Hormonal aspects of breast cancer. Growth factors, drugs and stromal interactions.

[1]  M. Brennan,et al.  Peripheral lymphocyte and eosinophil counts as indicators of prognosis in primary breast cancer , 2006, Cancer.

[2]  K. Yokota,et al.  Effects of transforming growth factor-beta released from gastric carcinoma cells on the contraction of collagen-matrix gels containing fibroblasts. , 1991, Cancer research.

[3]  B. Olwin,et al.  Requirement of heparan sulfate for bFGF-mediated fibroblast growth and myoblast differentiation , 1991, Science.

[4]  J. Culouscou,et al.  Purification of a colon cancer cell growth inhibitor and its identification as an insulin-like growth factor binding protein. , 1991, Cancer research.

[5]  H. Rochefort,et al.  Estradiol down-regulates the mannose-6-phosphate/insulin-like growth factor-II receptor gene and induces cathepsin-D in breast cancer cells: a receptor saturation mechanism to increase the secretion of lysosomal proenzymes. , 1991, Molecular endocrinology.

[6]  Y. Shimizu,et al.  Lymphocyte interactions with extracellular matrix , 1991, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[7]  J. Florini,et al.  Insulin-like growth factor-I stimulates terminal myogenic differentiation by induction of myogenin gene expression. , 1991, Molecular endocrinology.

[8]  P. Schofield,et al.  Tumour suppression associated with expression of human insulin-like growth factor II. , 1991, British Journal of Cancer.

[9]  L. Israël,et al.  Fetal myofibroblast‐like cells isolated from post‐radiation fibrosis in human breast cancer , 1991, International journal of cancer.

[10]  W. McGuire,et al.  Follow-up study of HER-2/neu amplification in primary breast cancer. , 1991, Cancer research.

[11]  D. Rifkin,et al.  Cellular activation of latent transforming growth factor beta requires binding to the cation-independent mannose 6-phosphate/insulin-like growth factor type II receptor. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[12]  B. van der Burg,et al.  Role of estrogen-induced insulin-like growth factors in the proliferation of human breast cancer cells. , 1990, Cancer research.

[13]  R. Coombes,et al.  Interaction of vasopressin and oxytocin with human breast carcinoma cells. , 1990, Cancer research.

[14]  M. Johnson,et al.  Role of insulin-like growth factors and the type I insulin-like growth factor receptor in the estrogen-stimulated proliferation of human breast cancer cells. , 1990, The Journal of biological chemistry.

[15]  C. Osborne,et al.  Insulin-like growth factor binding protein secretion by breast carcinoma cell lines: correlation with estrogen receptor status. , 1990, Endocrinology.

[16]  R. Murphy,et al.  Reduction of the membrane fluidity of human breast cancer cells by tamoxifen and 17 beta-estradiol. , 1990, Journal of the National Cancer Institute.

[17]  C. Redmond,et al.  Effect of tamoxifen on serum insulinlike growth factor I levels in stage I breast cancer patients. , 1990, Journal of the National Cancer Institute.

[18]  A. Harris,et al.  Reversal of acquired resistance to adriamycin in CHO cells by tamoxifen and 4-hydroxy tamoxifen: role of drug interaction with alpha 1 acid glycoprotein. , 1990, British Journal of Cancer.

[19]  J. Nestler.  Insulin-like growth factor II is a potent inhibitor of the aromatase activity of human placental cytotrophoblasts. , 1990, Endocrinology.

[20]  R. Clarke,et al.  The process of malignant progression in human breast cancer. , 1990, Annals of oncology : official journal of the European Society for Medical Oncology.

[21]  S. Haslam,et al.  Progesterone action in normal mouse mammary gland. , 1990, Endocrinology.

[22]  R Beuscart,et al.  Prognostic significance of insulin-like growth factor 1 receptors in human breast cancer. , 1990, Cancer research.

[23]  K. Horwitz,et al.  T47DCO cells, genetically unstable and containing estrogen receptor mutations, are a model for the progression of breast cancers to hormone resistance. , 1990, Cancer research.

[24]  R. Magness,et al.  Transforming growth factor-β inhibits steroid 17α-hydroxylase cytochrome P-450 expression in ovine adrenocortical cells , 1990 .

[25]  A. Harris.  The epidermal growth factor receptor as a target for therapy. , 1990, Cancer cells.

[26]  W. Bezwoda,et al.  Effect of α-Interferon, 17β-Estradiol, and Tamoxifen on Estrogen Receptor Concentration and Cell Cycle Kinetics of MCF 7 Cells , 1990 .

[27]  C. Chiodino,et al.  Role of growth factor synthesis in the acquisition of insulin/insulin-like growth factor I independence in rat mammary carcinoma cells. , 1990, Cancer research.

[28]  K. Matsumoto,et al.  Growth stimulation by androgens, glucocorticoids or fibroblast growth factors and the blocking of the stimulated growth by antibody against basic fibroblast growth factor in protein-free culture of Shionogi carcinoma 115 cells , 1990, The Journal of Steroid Biochemistry and Molecular Biology.

[29]  M. Sporn,et al.  Anti-oestrogens induce the secretion of active transforming growth factor beta from human fetal fibroblasts. , 1990, British Journal of Cancer.

[30]  W. Schürch,et al.  Differentiation repertoire of fibroblastic cells: expression of cytoskeletal proteins as marker of phenotypic modulations. , 1990, Laboratory investigation; a journal of technical methods and pathology.

[31]  M. Gould,et al.  Reduction in the frequency of activated ras oncogenes in rat mammary carcinomas with increasing N-methyl-N-nitrosourea doses or increasing prolactin levels. , 1990, Cancer research.

[32]  J. H. Cheek,et al.  Steroid receptors in benign mastectomy tissue. , 1990, American journal of clinical pathology.

[33]  W. Daughaday.  The possible autocrine/paracrine and endocrine roles of insulin-like growth factors of human tumors. , 1990, Endocrinology.

