Bone marrow lesions: plugging the holes in our knowledge using animal models
暂无分享,去创建一个
[1] A. Guermazi,et al. Osteoarthritis Bone Marrow Lesions. , 2022, Osteoarthritis and cartilage.
[2] A. Pitsillides,et al. High bone mass in mice can be linked to lower osteoclast formation, resorptive capacity, and restricted in vitro sensitivity to inhibition by stable sulforaphane , 2022, Cell biochemistry and function.
[3] D. McWilliams,et al. The osteoarthritis bone score (OABS): a new histological scoring system for the characterisation of bone marrow lesions in osteoarthritis , 2022, Osteoarthritis and cartilage.
[4] M. Karperien,et al. Joint-on-chip platforms: entering a new era of in vitro models for arthritis , 2022, Nature Reviews Rheumatology.
[5] I. Amado. A novel osteochondral explant model to study bone and cartilage responses to damage in PTOA , 2021 .
[6] A. Simpson,et al. Optimization and Validation of a Human Ex Vivo Femoral Head Model for Preclinical Cartilage Research and Regenerative Therapies , 2020, Cartilage.
[7] Mark T Elliott,et al. The use of technology in the subcategorisation of osteoarthritis: a Delphi study approach , 2020, Osteoarthritis and cartilage open.
[8] D. Felson,et al. Association between Bone marrow lesions & synovitis and symptoms in symptomatic knee osteoarthritis , 2019, Osteoarthritis and cartilage.
[9] F. Cicuttini,et al. Bone Marrow Lesions in Knee Osteoarthritis: Regional Differences in Tibial Subchondral Bone Microstructure and their Association with Cartilage Degeneration. , 2019, Osteoarthritis and cartilage.
[10] A. Barbero,et al. Hyperphysiological compression of articular cartilage induces an osteoarthritic phenotype in a cartilage-on-a-chip model , 2019, Nature Biomedical Engineering.
[11] C. Chenu,et al. Noninvasive Mechanical Joint Loading as an Alternative Model for Osteoarthritic Pain , 2019, Arthritis & rheumatology.
[12] R. Todhunter,et al. Spontaneous dog osteoarthritis — a One Medicine vision , 2019, Nature Reviews Rheumatology.
[13] Y. Li,et al. Models of osteoarthritis: the good, the bad and the promising , 2019, Osteoarthritis and cartilage.
[14] J. Johnston,et al. Knee osteoarthritis patients with more subchondral cysts have altered tibial subchondral bone mineral density , 2019, BMC Musculoskeletal Disorders.
[15] M. Schramme,et al. Bone marrow lesions of the distal condyles of the third metacarpal bone are common and not always related to lameness in sports and pleasure horses , 2018, Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association.
[16] T. Maus,et al. Clinical magnetic resonance-enabled characterization of mono-iodoacetate-induced osteoarthritis in a large animal species , 2018, PloS one.
[17] D. Felson,et al. Bone marrow lesions in osteoarthritis: What lies beneath , 2018, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.
[18] C. Bozynski,et al. Subchondroplasty for the treatment of post‐traumatic bone marrow lesions of the medial femoral condyle in a pre‐clinical canine model , 2018, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.
[19] F. Cicuttini,et al. Bone matrix microdamage and vascular changes characterize bone marrow lesions in the subchondral bone of knee osteoarthritis. , 2018, Bone.
[20] D. Hunter,et al. Knee osteoarthritis phenotypes and their relevance for outcomes: a systematic review. , 2017, Osteoarthritis and cartilage.
[21] M. Koff,et al. An in vivo model of a mechanically-induced bone marrow lesion. , 2017, Journal of biomechanics.
[22] K. Chiu,et al. Is subchondral bone cyst formation in non-load-bearing region of osteoarthritic knee a vascular problem? , 2017, Medical hypotheses.
[23] Irina Vetter,et al. Methods Used to Evaluate Pain Behaviors in Rodents , 2017, Front. Mol. Neurosci..
[24] F. Howe,et al. Microarray analysis of bone marrow lesions in osteoarthritis demonstrates upregulation of genes implicated in osteochondral turnover, neurogenesis and inflammation , 2017, Annals of the rheumatic diseases.
[25] A. Pitsillides,et al. The STR/ort mouse model of spontaneous osteoarthritis – an update , 2017, Osteoarthritis and cartilage.
