Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions

M. J. Fresnadillo Martínez | H. Hakonarson | G. Schellenberg | J. Morris | C. DeCarli | D. Bennett | C. Cotman | J. Grafman | M. Mesulam | J. Trojanowski | J. Growdon | D. Perl | J. Hardy | S. Gilman | I. Ferrer | A. Levey | J. Hodges | J. Kaye | R. Mayeux | M. Sano | B. Boeve | J. Cummings | H. Feldman | S. DeKosky | D. Galasko | M. Grossman | E. Masliah | M. Frosch | D. Dickson | V. Lee | N. Cairns | B. Ghetti | E. Reiman | S. Arnold | H. Chui | C. van Broeckhoven | K. Welsh-Bohmer | E. Bigio | M. Gearing | D. Mann | C. Troakes | S. Al-Sarraj | H. Vinters | J. Kril | P. Hartikainen | J. Troncoso | P. Riederer | G. Halliday | J. Rohrer | I. Alafuzoff | D. Marson | P. Heutink | J. Lah | J. Kwok | N. Bogdanovic | T. Bird | Li-San Wang | T. Beach | M. Spillantini | H. Kretzschmar | J. Vonsattel | R. Rosenberg | N. Graff-Radford | A. McKee | D. Munoz | C. Hulette | R. Woltjer | I. Mackenzie | J. V. van Swieten | Stefanie H. Freeman | M. Martinez-Lage | P. Ince | P. Shaw | W. Ellis | S. Pickering-Brown | A. Lladó | A. Lieberman | V. V. Van Deerlin | J. van der Zee | A. L. de Munain | P. Sleiman | A. Chen-Plotkin | C. White | M. Neumann | B. Woodruff | R. Hamilton | S. Carroll | C. Miller | J. Murrell | S. Spina | D. Seilhean | S. Kumar-Singh | H. Seelaar | C. Mclean | T. Lashley | A. Alzualde | M. Tuñón | R. Rademakers | B. Miller | J. Schneider | V. V. van Deerlin | A. Mckee | C. Mclean | B. Miller | P. Shaw | J. Morris | J. Morris | M. Grossman | J. Hardy | J. Morris | J. Morris | J. Schneider | D. Bennett

[1]  S. Heath,et al.  Chromosome 9p-linked families with frontotemporal dementia associated with motor neuron disease , 2009, Neurology.

[2]  C. Broeckhoven,et al.  Granulin mutations associated with frontotemporal lobar degeneration and related disorders: An update , 2008, Human mutation.

[3]  J R Hodges,et al.  Incidence of early-onset dementias in Cambridgeshire, United Kingdom , 2008, Neurology.

[4]  J. Trojanowski,et al.  Variations in the progranulin gene affect global gene expression in frontotemporal lobar degeneration. , 2008, Human molecular genetics.

[5]  M. McCarthy,et al.  Genome-wide association studies for complex traits: consensus, uncertainty and challenges , 2008, Nature Reviews Genetics.

[6]  Marc Cruts,et al.  Loss of progranulin function in frontotemporal lobar degeneration. , 2008, Trends in genetics : TIG.

[7]  Ann B. Lee,et al.  On the use of general control samples for genome-wide association studies: genetic matching highlights causal variants. , 2008, American journal of human genetics.

[8]  L. Liang,et al.  A genome-wide association study of global gene expression , 2007, Nature Genetics.

[9]  Joseph T. Glessner,et al.  A genome-wide association study identifies KIAA0350 as a type 1 diabetes gene , 2007, Nature.

[10]  J. Trojanowski,et al.  Clinical, genetic, and pathologic characteristics of patients with frontotemporal dementia and progranulin mutations. , 2007, Archives of neurology.

[11]  J. Morris,et al.  TDP-43 in familial and sporadic frontotemporal lobar degeneration with ubiquitin inclusions. , 2007, The American journal of pathology.

[12]  J. Schneider,et al.  Neuropathologic diagnostic and nosologic criteria for frontotemporal lobar degeneration: consensus of the Consortium for Frontotemporal Lobar Degeneration , 2007, Acta Neuropathologica.

[13]  Simon C. Potter,et al.  Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls , 2007, Nature.

[14]  D. Reich,et al.  Population Structure and Eigenanalysis , 2006, PLoS genetics.

[15]  S. Melquist,et al.  Mutations in progranulin are a major cause of ubiquitin-positive frontotemporal lobar degeneration. , 2006, Human molecular genetics.

[16]  Bruce L. Miller,et al.  Ubiquitinated TDP-43 in Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis , 2006, Science.

[17]  C. Duijn,et al.  Null mutations in progranulin cause ubiquitin-positive frontotemporal dementia linked to chromosome 17q21 , 2006, Nature.

[18]  S. Melquist,et al.  Mutations in progranulin cause tau-negative frontotemporal dementia linked to chromosome 17 , 2006, Nature.

[19]  Jennifer Farmer,et al.  Frontotemporal dementia: Clinicopathological correlations , 2006, Annals of neurology.

[20]  Paul Scheet,et al.  A fast and flexible statistical model for large-scale population genotype data: applications to inferring missing genotypes and haplotypic phase. , 2006, American journal of human genetics.

[21]  G. Schellenberg,et al.  APOE and other loci affect age‐at‐onset in Alzheimer's disease families with PS2 mutation , 2005, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

[22]  M. Grossman,et al.  Frontotemporal Dementia:: Genetics and Genetic Counseling Dilemmas , 2004, The neurologist.

[23]  Kenneth S. Kosik,et al.  Apolipoprotein Eε4 modifies Alzheimer's disease onset in an E280A PS1 kindred , 2003 .

[24]  M. Stephens,et al.  Inference of population structure using multilocus genotype data: linked loci and correlated allele frequencies. , 2003, Genetics.

[25]  J R Hodges,et al.  The prevalence of frontotemporal dementia , 2002, Neurology.

[26]  Thomas D. Schmittgen,et al.  Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. , 2001, Methods.

[27]  B Miller,et al.  Clinical and pathological diagnosis of frontotemporal dementia: report of the Work Group on Frontotemporal Dementia and Pick's Disease. , 2001, Archives of neurology.

[28]  R. Faber,et al.  Frontotemporal lobar degeneration: a consensus on clinical diagnostic criteria. , 1999, Neurology.

[29]  E. Beutler Consensus recommendations , 1989, Infection Control & Hospital Epidemiology.

[30]  J. Trojanowski,et al.  Nomenclature for neuropathologic subtypes of frontotemporal lobar degeneration: consensus recommendations , 2008, Acta Neuropathologica.

[31]  G. Bedoya,et al.  Apolipoprotein Eepsilon4 modifies Alzheimer's disease onset in an E280A PS1 kindred. , 2003, Annals of neurology.

[32]  K. Johnson An Update. , 1984, Journal of food protection.