Reduction of an eight-state mechanism of cotransport to a six-state model using a new computer program.

[1]  E. L. King,et al.  A Schematic Method of Deriving the Rate Laws for Enzyme-Catalyzed Reactions , 1956 .

[2]  D. Koshland,et al.  Comparison of experimental binding data and theoretical models in proteins containing subunits. , 1966, Biochemistry.

[3]  B. N. Goldstein,et al.  A new method for solving the problems of the stationary kinetics of enzymological reactions , 1966 .

[4]  R O Hurst A simplified approach to the use of determinants in the calculation of the rat equation for a complex enzyme system. , 1967, Canadian journal of biochemistry.

[5]  M Pring,et al.  The simulation and analysis by digital computer of biochemical systems in terms of kinetic models. 3. Generator programming. , 1967, Journal of theoretical biology.

[6]  M Pring,et al.  The simulation and analysis by digital computer of biochemical systems in terms of kinetic models. IV. Automatic derivation of enzymic rate laws. , 1968, Journal of theoretical biology.

[7]  S. Cha A simple method for derivation of rate equations for enzyme-catalyzed reactions under the rapid equilibrium assumption or combined assumptions of equilibrium and steady state. , 1968, The Journal of biological chemistry.

[8]  R O Hurst A computer program for writing the steady-state rate equation for a multisubstrate enzymic reaction. , 1969, Canadian journal of biochemistry.

[9]  S. Schultz,et al.  Coupled transport of sodium and organic solutes. , 1970, Physiological reviews.

[10]  P. Geck,et al.  Coupling in secondary active transport. Activation of transport by co-transport and-or counter-transport with the fluxes of other solutes. , 1972, Biochimica et biophysica acta.

[11]  J. Jacquez Models of lon and substrate cotransport and the effect of the membrane potential , 1972 .

[12]  I. H. Segel Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems , 1975 .

[13]  A. Cornish-Bowden,et al.  An automatic method for deriving steady-state rate equations. , 1977, The Biochemical journal.

[14]  R. Crane The gradient hypothesis and other models of carrier-mediated active transport. , 1977, Reviews of physiology, biochemistry and pharmacology.

[15]  Professor Dr. Alexander Levitzki Quantitative Aspects of Allosteric Mechanisms , 1978, Molecular Biology, Biochemistry and Biophysics.

[16]  H. Fromm Computer-assisted derivation of steady-state rate equations. , 1979, Methods in enzymology.

[17]  G. Kimmich,et al.  Evidence for an intestinal Na+:sugar transport coupling stoichiometry of 2.0. , 1980, Biochimica et biophysica acta.

[18]  U. Hopfer,et al.  The mechanism of Na+-dependent D-glucose transport. , 1980, The Journal of biological chemistry.

[19]  R. J. Turner,et al.  Kinetic analysis of a family of cotransport models. , 1981, Biochimica et biophysica acta.

[20]  E. Kempner,et al.  Radiation inactivation studies of the renal brush-border membrane phlorizin-binding protein. , 1982, The Journal of biological chemistry.

[21]  Turner Rj Quantitative studies of cotransport systems: Models and vesicles , 1983 .

[22]  B. Peerce,et al.  Sodium-induced conformational changes in the glucose transporter of intestinal brush borders. , 1984, The Journal of biological chemistry.

[23]  D G Herries The computerized derivation of steady-state rate equations for enzyme kinetics. , 1984, The Biochemical journal.

[24]  R. Crane,et al.  Studies of the kinetics of Na+ gradient-coupled glucose transport as found in brush-border membrane vesicles from rabbit jejunum. , 1984, Biochimica et biophysica acta.

[25]  G. Semenza,et al.  Biochemistry of the Na+, D-glucose cotransporter of the small-intestinal brush-border membrane. The state of the art in 1984. , 1984, Biochimica et biophysica acta.

[26]  G. Kimmich,et al.  Kinetic analysis of mechanism of intestinal Na+-dependent sugar transport. , 1985, The American journal of physiology.

