Emerging Role of Aurora A in Radioresistance: A Comprehensive Review
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[1] Anna Cha,et al. Cyclin-dependent Kinase 1 and Aurora Kinase choreograph mitotic storage and redistribution of a growth factor receptor , 2021, PLoS biology.
[2] Arnoud Boot,et al. Multiomic analysis and immunoprofiling reveal distinct subtypes of human angiosarcoma. , 2020, The Journal of clinical investigation.
[3] P. Setny. Conserved internal hydration motifs in protein kinases , 2020, Proteins.
[4] James B. Mitchell,et al. Radiation-induced Adaptive Response: New Potential for Cancer Treatment , 2020, Clinical Cancer Research.
[5] M. Kavallaris,et al. Interplay between MycN and c-Myc regulates radioresistance and cancer stem cell phenotype in neuroblastoma upon glutamine deprivation , 2020, Theranostics.
[6] J. Chen,et al. Long Noncoding RNA MALAT1 Contributes to Sorafenib Resistance by Targeting miR-140-5p/Aurora-A Signaling in Hepatocellular Carcinoma , 2020, Molecular Cancer Therapeutics.
[7] Long-Bang Chen,et al. Aurora-a confers radioresistance in human hepatocellular carcinoma by activating NF-κB signaling pathway , 2019, BMC Cancer.
[8] R. Hoffman,et al. Aurora-A/NF-ĸB Signaling Is Associated With Radio-resistance in Human Lung Adenocarcinoma , 2019, AntiCancer Research.
[9] Ping Wang,et al. Inhibition of Aurora A enhances radiosensitivity in selected lung cancer cell lines , 2019, Respiratory Research.
[10] M. Dutreix,et al. Altering DNA Repair to Improve Radiation Therapy: Specific and Multiple Pathway Targeting , 2019, Front. Oncol..
[11] Y. Hosokawa,et al. Understanding the mechanism underlying the acquisition of radioresistance in human prostate cancer cells. , 2019, Oncology letters.
[12] L. Magnaghi-Jaulin,et al. Aurora A Protein Kinase: To the Centrosome and Beyond , 2019, Biomolecules.
[13] M. de Ridder,et al. Hypoxic Radioresistance: Can ROS Be the Key to Overcome It? , 2019, Cancers.
[14] Yan Chen,et al. LncRNA TUG1 promotes cells proliferation and inhibits cells apoptosis through regulating AURKA in epithelial ovarian cancer cells , 2018, Medicine.
[15] Hyuk Cho,et al. Differential Selective Pressures Experienced by the Aurora Kinase Gene Family , 2017, International journal of molecular sciences.
[16] R. Bronson,et al. Cell cycle-targeting microRNAs promote differentiation by enforcing cell-cycle exit , 2017, Proceedings of the National Academy of Sciences.
[17] T. Cech,et al. How do lncRNAs regulate transcription? , 2017, Science Advances.
[18] Yu-Chieh Su,et al. Targeting the PI3K/AKT/mTOR signaling pathway as an effectively radiosensitizing strategy for treating human oral squamous cell carcinoma in vitro and in vivo , 2017, Oncotarget.
[19] Guangyuan Song,et al. AURKA promotes cancer metastasis by regulating epithelial-mesenchymal transition and cancer stem cell properties in hepatocellular carcinoma. , 2017, Biochemical and biophysical research communications.
[20] Wenbo Li,et al. Down-regulation of LncRNA TUG1 enhances radiosensitivity in bladder cancer via suppressing HMGB1 expression , 2017, Radiation oncology.
[21] K. Shah,et al. The Aurora-A–Twist1 axis promotes highly aggressive phenotypes in pancreatic carcinoma , 2017, Journal of Cell Science.
[22] Ruozheng Wang,et al. Aurora-A affects radiosenstivity in cervical squamous cell carcinoma and predicts poor prognosis , 2017, Oncotarget.
[23] Masaru Ishii,et al. Cell-cycle-controlled radiation therapy was effective for treating a murine malignant melanoma cell line in vitro and in vivo , 2016, Scientific Reports.
