Trend analysis of the sex ratio at birth in the United States.

OBJECTIVES This report presents total sex ratios at birth from 1940 to 2002, for race starting in 1970, for Hispanic origin groups starting in 1989, for live birth order starting in 1943, and for age of mother for the full time period. METHODS Descriptive tabulations of sex ratios using the birth data set are presented and interpreted. Joinpoint regression analysis is used to detect changes in the sex ratio over time. RESULTS The United States sex ratio at birth had three significant transitions from 1940 to 2002 (1942, 1959, and 1971). White women were the only race group to have any significant changes in the sex ratio between 1970 and 2002 (1972, 1976, and 1988). Between 1940 and 2002 significant transitions in sex ratios occurred to women aged 20-24 (1942, 1966, 1974, and 1987); 25-29 (1961 and 1968); 35-39 (1965 and 1976); and 40-44 years (1967).

[1]  H. Møller.  Change in male:female ratio among newborn infants in Denmark , 1996, The Lancet.

[2]  E. Sondik.  Atlas of United States Mortality , 1990 .

[3]  Ahmedin Jemal,et al.  Annual Report to the Nation on the status of cancer, 1973–1999, featuring implications of age and aging on U.S. cancer burden , 2002, Cancer.

[4]  F. Menacker,et al.  Infant mortality statistics from the 2002 period: linked birth/infant death data set. , 2004, National vital statistics reports : from the Centers for Disease Control and Prevention, National Center for Health Statistics, National Vital Statistics System.

[5]  R. Mizuno.  The male/female ratio of fetal deaths and births in Japan , 2000, The Lancet.

[6]  M. Feinleib.  National Center for Health Statistics (NCHS) , 2005 .

[7]  R. Jacobsen,et al.  Fertility rates in Denmark in relation to the sexes of preceding children in the family. , 1999, Human Reproduction.

[8]  J W Cullen,et al.  Cancer prevention and control. , 1994, Seminars in oncology.

[9]  R. Biggar,et al.  Sex ratios, family size, and birth order. , 1999, American journal of epidemiology.

[10]  M. Mcgeehin,et al.  Changing sex ratio in the United States, 1969-1995. , 1998, Fertility and sterility.

[11]  D. Amre,et al.  Maternal and Obstetric Risk Factors for Sudden Infant Death Syndrome in the United States , 2004, Obstetrics and gynecology.

[12]  J. A. Martin,et al.  Births of Hispanic origin, 1989-95. , 1998, Monthly vital statistics report.

[13]  T. Yoshimura,et al.  Sex ratio in offspring of those affected by dioxin and dioxin-like compounds: the Yusho, Seveso, and Yucheng incidents , 2001, Occupational and environmental medicine.

[14]  Trends in drinking among Americans age 18 and younger: 1975-2002. , 2004, Alcoholism, clinical and experimental research.

[15]  C D Humfrey,et al.  Reproductive health in humans and wildlife: are adverse trends associated with environmental chemical exposure? , 1997, The Science of the total environment.

[16]  M. Nicolich,et al.  Influence of parental and biological factors on the male birth fraction in the United States: an analysis of birth certificate data from 1964 through 1988. , 2000, Fertility and sterility.

[17]  E. Fernández,et al.  Recent decline in cancer mortality in Catalonia (Spain). A joinpoint regression analysis. , 2001, European journal of cancer.

[18]  W. Petersen,et al.  Dictionary of demography : terms, concepts, and institutions , 1986 .

[19]  W. James.  Analysing data on the sex ratio of human births by cycle day of conception. , 2000, Human reproduction.

[20]  A. Cagnacci,et al.  Influences of maternal weight on the secondary sex ratio of human offspring. , 2004, Human reproduction.

[21]  Age , 2000, BMJ : British Medical Journal.

[22]  J. J. Ryan,et al.  Sex ratios of children of Russian pesticide producers exposed to dioxin. , 2002, Environmental health perspectives.

[23]  J. F. Martin.  Length of the follicular phase, time of insemination, coital rate and the sex of offspring. , 1997, Human reproduction.

[24]  R. Jacobsen.  Parental ages and the secondary sex ratio. , 2001, Human reproduction.

[25]  W. James,et al.  The human sex ratio. Part 1: A review of the literature. , 1987, Human biology.

[26]  M. Fukuda,et al.  Decline in sex ratio at birth after Kobe earthquake. , 1998, Human reproduction.

[27]  E. Feuer,et al.  Permutation tests for joinpoint regression with applications to cancer rates. , 2000, Statistics in medicine.

[28]  Declining Trends of Male Proportion at Birth in Europe , 2001, Archives of environmental health.

[29]  J. Toppari,et al.  Sexual differentiation and environmental endocrine disrupters. , 1998, Bailliere's clinical endocrinology and metabolism.

[30]  W. James.  The variation of the probability of a son within and across couples. , 2000, Human reproduction.

[31]  C R Bauer,et al.  Sex differences in outcomes of very low birthweight infants: the newborn male disadvantage , 2000, Archives of disease in childhood. Fetal and neonatal edition.

[32]  B. Gu,et al.  Sex ratio at birth in China, with reference to other areas in East Asia: what we know. , 1995, Asia-Pacific population journal.

[33]  Donna L. Hoyert,et al.  Vital Statistics of the United States , 1940, Nature.

[34]  Takashi Shimizu,et al.  Parental periconceptional smoking and male: female ratio of newborn infants , 2002, The Lancet.

[35]  J. Lazarus.  Sex Ratios: Human sex ratios: adaptations and mechanisms, problems and prospects , 2002 .

[36]  J. Martin,et al.  Births: final data for 2002. , 2003, National vital statistics reports : from the Centers for Disease Control and Prevention, National Center for Health Statistics, National Vital Statistics System.

[37]  R. Catalano,et al.  Sex ratios in the two Germanies: a test of the economic stress hypothesis. , 2003, Human reproduction.

[38]  D. Davis,et al.  Reduced ratio of male to female births in several industrial countries: a sentinel health indicator? , 1998, JAMA.

[39]  H. Orvos,et al.  Natural variation in the human sex ratio. , 2001, Human reproduction.

[40]  A. Jemal,et al.  Annual report to the nation on the status of cancer, 1975-2000, featuring the uses of surveillance data for cancer prevention and control. , 2003, Journal of the National Cancer Institute.