Using methods of time series data mining to recognize the influences of environmental factors on epileptic seizures

Abstract This research investigated whether environmental factors are important triggers for epileptic seizures. Epilepsy is a very common neurological disease whose exact pathology remains unknown. Numerous studies have observed that environmental changes can be important triggers for various illnesses. Incorporating a nationwide dataset, environmental factors were characterized as inducers for epilepsy using conventional methods and a recently-proposed algorithm of time series data mining. From iterative verification using these algorithms, epilepsy incidence increments were established in January and February of each year. Furthermore, epilepsy incidence was positively correlated with atmospheric pressure, and negatively correlated with ambient temperature. In summary, environmental factors might be important triggers for epilepsy, and the mined epidemiological properties are expected to be helpful for management of this disease.

[1]  C. Arias,et al.  Toscana meningoencephalitis: a comparison to other viral central nervous system infections. , 2012, Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology.

[2]  Wei-Zen Sun,et al.  Analyzing seasonal incidence patterns of epileptic seizure using various statistical methods , 2016, 2016 International Conference on Machine Learning and Cybernetics (ICMLC).

[3]  Z. Kazibutowska,et al.  Seizure frequency and bioelectric brain activity in epileptic patients in stable and unstable atmospheric pressure and temperature in different seasons of the year--a preliminary report. , 2011, Neurologia i neurochirurgia polska.

[4]  F. Sung,et al.  Varicella Vaccination Alters the Chronological Trends of Herpes Zoster and Varicella , 2013, PloS one.

[5]  O. Witte,et al.  Weather as a risk factor for epileptic seizures: A case‐crossover study , 2017, Epilepsia.

[6]  B. Paradowski,et al.  Epilepsy in middle-aged and elderly people: a three-year observation. , 2005, Epileptic disorders : international epilepsy journal with videotape.

[7]  M. Procopio,et al.  Seasonality of birth in Epilepsy: A Southern Hemisphere study , 2006, Seizure.

[8]  J. Miller,et al.  Do atmospheric pressure changes influence seizure occurrence in the epilepsy monitoring unit? , 2009, Epilepsy & Behavior.

[9]  E. Stoupel,et al.  Admissions of patients with epileptic seizures (E) and dizziness (D) related to geomagnetic and solar activity levels: differences in female and male patients. , 1991, Medical hypotheses.

[10]  Norden E. Huang,et al.  A review on Hilbert‐Huang transform: Method and its applications to geophysical studies , 2008 .

[11]  R. Gwinn,et al.  Atmospheric Pressure and Seizure Frequency in the Epilepsy Unit: Preliminary Observations , 2007, Epilepsia.

[12]  Z. Memish,et al.  Epidemiology and impact of varicella vaccination: a longitudinal study 1994-2011. , 2013, Travel medicine and infectious disease.

[13]  Samuel F. Berkovic,et al.  Human epilepsies: interaction of genetic and acquired factors , 2006, Trends in Neurosciences.

[14]  Reese Graves,et al.  Febrile seizures: risks, evaluation, and prognosis. , 2012, American family physician.

[15]  A. Szűcs,et al.  Correction of vitamin D deficiency improves seizure control in epilepsy: A pilot study , 2012, Epilepsy & Behavior.

[16]  Arnold J Wilkins,et al.  Potential of wind turbines to elicit seizures under various meteorological conditions , 2009, Epilepsia.

[17]  W. Hauser,et al.  Comment on Epileptic Seizures and Epilepsy: Definitions Proposed by the International League Against Epilepsy (ILAE) and the International Bureau for Epilepsy (IBE) , 2005, Epilepsia.

[18]  M. Danesi Seasonal variation in the incidence of photoparoxysmal discharges among patients investigated after a single seizure. , 1989, Journal of neurology, neurosurgery, and psychiatry.

[19]  D. Fabó,et al.  Seasonality in epileptic seizures , 2013 .

[20]  Ross Upshur,et al.  Seasonality of primary care utilization for respiratory diseases in Ontario: A time-series analysis , 2008, BMC health services research.

[21]  H. Levine,et al.  Secular trends of chickenpox among military population in Israel in relation to introduction of varicella zoster vaccine 1979–2010 , 2013, Human vaccines & immunotherapeutics.

[22]  L. Cohen,et al.  Transcranial magnetic stimulation for the treatment of seizures: A controlled study , 2002, Neurology.