[24] E. Sajo,et al. The radiosensitizing effect of the aurora kinase inhibitors, ENMD-2076, on canine mast cell tumours in vitro. , 2016, Veterinary and comparative oncology.
[25] B. Haffty,et al. The relevance of molecular biomarkers in cervical cancer patients treated with radiotherapy. , 2015, Annals of translational medicine.
[26] A. Musacchio,et al. The Aurora B Kinase in Chromosome Bi-Orientation and Spindle Checkpoint Signaling , 2015, Front. Oncol..
[27] K. Schindler,et al. Functions of Aurora kinase C in meiosis and cancer , 2015, Front. Cell Dev. Biol..
[28] J. Seong,et al. Daurinol Enhances the Efficacy of Radiotherapy in Lung Cancer via Suppression of Aurora Kinase A/B Expression , 2015, Molecular Cancer Therapeutics.
[29] B. Neumann,et al. The Aurora-A inhibitor MLN8237 affects multiple mitotic processes and induces dose-dependent mitotic abnormalities and aneuploidy , 2014, Oncotarget.
[30] Gong Yang,et al. Corrigendum to “Aurora-A controls cancer cell radio- and chemoresistance via ATM/Chk2-mediated DNA repair networks” [Biochim. Biophys. Acta 1843 (2014) 934–944] , 2014 .
[31] D. Chung,et al. Targeting aurora kinase A inhibits hypoxia-mediated neuroblastoma cell tumorigenesis. , 2014, Anticancer research.
[32] Gong Yang,et al. Aurora-A controls cancer cell radio- and chemoresistance via ATM/Chk2-mediated DNA repair networks. , 2014, Biochimica et biophysica acta.
[33] J. Crispino,et al. The Aurora Kinases in Cell Cycle and Leukemia , 2014, Oncogene.
[34] B. Teh,et al. A novel panel of biomarkers predicts radioresistance in patients with squamous cell carcinoma of the head and neck. , 2014, European journal of cancer.
[35] U. Mayor,et al. Ubiquitination site preferences in anaphase promoting complex/cyclosome (APC/C) substrates , 2013, Open Biology.
[36] W. De,et al. The role of Aurora A in hypoxia-inducible factor 1α-promoting malignant phenotypes of hepatocelluar carcinoma , 2013, Cell cycle.
[37] R. Bayliss,et al. Insights into Aurora-A Kinase Activation Using Unnatural Amino Acids Incorporated by Chemical Modification , 2013, ACS chemical biology.
[38] T. Kundu,et al. Surface enhanced Raman spectroscopy of Aurora kinases: direct, ultrasensitive detection of autophosphorylation , 2013 .
[39] L. Moretti,et al. MLN8054, a small molecule inhibitor of aurora kinase a, sensitizes androgen-resistant prostate cancer to radiation. , 2011, International journal of radiation oncology, biology, physics.
[40] K. Pollok,et al. Preclinical activity of a novel multiple tyrosine kinase and aurora kinase inhibitor, ENMD‐2076, against multiple myeloma , 2010, British journal of haematology.
[41] B. Lim,et al. Aurora-A Contributes to Radioresistance by Increasing NF-&kgr;B DNA Binding , 2010, Radiation research.
[42] D. Lane,et al. Discovery of N-phenyl-4-(thiazol-5-yl)pyrimidin-2-amine aurora kinase inhibitors. , 2010, Journal of medicinal chemistry.
[43] L. Pustilnik,et al. PF-03814735, an Orally Bioavailable Small Molecule Aurora Kinase Inhibitor for Cancer Therapy , 2010, Molecular Cancer Therapeutics.
[44] R. Fucini,et al. SNS-314, a pan-Aurora kinase inhibitor, shows potent anti-tumor activity and dosing flexibility in vivo , 2010, Cancer Chemotherapy and Pharmacology.
[45] Jeffrey Ecsedy,et al. A novel Aurora-A kinase inhibitor MLN8237 induces cytotoxicity and cell-cycle arrest in multiple myeloma. , 2009, Blood.
[46] A. Wynshaw-Boris,et al. An essential role of the aPKC–Aurora A–NDEL1 pathway in neurite elongation by modulation of microtubule dynamics , 2009, Nature Cell Biology.