[34]  D. Taverna,et al.  Inhibition of c-erbB-2 oncogene expression by estrogens in human breast cancer cells. , 1990, Oncogene.

[35]  I. Pastan,et al.  Transforming growth factor alpha-Pseudomonas exotoxin fusion protein prolongs survival of nude mice bearing tumor xenografts. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[36]  R. Hoover,et al.  Rising incidence of breast cancer: relationship to stage and receptor status. , 1990, Journal of the National Cancer Institute.

[37]  G. Clinton,et al.  Insulin and epidermal growth factor stimulate phosphorylation of p185HER-2 in the breast carcinoma cell line, BT474 , 1990, Molecular and Cellular Endocrinology.

[38]  K. Syrjänen,et al.  Quantitative immunohistochemical analysis of mononuclear infiltrates in breast carcinomas–correlation with tumour differentiation , 1990, The Journal of pathology.

[39]  W. Rutter,et al.  Overexpression of the human insulinlike growth factor I receptor promotes ligand-dependent neoplastic transformation , 1990, Molecular and cellular biology.

[40]  J. Hamada,et al.  Ultrastructural differences in junctional intercellular communication between highly and weakly metastatic clones derived from rat mammary carcinoma. , 1990, Cancer research.

[41]  J Lee,et al.  Perceived social support and tumor estrogen/progesterone receptor status as predictors of natural killer cell activity in breast cancer patients. , 1990, Psychosomatic medicine.

[42]  H. Takano,et al.  The direct activation of human multidrug resistance gene (MDR1) by anticancer agents. , 1989, Biochemical and biophysical research communications.

[43]  R. Dickson,et al.  Stimulation of epithelial membrane antigen expression by transforming growth factor-beta in normal and oncogene-transformed human mammary epithelial cells. , 1989, Cancer research.

[44]  S. Bates,et al.  Production of and responsiveness to transforming growth factor-beta in normal and oncogene-transformed human mammary epithelial cells. , 1989, Cancer research.

[45]  C. Osborne,et al.  Growth inhibition of human breast cancer cells in vitro with an antibody against the type I somatomedin receptor. , 1989, Cancer research.

[46]  I. Ellis,et al.  c-myc oncogene product expression and prognosis in operable breast cancer. , 1989, British Journal of Cancer.

[47]  C. Osborne,et al.  Insulin-like growth factor-II (IGF-II): a potential autocrine/paracrine growth factor for human breast cancer acting via the IGF-I receptor. , 1989, Molecular endocrinology.

[48]  C. Osborne,et al.  Blockade of the type I somatomedin receptor inhibits growth of human breast cancer cells in athymic mice. , 1989, The Journal of clinical investigation.

[49]  S. Bates,et al.  Anti-epidermal growth factor receptor antibodies inhibit the autocrine-stimulated growth of MDA-468 human breast cancer cells. , 1989, Molecular endocrinology.

[50]  D. McEachern,et al.  Growth regulation of mouse mammary tumor cells in collagen gel cultures by diffusible factors produced by normal mammary gland epithelium and stromal fibroblasts. , 1989, Cancer research.

[51]  J. Foekens,et al.  Effect of hormonal manipulation and doxorubicin administration on cell cycle kinetics of human breast cancer cells. , 1989, British Journal of Cancer.

[52]  D. Ingram,et al.  Obesity and breast disease. The role of the female sex hormones , 1989, Cancer.

[53]  C. Benz,et al.  Toremifene: pharmacologic and pharmacokinetic basis of reversing multidrug resistance. , 1989, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[54]  E. Borden,et al.  Differential ability of antiestrogens to stimulate breast cancer cell (MCF-7) growth in vivo and in vitro. , 1989, Cancer research.

[55]  J. L. Bos,et al.  ras oncogenes in human cancer: a review. , 1989, Cancer research.

[56]  Nienhuis Aw,et al.  Private and public autocrine loops in neoplastic cells. , 1989 .

[57]  C. Ballaré,et al.  DNA synthesis in estrogen receptor‐positive human breast cancer takes place preferentially in estrogen receptor‐negative cells , 1989, Cancer.

[58]  S. Keller,et al.  Inhibition of insulin degradation by insulin-like growth factors I and II in human hepatoma (HepG2) cells. , 1989, Acta endocrinologica.

[59]  R. Clarke,et al.  The inter-relationships between ovarian-independent growth, tumorigenicity, invasiveness and antioestrogen resistance in the malignant progression of human breast cancer. , 1989, The Journal of endocrinology.

[60]  P. Rabinovitch,et al.  Platelet‐derived growth factor, epidermal growth factor, and insulin‐like growth factor I regulate specific cell‐cycle parameters of human diploid fibroblasts in serum‐free culture , 1989, Journal of cellular physiology.

[61]  D. Birnbaum,et al.  Amplification of FGF-related genes in human tumors: possible involvement of HST in breast carcinomas. , 1989, Oncogene.

[62]  C. Osborne,et al.  Antagonism of chemotherapy-induced cytotoxicity for human breast cancer cells by antiestrogens. , 1989, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[63]  E. Borden,et al.  Effects of type I and II interferons on cultured human breast cells: interaction with estrogen receptors and with tamoxifen. , 1989, Cancer research.

[64]  W Godolphin,et al.  Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer. , 1989, Science.

[65]  T. Grogan,et al.  Prediction of doxorubicin resistance in vitro in myeloma, lymphoma, and breast cancer by P-glycoprotein staining. , 1989, Journal of the National Cancer Institute.

[66]  R. Murphy,et al.  Synthesis of somatostatin by breast cancer cells and their inhibition by exogenous somatostatin and sandostatin. , 1989, British Journal of Cancer.

[67]  D. O'Sullivan,et al.  Mid-G1 arrest and epidermal growth factor independence of ras-transfected mouse cells. , 1989, Cancer research.

