclic frame on the trigonal bipyramidal phosphorus which retains the most favorable axial-equatorial-axial annelation of the bicyclic moiety. Comparison of these two molecular structures points out the effect of the nature of X on the conformation of the macrocycle.

[1]  Yande Huang,et al.  X‐Ray crystallographic study of a 1,3,2‐dioxaphosphorinane dimer containing five‐coordinated phosphorus in the 12‐membered ring , 1993 .

[2]  R. Wolf,et al.  Bicyclophosphoranes Containing Macrocycles , 1993 .

[3]  J. Dutasta,et al.  Structure and Properties of Mono-macrocyclic and Bis-macrocyclic Phosphorus-compounds (poster) , 1993 .

[4]  A. Caminade,et al.  Synthesis of main group elements containing macrocycles , 1993 .

[5]  V. Kalchenko,et al.  Phosphorus-Containing Macrocyclic “Host”-Molecules. Synthesis, Structure and Properties , 1993 .

[6]  M. Taieb,et al.  SYNTHESE, STRUCTURE ET REACTIVITE D'ORGANYLOXY BICYCLOPHOSPHORANES A LIAISON P[sbnd]H , 1992 .

[7]  J. Jaud,et al.  SYNTHÈSE DE DIOXAZAPHOSPHOCINES [Agrave] LIAISON PH. STRUCTURE CRISTALLINE ET MOLÉCULAIRE DU 4,4,8,8-TÉTRAMÉTHYL 6-TRIFLUOROACÉTYL 2-OXO PERHYDRO-1,3,6,2 σ4λ5 DIOXAZAPHOSPHOCINE , 1992 .

[8]  D. Houalla,et al.  On the extension of the atherton-todd reaction to the 1-organyloxy 1-hydridobicyclophosphoranes , 1992 .

[9]  R. O. Day,et al.  Pentacoordinated molecules. 92. Diequatorial and axial-equatorial orientations of eight-membered rings in monocyclic pentaoxyphosphoranes containing trifluoroethoxy groups , 1992 .

[10]  Ronald L. Bruening,et al.  Thermodynamic and kinetic data for macrocycle interactions with cations and anions , 1991 .

[11]  Gautam R. Desiraju,et al.  The C-H.cntdot..cntdot..cntdot.O hydrogen bond in crystals: what is it? , 1991 .

[12]  A. Caminade,et al.  Functionalized macrocycles incorporating phosphorus-nitrogen and phosphorus-oxygen bonds. Strategies of synthesis , 1991 .

[13]  Jaehoon Yu,et al.  Conformational properties of cyclic pentaalkoxy phosphoranes: Apical–equatorial attachment and nonchair conformation of the phosphorus‐containing six‐membered ring , 1991 .

[14]  L. Gorrichon,et al.  Étude conformationnelle et structurale de 1,5-diacétoxy-3,4-bis(bicyclophosphoranylato)quinate de méthyle , 1991 .

[15]  R. Wolf,et al.  Phosphoranylation de polyols: Voie d'accès aux phosphates d'intérêt biologique. I. Cas du myo-inositol , 1988 .

[16]  E. N. Tsvetkov,et al.  The Synthesis and Complex Forming Capacity of Phosphorus-containing Macrocycles , 1988 .

[17]  R. Wolf,et al.  Per - bicyclophosphoranylation d'alditols , 1985 .

[18]  D. B. Denney,et al.  Structures of some bicyclic and tricyclic phosphoranes in solution , 1980 .

[19]  W. Sheldrick 2,3,8,8-Tetraphenyl[1,3,2λ5]oxazaphospholino[2,3-b]benzo[d][1,3,2λ5]oxazaphospholine , 1976 .