[47] Y. Toiyama,et al. Correlation of CD133, OCT4, and SOX2 in Rectal Cancer and Their Association with Distant Recurrence After Chemoradiotherapy , 2009, Annals of Surgical Oncology.
[48] Mladen Vinković,et al. Fragment-based discovery of the pyrazol-4-yl urea (AT9283), a multitargeted kinase inhibitor with potent aurora kinase activity. , 2009, Journal of medicinal chemistry.
[49] A. Dar,et al. The Aurora kinase A Regulates GSK-3β in Gastric Cancer Cells , 2008, Oncogene.
[50] S. Dimitrov,et al. Localization of Aurora A and Aurora B kinases during interphase: Role of the N-Terminal domain , 2008, Cell cycle.
[51] Paola Storici,et al. PHA-739358, a potent inhibitor of Aurora kinases with a selective target inhibition profile relevant to cancer , 2007, Molecular Cancer Therapeutics.
[52] J. Bourhis,et al. Enhancement of radiation response by inhibition of Aurora-A kinase using siRNA or a selective Aurora kinase inhibitor PHA680632 in p53-deficient cancer cells , 2007, British Journal of Cancer.
[53] Wenlin Huang,et al. Aurora-A, a negative prognostic marker, increases migration and decreases radiosensitivity in cancer cells. , 2007, Cancer research.
[54] F. Gergely,et al. Aurora-A: the maker and breaker of spindle poles , 2007, Journal of Cell Science.
[55] Wei Chen,et al. Antitumor activity of MLN8054, an orally active small-molecule inhibitor of Aurora A kinase , 2007, Proceedings of the National Academy of Sciences.
[56] Q. Zhan,et al. Overexpression of Aurora-A kinase promotes tumor cell proliferation and inhibits apoptosis in esophageal squamous cell carcinoma cell line , 2006, Cell Research.
[57] A. Puisieux,et al. A twist for survival and cancer progression , 2005, British Journal of Cancer.
[58] L. Lim,et al. The GIT-associated kinase PAK targets to the centrosome and regulates Aurora-A. , 2005, Molecular cell.
[59] Philippe Sanseau,et al. Evolutionary relationships of Aurora kinases: Implications for model organism studies and the development of anti-cancer drugs , 2004, BMC Evolutionary Biology.
[60] R. Knegtel,et al. Crystal Structure of Aurora-2, an Oncogenic Serine/Threonine Kinase* , 2002, The Journal of Biological Chemistry.
[61] Jun Yang,et al. Cell-cycle-dependent Regulation of Human aurora A Transcription Is Mediated by Periodic Repression of E4TF1* , 2002, The Journal of Biological Chemistry.
[62] W. Earnshaw,et al. Chromosomal passengers and the (aurora) ABCs of mitosis. , 2001, Trends in cell biology.
[63] E. Lees,et al. The mitotic serine/threonine kinase Aurora2/AIK is regulated by phosphorylation and degradation , 2000, Oncogene.
[64] R. Brown,et al. Cell cycle arrests and radiosensitivity of human tumor cell lines: dependence on wild-type p53 for radiosensitivity. , 1994, Cancer research.
[65] M. Mapelli,et al. The Aurora-A/TPX2 Axis Directs Spindle Orientation by Regulating NuMa and Microtubule Dynamics , 2020, Social Science Research Network.
[66] Ruozheng Wang,et al. Mechanism of cervical squamous cell carcinoma radioresistance conferred by Aurora-A , 2017 .
[67] Sun Hui-zhe. Mechanistic study of pancreatic cancer cell radioresistance conferred by Aurora-A , 2013 .
[68] V. Markovtsov,et al. Preclinical characterization of Aurora kinase inhibitor R763/AS703569 identified through an image-based phenotypic screen , 2009, Journal of Cancer Research and Clinical Oncology.
[69] Chi-Ying F. Huang,et al. Gene expression profiles of the aurora family kinases. , 2006, Gene expression.
[70] J. Weitzman. Radiation resistance , 2001, Genome Biology.