IκBα gene therapy in tumor necrosis factor-α- and chemotherapy-mediated apoptosis of hepatocellular carcinomas

[1]  M. Konopleva,et al.  Apoptosis. Molecules and mechanisms. , 1999, Advances in experimental medicine and biology.

[2]  Marty W. Mayo,et al.  NF-κB Induces Expression of the Bcl-2 Homologue A1/Bfl-1 To Preferentially Suppress Chemotherapy-Induced Apoptosis , 1999, Molecular and Cellular Biology.

[3]  Inder M. Verma,et al.  Severe Liver Degeneration in Mice Lacking the IκB Kinase 2 Gene , 1999 .

[4]  J. Cusack,et al.  Control of inducible chemoresistance: Enhanced anti-tumor therapy through increased apoptosis by inhibition of NF-κB , 1999, Nature Medicine.

[5]  L. Owen-Schaub,et al.  Activation-Dependent Transcriptional Regulation of the Human fas Promoter Requires NF-κB p50-p65 Recruitment , 1999, Molecular and Cellular Biology.

[6]  D. Green,et al.  Regulation of Fas-Ligand Expression during Activation-induced Cell Death in T Lymphocytes via Nuclear Factor κB* , 1999, The Journal of Biological Chemistry.

[7]  Mi-Ock Lee,et al.  Apoptosis in human hepatoma cell lines by chemotherapeutic drugs via fas‐dependent and fas‐independent pathways , 1999, Hepatology.

[8]  S. Ju,et al.  Identification of two NF-kappa B sites in mouse CD95 ligand (Fas ligand) promoter: functional analysis in T cell hybridoma. , 1998, Journal of immunology.

[9]  C. Y. Wang,et al.  NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation. , 1998, Science.

[10]  V. Dixit,et al.  Death receptors: signaling and modulation. , 1998, Science.

[11]  Christian Stehlik,et al.  Nuclear Factor (NF)-κB–regulated X-chromosome–linked iap Gene Expression Protects Endothelial Cells from Tumor Necrosis Factor α–induced Apoptosis , 1998, The Journal of experimental medicine.

[12]  D. Ferrari,et al.  Apoptosis signaling by death receptors. , 1998, European journal of biochemistry.

[13]  I. Herr,et al.  Inhibition of Nuclear Factor κB Activation Attenuates Apoptosis Resistance in Lymphoid Cells , 1998 .

[14]  D. Green,et al.  DNA damaging agents induce expression of Fas ligand and subsequent apoptosis in T lymphocytes via the activation of NF-kappa B and AP-1. , 1998, Molecular cell.

[15]  M. Malim,et al.  Suppression of tumor necrosis factor-induced cell death by inhibitor of apoptosis c-IAP2 is under NF-kappaB control. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[16]  K. Kimura,et al.  Structure of the promoter for the rat Fas antigen gene. , 1997, Biochimica et biophysica acta.

[17]  P. Galle,et al.  Drug-induced apoptosis in hepatoma cells is mediated by the CD95 (APO-1/Fas) receptor/ligand system and involves activation of wild-type p53. , 1997, The Journal of clinical investigation.

[18]  B. Williams,et al.  Deficient cytokine signaling in mouse embryo fibroblasts with a targeted deletion in the PKR gene: role of IRF‐1 and NF‐κB , 1997, The EMBO journal.

[19]  Seamus J. Martin,et al.  Suppression of TNF-α-Induced Apoptosis by NF-κB , 1996, Science.

[20]  H Schipper,et al.  Shifting the cancer paradigm: must we kill to cure? , 1995, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[21]  T. Maniatis,et al.  NF-κB: A lesson in family values , 1995, Cell.

[22]  D. Fisher.  Apoptosis in cancer therapy: Crossing the threshold , 1994, Cell.

[23]  T. Taniguchi,et al.  Cellular commitment to oncogene-induced transformation or apoptosis is dependent on the transcription factor IRF-1 , 1994, Cell.

[24]  J. Mudgett,et al.  The structure and complete nucleotide sequence of the murine gene encoding interleukin-1 beta converting enzyme (ICE). , 1994, Genomics.

[25]  L. Tartaglia,et al.  A novel domain within the 55 kd TNF receptor signals cell death , 1993, Cell.

[26]  S. Nagata,et al.  A novel protein domain required for apoptosis. Mutational analysis of human Fas antigen. , 1993, The Journal of biological chemistry.

[27]  I Nicoletti,et al.  A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. , 1991, Journal of immunological methods.

[28]  Z. Ao,et al.  IEX-1L, an apoptosis inhibitor involved in NF-kappaB-mediated cell survival. , 1998, Science.

[29]  D. Brenner,et al.  Prevents Apoptosis and Liver Dysfunction during Liver Regeneration , 1998 .

[30]  C. Y. Wang,et al.  TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB. , 1996, Science.

[31]  D. Baltimore,et al.  Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-kappa B. , 1995, Nature.

[32]  T. Maniatis,et al.  NF-kappa B: a lesson in family values. , 1995, Cell.

[33]  L. Liu,et al.  Intercalative antitumor drugs interfere with the breakage-reunion reaction of mammalian DNA topoisomerase II. , 1984, The Journal of biological chemistry.