In Silico Prediction of Peptides Binding to Multiple HLA-DR Molecules Accurately Identifies Immunodominant Epitopes from gp43 of Paracoccidioides brasiliensis Frequently Recognized in Primary Peripheral Blood Mononuclear Cell Responses from Sensitized Individuals

[1]  L. Travassos,et al.  The gp43 from Paracoccidioides brasiliensis: A Major Diagnostic Antigen and Vaccine Candidate , 2004 .

[2]  Hans-Georg Rammensee,et al.  MHC ligands and peptide motifs: first listing , 2004, Immunogenetics.

[3]  R. Schroers,et al.  Identification of a MHC class-II restricted epitope in carcinoembryonic antigen , 2004, Cancer Immunology, Immunotherapy.

[4]  R. Longhi,et al.  CD4(+) T cells from healthy subjects and colon cancer patients recognize a carcinoembryonic antigen-specific immunodominant epitope. , 2003, Cancer research.

[5]  A. Nesburn,et al.  Identification of Novel Immunodominant CD4+ Th1-Type T-Cell Peptide Epitopes from Herpes Simplex Virus Glycoprotein D That Confer Protective Immunity , 2003, Journal of Virology.

[6]  Zhen Xiao,et al.  Identification of MHC class II-restricted T-cell epitopes in prostate-specific membrane antigen. , 2003, Clinical cancer research : an official journal of the American Association for Cancer Research.

[7]  F. Sallusto,et al.  Proliferation and differentiation potential of human CD8+ memory T-cell subsets in response to antigen or homeostatic cytokines. , 2003, Blood.

[8]  C. Rooney,et al.  Identification of a Naturally Processed HLA-DR–Restricted T-Helper Epitope in Epstein-Barr Virus Nuclear Antigen Type 1 , 2003, Journal of immunotherapy.

[9]  W. Alvord,et al.  Adjuvant immunization of HLA-A2-positive melanoma patients with a modified gp100 peptide induces peptide-specific CD8+ T-cell responses. , 2003, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[10]  J. Reidhaar-Olson,et al.  The use of bioinformatics for identifying class II-restricted T-cell epitopes. , 2003, Methods.

[11]  M. Taubman,et al.  Immunogenicity and Protective Immunity Induced by Synthetic Peptides Associated with Putative Immunodominant Regions of Streptococcus mutans Glucan-Binding Protein B , 2003, Infection and Immunity.

[12]  Angela Bachi,et al.  Identification of immunodominant regions among promiscuous HLA-DR-restricted CD4+ T-cell epitopes on the tumor antigen MAGE-3. , 2003, Blood.

[13]  Ying-hua Chen,et al.  Candidate peptide vaccine induced protection against classical swine fever virus. , 2002, Vaccine.

[14]  A. Sette,et al.  A Decaepitope Polypeptide Primes for Multiple CD8+ IFN-γ and Th Lymphocyte Responses: Evaluation of Multiepitope Polypeptides as a Mode for Vaccine Delivery1 , 2002, The Journal of Immunology.

[15]  Jingwu Z. Zhang,et al.  Identification of HLA DR7-restricted epitopes from human telomerase reverse transcriptase recognized by CD4+ T-helper cells. , 2002, Cancer research.

[16]  Fabio Grassi,et al.  Identification of a Promiscuous T-Cell Epitope in Mycobacterium tuberculosis Mce Proteins , 2002, Infection and Immunity.

[17]  M. Tsuji,et al.  Peptide-based subunit vaccines against pre-erythrocytic stages of malaria parasites. , 2001, Molecular immunology.

[18]  W. Pichler,et al.  Perspectives: towards a peptide-based vaccine against hepatitis C virus. , 2001, Molecular immunology.

[19]  R. Meloen,et al.  Synthetic peptide vaccines: unexpected fulfillment of discarded hope? , 2001, Biologicals : journal of the International Association of Biological Standardization.

