A Review of Economic Factors Related to the Delivery of Health Care for Chronic Low Back Pain

We describe tools used to evaluate the economic impact of health care interventions, discuss the economic burden of chronic low back pain, and review evidence on the cost‐effectiveness of treating failed back surgery syndrome with spinal cord stimulation, intrathecal drug delivery, acupuncture, epidural injections, disc prosthesis, lumbar fusion, and noninvasive therapies. We also mention the lack of cost studies for emerging therapies, such as vibrotherapy and peripheral nerve field stimulation. Topics include types of cost studies; the economic perspectives taken by such studies; direct and indirect costs; measures of success; definitions of cost‐effectiveness, incremental cost‐effectiveness, incremental cost‐utility ratios, and quality‐adjusted life years; the concept of maximum willingness to pay; and the use of cost‐effectiveness models.

[1]  R. Taylor,et al.  Questions about Turner et al. Spinal cord stimulation for failed back surgery syndrome: Outcomes in a worker’s compensation setting , 2010, PAIN®.

[2]  Krishna Kumar,et al.  Treatment of chronic pain by using intrathecal drug therapy compared with conventional pain therapies: a cost-effectiveness analysis. , 2002, Journal of neurosurgery.

[3]  G. Duvel The study group. , 1980 .

[4]  G. Boriani,et al.  Cost-effectiveness of implantable cardioverter-defibrillators. , 2001, European heart journal.

[5]  Krishna Kumar,et al.  Cost Effectiveness of Intrathecal Drug Therapy in Management of Chronic Nonmalignant Pain , 2013, The Clinical journal of pain.

[6]  K. Strauch,et al.  Low Back Pain in Primary Care: Costs of Care and Prediction of Future Health Care Utilization , 2010, Spine.

[7]  Krishna Kumar,et al.  Complications of spinal cord stimulation, suggestions to improve outcome, and financial impact. , 2006, Journal of neurosurgery. Spine.

[8]  J. Anema,et al.  The Trend in Total Cost of Back Pain in the Netherlands in the Period 2002 to 2007 , 2011, Spine.

[9]  R. Taylor,et al.  Spinal cord stimulation for failed back surgery syndrome: A decision-analytic model and cost-effectiveness analysis , 2005, International Journal of Technology Assessment in Health Care.

[10]  T. Errico,et al.  Comparative Charge Analysis of One- and Two-Level Lumbar Total Disc Arthroplasty Versus Circumferential Lumbar Fusion , 2007, Spine.

[11]  G. Úrrutia,et al.  The efficacy, safety, effectiveness, and cost-effectiveness of ultrasound and shock wave therapies for low back pain: a systematic review. , 2011, The spine journal : official journal of the North American Spine Society.

[12]  V. Yakovleva,et al.  Peripheral Nerve Field Stimulation in the Treatment of Postlaminectomy Syndrome after Multilevel Spinal Surgeries , 2011, Neuromodulation : journal of the International Neuromodulation Society.

[13]  R. Lipton,et al.  Lost productive time and cost due to common pain conditions in the US workforce. , 2003, JAMA.

[14]  Ricardo Pietrobon,et al.  Estimates and Patterns of Direct Health Care Expenditures Among Individuals With Back Pain in the United States , 2004, Spine.

[15]  B. L. Bauer,et al.  Dorsal column stimulation (DCS): cost to benefit analysis. , 1991, Acta neurochirurgica. Supplementum.

[16]  M. Mychaskiw,et al.  NP1 INDIRECT COSTS DUE TO BACK PAIN IN THE UNITED STATES , 2001 .

[17]  R. Collins,et al.  Randomised controlled trial to compare surgical stabilisation of the lumbar spine with an intensive rehabilitation programme for patients with chronic low back pain: the MRC spine stabilisation trial , 2005, BMJ : British Medical Journal.

[18]  N. Arden,et al.  Cost-effectiveness and safety of epidural steroids in the management of sciatica. , 2005, Health technology assessment.

