Encephalitis Caused by Jamestown Canyon Virus in a Liver Transplant Patient, North Carolina, USA, 2017

Abstract We describe the first documented case of Jamestown Canyon virus (JCV) in North Carolina, which occurred in a liver transplant patient who presented acutely with headache, aphasia, and confusion. This is also the first report of recovery from JCV encephalitis following treatment with intravenous immune globulin.

[1]  P. Ellis,et al.  Hazardous substances , 2020, CDM 2015 Questions and Answers.

[2]  Pardis C Sabeti,et al.  Fatal Case of Chronic Jamestown Canyon Virus Encephalitis Diagnosed by Metagenomic Sequencing in Patient Receiving Rituximab , 2020, Emerging infectious diseases.

[3]  S. Kanjilal,et al.  Diagnostic Approach for Arboviral Infections in the United States , 2020, Journal of Clinical Microbiology.

[4]  J. Fishman,et al.  Immunosuppressive Agents and Infectious Risk in Transplantation: Managing the "Net State of Immunosuppression". , 2020, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[5]  Pardis C Sabeti,et al.  Jamestown Canyon virus in Massachusetts: clinical case series and vector screening , 2020, Emerging microbes & infections.

[6]  V. Thohan,et al.  Jamestown Canyon virus encephalitis in a heart transplant patient , 2019, Transplant infectious disease : an official journal of the Transplantation Society.

[7]  H. Masur,et al.  Lack of Efficacy of High-Titered Immunoglobulin in Patients with West Nile Virus Central Nervous System Disease , 2019, Emerging infectious diseases.

[8]  M. Fischer,et al.  West Nile Virus and Other Domestic Nationally Notifiable Arboviral Diseases — United States, 2018 , 2019, MMWR. Morbidity and mortality weekly report.

[9]  S. Hills,et al.  West Nile Virus and Other Nationally Notifiable Arboviral Diseases — United States, 2017 , 2018, MMWR. Morbidity and mortality weekly report.

[10]  J. E. Staples,et al.  West Nile Virus and Other Nationally Notifiable Arboviral Diseases — United States, 2016 , 2018, MMWR. Morbidity and mortality weekly report.

[11]  A. Kribben,et al.  Renal Transplant Recipients Treated with Calcineurin-Inhibitors Lack Circulating Immature Transitional CD19+CD24hiCD38hi Regulatory B-Lymphocytes , 2016, PloS one.

[12]  J. Lawo,et al.  Quantitative Evidence of Wear-Off Effect at the End of the Intravenous IgG (IVIG) Dosing Cycle in Primary Immunodeficiency , 2016, Journal of Clinical Immunology.

[13]  Jennifer L. White,et al.  Jamestown Canyon Virus Disease in the United States-2000-2013. , 2015, The American journal of tropical medicine and hygiene.

[14]  G. Palù,et al.  Latest developments and challenges in the diagnosis of human West Nile virus infection , 2015, Expert review of anti-infective therapy.

[15]  J. E. Staples,et al.  Medical risk factors for severe West Nile Virus disease, United States, 2008-2010. , 2012, The American journal of tropical medicine and hygiene.

[16]  F. Bonilla Pharmacokinetics of immunoglobulin administered via intravenous or subcutaneous routes. , 2008, Immunology and allergy clinics of North America.

[17]  M. Malkoff,et al.  Risk factors for encephalitis and death from West Nile virus infection , 2006, Epidemiology and Infection.

[18]  N. Karabatsos,et al.  Jamestown Canyon virus: seroprevalence in Connecticut. , 2001, Emerging infectious diseases.