An open data ecosystem for cell migration research.

Cell migration research has recently become both a high content and a high throughput field thanks to technological, computational, and methodological advances. Simultaneously, however, urgent bioinformatics needs regarding data management, standardization, and dissemination have emerged. To address these concerns, we propose to establish an open data ecosystem for cell migration research.

[1]  Lennart Martens,et al.  The minimum information about a proteomics experiment (MIAPE) , 2007, Nature Biotechnology.

[2]  P. Friedl,et al.  The biology of cell locomotion within three-dimensional extracellular matrix , 2000, Cellular and Molecular Life Sciences CMLS.

[3]  Martin Eisenacher,et al.  The HUPO proteomics standards initiative- mass spectrometry controlled vocabulary , 2013, Database J. Biol. Databases Curation.

[4]  Democratizing proteomics data , 2007, Nature Biotechnology.

[5]  Anne E. Trefethen,et al.  Toward interoperable bioscience data , 2012, Nature Genetics.

[6]  M. Ashburner,et al.  An ontology for cell types , 2005, Genome Biology.

[7]  Erik Meijering,et al.  Methods for cell and particle tracking. , 2012, Methods in enzymology.

[8]  Lennart Martens,et al.  A posteriori quality control for the curation and reuse of public proteomics data , 2011, Proteomics.

[9]  K. Hulkower,et al.  Cell Migration and Invasion Assays as Tools for Drug Discovery , 2011, Pharmaceutics.

[10]  Lennart Martens,et al.  Do we want our data raw? Including binary mass spectrometry data in public proteomics data repositories , 2005, Proteomics.

[11]  P. Friedl,et al.  Collective cell migration in morphogenesis, regeneration and cancer , 2009, Nature Reviews Molecular Cell Biology.

[12]  Staffan Strömblad,et al.  Systems microscopy: an emerging strategy for the life sciences. , 2010, Experimental cell research.

[13]  James A. Eddy,et al.  In silico models of cancer , 2010, Wiley interdisciplinary reviews. Systems biology and medicine.

[14]  Li V. Yang,et al.  In vitro cell migration and invasion assays. , 2014, Journal of visualized experiments : JoVE.

[15]  P. Friedl,et al.  Preclinical intravital microscopy of the tumour-stroma interface: invasion, metastasis, and therapy response. , 2013, Current opinion in cell biology.