Quantitative EEG alterations after isovolernic‐hemodilutional augmenhtion of cerebral perfhion in stroke patients

Eleven patients with ischemic neurologic deficits in the middle cerebral arterial (MCA) territory and ipsilateral slowing on initial EEG underwent venesection and equal volume replacement with intravenous 5% human serum albumin. As the mean hematocrit was reduced by 19%, the mean cerebral blood flow (CBF) in the MCA territory of the affected and contralateral hemisphere determined by the 133Xenon inhalation technique increased 18 and 21%, respectively. Similarly, CBF in the contralateral occipital region increased 17%. The percentage total slow-wave EEG activity (fractional sum of theta and delta activity, 1.0 to 7.5 Hz) determined by fourier analysis was reduced significantly in the affected MCA territory and in the contralateral occipital region within 1 to 2 hours after isovolemic hemodilution. Using quantitative EEG analysis, rapid improvement in background EEG activity can be demonstrated following the diffuse elevation in CBF by hemodilution.

[1]  G. Pfurtscheller,et al.  Frequency changes of sensorimotor EEG rhythm after revascularization surgery. , 1983, Electroencephalography and clinical neurophysiology.

[2]  J. Wood,et al.  Observations during hypervolemic hemodilution of patients with acute focal cerebral ischemia. , 1982, JAMA.

[3]  G Pfurtscheller,et al.  The influence of skull defects and reperfusion after extra-intracranial arterial bypass surgery on the sensorimotor EEG rhythm. , 1982, Journal of neurology, neurosurgery, and psychiatry.

[4]  R. Kron,et al.  Rheological aspects of experimental hypervolemic hemodilution with low molecular weight dextran: relationships of cortical blood flow, cardiac output, and intracranial pressure to fresh blood viscosity and plasma volume. , 1982, Neurosurgery.

[5]  E. Jonkman,et al.  Effect of the extra‐intracranial (STA‐MCA) arterial anastomosis on EEG and cerebral blood flow: a controlled study of patients with unilateral cerebral ischemia. , 1982, Stroke.

[6]  R. Rhodes,et al.  Improved neurologic function after cerebrovascular accident with extracranial-intracranial arterial bypass. , 1981, Surgery.

[7]  J. Marshall,et al.  EFFECT OF HAEMATOCRIT ON CAROTID STENOSIS AND CEREBRAL INFARCTION , 1981, The Lancet.

[8]  M. Kaste,et al.  Ethanol Intoxication: A Risk Factor for Ischemic Brain Infarctionin Adolescents and Young Adults , 1981, Stroke.

[9]  I A Sulg,et al.  Comparison of quantitative EEG parameters from four different analysis techniques in evaluation of relationships between EEG and CBF in brain infarction. , 1981, Electroencephalography and clinical neurophysiology.

[10]  B. Neundörfer,et al.  The prognostic value of EEG in ischaemic cerebral insults. , 1980, Electroencephalography and clinical neurophysiology.

[11]  H. Tohgi,et al.  Importance of the Hematocrit as a Risk Factor in Cerebral Infarction , 1978, Stroke.

[12]  B. Cohen,et al.  Quantification of computer analyzed serial EEGs from stroke patients. , 1976, Electroencephalography and clinical neurophysiology.

[13]  E. Melamed,et al.  Correlation between regional cerebral blood flow and EEG frequency in the contralateral hemisphere in acute cerebral infarction , 1975, Journal of the Neurological Sciences.

[14]  A. Aranibar,et al.  High Blood Viscosity Syndrome in Cerebral Infarction , 1974, Stroke.

[15]  N Veall,et al.  The Partition of Trace Amounts of Xenon Between Human Blood and Brain Tissues at 37?C , 1965 .

[16]  B. Harvald,et al.  The electroencephalogram in acute cerebrovascular lesions , 1964, Neurology.

[17]  E. Foltz,et al.  Serial Electroencephalography in Vascular Lesions of the Brain , 1952, Neurology.

[18]  F. Simeone,et al.  Failure of intravascular volume expansion without hemodilution to elevate cortical blood flow in region of experimental focal ischemia. , 1982, Journal of neurosurgery.

[19]  F. Sakai,et al.  Regional cerebral blood flow, diaschisis, and steal after stroke. , 1979, Neurological research.

[20]  P. E. Maspes,et al.  [Thrombosis of the internal carotid artery in the neck]. , 1952, Sistema nervoso.