CD36+ cancer-associated fibroblasts provide immunosuppressive microenvironment for hepatocellular carcinoma via secretion of macrophage migration inhibitory factor

[1]  Laisheng Li,et al.  USP12 positively regulates M‐MDSC function to inhibit antitumour immunity through deubiquitinating and stabilizing p65 , 2022, Immunology.

[2]  Weidong Wei,et al.  Landscape of cancer-associated fibroblasts identifies the secreted biglycan as a protumor and immunosuppressive factor in triple-negative breast cancer , 2022, Oncoimmunology.

[3]  V. Dudeja,et al.  Cancer-Associated Fibroblasts in Pancreatic Ductal Adenocarcinoma: An Update on Heterogeneity and Therapeutic Targeting , 2021, International journal of molecular sciences.

[4]  D. Rader,et al.  TRIB1 regulates LDL metabolism through CEBPα-mediated effects on the LDL receptor in hepatocytes. , 2021, The Journal of clinical investigation.

[5]  G. Middleton,et al.  TGF-β orchestrates the phenotype and function of monocytic myeloid-derived suppressor cells in colorectal cancer , 2021, Cancer Immunology, Immunotherapy.

[6]  M. Mino‐Kenudson,et al.  Three subtypes of lung cancer fibroblasts define distinct therapeutic paradigms. , 2021, Cancer cell.

[7]  Yongjin P. Park.  Faculty Opinions recommendation of SCENIC: single-cell regulatory network inference and clustering. , 2021, Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature.

[8]  Yuli Lin,et al.  CAFs shape myeloid‐derived suppressor cells to promote stemness of intrahepatic cholangiocarcinoma through 5‐lipoxygenase , 2021, Hepatology.

[9]  Jonathan M. Hernandez,et al.  Single-cell atlas of tumor cell evolution in response to therapy in hepatocellular carcinoma and intrahepatic cholangiocarcinoma. , 2021, Journal of hepatology.

[10]  R. Schwabe,et al.  Promotion of cholangiocarcinoma growth by diverse cancer-associated fibroblast subpopulations. , 2021, Cancer cell.

[11]  Yaojun Zhang,et al.  Cancer‐Associated Fibroblast‐Mediated Cellular Crosstalk Supports Hepatocellular Carcinoma Progression , 2021, Hepatology.

[12]  D. Zheng,et al.  Molecular Features of Cancer-associated Fibroblast Subtypes and their Implication on Cancer Pathogenesis, Prognosis, and Immunotherapy Resistance , 2021, Clinical Cancer Research.

[13]  M. Rehli,et al.  The IKZF1–IRF4/IRF5 Axis Controls Polarization of Myeloma-Associated Macrophages , 2021, Cancer Immunology Research.

[14]  Lihua Zhang,et al.  Inference and analysis of cell-cell communication using CellChat , 2020, Nature Communications.

[15]  D. Xing,et al.  The Trends of Single-Cell Analysis: A Global Study , 2020, BioMed research international.

[16]  A. Zhu,et al.  Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline. , 2020, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[17]  Justine Jia Wen Seow,et al.  Onco-fetal Reprogramming of Endothelial Cells Drives Immunosuppressive Macrophages in Hepatocellular Carcinoma , 2020, Cell.

[18]  Meng Li,et al.  Cancer-Associated Fibroblasts Provide a Stromal Niche for Liver Cancer Organoids That Confers Trophic Effects and Therapy Resistance , 2020, Cellular and molecular gastroenterology and hepatology.

[19]  H. Woo,et al.  scTyper: a comprehensive pipeline for the cell typing analysis of single-cell RNA-seq data , 2020, BMC Bioinformatics.

[20]  Yuan Zhang,et al.  Single cell transcriptomic architecture and intercellular crosstalk of human intrahepatic cholangiocarcinoma. , 2020, Journal of hepatology.

[21]  H. Wanibuchi,et al.  Myeloid-derived suppressor cells are essential partners for immune checkpoint inhibitors in the treatment of cisplatin-resistant bladder cancer. , 2020, Cancer letters.

[22]  J. Shang,et al.  Transcription factor RUNX3 promotes CD8+ T cell recruitment by CCL3 and CCL20 in lung adenocarcinoma immune microenvironment , 2020, Journal of cellular biochemistry.

[23]  M. Ho,et al.  Reliability of a Single-region Sample to evaluate Immune Tumor Microenvironment in Hepatocellular Carcinoma. , 2020, Journal of hepatology.

[24]  Li Ding,et al.  Integrated Proteogenomic Characterization of HBV-Related Hepatocellular Carcinoma , 2019, Cell.

[25]  Jian Luo,et al.  C/EBPδ-Slug-Lox1 axis promotes metastasis of lung adenocarcinoma via oxLDL uptake , 2019, Oncogene.

[26]  Keqiu Jiang,et al.  Heterogeneity of cancer-associated fibroblasts and roles in the progression, prognosis, and therapy of hepatocellular carcinoma , 2019, Journal of Hematology & Oncology.

[27]  R. Bernards,et al.  Inducing and exploiting vulnerabilities for the treatment of liver cancer , 2019, Nature.

