Front–End Architecture Design for Low-Complexity 3-D Ultrasound Imaging Based on Synthetic Aperture Sequential Beamforming

The 3-D ultrasound imaging provides distinct advantages over its 2-D counterpart leading to a more accurate analysis of tumors and cysts. However, the front end of a 3-D system must receive and process data at prodigious rates, making it impractical for power-constrained portable systems. Synthetic aperture sequential beamforming (SASB) is an ultrasound beamforming technique that splits the computation into two stages, such that the computation in Stage 1 can be completed in the power-constrained front end while the remaining computation can be done elsewhere. In this article, we present several algorithmic and architectural techniques to enable efficient computation of Stage 1 processing without compromising imaging quality. Specifically, we present algorithmic techniques that reduce the computational complexity in Stage 1 by $17\times $ through a systematic reduction in the number of apodization coefficients. We propose a 3-D die stacked architecture where the signals received by 961 active transducers are digitized, routed by a network-on-chip, and processed in parallel. This architecture does not require the explicit storage of incoming data samples. We synthesize the architecture using TSMC 28-nm technology node. The front-end power consumption is around 1.5 W, making it suitable for portable applications.

[1]  Ronald G. Dreslinski,et al.  TETRIS: A Streaming Accelerator for Physics-Limited 3D Plane-Wave UItrasound Imaging , 2019, 2019 56th ACM/IEEE Design Automation Conference (DAC).

[2]  K. Martin Introduction to B-mode imaging , 2019, Diagnostic Ultrasound.

[3]  Jean-Philippe Thiran,et al.  Towards Ultrasound Everywhere: A Portable 3D Digital Back-End Capable of Zone and Compound Imaging , 2018, IEEE Transactions on Biomedical Circuits and Systems.

[4]  Chaitali Chakrabarti,et al.  High volume rate 3D ultrasound imaging based on synthetic aperture sequential beamforming , 2017, 2017 IEEE International Ultrasonics Symposium (IUS).

[5]  J⊘rgen Arendt Jensen,et al.  Real-time implementation of synthetic aperture vector flow imaging on a consumer-level tablet , 2017, 2017 IEEE International Ultrasonics Symposium (IUS).

[6]  Hamed Bouzari,et al.  Synthetic aperture sequential beamforming using spatial matched filtering , 2017, 2017 IEEE International Ultrasonics Symposium (IUS).

[7]  Luca Benini,et al.  Efficient Sample Delay Calculation for 2-D and 3-D Ultrasound Imaging , 2017, IEEE Transactions on Biomedical Circuits and Systems.

[8]  Ming Yang,et al.  Low Complexity 3D Ultrasound Imaging Using Synthetic Aperture Sequential Beamforming , 2016, 2016 IEEE International Workshop on Signal Processing Systems (SiPS).

[9]  Tommaso Di Ianni,et al.  System-level Design of an Integrated Receiver Front-end for a Wireless Ultrasound Probe. , 2016, IEEE transactions on ultrasonics, ferroelectrics, and frequency control.

[10]  Luca Benini,et al.  Ekho: A 30.3W, 10k-Channel Fully Digital Integrated 3-D Beamformer for Medical Ultrasound Imaging Achieving 298M Focal Points per Second , 2016, IEEE Transactions on Very Large Scale Integration (VLSI) Systems.

[11]  Jae Jin Lee,et al.  A System-on-Chip Solution for Point-of-Care Ultrasound Imaging Systems: Architecture and ASIC Implementation , 2016, IEEE Transactions on Biomedical Circuits and Systems.

[12]  B. P. Nelson,et al.  Out of hospital point of care ultrasound: current use models and future directions , 2016, European Journal of Trauma and Emergency Surgery.

[13]  Nico de Jong,et al.  Synthetic Aperture Sequential Beamforming for phased array imaging , 2015, 2015 IEEE International Ultrasonics Symposium (IUS).

[14]  Eunji Jeong,et al.  Smartphone-based portable ultrasound imaging system: Prototype implementation and evaluation , 2015, 2015 IEEE International Ultrasonics Symposium (IUS).

[15]  Yonina C. Eldar,et al.  Sub-Nyquist Sampling and Fourier Domain Beamforming in Volumetric Ultrasound Imaging , 2015, IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control.

