A dual functional chondro-inductive chitosan thermogel with high shear modulus and sustained drug release for cartilage tissue engineering.

[1]  J. Varshosaz,et al.  Effect of bassorin (derived from gum tragacanth) and halloysite nanotubes on physicochemical properties and the osteoconductivity of methylcellulose-based injectable hydrogels. , 2021, International journal of biological macromolecules.

[2]  H. Baharvand,et al.  A tough polysaccharide-based cell-laden double-network hydrogel promotes articular cartilage tissue regeneration in rabbits , 2021 .

[3]  H. Mirzadeh,et al.  Injectable and reversible preformed cryogels based on chemically crosslinked gelatin methacrylate (GelMA) and physically crosslinked hyaluronic acid (HA) for soft tissue engineering. , 2021, Colloids and surfaces. B, Biointerfaces.

[4]  M. Nasr-Esfahani,et al.  Chitosan/polycaprolactone multilayer hydrogel: A sustained Kartogenin delivery model for cartilage regeneration. , 2021, International journal of biological macromolecules.

[5]  H. Espinosa‐Andrews,et al.  Physically cross-linked chitosan-based hydrogels for tissue engineering applications: A state-of-the-art review , 2021 .

[6]  G. Cavallaro,et al.  Halloysite nanotubes filled with salicylic acid and sodium diclofenac: effects of vacuum pumping on loading and release properties , 2021, Journal of Nanostructure in Chemistry.

[7]  H. Ouyang,et al.  Advanced hydrogels for the repair of cartilage defects and regeneration , 2020, Bioactive materials.

[8]  H. Mirzadeh,et al.  Injectable drug loaded gelatin based scaffolds as minimally invasive approach for drug delivery system: CNC/PAMAM nanoparticles , 2020 .

[9]  P. Chu,et al.  A Biomimetic Nano‐Engineered Platform for Functional Tissue Engineering of Cartilage Superficial Zone , 2020, Advanced healthcare materials.

[10]  M. B. Eslaminejad,et al.  Dual functional construct containing kartogenin releasing microtissues and curcumin for cartilage regeneration , 2020, Stem Cell Research & Therapy.

[11]  L. Marin,et al.  New formulations based on salicyl-imine-chitosan hydrogels for prolonged drug release. , 2020, International journal of biological macromolecules.

[12]  Hongkai Wu,et al.  Injectable in situ forming kartogenin-loaded chitosan hydrogel with tunable rheological properties for cartilage tissue engineering. , 2020, Colloids and surfaces. B, Biointerfaces.

[13]  Shuai Zhang,et al.  Kartogenin mediates cartilage regeneration by stimulating the IL-6/Stat3-dependent proliferation of cartilage stem/progenitor cells. , 2020, Biochemical and biophysical research communications.

[14]  A. Akbarzadeh,et al.  An overview of various treatment strategies, especially tissue engineering for damaged articular cartilage , 2020, Artificial cells, nanomedicine, and biotechnology.

[15]  A. Hall The Role of Chondrocyte Morphology and Volume in Controlling Phenotype—Implications for Osteoarthritis, Cartilage Repair, and Cartilage Engineering , 2019, Current Rheumatology Reports.

[16]  Anuj Kumar,et al.  Enhanced physical, mechanical, and cytocompatibility behavior of polyelectrolyte complex hydrogels by reinforcing halloysite nanotubes and graphene oxide , 2019, Composites Science and Technology.

[17]  A. Solouk,et al.  Curcumin-Loaded Starch Micro/Nano Particles for Biomedical Application: The Effects of Preparation Parameters on Release Profile , 2019, Starch - Stärke.

[18]  Zhongqun Zhu,et al.  Kartogenin preconditioning commits mesenchymal stem cells to a precartilaginous stage with enhanced chondrogenic potential by modulating JNK and β‐catenin–related pathways , 2019, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[19]  Gaorui Cai,et al.  Recent advances in kartogenin for cartilage regeneration , 2019, Journal of drug targeting.

[20]  S. Shen,et al.  Intracellular pathway of halloysite nanotubes: potential application for antitumor drug delivery , 2018, Journal of Materials Science.

[21]  R. Oreffo,et al.  Clay nanoparticles for regenerative medicine and biomaterial design: A review of clay bioactivity. , 2018, Biomaterials.

[22]  K. Boheler,et al.  Facile formation of a microporous chitosan hydrogel based on self-crosslinking. , 2017, Journal of materials chemistry. B.

[23]  Hyun-Yong Lee,et al.  Layered Double Hydroxide and Polypeptide Thermogel Nanocomposite System for Chondrogenic Differentiation of Stem Cells. , 2017, ACS applied materials & interfaces.

[24]  Qiqing Zhang,et al.  Collagen-based porous scaffolds containing PLGA microspheres for controlled kartogenin release in cartilage tissue engineering , 2017, Artificial cells, nanomedicine, and biotechnology.

[25]  A. Solouk,et al.  Preparation and characterization of a composite biomaterial including starch micro/nano particles loaded chitosan gel. , 2017, Carbohydrate polymers.

[26]  V. Vinokurov,et al.  Paclitaxel Encapsulated in Halloysite Clay Nanotubes for Intestinal and Intracellular Delivery. , 2017, Journal of pharmaceutical sciences.

[27]  Yiwei Wang,et al.  Development of kartogenin-conjugated chitosan-hyaluronic acid hydrogel for nucleus pulposus regeneration. , 2017, Biomaterials science.