[19]  J. Katz,et al.  A Review of the 2001 Volvo Award Winner in Clinical Studies: Lumbar Fusion Versus Nonsurgical Treatment for Chronic Low Back Pain: A Multicenter Randomized Controlled Trial From the Swedish Lumbar Spine Study Group , 2006, Spine.

[20]  Krishna Kumar,et al.  Treatment of Chronic Pain with Spinal Cord Stimulation versus Alternative Therapies: Cost-effectiveness Analysis , 2002, Neurosurgery.

[21]  R. Deyo,et al.  Expenditures and health status among adults with back and neck problems. , 2008, JAMA.

[22]  A. Nordwall,et al.  Cost-Effectiveness of Lumbar Fusion and Nonsurgical Treatment for Chronic Low Back Pain in the Swedish Lumbar Spine Study: A Multicenter, Randomized, Controlled Trial From the Swedish Lumbar Spine Study Group , 2004, Spine.

[23]  R. North,et al.  Cost-effectiveness analysis of spinal cord stimulation in treatment of failed back surgery syndrome. , 1997, Journal of pain and symptom management.

[24]  B. Bataille,et al.  Back pain: a real target for spinal cord stimulation? , 2012, Neurosurgery.

[25]  D. Knol,et al.  Randomised controlled trial of integrated care to reduce disability from chronic low back pain in working and private life , 2010, BMJ : British Medical Journal.

[26]  E. Buchser,et al.  Spinal cord stimulation versus conventional medical management for neuropathic pain: A multicentre randomised controlled trial in patients with failed back surgery syndrome , 2007, Pain.

[27]  Soonman Kwon,et al.  An economic analysis of usual care and acupuncture collaborative treatment on chronic low back pain: A Markov model decision analysis , 2010, BMC complementary and alternative medicine.

[28]  M. Mychaskiw,et al.  PNP5 DIRECT COSTS OF BACK PAIN IN THE UNITED STATES:A NATIONAL ESTIMATE , 2002 .

[29]  A. Nordwall,et al.  2001 Volvo Award Winner in Clinical Studies: Lumbar Fusion Versus Nonsurgical Treatment for Chronic Low Back Pain: A Multicenter Randomized Controlled Trial From the Swedish Lumbar Spine Study Group , 2001, Spine.

[30]  R. Deyo,et al.  Costs and Cost-Effectiveness of Spinal Cord Stimulation (SCS) for Failed Back Surgery Syndrome: An Observational Study in a Workers' Compensation Population , 2011, Spine.

[31]  H. Tropp,et al.  Cost effectiveness of disc prosthesis versus lumbar fusion in patients with chronic low back pain: randomized controlled trial with 2-year follow-up , 2010, European Spine Journal.

[32]  M. T. Smolkin Medicare and cost-effectiveness analysis. , 2006, The New England journal of medicine.

[33]  R. Deyo,et al.  Cost‐Effectiveness of Lumbar Discectomy for the Treatment of Herniated Intervertebral Disc , 1996, Spine.

[34]  Harold Alan Pincus,et al.  The most expensive medical conditions in America. , 2002, Health affairs.

[35]  W. Halperin,et al.  Back pain prevalence in US industry and estimates of lost workdays. , 1999, American journal of public health.

[36]  P. Shekelle,et al.  Diagnosis and Treatment of Low Back Pain: A Joint Clinical Practice Guideline from the American College of Physicians and the American Pain Society , 2007, Annals of Internal Medicine.

[37]  S. Blond,et al.  [Cost-benefit evaluation of spinal cord stimulation treatment for failed-back surgery syndrome patients]. , 2004, Neuro-chirurgie.

[38]  M. Weinstein,et al.  Legislating against use of cost-effectiveness information. , 2010, The New England journal of medicine.

[39]  William Hollingworth,et al.  Spinal cord stimulation for failed back surgery syndrome: Outcomes in a workers’ compensation setting , 2010, PAIN.

