Rapid tumor formation and development of neutrophilia and splenomegaly in nude mice transplanted with human cells expressing human T cell leukemia virus type I or Tax1

[1]  L. Ratner,et al.  Cytokine expression and tumorigenicity of large granular lymphocytic leukemia cells from mice transgenic for the tax gene of human T-cell leukemia virus type I. , 1997, Blood.

[2]  K. Shimotohno,et al.  Characterization of peripheral blood T-lymphocytes transduced with HTLV-I Tax mutants with different trans-activating phenotypes , 1997, Oncogene.

[3]  H. Ikeda,et al.  HTLV-I pX transgenic rats: development of cytokine-producing mammary carcinomas and establishment of the pX mammary carcinoma cell lines. , 1997, Leukemia.

[4]  J. Green,et al.  Abnormal B-cell function in HTLV-I-tax transgenic mice. , 1995, Oncogene.

[5]  T. Ley,et al.  Development of leukemia in mice transgenic for the tax gene of human T-cell leukemia virus type I. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[6]  G. Bergey,et al.  Extracellular human T‐cell lymphotropic virus type I tax protein induces cytokine production in adult human microglial cells , 1994, Annals of neurology.

[7]  M. F. Shannon,et al.  HTLV-1 tax activation of the GM-CSF and G-CSF promoters requires the interaction of NF-kB with other transcription factor families. , 1993, Oncogene.

[8]  Y. Tanaka,et al.  Functional conservation of the neutralizing domains on the external envelope glycoprotein of cosmopolitan and melanesian strains of human T cell leukemia/lymphoma virus type I. , 1993, The Journal of infectious diseases.

[9]  T. Tanaka,et al.  A model of in vivo cell proliferation of adult T-cell leukemia. , 1993, Blood.

[10]  W. Wachsman,et al.  Establishment of human T-cell leukemia virus type I T-cell lymphomas in severe combined immunodeficient mice. , 1993, Blood.

[11]  M. Yoshida HTLV-1 Tax: regulation of gene expression and disease. , 1993, Trends in microbiology.

[12]  R. Gallo,et al.  Complete nucleotide sequence of a highly divergent human T-cell leukemia (lymphotropic) virus type I (HTLV-I) variant from melanesia: genetic and phylogenetic relationship to HTLV-I strains from other geographical regions , 1993, Journal of virology.

[13]  N. Mori,et al.  [Detection of granulocyte-macrophage colony-stimulating factor activity in the supernatant of the cultured leukemic cells of adult T-cell leukemia with eosinophilia]. , 1993, [Rinsho ketsueki] The Japanese journal of clinical hematology.

[14]  M. Siekevitz,et al.  Transactivation of the c-myc promoter by human T cell leukemia virus type 1 tax is mediated by NF kappa B. , 1992, The Journal of biological chemistry.

[15]  W. Greene,et al.  A high proportion of early response genes are constitutively activated in T cells by HTLV-I. , 1992, Oncogene.

[16]  N. Mueller,et al.  Successful Graft of HTLV‐I‐transformed Human T‐Cells (MT‐2) in Severe Combined Immunodeficiency Mice Treated with Anti‐asialo GM‐1 Antibody , 1992, Japanese journal of cancer research : Gann.

[17]  J. Brady,et al.  Extracellular Tax1 protein stimulates tumor necrosis factor-beta and immunoglobulin kappa light chain expression in lymphoid cells , 1992, Journal of virology.

[18]  Akagi Tsuyoshi,et al.  Murine retroviral vectors expressing the tax1 gene of human T-cell leukemia virus type 1. , 1991 .

[19]  R. Lal,et al.  Constitutive production of interleukin-6 and tumor necrosis factor-alpha from spontaneously proliferating T cells in patients with human T-cell lymphotropic virus type-I/II. , 1991, Blood.

[20]  W. Blattner,et al.  Cytokine induction in HTLV‐I associated myelopathy and adult T‐cell leukemia: Alternate molecular mechanisms underlying retroviral pathogenesis , 1991, Journal of cellular biochemistry.

[21]  Yuetsu Tanaka,et al.  Production of a recombinant human T‐cell leukemia virus type‐I trans‐activator (tax1) antigen and its utilization for generation of monoclonal antibodies against various epitopes on the tax1 antigen , 1991, International journal of cancer.

[22]  N. Nomura,et al.  HTLV-1 Tax induces expression of various immediate early serum responsive genes. , 1991, Oncogene.

[23]  S. Hanada,et al.  Tumor necrosis factor-beta in the serum of adult T-cell leukemia with hypercalcemia. , 1991, Blood.

[24]  K. Shimotohno,et al.  Murine retroviral vectors expressing the tax1 gene of human T-cell leukemia virus type 1. , 1991, Gene.

[25]  H. Tsuda,et al.  Spontaneous production of interleukin 6 by adult T-cell leukaemia cells. , 1990, British Journal of Cancer.

[26]  J. Brady,et al.  Induction of nuclear NF-kappa B DNA binding activity after exposure of lymphoid cells to soluble tax1 protein. , 1990, The New biologist.

[27]  A. Ogata,et al.  Elevated levels of interleukin-6 in serum and cerebrospinal fluid of HTLV-I-associated myelopathy/tropical spastic paraparesis , 1990, Journal of the Neurological Sciences.