[27]  B. Peerce,et al.  Evidence for tyrosyl residues at the Na+ site on the intestinal Na+/glucose cotransporter. , 1985, The Journal of biological chemistry.

[28]  P. Malathi,et al.  Radiation inactivation studies on the rabbit kidney sodium-dependent glucose transporter. , 1985, The Journal of biological chemistry.

[29]  J. Venter,et al.  The Small‐Intestinal Sodium‐Glucose Cotransporter(s) a , 1985, Annals of the New York Academy of Sciences.

[30]  B. Peerce,et al.  Distance between substrate sites on the Na-glucose cotransporter by fluorescence energy transfer. , 1986, Proceedings of the National Academy of Sciences of the United States of America.

[31]  H. Hikita,et al.  The computerized derivation of rate equations for enzyme reactions on the basis of the pseudo-steady-state assumption and the rapid-equilibrium assumption. , 1988, The Biochemical journal.

[32]  Stephen Wolfram,et al.  Mathematica: a system for doing mathematics by computer (2nd ed.) , 1991 .

[33]  G. Kimmich,et al.  Na+-coupled sugar transport: membrane potential-dependent Km and Ki for Na+. , 1988, The American journal of physiology.

[34]  R. Béliveau,et al.  Radiation-inactivation studies on brush-border-membrane vesicles. General considerations, and application to the glucose and phosphate carriers. , 1988, Biochemical Journal.

[35]  A. Moran,et al.  High affinity phlorizin binding to the LLC-PK1 cells exhibits a sodium:phlorizin stoichiometry of 2:1. , 1988, The Journal of biological chemistry.

[36]  D. Diedrich,et al.  Computer analysis reveals changes in renal Na+-glucose cotransporter in diabetic rats. , 1989, The American journal of physiology.

[37]  J. Kinsella,et al.  Transient state kinetic evidence for an oligomer in the mechanism of Na+-H+ exchange. , 1989, Proceedings of the National Academy of Sciences of the United States of America.

[38]  Ugolev Am,et al.  Two-channel transporter versus a single-channel Na+-dependent transporter for glucose and amino acids in rat and turtle. , 1990 .

[39]  E. Wright,et al.  Intestinal brush border membrane Na+/glucose cotransporter functions in situ as a homotetramer. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[40]  C. Smith-Maxwell,et al.  Whole cell recording of sugar-induced currents in LLC-PK1 cells. , 1990, The American journal of physiology.

[41]  J. M. Salhany Band 3 quaternary states and allosteric control of function , 1992 .

[42]  J. Kinsella,et al.  Proton dependence of the partial reactions of the sodium-proton exchanger in renal brush border membranes. , 1992, The Journal of biological chemistry.

[43]  D. Loo,et al.  Relaxation kinetics of the Na+/glucose cotransporter. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[44]  E. Wright,et al.  The intestinal Na+/glucose cotransporter. , 1993, Annual review of physiology.

[45]  J. Poirée,et al.  Oligomeric structure of the sodium-dependent phlorizin binding protein from kidney brush-border membranes. , 1993, Biochimica et biophysica acta.

[46]  M. Hediger,et al.  The high affinity Na+/glucose cotransporter. Re-evaluation of function and distribution of expression. , 1994, The Journal of biological chemistry.

[47]  F. Jackson,et al.  Thermodynamic determination of the Na+: glucose coupling ratio for the human SGLT1 cotransporter. , 1995, Biophysical journal.

[48]  S. L. Mayo,et al.  A multi-substrate single-file model for ion-coupled transporters. , 1996, Biophysical journal.

[49]  A. Berteloot,et al.  Sugar Transport Heterogeneity in the Kidney: Two Independent Transporters or Different Transport Modes through an Oligomeric Protein? 1. Glucose Transport Studies , 1996, The Journal of Membrane Biology.

[50]  G. Kimmich,et al.  The molecular mechanism and potential dependence of the Na+/glucose cotransporter. , 1996, Biophysical journal.

[51]  D. Loo,et al.  Presteady-State Currents of the Rabbit Na+/Glucose Cotransporter (SGLT1) , 1997, The Journal of Membrane Biology.