Sudden Unexpected Death in Patients with Epilepsy: Issues for Further Study

Summary: Understanding of mechanisms and the development of interventions to prevent sudden unexpected death in epilepsy (SUDEP) can be enhanced only through multicenter studies. Although current definitions are useful and congruent, there is insufficient guidance to allow others to duplicate studies. A working algorithm should be developed, preferably through review of current series, along with alternative definitions to allow external comparison with cardiovascular studies.

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