[68]  L. Murphy,et al.  Regulation of Transforming Growth Factor α and Transforming Growth Factor β Messenger Ribonucleic Acid Abundance in T-47D, Human Breast Cancer Cells , 1989, Molecular Endocrinology.

[69]  N. Brünner,et al.  Effect on growth and cell cycle kinetics of estradiol and tamoxifen on MCF-7 human breast cancer cells grown in vitro and in nude mice. , 1989, Cancer research.

[70]  F. Leonessa,et al.  Effect of 17-beta-estradiol on doxorubicin cytotoxicity in human breast cancer cell culture. , 1989, Anticancer research.

[71]  D. Yee,et al.  Analysis of insulin-like growth factor I gene expression in malignancy: evidence for a paracrine role in human breast cancer. , 1989, Molecular endocrinology.

[72]  B. Groner,et al.  New mammary epithelial and fibroblastic cell clones in coculture form structures competent to differentiate functionally , 1989, The Journal of cell biology.

[73]  H. Rochefort,et al.  Regulation of cathepsin-D and pS2 gene expression by growth factors in MCF7 human breast cancer cells. , 1989, Molecular endocrinology.

[74]  W. Schürch,et al.  Myofibroblasts from diverse pathologic settings are heterogeneous in their content of actin isoforms and intermediate filament proteins. , 1989, Laboratory investigation; a journal of technical methods and pathology.

[75]  R. Clarke,et al.  The effects of a constitutive expression of transforming growth factor-alpha on the growth of MCF-7 human breast cancer cells in vitro and in vivo. , 1989, Molecular endocrinology.

[76]  M. Martin,et al.  Collagen synthesis and deposition in cultured fibroblasts from subcutaneous radiation-induced fibrosis. Modification as a function of cell aging. , 1989, Matrix.

[77]  I. Pastan,et al.  Expression of Multidrug Resistance Gene in Human Cancers , 1989 .

[78]  D. Yee,et al.  The insulin-like growth factor binding protein BP-25 is expressed by human breast cancer cells. , 1989, Biochemical and biophysical research communications.

[79]  Robert,et al.  Progesterone interacts with P-glycoprotein in multidrug-resistant cells and in the endometrium of gravid uterus. , 1989, The Journal of biological chemistry.

[80]  C. Benz,et al.  Incidence of activating ras oncogene mutations associated with primary and metastatic human breast cancer. , 1989, Cancer research.

[81]  A. Gown,et al.  The fibroblast-like nature of myofibroblast , 1988 .

[82]  M. Brigden,et al.  Estrogen receptor distribution in the peripheral, intermediate and central regions of breast cancers. , 1988, European journal of cancer & clinical oncology.

[83]  I. Fidler,et al.  Recognition and destruction of neoplastic cells by activated macrophages: discrimination of altered self. , 1988, Biochimica et biophysica acta.

[84]  J. Bonneterre,et al.  Insulin-like growth factor 1 receptors in human breast cancer and their relation to estradiol and progesterone receptors. , 1988, Cancer Research.

[85]  A. Howell,et al.  The relationship of body weight to response to endocrine therapy, steroid hormone receptors and survival of patients with advanced cancer of the breast. , 1988, British Journal of Cancer.

[86]  J. Henry,et al.  Measurement of oestrogen receptor mRNA levels in human breast tumours. , 1988, British Journal of Cancer.

[87]  I. Clemmensen,et al.  Stromal fibronectin staining pattern and metastasizing ability of human breast carcinoma. , 1988, Cancer research.

[88]  N. Falette,et al.  Growth inhibitory effect of 4-hydroxy-tamoxifen on the BT-20 mammary cancer cell line. , 1988, Journal of steroid biochemistry.

[89]  L. Sheffield.  Organization and growth of mammary epithelia in the mammary gland fat pad. , 1988, Journal of dairy science.

[90]  R. Shoemaker,et al.  A multidrug-resistant MCF-7 human breast cancer cell line which exhibits cross-resistance to antiestrogens and hormone-independent tumor growth in vivo. , 1988, Molecular endocrinology.

[91]  J. Hamada,et al.  Metastatic capacity and intercellular communication between normal cells and metastatic cell clones derived from a rat mammary carcinoma. , 1988, Cancer research.

[92]  P. de Cremoux,et al.  Pharmacology, molecular identification and functional characteristics of vasoactive intestinal peptide receptors in human breast cancer cells. , 1988, Cancer research.

[93]  J. Bonneterre,et al.  Presence and characterization of insulin-like growth factor 1 receptors in human benign breast disease. , 1988, European journal of cancer & clinical oncology.

[94]  David L. Page,et al.  Diagnostic Histopathology of the Breast , 1988 .

[95]  J. Foekens,et al.  Oestradiol enhances doxorubicin uptake and cytotoxicity in human breast cancer cells (MCF-7). , 1988, European journal of cancer & clinical oncology.

[96]  Constantine A. Pappas,et al.  Defective estrogen receptors in human mammary cancers: their significance in defining hormone dependence. , 1988, Journal of the National Cancer Institute.

[97]  C. Benz,et al.  Estrogen-induced post-transcriptional modulation of c-myc proto-oncogene expression in human breast cancer cells. , 1988, The Journal of biological chemistry.

[98]  Kenneth P. Karey,et al.  Differential responsiveness of human breast cancer cell lines MCF-7 and T47D to growth factors and 17 beta-estradiol. , 1988, Cancer research.

[99]  M. Black,et al.  Skin window reactivity to autologous breast cancer. An index of prognostically significant cell‐mediated immunity , 1988, Cancer.

[100]  T. Powles,et al.  Growth factor expression in normal, benign, and malignant breast tissue , 1988, British medical journal.

[101]  S. Bates,et al.  Expression of transforming growth factor alpha and its messenger ribonucleic acid in human breast cancer: its regulation by estrogen and its possible functional significance. , 1988, Molecular endocrinology.

[102]  M. Palmer,et al.  The relationship between histological grade, oestrogen receptor status, events and survival at 8 years in the NATO ('Nolvadex') trial. , 1988, British Journal of Cancer.