[28]  P. Robson,et al.  Cross-species single-cell analysis of pancreatic ductal adenocarcinoma reveals antigen-presenting cancer-associated fibroblasts. , 2019, Cancer discovery.

[29]  M. Merad,et al.  β-catenin activation promotes immune escape and resistance to anti-PD-1 therapy in hepatocellular carcinoma. , 2019, Cancer discovery.

[30]  Ash A. Alizadeh,et al.  Determining cell-type abundance and expression from bulk tissues with digital cytometry , 2019, Nature Biotechnology.

[31]  T. Greten,et al.  Targeting the crosstalk between cytokine-induced killer cells and myeloid-derived suppressor cells in hepatocellular carcinoma. , 2019, Journal of hepatology.

[32]  R. Coomaraswamy,et al.  Global Study , 2018, The Oxford Handbook of Women, Peace, and Security.

[33]  Paul Hoffman,et al.  Integrating single-cell transcriptomic data across different conditions, technologies, and species , 2018, Nature Biotechnology.

[34]  T. Hughes,et al.  The Human Transcription Factors , 2018, Cell.

[35]  Amanda R. Campbell,et al.  Nitric Oxide Production by Myeloid-Derived Suppressor Cells Plays a Role in Impairing Fc Receptor–Mediated Natural Killer Cell Function , 2018, Clinical Cancer Research.

[36]  Hannah A. Pliner,et al.  Reversed graph embedding resolves complex single-cell trajectories , 2017, Nature Methods.

[37]  J. Aerts,et al.  SCENIC: Single-cell regulatory network inference and clustering , 2017, Nature Methods.

[38]  J. Shyy,et al.  Context-Dependent Role of Oxidized Lipids and Lipoproteins in Inflammation , 2017, Trends in Endocrinology & Metabolism.

[39]  R. Schwabe,et al.  The Role of Cancer-Associated Fibroblasts and Fibrosis in Liver Cancer. , 2017, Annual review of pathology.

[40]  Yuli Lin,et al.  FAP Promotes Immunosuppression by Cancer-Associated Fibroblasts in the Tumor Microenvironment via STAT3-CCL2 Signaling. , 2016, Cancer research.

[41]  J. Sévigny,et al.  Characterization of hepatic stellate cells, portal fibroblasts, and mesothelial cells in normal and fibrotic livers. , 2016, Journal of hepatology.

[42]  R. Satija,et al.  Single-cell analysis reveals key roles for Bcl11a in regulating stem cell fate decisions , 2015, Genome Biology.

[43]  Christopher J. Kane,et al.  Immunosuppressive plasma cells impede T cell-dependent immunogenic chemotherapy , 2015, Nature.

[44]  C. Sung,et al.  Twist1 is a key regulator of cancer-associated fibroblasts. , 2015, Cancer research.

[45]  Wen-Chang Chang,et al.  Glycogen synthase kinase-3β–mediated CCAAT/enhancer-binding protein delta phosphorylation in astrocytes promot es migration and activation of microglia/macrophages , 2014, Neurobiology of Aging.

[46]  J. Cross,et al.  MIF: metastasis/MDSC-inducing factor? , 2013, Oncoimmunology.

[47]  D. Templeton,et al.  Macrophage Migration Inhibitory Factor Promotes Tumor Growth and Metastasis by Inducing Myeloid-Derived Suppressor Cells in the Tumor Microenvironment , 2012, The Journal of Immunology.

[48]  P. Heinrich,et al.  Hepatic acute phase proteins--regulation by IL-6- and IL-1-type cytokines involving STAT3 and its crosstalk with NF-κB-dependent signaling. , 2012, European journal of cell biology.

[49]  Linh Vong,et al.  MEF2C ablation in endothelial cells reduces retinal vessel loss and suppresses pathologic retinal neovascularization in oxygen-induced retinopathy. , 2012, The American journal of pathology.

[50]  Peter F. Johnson,et al.  C5a-regulated CCAAT/Enhancer-binding Proteins β and δ Are Essential in Fcγ Receptor-mediated Inflammatory Cytokine and Chemokine Production in Macrophages* , 2011, The Journal of Biological Chemistry.

[51]  S. Powers,et al.  p38 MAPK links oxidative stress to autophagy-related gene expression in cachectic muscle wasting. , 2010, American journal of physiology. Cell physiology.

[52]  S. Kashyap,et al.  Lipid‐induced Insulin Resistance Is Associated With Increased Monocyte Expression of Scavenger Receptor CD36 and Internalization of Oxidized LDL , 2009, Obesity.

[53]  P. Guermonprez,et al.  Selection of an Antibody Library Identifies a Pathway to Induce Immunity by Targeting CD36 on Steady-State CD8α+ Dendritic Cells1 , 2008, The Journal of Immunology.

[54]  Weidong Zhang,et al.  Expression of hepatitis B virus proteins in transgenic mice alters lipid metabolism and induces oxidative stress in the liver. , 2008, Journal of hepatology.

[55]  E. Nishida,et al.  The C. elegans p38 MAPK pathway regulates nuclear localization of the transcription factor SKN-1 in oxidative stress response. , 2005, Genes & development.