[28]  Wei Li,et al.  Microfluidic assembly of a nano-in-micro dual drug delivery platform composed of halloysite nanotubes and a pH-responsive polymer for colon cancer therapy. , 2017, Acta biomaterialia.

[29]  F. Zhang,et al.  In vitro proliferation and osteogenic differentiation of human dental pulp stem cells in injectable thermo-sensitive chitosan/β-glycerophosphate/hydroxyapatite hydrogel , 2016, Journal of biomaterials applications.

[30]  Ji-Eun Kim,et al.  Thermoresponsive nanospheres with independent dual drug release profiles for the treatment of osteoarthritis. , 2016, Acta biomaterialia.

[31]  Z. Shao,et al.  Enhancing the Gelation and Bioactivity of Injectable Silk Fibroin Hydrogel with Laponite Nanoplatelets. , 2016, ACS applied materials & interfaces.

[32]  Y. Lvov,et al.  Clay nanotube-biopolymer composite scaffolds for tissue engineering. , 2016, Nanoscale.

[33]  Liqun Zhang,et al.  Halloysite Clay Nanotubes for Loading and Sustained Release of Functional Compounds , 2016, Advanced materials.

[34]  D. Shi,et al.  Photo-Cross-Linked Scaffold with Kartogenin-Encapsulated Nanoparticles for Cartilage Regeneration. , 2016, ACS nano.

[35]  S. A. J. Jahromi,et al.  A study on role of nanosized SiO2 on deformation mechanism of vinyl ester , 2014, Bulletin of Materials Science.

[36]  J. Kim,et al.  Intra-articular delivery of kartogenin-conjugated chitosan nano/microparticles for cartilage regeneration. , 2014, Biomaterials.

[37]  P. Schultz,et al.  Mouse limb skeletal growth and synovial joint development are coordinately enhanced by Kartogenin. , 2014, Developmental biology.

[38]  J. Wang,et al.  Kartogenin induces cartilage-like tissue formation in tendon–bone junction , 2014, Bone Research.

[39]  Hongkai Wu,et al.  Microfluidic generation of chitosan/CpG oligodeoxynucleotide nanoparticles with enhanced cellular uptake and immunostimulatory properties. , 2014, Lab on a chip.

[40]  S Zaffagnini,et al.  Osteochondral scaffold reconstruction for complex knee lesions: a comparative evaluation. , 2013, The Knee.

[41]  I. Cumpstey Chemical Modification of Polysaccharides , 2013, ISRN organic chemistry.

[42]  Yuri Lvov,et al.  Halloysite clay nanotubes as a ceramic "skeleton" for functional biopolymer composites with sustained drug release. , 2013, Journal of materials chemistry. B.

[43]  Changren Zhou,et al.  Chitosan-halloysite nanotubes nanocomposite scaffolds for tissue engineering. , 2013, Journal of materials chemistry. B.

[44]  M. Rabišková,et al.  Diclofenac sodium entrapment and release from halloysite nanotubules. , 2013, Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti.

[45]  Mingxian Liu,et al.  Chitosan/halloysite nanotubes bionanocomposites: structure, mechanical properties and biocompatibility. , 2012, International journal of biological macromolecules.

[46]  Hua Wu,et al.  Chitosan-polycaprolactone copolymer microspheres for transforming growth factor-β1 delivery. , 2011, Colloids and surfaces. B, Biointerfaces.

[47]  R. Reis,et al.  Stimuli-responsive chitosan-starch injectable hydrogels combined with encapsulated adipose-derived stromal cells for articular cartilage regeneration , 2010 .

[48]  D. van der Kooy,et al.  A hydrogel-based stem cell delivery system to treat retinal degenerative diseases. , 2010, Biomaterials.

[49]  P. Giannoudis,et al.  NSAIDS inhibit in vitro MSC chondrogenesis but not osteogenesis: implications for mechanism of bone formation inhibition in man , 2010, Journal of cellular and molecular medicine.

[50]  Scott A. Rodeo,et al.  The Basic Science of Articular Cartilage , 2009, Sports health.

[51]  Y. Maugars,et al.  From osteoarthritis treatments to future regenerative therapies for cartilage. , 2009, Drug discovery today.

[52]  Robert Langer,et al.  Preparation of monodisperse biodegradable polymer microparticles using a microfluidic flow-focusing device for controlled drug delivery. , 2009, Small.

[53]  J. Feijen,et al.  Injectable chitosan-based hydrogels for cartilage tissue engineering. , 2009, Biomaterials.

[54]  Xufeng Niu,et al.  Preparation and characterization of an injectable composite , 2009, Journal of materials science. Materials in medicine.

[55]  G. Whitesides,et al.  Emulsification in a microfluidic flow-focusing device: effect of the viscosities of the liquids , 2008 .

[56]  Itai Cohen,et al.  Mapping the depth dependence of shear properties in articular cartilage. , 2007, Journal of biomechanics.

[57]  A. deMello Control and detection of chemical reactions in microfluidic systems , 2006, Nature.

[58]  D. Šubarić,et al.  Modification of wheat starch with succinic acid/acetanhydride and azelaic acid/acetanhydride mixtures. II. Chemical and physical properties , 2012, Journal of Food Science and Technology.

[59]  R. Reis,et al.  Chemical modification of starch based biodegradable polymeric blends: effects on water uptake, degradation behaviour and mechanical properties , 2000 .