[40]  Shoshannah A. Pearlman The Patient Protection and Affordable Care Act , 2013, Journal of the American Psychiatric Nurses Association.

[41]  Krishna Kumar,et al.  The Cost-effectiveness of Spinal Cord Stimulation in the Treatment of Failed Back Surgery Syndrome , 2010, The Clinical journal of pain.

[42]  J. Nicholl,et al.  Longer term clinical and economic benefits of offering acupuncture care to patients with chronic low back pain. , 2005, Health technology assessment.

[43]  Willem Van Mechelen,et al.  Effect of integrated care for sick listed patients with chronic low back pain: economic evaluation alongside a randomised controlled trial , 2010, BMJ : British Medical Journal.

[44]  S. Willich,et al.  Pragmatic randomized trial evaluating the clinical and economic effectiveness of acupuncture for chronic low back pain. , 2006, American journal of epidemiology.

[45]  Walter F. Stewart,et al.  Back Pain Exacerbations and Lost Productive Time Costs in United States Workers , 2006, Spine.

[46]  K. Strauch,et al.  Implementation of a Guideline for Low Back Pain Management in Primary Care: A Cost-Effectiveness Analysis , 2012, Spine.

[47]  C. Maher,et al.  Cost-effectiveness of guideline-endorsed treatments for low back pain: a systematic review , 2011, European Spine Journal.

[48]  S. Blond,et al.  Évaluation coût/bénéfice du traitement des lombosciatalgies post-opératoires par stimulation médullaire , 2004 .

[49]  Joseph S. Pliskin,et al.  Health Economic Evaluations: The Special Case of End-Stage Renal Disease Treatment , 2002, Medical decision making : an international journal of the Society for Medical Decision Making.

[50]  R. Hutubessy,et al.  WHO Guide for standardisation of economic evaluations of immunization programmes. , 2010, Vaccine.

[51]  Ron Goeree,et al.  Quality of life, resource consumption and costs of spinal cord stimulation versus conventional medical management in neuropathic pain patients with failed back surgery syndrome (PROCESS trial) , 2008, European journal of pain.

[52]  J. Wasserfallen,et al.  Cost-utility analysis of a three-month exercise programme vs usual care following multidisciplinary rehabilitation for chronic low back pain. , 2010, Journal of rehabilitation medicine.

[53]  J. Caro,et al.  A systematic review of low back pain cost of illness studies in the United States and internationally. , 2008, The spine journal : official journal of the North American Spine Society.

[54]  Jeremy Fairbank,et al.  Surgical stabilisation of the spine compared with a programme of intensive rehabilitation for the management of patients with chronic low back pain: cost utility analysis based on a randomised controlled trial , 2005, BMJ : British Medical Journal.

[55]  K. Budd Spinal Cord Stimulation: Cost‐Benefit Study , 2002, Neuromodulation : journal of the International Neuromodulation Society.

[56]  R. Taylor,et al.  Spinal Cord Stimulation versus Reoperation for Failed Back Surgery Syndrome: A Cost Effectiveness and Cost Utility Analysis Based on a Randomized, Controlled Trial , 2007, Neurosurgery.

[57]  S. Zenios,et al.  An empiric estimate of the value of life: updating the renal dialysis cost-effectiveness standard. , 2009, Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research.

[58]  J. Caro,et al.  Can cost utility evaluations inform decision making about interventions for low back pain? , 2009, The spine journal : official journal of the North American Spine Society.

[59]  J. Coast Is economic evaluation in touch with society's health values? , 2004, BMJ : British Medical Journal.

[60]  J. Rizzo,et al.  The labor productivity effects of chronic backache in the United States. , 1998, Medical care.

[61]  Norbert Donner-Banzhoff,et al.  Effects of Two Guideline Implementation Strategies on Patient Outcomes in Primary Care: A Cluster Randomized Controlled Trial , 2008, Spine.