[26] K. Chiu,et al. Spontaneously Hypertensive Rat as a Novel Model of Co-morbid Knee Osteoarthritis , 2017 .
[27] J. Raya,et al. A novel rat model for subchondral microdamage in acute knee injury: a potential mechanism in post-traumatic osteoarthritis. , 2016, Osteoarthritis and cartilage.
[28] S. Mclure,et al. Osteoarthritic bone marrow lesions almost exclusively colocate with denuded cartilage: a 3D study using data from the Osteoarthritis Initiative. , 2016, Annals of the Rheumatic Diseases.
[29] David M Findlay,et al. Bone–cartilage crosstalk: a conversation for understanding osteoarthritis , 2016, Bone Research.
[30] F. Cicuttini,et al. Bone marrow lesions detected by specific combination of MRI sequences are associated with severity of osteochondral degeneration , 2016, Arthritis Research & Therapy.
[31] F. Ponchel,et al. Mesenchymal Stem Cell Alterations in Bone Marrow Lesions in Patients With Hip Osteoarthritis , 2016, Arthritis & rheumatology.
[32] E. Eriksen. Treatment of bone marrow lesions (bone marrow edema). , 2015, BoneKEy reports.
[33] F. Guilak,et al. Non-invasive mouse models of post-traumatic osteoarthritis. , 2015, Osteoarthritis and cartilage.
[34] S. Kingsbury,et al. A systematic review of the relationship between subchondral bone features, pain and structural pathology in peripheral joint osteoarthritis , 2015, Arthritis Research & Therapy.
[35] F. Cicuttini,et al. Association of patellar bone marrow lesions with knee pain, patellar cartilage defect and patellar cartilage volume loss in older adults: a cohort study. , 2015, Osteoarthritis and cartilage.
[36] A. McCoy. Animal Models of Osteoarthritis , 2015, Veterinary pathology.
[37] A. Pitsillides,et al. Intermittent applied mechanical loading induces subchondral bone thickening that may be intensified locally by contiguous articular cartilage lesions , 2015, Osteoarthritis and cartilage.
[38] C. Bozynski,et al. Development of a Novel Canine Model for Posttraumatic Osteoarthritis of the Knee , 2015, The Journal of Knee Surgery.
[39] D. Beckwée,et al. The Influence of Joint Loading on Bone Marrow Lesions in the Knee , 2015, The American journal of sports medicine.
[40] Philip G. Conaghan,et al. Impact and therapy of osteoarthritis: the Arthritis Care OA Nation 2012 survey , 2015, Clinical Rheumatology.
[41] D. A. van der Windt,et al. Pain trajectory groups in persons with, or at high risk of, knee osteoarthritis: findings from the Knee Clinical Assessment Study and the Osteoarthritis Initiative , 2014, Osteoarthritis and cartilage.
[42] Wen-zhi Chen,et al. Magnetic Resonance Imaging of Osteophytic, Chondral, and Subchondral Structures in a Surgically-Induced Osteoarthritis Rabbit Model , 2014, PloS one.
[43] C. Rimnac,et al. Quantitative relationships between microdamage and cancellous bone strength and stiffness. , 2014, Bone.
[44] J. Collins,et al. Bone marrow–on–a–chip replicates hematopoietic niche physiology in vitro , 2014, Nature Methods.
[45] F. Cicuttini,et al. Association of obesity and systemic factors with bone marrow lesions at the knee: a systematic review. , 2014, Seminars in arthritis and rheumatism.
[46] M. Thali,et al. Essentials of forensic post-mortem MR imaging in adults. , 2014, The British journal of radiology.
[47] Tan Hwee Chye Andrew,et al. The Truth Behind Subchondral Cysts in Osteoarthritis of the Knee , 2014, The open orthopaedics journal.
[48] W. Lems,et al. Three trajectories of activity limitations in early symptomatic knee osteoarthritis: a 5-year follow-up study , 2013, Annals of the rheumatic diseases.
[49] K Henriksen,et al. Osteoarthritis--a case for personalized health care? , 2014, Osteoarthritis and cartilage.
[50] C. Rimnac,et al. Microdamage Caused by Fatigue Loading in Human Cancellous Bone: Relationship to Reductions in Bone Biomechanical Performance , 2013, PloS one.
[51] S. Majumdar,et al. Association of cartilage defects, and other MRI findings with pain and function in individuals with mild-moderate radiographic hip osteoarthritis and controls. , 2013, Osteoarthritis and cartilage.