[103]  D. Wynford‐Thomas,et al.  Loss of dependence on IGF-1 for proliferation of human thyroid adenoma cells. , 1988, British Journal of Cancer.

[104]  W. Schürch,et al.  Smooth‐muscle differentiation in stromal cells of malignant and non‐malignant breast tissues , 1988, International journal of cancer.

[105]  P. Roholl,et al.  Expression of insulin‐like growth factor‐I and ‐II genes in human smooth muscle tumours. , 1988, The EMBO journal.

[106]  F. Rilke,et al.  Vimentin and p53 expression on epidermal growth factor receptor-positive, oestrogen receptor-negative breast carcinomas. , 1988, British Journal of Cancer.

[107]  S. Barsky,et al.  High metalloproteinase inhibitor content of human cirrhosis and its possible conference of metastasis resistance. , 1988, Journal of the National Cancer Institute.

[108]  D. Kaufman,et al.  Multihormonal regulation of insulin-like growth factor-I-related protein in MCF-7 human breast cancer cells. , 1988, Molecular endocrinology.

[109]  G. Stancel,et al.  Estrogen regulation of epidermal growth factor receptor messenger ribonucleic acid. , 1988, Molecular endocrinology.

[110]  E. Rutanen,et al.  Receptors for epidermal growth factor and insulin-like growth factor I and their relation to steroid receptors in human breast cancer. , 1988, Cancer research.

[111]  F. Bonilla,et al.  Interleukin‐2 induces cytotoxic activity in lymphocytes from regional axillary nodes of breast cancer patients , 1988, Cancer.

[112]  J. McGee,et al.  Macrophages in human breast disease: a quantitative immunohistochemical study. , 1988, British Journal of Cancer.

[113]  B. Henderson,et al.  Estrogens as a cause of human cancer: the Richard and Hinda Rosenthal Foundation award lecture. , 1988, Cancer research.

[114]  H. Horst,et al.  Characterization and frequency distribution of lymphoreticular infiltrates in axillary lymph node metastases of invasive ductal carcinoma of the breast , 1987, Cancer.

[115]  J. Underwood,et al.  Immunophenotype of the lymphoid cell infiltrates in breast carcinomas of low oestrogen receptor content. , 1987, British Journal of Cancer.

[116]  S. Jacobs,et al.  An antibody to the receptor for insulin-like growth factor I inhibits the growth of MCF-7 cells in tissue culture. , 1987, Biochemical and biophysical research communications.

[117]  P. Darbre,et al.  Progression to steroid insensitivity can occur irrespective of the presence of functional steroid receptors , 1987, Cell.

[118]  O. Petersen,et al.  Frequency and distribution of estrogen receptor-positive cells in normal, nonlactating human breast tissue. , 1987, Cancer research.

[119]  A. Schor,et al.  Clonal heterogeneity in fibroblast phenotype: Implications for the control of epithelial‐mesenchymal interactions , 1987, BioEssays : news and reviews in molecular, cellular and developmental biology.

[120]  A. Nicolin,et al.  Chemotherapy with estrogenic recruitment and surgery in locally advanced breast cancer: Clinical and cytokinetic results , 1987, International journal of cancer.

[121]  S. Ethier,et al.  Importance of extended growth potential and growth factor independence on in vivo neoplastic potential of primary rat mammary carcinoma cells. , 1987, Cancer research.

[122]  H. Hansson,et al.  Dynamic changes in insulin-like growth factor I immunoreactivity correlate to repair events in rat ear after freeze-thaw injury. , 1987, Experimental and molecular pathology.

[123]  A Ahmed,et al.  Stromal changes in invasive breast carcinoma: An ultrastructural study , 1987, The Journal of pathology.

[124]  H. Rochefort,et al.  Antiestrogens inhibit the mitogenic effect of growth factors on breast cancer cells in the total absence of estrogens. , 1987, Biochemical and biophysical research communications.

[125]  N. Davidson,et al.  Synthesis and secretion of platelet-derived growth factor by human breast cancer cell lines. , 1987, Proceedings of the National Academy of Sciences of the United States of America.

[126]  R. Sutherland,et al.  Epidermal growth factor partially reverses the inhibitory effects of antiestrogens on T 47D human breast cancer cell growth. , 1987, Biochemical and biophysical research communications.

[127]  T. Riss,et al.  Growth and continuous passage of COMMA-D mouse mammary epithelial cells in hormonally defined serum-free medium. , 1987, Cancer research.

[128]  S. Weiss,et al.  Myofibroblastoma of the Breast: Sixteen Cases of a Distinctive Benign Mesenchymal Tumor , 1987, The American journal of surgical pathology.

[129]  C. Heldin,et al.  Frequent expression of growth factors for mesenchymal cells in human mammary carcinoma cell lines. , 1987, Cancer research.

[130]  I. Pastan,et al.  Activity of a recombinant fusion protein between transforming growth factor type alpha and Pseudomonas toxin. , 1987, Proceedings of the National Academy of Sciences of the United States of America.

[131]  J. Crissman,et al.  In situ quantitation of inflammatory mononuclear cells in ductal infiltrating breast carcinoma. Relation to prognostic parameters. , 1987, The American journal of pathology.

[132]  J. Massagué.  The TGF-β family of growth and differentiation factors , 1987, Cell.

[133]  B. Roos,et al.  Expression of insulin‐like growth factor‐I and ‐II genes in rat medullary thyroid carcinoma , 1987, FEBS letters.

[134]  J. Berry,et al.  Modulation of natural killer cell activity by tamoxifen in stage I post-menopausal breast cancer. , 1987, European journal of cancer & clinical oncology.

[135]  I. Screpanti,et al.  Estrogen and antiestrogen modulation of the levels of mouse natural killer activity and large granular lymphocytes. , 1987, Cellular immunology.