[16]  Byungsub Kim,et al.  A Single-Chip 32-Channel Analog Beamformer With 4-ns Delay Resolution and 768-ns Maximum Delay Range for Ultrasound Medical Imaging With a Linear Array Transducer , 2015, IEEE Transactions on Biomedical Circuits and Systems.

[17]  Ming Yang,et al.  Separable Beamforming For 3-D Medical Ultrasound Imaging , 2015, IEEE Transactions on Signal Processing.

[18]  Byungsub Kim,et al.  An Analog-Digital Hybrid RX Beamformer Chip With Non-Uniform Sampling for Ultrasound Medical Imaging With 2D CMUT Array , 2014, IEEE Transactions on Biomedical Circuits and Systems.

[19]  Martin Christian Hemmsen,et al.  Synthetic Aperture Sequential Beamforming implemented on multi-core platforms , 2014, 2014 IEEE International Ultrasonics Symposium.

[20]  Sung-Bae Park,et al.  A novel beamforming method for wireless ultrasound smart probe , 2014, 2014 IEEE International Ultrasonics Symposium.

[21]  Yonina C. Eldar,et al.  Fourier-domain beamforming: the path to compressed ultrasound imaging , 2013, IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control.

[22]  Ming Yang,et al.  Sonic Millip3De with dynamic receive focusing and apodization optimization , 2013, 2013 IEEE International Ultrasonics Symposium (IUS).

[23]  Nan Jiang,et al.  A detailed and flexible cycle-accurate Network-on-Chip simulator , 2013, 2013 IEEE International Symposium on Performance Analysis of Systems and Software (ISPASS).

[24]  Radu Marculescu,et al.  Modeling, Analysis and Optimization of Network-on-Chip Communication Architectures , 2013, Lecture Notes in Electrical Engineering.

[25]  Ming Yang,et al.  Sonic Millip3De: A massively parallel 3D-stacked accelerator for 3D ultrasound , 2013, 2013 IEEE 19th International Symposium on High Performance Computer Architecture (HPCA).

[26]  Yangmo Yoo,et al.  A single FPGA-based portable ultrasound imaging system for point-of-care applications , 2012, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[27]  Yuan-Ching Lien,et al.  A 4.5-mW 8-b 750-MS/s 2-b/step asynchronous subranged SAR ADC in 28-nm CMOS technology , 2012, 2012 Symposium on VLSI Circuits (VLSIC).

[28]  C. Moore,et al.  Point-of-care ultrasonography. , 2011, The New England journal of medicine.

[29]  Ümit Y. Ogras,et al.  On-chip communication architecture exploration: A quantitative evaluation of point-to-point, bus, and network-on-chip approaches , 2007, TODE.

[30]  R. Cobbold Foundations of Biomedical Ultrasound , 2006 .

[31]  R. Pridham,et al.  Digital interpolation beamforming for low-pass and bandpass signals , 1979, Proceedings of the IEEE.

[32]  T. Wenisch,et al.  High-Volume-Rate 3-D Ultrasound Imaging Based on Synthetic Aperture Sequential Beamforming With Chirp-Coded Excitation , 2018, IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control.

[33]  Paul L. M. J. van Neer,et al.  F– k Domain Imaging for Synthetic Aperture Sequential Beamforming , 2016, IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control.

[34]  Ming Yang,et al.  High Frame Rate 3-D Ultrasound Imaging Using Separable Beamforming , 2015, J. Signal Process. Syst..

[35]  Jørgen Arendt Jensen,et al.  Sequential beamforming for synthetic aperture imaging. , 2013, Ultrasonics.

[36]  Natalie D. Enright Jerger,et al.  Outstanding Research Problems in NoC Design: System, Microarchitecture, and Circuit Perspectives , 2009, IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems.

[37]  J. Arendt Paper presented at the 10th Nordic-Baltic Conference on Biomedical Imaging: Field: A Program for Simulating Ultrasound Systems , 1996 .

[38]  B.D. Steinberg,et al.  Digital beamforming in ultrasound , 1992, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[39]  J. Jensen,et al.  Calculation of pressure fields from arbitrarily shaped, apodized, and excited ultrasound transducers , 1992, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[40]  M S Patterson,et al.  The improvement and quantitative assessment of B-mode images produced by an annular array/cone hybrid. , 1983, Ultrasonic imaging.

[41]  J. MacQueen Some methods for classification and analysis of multivariate observations , 1967 .