[52] M. Chou,et al. Sequential Change in T2* Values of Cartilage, Meniscus, and Subchondral Bone Marrow in a Rat Model of Knee Osteoarthritis , 2013, PloS one.
[53] Jincheng Pang,et al. Bone marrow lesion volume reduction is not associated with improvement of other periarticular bone measures: data from the Osteoarthritis Initiative , 2013, Arthritis Research & Therapy.
[54] F. Cicuttini,et al. Are biomechanical factors, meniscal pathology, and physical activity risk factors for bone marrow lesions at the knee? A systematic review. , 2013, Seminars in arthritis and rheumatism.
[55] Jincheng Pang,et al. Evaluation of bone marrow lesion volume as a knee osteoarthritis biomarker - longitudinal relationships with pain and structural changes: data from the Osteoarthritis Initiative , 2013, Arthritis Research & Therapy.
[56] Neil A Segal,et al. The Multicenter Osteoarthritis Study: Opportunities for Rehabilitation Research , 2013, PM & R : the journal of injury, function, and rehabilitation.
[57] T. Wright,et al. In vivo cyclic compression causes cartilage degeneration and subchondral bone changes in mouse tibiae. , 2013, Arthritis and rheumatism.
[58] L. Riley,et al. Inhibition of TGF–β signaling in subchondral bone mesenchymal stem cells attenuates osteoarthritis , 2013, Nature Medicine.
[59] Felix Eckstein,et al. Quantification of bone marrow lesion volume and volume change using semi-automated segmentation: data from the osteoarthritis initiative , 2013, BMC Musculoskeletal Disorders.
[60] S. Majumdar,et al. Bone and cartilage demonstrate changes localized to bone marrow edema-like lesions within osteoarthritic knees. , 2013, Osteoarthritis and cartilage.
[61] L. Beenen,et al. Postmortem imaging exposed: an aid in MR imaging of musculoskeletal structures , 2013, Skeletal Radiology.
[62] A. Silman,et al. Mapping pathogenesis of arthritis through small animal models. , 2012, Rheumatology.
[63] L. Sharma,et al. Knee malalignment is associated with an increased risk for incident and enlarging bone marrow lesions in the more loaded compartments: the MOST study. , 2012, Osteoarthritis and cartilage.
[64] D. Felson,et al. Magnetic resonance imaging of subchondral bone marrow lesions in association with osteoarthritis. , 2012, Seminars in arthritis and rheumatism.
[65] B. Christiansen,et al. Musculoskeletal changes following non-invasive knee injury using a novel mouse model of post-traumatic osteoarthritis. , 2012, Osteoarthritis and cartilage.
[66] O. Weber,et al. The influence of body temperature on image contrast in post mortem MRI. , 2012, European journal of radiology.
[67] D. Zani,et al. Magnetic resonance imaging findings of bone marrow lesions in the equine distal tarsus , 2012 .
[68] J. Gati,et al. An in vivo investigation of the initiation and progression of subchondral cysts in a rodent model of secondary osteoarthritis , 2012, Arthritis Research & Therapy.
[69] L. Laslett,et al. Zoledronic acid reduces knee pain and bone marrow lesions over 1 year: a randomised controlled trial , 2012, Annals of the rheumatic diseases.
[70] R. Boudreau,et al. Evolution of semi-quantitative whole joint assessment of knee OA: MOAKS (MRI Osteoarthritis Knee Score). , 2011, Osteoarthritis and cartilage.
[71] Ali Guermazi,et al. Advances in imaging of osteoarthritis and cartilage. , 2011, Radiology.
[72] V. Busoni,et al. Impact of successive freezing-thawing cycles on 3-T magnetic resonance images of the digits of isolated equine limbs. , 2011, American journal of veterinary research.
[73] Ali Guermazi,et al. Fluctuation of knee pain and changes in bone marrow lesions, effusions, and synovitis on magnetic resonance imaging. , 2011, Arthritis and rheumatism.
[74] T. Huizinga,et al. Do knee abnormalities visualised on MRI explain knee pain in knee osteoarthritis? A systematic review , 2010, Annals of the rheumatic diseases.
[75] A. Pitsillides,et al. Characterizing a novel and adjustable noninvasive murine joint loading model. , 2011, Arthritis and rheumatism.