[136]  D. Clemmons,et al.  An insulin-like growth factor (IGF) binding protein enhances the biologic response to IGF-I. , 1987, Proceedings of the National Academy of Sciences of the United States of America.

[137]  M. Metzler.  Metabolic activation of xenobiotic stilbene estrogens. , 1987, Federation proceedings.

[138]  J. Folkman,et al.  Endothelial cell-derived basic fibroblast growth factor: synthesis and deposition into subendothelial extracellular matrix. , 1987, Proceedings of the National Academy of Sciences of the United States of America.

[139]  R. Murphy,et al.  The response of human breast cancer cells to glucagon , 1987 .

[140]  S. Barsky,et al.  Increased invasion and spontaneous metastasis of BL6 melanoma with inhibition of the desmoplastic response in C57 BL/6 mice. , 1987, Cancer research.

[141]  J. Foekens,et al.  Direct inhibitory effects of somatostatin (analogues) on the growth of human breast cancer cells. , 1987, Cancer research.

[142]  E. Gelmann,et al.  Epidermal growth factor receptor gene expression in estrogen receptor-positive and negative human breast cancer cell lines. , 1987, Molecular endocrinology.

[143]  C. Beattie,et al.  Estrogen receptor in dissociated and cultured human breast fibroadenoma epithelial cells. , 1987, Cancer letters.

[144]  M. Lynch,et al.  Recombinant human interferon alpha increases oestrogen receptor expression in human breast cancer cells (ZR-75-1) and sensitizes them to the anti-proliferative effects of tamoxifen. , 1987, British Journal of Cancer.

[145]  R. Mansel,et al.  Mitogenicity of human fibroblasts in vivo for human breast cancer cells , 1987, The British journal of surgery.

[146]  B. Groner,et al.  Ha-ras oncogene expression directed by a milk protein gene promoter: tissue specificity, hormonal regulation, and tumor induction in transgenic mice. , 1987, Proceedings of the National Academy of Sciences of the United States of America.

[147]  R. Derynck,et al.  Evidence that transforming growth factor-β is a hormonally regulated negative growth factor in human breast cancer cells , 1987, Cell.

[148]  P. Wingo,et al.  Oral-contraceptive use and the risk of breast cancer. The Cancer and Steroid Hormone Study of the Centers for Disease Control and the National Institute of Child Health and Human Development. , 1987, The New England journal of medicine.

[149]  T. Shows,et al.  Enhanced levels of insulin-like growth factor messenger RNA in human colon carcinomas and liposarcomas. , 1986, Cancer research.

[150]  J. Foekens,et al.  Combined effects of buserelin, estradiol and tamoxifen on the growth of MCF-7 human breast cancer cells in vitro. , 1986, Biochemical and biophysical research communications.

[151]  D. Kaufman,et al.  Secretion of an insulin-like growth factor-I-related protein by human breast cancer cells. , 1986, Cancer research.

[152]  N. Brünner,et al.  Serum steroid levels in intact and endocrine ablated BALB/c nude mice and their intact littermates. , 1986, Journal of steroid biochemistry.

[153]  R. Dickson,et al.  Estrogen-induced factors of breast cancer cells partially replace estrogen to promote tumor growth. , 1986, Science.

[154]  P. Nowell.  Mechanisms of tumor progression. , 1986, Cancer research.

[155]  A. Howell,et al.  Intralobular stromal fibroblasts in the resting human mammary gland: ultrastructural properties and intercellular relationships. , 1986, Journal of submicroscopic cytology.

[156]  A. Miller,et al.  UICC multidisciplinary project on breast cancer: The epidemiology, aetiology and prevention of breast cancer , 1986, International journal of cancer.

[157]  S. Lamberts,et al.  Long-term treatment of acromegaly with the somatostatin analogue SMS 201-995. , 1985, The New England journal of medicine.

[158]  D. Appleton,et al.  Presence of epidermal growth factor receptor as an indicator of poor prognosis in patients with breast cancer. , 1985, Journal of clinical pathology.

[159]  A. Nicolin,et al.  Chemotherapy following estrogen-induced expansion of the growth fraction of human breast cancer. , 1985, Cancer research.

[160]  J. Scott,et al.  Insulin-like growth factor-II gene expression in Wilms' tumour and embryonic tissues , 1985, Nature.

[161]  M. Eccles,et al.  Expression of insulin-like growth factor-II transcripts in Wilms' tumour , 1985, Nature.

[162]  K. Eidne,et al.  Gonadotropin-releasing hormone binding sites in human breast carcinoma. , 1985, Science.

[163]  R. Murphy,et al.  The effect of the rate of cell proliferation on the synthesis of methotrexate poly-gamma-glutamates in two human breast cancer cell lines. , 1985, Biochemical pharmacology.

[164]  V. Mukku,et al.  Regulation of epidermal growth factor receptor by estrogen. , 1985, The Journal of biological chemistry.

[165]  E. Bauer,et al.  Stimulation of in vitro human skin collagenase expression by platelet-derived growth factor. , 1985, Proceedings of the National Academy of Sciences of the United States of America.

[166]  D. Lowy,et al.  Transfection of v-rasH DNA into MCF-7 human breast cancer cells bypasses dependence on estrogen for tumorigenicity. , 1985, Science.

[167]  S. Haslam,et al.  Estrogen responsiveness of normal mouse mammary cells in primary cell culture: association of mammary fibroblasts with estrogenic regulation of progesterone receptors. , 1985, Endocrinology.

[168]  D. Stucki,et al.  Unaltered immunocompetence in patients with nondisseminated breast cancer at the time of diagnosis , 1985, Cancer.

[169]  G. Goldenberg,et al.  Anatagonism of the cytocidal activity and uptake of melphalan by tamoxifen in human breast cancer cells in vitro , 1985 .

[170]  R. Murphy,et al.  Oestrogen receptor status and the response of human breast cancer cell lines to a combination of methotrexate and 17-beta oestradiol. , 1985, British Journal of Cancer.