[28]  S. Yamaoka,et al.  Oncogenic transformation by the tax gene of human T-cell leukemia virus type I in vitro. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[29]  R. Pozzatti,et al.  The human T-lymphotropic virus type I tax gene can cooperate with the ras oncogene to induce neoplastic transformation of cells , 1990, Molecular and cellular biology.

[30]  T. Waldmann,et al.  trans activation of granulocyte-macrophage colony-stimulating factor and the interleukin-2 receptor in transgenic mice carrying the human T-lymphotropic virus type 1 tax gene , 1989, Molecular and cellular biology.

[31]  T. Sugimura,et al.  Detection of mRNA for the tax1/rex1 gene of human T-cell leukemia virus type I in fresh peripheral blood mononuclear cells of adult T-cell leukemia patients and viral carriers by using the polymerase chain reaction. , 1989, Proceedings of the National Academy of Sciences of the United States of America.

[32]  L. Ratner Regulation of expression of the c-sis proto-oncogene. , 1989, Nucleic acids research.

[33]  T. Uchiyama,et al.  Expression of Cytokine mRNA in Leukemic Cells from Adult T Cell Leukemia Patients , 1989, Japanese journal of cancer research : Gann.

[34]  H. Kondoh,et al.  Improved mammalian vectors for high expression of G418 resistance. , 1987, Cell structure and function.

[35]  R. K. Reynolds,et al.  The tat gene of human T-lymphotropic virus type 1 induces mesenchymal tumors in transgenic mice. , 1987, Science.

[36]  W. Greene,et al.  Interleukin 1 gene expression in adult T cell leukemia. , 1987, The Journal of clinical investigation.

[37]  M. Siekevitz,et al.  Activation of interleukin 2 and interleukin 2 receptor (Tac) promoter expression by the trans-activator (tat) gene product of human T-cell leukemia virus, type I. , 1987, Proceedings of the National Academy of Sciences of the United States of America.

[38]  T. Taniguchi,et al.  Induction of interleukin 2 receptor gene expression by p40x encoded by human T‐cell leukemia virus type 1. , 1986, The EMBO journal.

[39]  D. Slamon,et al.  Regulation of expression of human granulocyte/macrophage colony-stimulating factor. , 1986, Proceedings of the National Academy of Sciences of the United States of America.

[40]  J. Yodoi,et al.  Absolute neutrophilia in adult T cell leukemia. , 1986, Japanese journal of cancer research : Gann.

[41]  F. Barin,et al.  ANTIBODIES TO HUMAN T-LYMPHOTROPIC VIRUS TYPE-I IN PATIENTS WITH TROPICAL SPASTIC PARAPARESIS , 1985, The Lancet.

[42]  J. Sodroski,et al.  A transcriptional activator protein encoded by the x-lor region of the human T-cell leukemia virus. , 1985, Science.

[43]  Donald Metcalf,et al.  Identification of the human analogue of a regulator that induces differentiation in murine leukaemic cells , 1985, Nature.

[44]  R. Weiss,et al.  Productive infection and cell-free transmission of human T-cell leukemia virus in a nonlymphoid cell line. , 1983, Science.

[45]  T. Sugimura,et al.  Establishment and characterization of 10 cell lines derived from patients with adult T-cell leukemia. , 1983, Proceedings of the National Academy of Sciences of the United States of America.

[46]  K. Sugamura,et al.  Establishment of human cell lines constitutively producing immune interferon: transformation of normal T cells by a human retrovirus. , 1983, Journal of immunology.

[47]  Robert A. Weinberg,et al.  Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes , 1983, Nature.

[48]  M. Yoshida,et al.  Human adult T-cell leukemia virus: complete nucleotide sequence of the provirus genome integrated in leukemia cell DNA. , 1983, Proceedings of the National Academy of Sciences of the United States of America.

[49]  M. Kannagi,et al.  Transformation of human leukocytes by cocultivation with an adult T cell leukemia virus producer cell line. , 1982, Science.

[50]  N. Kamada,et al.  A retrovirus associated with human adult T-cell leukemia: in vitro activation. , 1982, Gan.

[51]  Y. Ohtsuki,et al.  Type C virus particles in a cord T-cell line derived by co-cultivating normal human cord leukocytes and human leukaemic T cells , 1981, Nature.

[52]  John D. Minna,et al.  Detection and isolation of type C retrovirus particles from fresh and cultured lymphocytes of a patient with cutaneous T-cell lymphoma , 1980, Proceedings of the National Academy of Sciences.

[53]  E. Canaani,et al.  Nucleotide sequence analysis of the transforming region and large terminal redundancies of Moloney murine sarcoma virus. , 1980, Proceedings of the National Academy of Sciences of the United States of America.

[54]  J. Rhim,et al.  The relationship between tumorigenicity, growth in agar and fibrinolytic activity in a line of human osteosarcoma cells , 1975, International journal of cancer.

[55]  B. Wahrén,et al.  [Leukemia virus]. , 1966, Tidskrift for Sveriges sjukskoterskor.

[56]  I. Verma,et al.  c-fos promoter transactivation by the tax , protein of human T-cell leukemia virus type I ( transcription / regulatory elements / oncogenesis ) , 2022 .