[76] G. Zhai,et al. Bone marrow lesions predict site-specific cartilage defect development and volume loss: a prospective study in older adults , 2010, Arthritis Research & Therapy.
[77] F. Berenbaum. The OARSI histopathology initiative - the tasks and limitations. , 2010, Osteoarthritis and cartilage.
[78] K. Kaneko,et al. A longitudinal study of the relationship between the status of bone marrow abnormalities and progression of knee osteoarthritis , 2010, Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association.
[79] D. Felson,et al. Subchondral cystlike lesions develop longitudinally in areas of bone marrow edema-like lesions in patients with or at risk for knee osteoarthritis: detection with MR imaging--the MOST study. , 2010, Radiology.
[80] R. Zernicke,et al. In vivo microfocal computed tomography and micro-magnetic resonance imaging evaluation of antiresorptive and antiinflammatory drugs as preventive treatments of osteoarthritis in the rat. , 2010, Arthritis and rheumatism.
[81] Johanne Martel-Pelletier,et al. Relationship between bone marrow lesions, cartilage loss and pain in knee osteoarthritis: results from a randomised controlled clinical trial using MRI , 2010, Annals of the rheumatic diseases.
[82] D. Felson,et al. Contrast-enhanced MRI of subchondral cysts in patients with or at risk for knee osteoarthritis: the MOST study. , 2010, European journal of radiology.
[83] F. Cicuttini,et al. Meniscal extrusion predicts increases in subchondral bone marrow lesions and bone cysts and expansion of subchondral bone in osteoarthritic knees. , 2010, Rheumatology.
[84] D. English,et al. Development of bone marrow lesions is associated with adverse effects on knee cartilage while resolution is associated with improvement - a potential target for prevention of knee osteoarthritis: a longitudinal study , 2010, Arthritis research & therapy.
[85] J. Griffith,et al. Pitfalls in interpreting rat knee joint magnetic resonance images and their histological correlation , 2009, Acta radiologica.
[86] M. Nevitt,et al. Tibiofemoral joint osteoarthritis: risk factors for MR-depicted fast cartilage loss over a 30-month period in the multicenter osteoarthritis study. , 2009, Radiology.
[87] Bejoy Thomas,et al. Principles, techniques, and applications of T2*-based MR imaging and its special applications. , 2009, Radiographics : a review publication of the Radiological Society of North America, Inc.
[88] A Guermazi,et al. MRI-detected subchondral bone marrow signal alterations of the knee joint: terminology, imaging appearance, relevance and radiological differential diagnosis. , 2009, Osteoarthritis and cartilage.
[89] Nicola Vanello,et al. Biological Effects and Safety in Magnetic Resonance Imaging: A Review , 2009, International journal of environmental research and public health.
[90] A. Guermazi,et al. MRI-based semiquantitative assessment of subchondral bone marrow lesions in osteoarthritis research. , 2009, Osteoarthritis and cartilage.
[91] G. Beauchamp,et al. Use of routine clinical multimodality imaging in a rabbit model of osteoarthritis--part I. , 2009, Osteoarthritis and cartilage.
[92] J. Raynauld,et al. Temporal assessment of bone marrow lesions on magnetic resonance imaging in a canine model of knee osteoarthritis: impact of sequence selection. , 2008, Osteoarthritis and cartilage.
[93] N. Kettner,et al. Bone marrow edema: pathophysiology, differential diagnosis, and imaging , 2008, Acta radiologica.
[94] J. Bloem,et al. Do MRI features at baseline predict radiographic joint space narrowing in the medial compartment of the osteoarthritic knee 2 years later? , 2008, Skeletal Radiology.
[95] J. Craig,et al. Bone marrow edema in the knee in osteoarthrosis and association with total knee arthroplasty within a three-year follow-up , 2008, Skeletal Radiology.
[96] E. Krupinski,et al. Bone marrow edema pattern in advanced hip osteoarthritis: quantitative assessment with magnetic resonance imaging and correlation with clinical examination, radiographic findings, and histopathology , 2008, Skeletal Radiology.
[97] J. Raynauld,et al. Magnetic resonance imaging can accurately assess the long-term progression of knee structural changes in experimental dog osteoarthritis , 2007, Annals of the rheumatic diseases.
[98] J F Beary,et al. Correlation between bone lesion changes and cartilage volume loss in patients with osteoarthritis of the knee as assessed by quantitative magnetic resonance imaging over a 24-month period , 2007, Annals of the rheumatic diseases.