[20]  A. Sette,et al.  T-Cell Reactivity against Streptococcal Antigens in the Periphery Mirrors Reactivity of Heart-Infiltrating T Lymphocytes in Rheumatic Heart Disease Patients , 2001, Infection and Immunity.

[21]  M. Zöller,et al.  T-helper cell-response to MHC class II-binding peptides of the renal cell carcinoma-associated antigen RAGE-1. , 2001, Immunobiology.

[22]  J. McEwen,et al.  The habitat of Paracoccidioides brasiliensis: how far from solving the riddle? , 2001, Medical mycology.

[23]  John Sidney,et al.  Measurement of MHC/Peptide Interactions by Gel Filtration , 1999, Current protocols in immunology.

[24]  L Raddrizzani,et al.  In Vitro and In Vivo Induction of a Th Cell Response Toward Peptides of the Melanoma-Associated Glycoprotein 100 Protein Selected by the TEPITOPE Program1 , 2000, The Journal of Immunology.

[25]  G. Benard,et al.  Anti-Idiotypic Antibodies in Patients with Different Clinical Forms of Paracoccidioidomycosis , 2000, Clinical Diagnostic Laboratory Immunology.

[26]  S. A. Palácios,et al.  Evaluation of tests for antibody response in the follow-up of patients with acute and chronic forms of paracoccidioidomycosis. , 2000, Journal of medical microbiology.

[27]  A. Sidoli,et al.  Cutting edge: identification of novel T cell epitopes in Lol p5a by computational prediction. , 1999, Journal of immunology.

[28]  F. Brown,et al.  Protection of swine from foot-and-mouth disease with one dose of an all-D retro peptide. , 1999, Vaccine.

[29]  U. Şahin,et al.  Generation of tissue-specific and promiscuous HLA ligand databases using DNA microarrays and virtual HLA class II matrices , 1999, Nature Biotechnology.

[30]  Matteo Bellone,et al.  Melanoma Cells Present a MAGE-3 Epitope to CD4+ Cytotoxic T Cells in Association with Histocompatibility Leukocyte Antigen DR11 , 1999, The Journal of experimental medicine.

[31]  E. Cunha-Neto MHC-restricted antigen presentation and recognition: constraints on gene, recombinant and peptide vaccines in humans. , 1999, Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas.

[32]  M. V. Van Regenmortel,et al.  The potential of retro-inverso peptides as synthetic vaccines. , 1998, Developments in biological standardization.

[33]  M F del Guercio,et al.  Several common HLA-DR types share largely overlapping peptide binding repertoires. , 1998, Journal of immunology.

[34]  M. Juliano,et al.  Mapping of the T-Cell Epitope in the Major 43-Kilodalton Glycoprotein of Paracoccidioides brasiliensisWhich Induces a Th-1 Response Protective against Fungal Infection in BALB/c Mice , 1998, Infection and Immunity.

[35]  G. Benard,et al.  Immunosuppression in paracoccidioidomycosis: T cell hyporesponsiveness to two Paracoccidioides brasiliensis glycoproteins that elicit strong humoral immune response. , 1997, The Journal of infectious diseases.

[36]  E. Domingo,et al.  A large-scale evaluation of peptide vaccines against foot-and-mouth disease: lack of solid protection in cattle and isolation of escape mutants , 1997, Journal of virology.

[37]  F. Sinigaglia,et al.  HLA class II peptide binding specificity and autoimmunity. , 1997, Advances in immunology.

[38]  Z. Xiang,et al.  Novel vaccine approaches. , 1996, Journal of Immunology.

[39]  Z. P. Camargo,et al.  Paracoccidioides brasiliensis-gp43 used as paracoccidioidin. , 1996, Journal of medical and veterinary mycology : bi-monthly publication of the International Society for Human and Animal Mycology.

[40]  E. van Dijk,et al.  Peptide vaccine against canine parvovirus: identification of two neutralization subsites in the N terminus of VP2 and optimization of the amino acid sequence , 1995, Journal of virology.

[41]  J. Hammer,et al.  New methods to predict MHC-binding sequences within protein antigens. , 1995, Current opinion in immunology.