[171]  R. Shiu,et al.  Receptor binding and growth-promoting activity of insulin-like growth factors in human breast cancer cells (T-47D) in culture. , 1984, Cancer research.

[172]  Y. Collan,et al.  Estrogen and progesterone receptors in breast cancer: relationships to tumour histopathology and survival of patients. , 1984, Anticancer research.

[173]  Z. Fuks,et al.  Reversal of acquired resistance to doxorubicin in P388 murine leukemia cells by tamoxifen and other triparanol analogues. , 1984, Cancer research.

[174]  G. Heppner,et al.  Mutagenic activity of tumor-associated macrophages in Salmonella typhimurium strains TA98 and TA 100. , 1984, Cancer research.

[175]  P. Leder,et al.  Spontaneous mammary adenocarcinomas in transgenic mice that carry and express MTV/myc fusion genes , 1984, Cell.

[176]  T. Triche,et al.  Isolation and characterization of an estrogen-inhibited variant derived from the MCF-7 breast cancer cell line. , 1984, Cancer research.

[177]  J. Campisi,et al.  Post-transcriptional control of the onset of DNA synthesis by an insulin-like growth factor , 1984, Molecular and cellular biology.

[178]  Richie Jp.  Abrogation of hematogenous metastases in a murine model by natural killer cells. , 1984 .

[179]  J. Wittliff,et al.  Epidermal growth factor binding by breast tumor biopsies and relationship to estrogen receptor and progestin receptor levels. , 1984, Cancer research.

[180]  C. Osborne,et al.  Perturbation by insulin of human breast cancer cell cycle kinetics. , 1984, Cancer research.

[181]  S. Ghali,et al.  In vitro stimulation of human NK activity by an estrogen antagonist (tamoxifen) , 1984, European journal of cancer & clinical oncology.

[182]  O. Stutman.  Natural antitumor resistance in immune-deficient mice. , 1984, Experimental cell biology.

[183]  Gary R. Grotendorst,et al.  Desmoplastic breast carcinoma as a source of human myofibroblasts. , 1984, The American journal of pathology.

[184]  R. Furlanetto,et al.  Somatomedin-C receptors and growth effects in human breast cells maintained in long-term tissue culture. , 1984, Cancer research.

[185]  J. V. Vande Berg,et al.  Growth Dynamics of Cultured Myofibroblasts from Human Breast Cancer and Nonmalignant Contracting Tissues , 1984, Plastic and reconstructive surgery.

[186]  J. Emerman,et al.  Effects of endocrine regulation of growth of a mouse mammary tumor on its sensitivity to chemotherapy. , 1984, Cancer research.

[187]  D.B. Thomas.  Do hormones cause breast cancer? , 1984, Cancer.

[188]  J. Wittliff.  Steroid‐hormone receptors in breast cancer , 1984, Cancer.

[189]  S. Alberti,et al.  Effect of hydrocortisone on the macrophage content, growth and metastasis of transplanted murine tumors , 1984, International journal of cancer.

[190]  M. Barbacid,et al.  Induction of mammary carcinomas in rats by nitroso-methylurea involves malignant activation of H-ras-1 locus by single point mutations , 1983, Nature.

[191]  J. Enami,et al.  Growth of normal and neoplastic mouse mammary epithelial cells in primary culture: stimulation by conditioned medium from mouse mammary fibroblasts. , 1983, Gan.

[192]  D. Duval,et al.  Non-genomic effects of steroids. Interactions of steroid molecules with membrane structures and functions. , 1983, Biochimica et biophysica acta.

[193]  J. Barrett,et al.  Aneuploidy induction and cell transformation by diethylstilbestrol: a possible chromosomal mechanism in carcinogenesis. , 1983, Cancer research.

[194]  P. Briand.  Hormone-dependent mammary tumors in mice and rats as a model for human breast cancer (review). , 1983, Anticancer research.

[195]  D. Medina,et al.  Effects of combination estrogen:cyclophosphamide treatment on the growth of the MXT transplantable mammary tumor in the mouse. , 1983, Cancer research.

[196]  D. G. Hoel,et al.  ‘Hormonal’ risk factors, ‘breast tissue age’ and the age-incidence of breast cancer , 1983, Nature.

[197]  M. Akhtar,et al.  Secretory carcinoma of the breast in adults. Light and electron microscopic study of three cases with review of the literature , 1983, Cancer.

[198]  D. Clemmons,et al.  Variables controlling somatomedin production by cultured human fibroblasts , 1983, Journal of cellular physiology.

[199]  S. O’Brien,et al.  Clonal variation of MCF-7 breast cancer cells in vitro and in athymic nude mice. , 1983, Cancer research.

[200]  C. Mcgrath.  Augmentation of the response of normal mammary epithelial cells to estradiol by mammary stroma. , 1983, Cancer research.

[201]  M. Schneider,et al.  Enhancement of tumor metastasis and suppression of natural killer cell activity by beta-estradiol treatment. , 1983, Journal of immunology.

[202]  Wheelock Ef,et al.  Biology of disease. Endogenous control of the neoplastic process. , 1983 .

[203]  F. Perri,et al.  EPIDERMAL GROWTH FACTOR, SOMATOSTATIN, AND PSORIASIS , 1983, The Lancet.

[204]  Gary R. Grotendorst,et al.  Increased content of Type V Collagen in desmoplasia of human breast carcinoma. , 1982, The American journal of pathology.

[205]  A. Manni,et al.  Role of estrogen and prolactin in the growth and receptor levels of N-nitrosomethylurea-induced rat mammary tumors. , 1982, Cancer research.

[206]  H. Spector,et al.  Quantitative estrogen receptor values and growth of carcinoma of the breast before surgical intervention , 1982, Cancer.

[207]  R. Wiltrout,et al.  Role of NK cells in the control of metastatic spread and growth of tumor cells in mice , 1982, International journal of cancer.

[208]  S. Vuk-Pavlović,et al.  SOMATOSTATIN‐REDUCED PROLIFERATION OF MURINE APLASTIC CARCINOMA CONDITIONED TO DIABETES , 1982, International journal of cancer.