[99] A. Guermazi,et al. The reliability of a new scoring system for knee osteoarthritis MRI and the validity of bone marrow lesion assessment: BLOKS (Boston–Leeds Osteoarthritis Knee Score) , 2007, Annals of the rheumatic diseases.
[100] Ali Guermazi,et al. Correlation of the development of knee pain with enlarging bone marrow lesions on magnetic resonance imaging. , 2007, Arthritis and rheumatism.
[101] J. Lang,et al. MRI characteristics and histology of bone marrow lesions in dogs with experimentally induced osteoarthritis. , 2007, Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association.
[102] J. Parellada,et al. MRI of bone marrow edema-like signal in the pathogenesis of subchondral cysts. , 2006, Osteoarthritis and cartilage.
[103] J. Bloem,et al. Osteoarthritis of the knee: association between clinical features and MR imaging findings. , 2006, Radiology.
[104] Ali Guermazi,et al. Increase in bone marrow lesions associated with cartilage loss: a longitudinal magnetic resonance imaging study of knee osteoarthritis. , 2006, Arthritis and rheumatism.
[105] C. Hayes,et al. Osteoarthritis of the knee: comparison of MR imaging findings with radiographic severity measurements and pain in middle-aged women. , 2005, Radiology.
[106] J. Bloem,et al. MRI assessment of knee osteoarthritis: Knee Osteoarthritis Scoring System (KOSS)—inter-observer and intra-observer reproducibility of a compartment-based scoring system , 2005, Skeletal Radiology.
[107] H. Genant,et al. Whole-Organ Magnetic Resonance Imaging Score (WORMS) of the knee in osteoarthritis. , 2004, Osteoarthritis and cartilage.
[108] Sharmila Majumdar,et al. Osteoarthritis: MR imaging findings in different stages of disease and correlation with clinical findings. , 2003, Radiology.
[109] B. Hansen. Assessment of pain in dogs: veterinary clinical studies. , 2003, ILAR journal.
[110] L. Kazis,et al. The Association of Bone Marrow Lesions with Pain in Knee Osteoarthritis , 2001, Annals of Internal Medicine.
[111] M. Zanetti,et al. Bone marrow edema pattern in osteoarthritic knees: correlation between MR imaging and histologic findings. , 2000, Radiology.
[112] P. Rumph,et al. Low-field magnetic resonance imaging of early subchondral cyst-like lesions in induced cranial cruciate ligament deficient dogs. , 1998, Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association.
[113] O. Svensson,et al. Correlation of morphologic and biochemical changes in the natural history of spontaneous osteoarthrosis in guinea pigs. , 1997, Arthritis and rheumatism.
[114] T. Chambers,et al. Angiotensin II is generated from angiotensin I by bone cells and stimulates osteoclastic bone resorption in vitro. , 1997, The Journal of endocrinology.
[115] F. Reinholt,et al. Focal destruction and remodeling in guinea pig arthrosis. , 1996, Acta orthopaedica Scandinavica.
[116] L D Hall,et al. Degenerative joint disease in the guinea pig. Use of magnetic resonance imaging to monitor progression of bone pathology. , 1996, Arthritis and rheumatism.
[117] G. Adam,et al. MRI of degenerative bone marrow lesions in experimental osteoarthritis of canine knee joints , 1996, Skeletal Radiology.
[118] L. Donahue,et al. Genetic variability in adult bone density among inbred strains of mice. , 1996, Bone.
[119] R. Parkkola,et al. The effects of the method of death and lapsed time on proton relaxation time T1 in autopsied muscle samples. , 1993, Investigative radiology.
[120] A. Bendele,et al. Effects of body weight restriction on the development and progression of spontaneous osteoarthritis in guinea pigs. , 1991, Arthritis and rheumatism.
[121] A. Wilson,et al. Transient osteoporosis: transient bone marrow edema? , 1988, Radiology.
[122] M. Walton. Degenerative joint disease in the mouse knee; radiological and morphological observations , 1977, The Journal of pathology.
[123] D Resnick,et al. Subchondral cysts (geodes) in arthritic disorders: pathologic and radiographic appearance of the hip joint. , 1977, AJR. American journal of roentgenology.
[124] W. M. Rogers,et al. Vascular foramina and arterial supply of the distal end of the femur. , 1950, The Journal of bone and joint surgery. American volume.