[42]  H. Rammensee,et al.  Chemistry of peptides associated with MHC class I and class II molecules. , 1995, Current opinion in immunology.

[43]  J. Berzofsky,et al.  Two novel T cell epitope prediction algorithms based on MHC-binding motifs; comparison of predicted and published epitopes from Mycobacterium tuberculosis and HIV protein sequences. , 1995, Vaccine.

[44]  R. Walsky,et al.  High-affinity binding of short peptides to major histocompatibility complex class II molecules by anchor combinations. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[45]  E Brummer,et al.  Paracoccidioidomycosis: an update , 1993, Clinical Microbiology Reviews.

[46]  C. Taborda,et al.  Diagnosis of paracoccidioidomycosis by passive haemagglutination assay of antibody using a purified and specific antigen-gp43. , 1993, Journal of medical and veterinary mycology : bi-monthly publication of the International Society for Human and Animal Mycology.

[47]  O. Olerup,et al.  HLA-DR typing by PCR amplification with sequence-specific primers (PCR-SSP) in 2 hours: an alternative to serological DR typing in clinical practice including donor-recipient matching in cadaveric transplantation. , 1992, Tissue antigens.

[48]  Piero Carninci,et al.  A fast method for high-quality genomic DNA extraction from whole human blood. , 1991, BioTechniques.

[49]  L. Travassos,et al.  43-kilodalton glycoprotein from Paracoccidioides brasiliensis: immunochemical reactions with sera from patients with paracoccidioidomycosis, histoplasmosis, or Jorge Lobo's disease , 1991, Journal of clinical microbiology.

[50]  F. Sinigaglia,et al.  Selection of T cell epitopes and vaccine engineering. , 1991, Methods in enzymology.

[51]  D. King,et al.  A cleavage method which minimizes side reactions following Fmoc solid phase peptide synthesis. , 1990, International journal of peptide and protein research.

[52]  D. T. Elmore,et al.  Solid‐phase peptide synthesis: a practical approach , 1990 .

[53]  L. Travassos,et al.  Identification of antigenic polypeptides of Paracoccidioides brasiliensis by immunoblotting. , 1989, Journal of medical and veterinary mycology : bi-monthly publication of the International Society for Human and Animal Mycology.

[54]  L. Travassos,et al.  Production of Paracoccidioides brasiliensis exoantigens for immunodiffusion tests , 1988, Journal of clinical microbiology.

[55]  Pedro Romero,et al.  A synthetic vaccine protects humans against challenge with asexual blood stages of Plasmodium falciparum malaria , 1988, Nature.

[56]  L. Travassos,et al.  Exocellular components of Paracoccidioides brasiliensis: identification of a specific antigen , 1986, Infection and immunity.

[57]  R. DiMarchi,et al.  Protection of cattle against foot-and-mouth disease by a synthetic peptide. , 1986, Science.

[58]  M. Franco,et al.  Correlation between cell-mediated immunity and clinical forms of paracoccidioidomycosis. , 1985, Transactions of the Royal Society of Tropical Medicine and Hygiene.

[59]  M. Kulomaa,et al.  Production of monoclonal antibodies against avidin. , 1985, Comparative biochemistry and physiology. B, Comparative biochemistry.

[60]  R. Mendes,et al.  Serology of paracoccidioidomycosis. II. Correlation between class-specific antibodies and clinical forms of the disease. , 1984, Transactions of the Royal Society of Tropical Medicine and Hygiene.

[61]  M. Fellous,et al.  [Presence of 2 different epitopes on the human beta 2-microglobulin defined by monoclonal antibodies]. , 1983, Annales d'immunologie.

[62]  M. Shapira,et al.  Anti-influenza response achieved by immunization with a synthetic conjugate. , 1982, Proceedings of the National Academy of Sciences of the United States of America.

[63]  M. Fellous,et al.  [Production of monoclonal antibodies against HBs (author's transl)]. , 1981, Annales d'immunologie.