[209]  M. Lippman,et al.  Hormonal regulation of net DNA synthesis in MCF-7 human breast cancer cells in tissue culture. , 1982, Cancer research.

[210]  R. Nicholson,et al.  Use of analogues of luteinizing hormone-releasing hormone for the treatment of cancer. , 1982, Journal of reproduction and fertility.

[211]  C. Welsch,et al.  Estrogen induced growth of human breast cancer cells (MCF-7) in athymic nude mice is enhanced by secretions from a transplantable pituitary tumor. , 1981, Cancer letters.

[212]  T. G. Muldoon.  Interplay between estradiol and prolactin in the regulation of steroid hormone receptor levels, nature, and functionality in normal mouse mammary tissue. , 1981, Endocrinology.

[213]  T. Anderson,et al.  Morphological evaluation of cell turnover in relation to the menstrual cycle in the "resting" human breast. , 1981, British Journal of Cancer.

[214]  F. Grantham,et al.  Role of hormones in the growth and regression of human breast cancer cells (MCF-7) transplanted into athymic nude mice. , 1981, Journal of the National Cancer Institute.

[215]  P. Romero,et al.  Adherent cells (macrophages?) in tumor-bearing mice suppress MLC responses. , 1981, Cellular immunology.

[216]  P. Tartter,et al.  Cholesterol and obesity as prognostic factors in breast cancer , 1981, Cancer.

[217]  S. Haslam,et al.  Relative distribution of estrogen and progesterone receptors among the epithelial, adipose, and connective tissue components of the normal mammary gland. , 1981, Endocrinology.

[218]  F. J. Volenec,et al.  Immunologic responsiveness of the breast cancer patient , 1980, Cancer.

[219]  H. Rochefort,et al.  A secreted glycoprotein induced by estrogen in human breast cancer cell lines , 1980, Cell.

[220]  P. Allavena,et al.  Natural killer activity of lymphoid cells isolated from human ascitic ovarian tumors , 1980, International journal of cancer.

[221]  J. Talmadge,et al.  Role of NK cells in tumour growth and metastasis in beige mice , 1980, Nature.

[222]  S. Ben-Efraim,et al.  Immunocompetence, immunosuppression, and human breast cancer. III. Prognostic significance of initial level of immunocompetence in early and advanced disease , 1980, Cancer.

[223]  K. Rothman,et al.  The epidemic of endometrial cancer: a commentary. , 1979, American journal of public health.

[224]  M. Moore,et al.  Suppressor cell activity of lymphocytes infiltrating human lung and breast tumours , 1979, International journal of cancer.

[225]  G. Sato,et al.  Growth of a human mammary tumour cell line in a serum-free medium , 1979, Nature.

[226]  G. Thorbecke,et al.  Immunoglobulin isotypes in plasma cells of normal and athymic mice. , 1979, Cellular immunology.

[227]  G. Murphy,et al.  Survey of primary liver tumors and oral contraceptive use. , 1979, Journal of toxicology and environmental health.

[228]  W. Seaman,et al.  beta-Estradiol reduces natural killer cells in mice. , 1978, Journal of immunology.

[229]  L. Engel,et al.  Human breast carcinoma cells in continuous culture: a review. , 1978, Cancer research.

[230]  R. Weichselbaum,et al.  Proliferation Kinetics of a Human Breast Cancer Line in Vitro following Treatment with 17β-Estradiol and 1-β-d-Arabinofuranosylcytosine , 1978 .

[231]  G. Todaro,et al.  Growth factors from murine sarcoma virus-transformed cells. , 1978, Proceedings of the National Academy of Sciences of the United States of America.

[232]  M. R. Warner.  Effect of perinatal oestrogen on the pretreatment required for mouse mammary lobular formation in vitro. , 1978, The Journal of endocrinology.

[233]  J. Meyer,et al.  Low incidence of estrogen receptor in breast carcinomas with rapid rates of cellular replication , 1977, Cancer.

[234]  M. Lippman,et al.  The effects of estrogens and antiestrogens on hormone-responsive human breast cancer in long-term tissue culture. , 1976, Cancer research.

[235]  P. Nowell.  The clonal evolution of tumor cell populations. , 1976, Science.

[236]  M. Lippman,et al.  Interactions of antiestrogens with human breast cancer in long-term tissue culture. , 1976, Cancer treatment reports.

[237]  P. Comoglio,et al.  Induction of resistance or enhancement to a transplantable murine plasmacytoma by transfer of non-immune leucocytes. , 1976, British Journal of Cancer.

[238]  J. Remington,et al.  Control of Carcinogenesis: A Possible Role for the Activated Macrophage , 1972, Science.

[239]  A. Herbst,et al.  Adenocarcinoma of the vagina. Association of maternal stilbestrol therapy with tumor appearance in young women. , 1971, The New England journal of medicine.

[240]  L. Ozzello.  Epithelial‐stromal junction of normal and dysplastic mammary glands , 1970, Cancer.

[241]  S. Bates,et al.  Expression of the transforming growth factor-alpha/epidermal growth factor receptor pathway in normal human breast epithelial cells. , 1990, Endocrinology.

[242]  G. Bonadonna.  Does chemotherapy fulfill its expectations in cancer treatment? , 1990, Annals of oncology : official journal of the European Society for Medical Oncology.

[243]  T. Hsu,et al.  Fibroblast-mediated acceleration of human epithelial tumor growth in vivo. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[244]  C R King,et al.  Pathologic findings from the National Surgical Adjuvant Breast and Bowel Project: prognostic significance of erbB-2 protein overexpression in primary breast cancer. , 1990, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[245]  T. Fleming,et al.  Autocrine interaction between TGF alpha and the EGF-receptor: quantitative requirements for induction of the malignant phenotype. , 1989, Oncogene.

