Managing an outpatient parenteral antibiotic therapy team: challenges and solutions

Outpatient parenteral antimicrobial therapy (OPAT) programs should strive to deliver safe, cost effective, and high quality care. One of the keys to developing and sustaining a high quality OPAT program is to understand the common challenges or barriers to OPAT delivery. We review the most common challenges to starting and managing an OPAT program and give practical advice on addressing these issues.

[1]  C. O'rourke,et al.  Adverse events, healthcare interventions and healthcare utilization during home infusion therapy with daptomycin and vancomycin: a propensity score-matched cohort study. , 2014, The Journal of antimicrobial chemotherapy.

[2]  Lawrence P. Martinelli,et al.  Experience of infectious diseases consultants with outpatient parenteral antimicrobial therapy: results of an emerging infections network survey. , 2006, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[3]  R. Seaton,et al.  Risk factors for failure of outpatient parenteral antibiotic therapy (OPAT) in infective endocarditis , 2013, The Journal of antimicrobial chemotherapy.

[4]  D. Nathwani,et al.  Good practice recommendations for outpatient parenteral antimicrobial therapy (OPAT) in adults in the UK: a consensus statement. , 2012, The Journal of antimicrobial chemotherapy.

[5]  G. Allison,et al.  Are we ready for an outpatient parenteral antimicrobial therapy bundle? A critical appraisal of the evidence. , 2013, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[6]  Practice Guidelines for Outpatient Parenteral Antimicrobial Therapy , 2004 .

[7]  Brett H. Heintz,et al.  Impact of a Multidisciplinary Team Review of Potential Outpatient Parenteral Antimicrobial Therapy Prior to Discharge from an Academic Medical Center , 2011, The Annals of pharmacotherapy.

[8]  Amy S Nowacki,et al.  Association of laboratory test result availability and rehospitalizations in an outpatient parenteral antimicrobial therapy programme. , 2014, The Journal of antimicrobial chemotherapy.

[9]  P. Jewesson,et al.  Selecting Antibacterials for Outpatient Parenteral Antimicrobial Therapy , 2003, Clinical pharmacokinetics.

[10]  R. Seaton,et al.  Outpatient parenteral antibiotic therapy: principles and practice. , 2013, European journal of internal medicine.

[11]  A. Chapman,et al.  Patient retention of training in self-administration of intravenous antibiotic therapy in an outpatient parenteral antibiotic therapy service. , 2014, Journal of clinical nursing.

[12]  C. Weir,et al.  Factors associated with outcome and duration of therapy in outpatient parenteral antibiotic therapy (OPAT) patients with skin and soft-tissue infections. , 2011, International journal of antimicrobial agents.

[13]  S. Gordon,et al.  Contribution of infectious disease consultation toward the care of inpatients being considered for community-based parenteral anti-infective therapy. , 2012, Journal of hospital medicine.

[14]  B. Franklin,et al.  An outpatient parenteral antibiotic therapy (OPAT) map to identify risks associated with an OPAT service. , 2008, The Journal of antimicrobial chemotherapy.

[15]  C. Winnard,et al.  Antibiotic stewardship and early discharge from hospital: impact of a structured approach to antimicrobial management. , 2012, The Journal of antimicrobial chemotherapy.

[16]  Donald R Graham,et al.  Practice guidelines for outpatient parenteral antimicrobial therapy. IDSA guidelines. , 2004, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[17]  David M Kent,et al.  Prediction model for 30-day hospital readmissions among patients discharged receiving outpatient parenteral antibiotic therapy. , 2014, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[18]  Hien H. Nguyen.  Hospitalist to home: outpatient parenteral antimicrobial therapy at an academic center. , 2010, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[19]  Cathy Johnson,et al.  ASHP guidelines on home infusion pharmacy services. , 2014, American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists.

[20]  R. Seaton,et al.  Outpatient parenteral antimicrobial therapy (OPAT) in a teaching hospital-based practice: a retrospective cohort study describing experience and evolution over 10 years. , 2012, International journal of antimicrobial agents.