[246]  L. Yee,et al.  Human breast carcinoma cell levels of MDR-1 (P-glycoprotein) transcripts correlate in vivo inversely and reciprocally with tumor progesterone receptor content. , 1989, Cancer communications.

[247]  S. Bates,et al.  Transforming Growth Factor α Production and Epidermal Growth Factor Receptor Expression in Normal and Oncogene Transformed Human Mammary Epithelial Cells , 1989 .

[248]  D. Fabbro,et al.  In vitro cultures of epithelial cells from healthy breast tissues and cells from breast carcinomas. , 1989, Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer.

[249]  A. van den Hooff,et al.  Stromal involvement in malignant growth. , 1988 .

[250]  M. Mesiti,et al.  Influence of sera from patients affected by neoplasia on some human macrophage functions. , 1988, Cancer detection and prevention.

[251]  O. Contreras Ortiz,et al.  Immunological changes in human breast cancer. , 1988, European journal of gynaecological oncology.

[252]  T. K. Hunt,et al.  Somatomedins: do they play a pivotal role in wound healing? , 1988, Progress in clinical and biological research.

[253]  S. Iacobelli,et al.  Growth inhibitory effect of LH-RH analogs on human breast cancer cells. , 1988, Anticancer research.

[254]  Emerman Jt.  Effects of hormonal modulation on cytotoxicity of chemotherapeutic agents in mouse mammary tumor cell cultures. , 1988 .

[255]  I. Fidler.  Eradication of cancer metastasis by tumoricidal macrophages. , 1988, Advances in experimental medicine and biology.

[256]  M. Kanje,et al.  Tissue repair and IGF-I. , 1988, Acta paediatrica Scandinavica. Supplement.

[257]  D. Greenberg,et al.  Calcium channel antagonist properties of the antineoplastic antiestrogen tamoxifen in the PC12 neurosecretory cell line. , 1987, Cancer research.

[258]  Samaan Na,et al.  Enhancement of hormonal synchronization and 5-fluorouracil cytotoxicity in breast cancer cells by low concentration of thymidine. , 1987 .

[259]  M J Bissell,et al.  Influence of a reconstituted basement membrane and its components on casein gene expression and secretion in mouse mammary epithelial cells. , 1987, Proceedings of the National Academy of Sciences of the United States of America.

[260]  L. Skoog,et al.  Estrogen receptor levels and survival of breast cancer patients. A study on patients participating in randomized trials of adjuvant therapy. , 1987, Acta oncologica.

[261]  J. Florini,et al.  The type II insulin-like growth factor (IGF) receptor has low affinity for IGF-I analogs: pleiotypic actions of IGFs on myoblasts are apparently mediated by the type I receptor. , 1987, Endocrinology.

[262]  F. V. Defeudis,et al.  Studies on somatostatin analogues might lead to new therapies for certain types of cancer , 1986 .

[263]  G. Hortobagyi,et al.  Use of growth-stimulatory hormones to improve the in vitro therapeutic index of doxorubicin for human breast tumors. , 1986, Cancer research.

[264]  A. Nicolin,et al.  Cytokinetic parameters of locally advanced human breast cancer treated with diethylstilbestrol and chemotherapy. , 1986, Basic and applied histochemistry.

[265]  H. Bradlow,et al.  Oestradiol 16 alpha-hydroxylase: a risk marker for breast cancer. , 1986, Cancer surveys.

[266]  G. Bousfield,et al.  Hormonal carcinogenesis: separation of estrogenicity from carcinogenicity. , 1986, Chemico-biological interactions.

[267]  E. Gelmann,et al.  Autocrine and paracrine growth regulation of human breast cancer. , 1986 .

[268]  S. Haslam.  Mammary fibroblast influence on normal mouse mammary epithelial cell responses to estrogen in vitro. , 1986, Cancer research.

[269]  M. Tan,et al.  Assessment of host immune response in breast cancer patients. , 1986, Cancer detection and prevention.

[270]  K. Cantell,et al.  Additive and synergistic effects of a novel antiestrogen, toremifene (Fc-1157a), and human interferons on estrogen responsive MCF-7 cells in vitro. , 1985, Medical biology.

[271]  B. H. Petersen,et al.  Estradiol induced alterations of the immune system--I. Enhancement of IgM production. , 1985, International journal of immunopharmacology.

[272]  R. Rosso,et al.  Rationale for combining chemotherapy and hormonal therapy in breast cancer. , 1985, Journal of steroid biochemistry.

[273]  M. Lippman,et al.  A randomized attempt to increase the efficacy of cytotoxic chemotherapy in metastatic breast cancer by hormonal synchronization. , 1984, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[274]  J. Fishman.  Aromatic hydroxylation of estrogens. , 1983, Annual review of physiology.

[275]  R. Murphy,et al.  Reduction of the anti-metabolic and anti-proliferative effects of methotrexate by 17 beta-oestradiol in a human breast carcinoma cell line, MDA-MB-436. , 1983, European journal of cancer & clinical oncology.

[276]  M. Hanna,et al.  Mechanisms of macrophage-mediated tumor cytolysis. , 1982, Advances in experimental medicine and biology.

[277]  O. Alabaster,et al.  Metabolic modification by insulin enhances methotrexate cytotoxicity in MCF-7 human breast cancer cells. , 1981, European journal of cancer & clinical oncology.

[278]  W. Seaman,et al.  THE EFFECT OF 17β-ESTRADIOL ON NATURAL KILLING IN THE MOUSE , 1980 .

[279]  G. Bradford,et al.  Plasma luteinizing hormone, follicle-stimulating hormone and prolactin during pregnancy in the mouse. , 1974, Endocrinology.

[280]  W. McGuire.  Estrogen receptors in human breast cancer. , 1973, The Journal of clinical investigation.

[281]  A. Raynaud.  Observations sur les modifications, provoquees par les hormones oestrogènes, du mode de développement des mamelons des foetus de souris. , 1955 .

[282]  G. Snell.  Biology of the Laboratory Blouse. , 1941 .