Auxin-responsive gene expression: genes, promoters and regulatory factors

A molecular approach to investigate auxin signaling in plants has led to the identification of several classes of early/primary auxin response genes. Within the promoters of these genes, cis elements that confer auxin responsiveness (referred to as auxin-response elements or AuxREs) have been defined, and a family of trans-acting transcription factors (auxin-response factors or ARFs) that bind with specificity to AuxREs has been characterized. A family of auxin regulated proteins referred to as Aux/IAA proteins also play a key role in regulating these auxin-response genes. Auxin may regulate transcription on early response genes by influencing the types of interactions between ARFs and Aux/IAAs.

[1]  G. Hagen,et al.  Rapid induction of selective transcription by auxins , 1985, Molecular and cellular biology.

[2]  J. Nemhauser,et al.  ETTIN patterns the Arabidopsis floral meristem and reproductive organs. , 1997, Development.

[3]  J. Tokuhisa,et al.  OCSBF-1, a maize ocs enhancer binding factor: isolation and expression during development. , 1990, The Plant cell.

[4]  G. Hagen,et al.  The ARF family of transcription factors and their role in plant hormone-responsive transcription , 1998, Cellular and Molecular Life Sciences CMLS.

[5]  T. Guilfoyle.  Chapter 19 - Auxin-regulated genes and promoters , 1999 .

[6]  D. Inzé,et al.  Auxin Transport Promotes Arabidopsis Lateral Root Initiation , 2001, Plant Cell.

[7]  G. Hagen,et al.  Auxin-regulated gene expression in intact soybean hypocotyl and excised hypocotyl sections , 1984, Planta.

[8]  C. Perrot-Rechenmann,et al.  Molecular cloning and expression of the early auxin-responsive Aux/IAA gene family in Nicotiana tabacum. , 1998, Plant & cell physiology.

[9]  P. Oeller,et al.  Early auxin-induced genes encode short-lived nuclear proteins. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[10]  G. Hagen,et al.  ARF1, a transcription factor that binds to auxin response elements. , 1997, Science.

[11]  H. Mori,et al.  cDNA Cloning of Indole-3-Acetic Acid-Regulated Genes: Aux22 and SAUR from Mung Bean (Vigna radiata) Hypocotyl Tissue , 1992 .

[12]  A. Theologis,et al.  Degradation of Aux/IAA proteins is essential for normal auxin signalling. , 2000, The Plant journal : for cell and molecular biology.

[13]  T. Guilfoyle,et al.  Characterization of a class of small auxin-inducible soybean polyadenylated RNAs , 1987, Plant Molecular Biology.

[14]  G. Hagen,et al.  Auxin-Regulated Transcription , 1993 .

[15]  DFL1, an auxin-responsive GH3 gene homologue, negatively regulates shoot cell elongation and lateral root formation, and positively regulates the light response of hypocotyl length. , 2001 .

[16]  T. Anai,et al.  Isolation and characterization of an auxin-inducible SAUR gene from radish seedlings. , 1998, DNA sequence : the journal of DNA sequencing and mapping.

[18]  R. W. Davis,et al.  Rapid induction of specific mRNAs by auxin in pea epicotyl tissue. , 1985, Journal of molecular biology.

[19]  Ottoline Leyser,et al.  An Auxin-Dependent Distal Organizer of Pattern and Polarity in the Arabidopsis Root , 1999, Cell.

[20]  A. Theologis,et al.  ThePS-IAA4/5-like Family of Early Auxin-inducible mRNAs inArabidopsis thaliana , 1995 .

[21]  T. Zarembinski,et al.  Biochemical characterization of recombinant polypeptides corresponding to the predicted ²±± fold in Aux/IAA proteins , 1999 .

[22]  C. Hardtke,et al.  The Arabidopsis gene MONOPTEROS encodes a transcription factor mediating embryo axis formation and vascular development , 1998, The EMBO journal.

[23]  R. T. Nagao,et al.  Sequence and characterization of two auxin-regulated genes from soybean. , 1988, The Journal of biological chemistry.

[24]  M. Estelle,et al.  Function of the ubiquitin-proteasome pathway in auxin response. , 2000, Trends in biochemical sciences.

[25]  G. Hagen,et al.  Aux/IAA proteins repress expression of reporter genes containing natural and highly active synthetic auxin response elements. , 1997, The Plant cell.

[26]  G. Hagen,et al.  Soybean GH3 promoter contains multiple auxin-inducible elements. , 1994, The Plant cell.

[27]  G. Hagen,et al.  Composite structure of auxin response elements. , 1995, The Plant cell.

[28]  J. Chory,et al.  Suppressors of an Arabidopsis thaliana phyB mutation identify genes that control light signaling and hypocotyl elongation. , 1998, Genetics.

[29]  A. Theologis,et al.  The PS-IAA4/5-like family of early auxin-inducible mRNAs in Arabidopsis thaliana. , 1995, Journal of molecular biology.

[30]  P. Green,et al.  Characterization of the Auxin-Inducible SAUR-AC1 Gene for Use as a Molecular Genetic Tool in Arabidopsis , 1994, Plant physiology.

[31]  K. Ljung,et al.  Auxin-induced K+ channel expression represents an essential step in coleoptile growth and gravitropism. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[32]  A. Theologis,et al.  IAA17/AXR3: Biochemical Insight into an Auxin Mutant Phenotype , 2001, Plant Cell.

[33]  T. Guilfoyle,et al.  Induction and superinduction of auxin-responsive mRNAs with auxin and protein synthesis inhibitors. , 1990, The Journal of biological chemistry.

[34]  G. Hagen,et al.  Identification of Arabidopsis Histone Deacetylase HDA6 Mutants That Affect Transgene Expression , 2001, Plant Cell.

[35]  K. Mockaitis,et al.  Auxin induces mitogenic activated protein kinase (MAPK) activation in roots of Arabidopsis seedlings. , 2000, The Plant journal : for cell and molecular biology.

[36]  G. Hagen,et al.  The ocs element in the soybean GH2/4 promoter is activated by both active and inactive auxin and salicylic acid analogues , 1994, Plant Molecular Biology.

[37]  E. Liscum,et al.  Genetics of Aux/IAA and ARF action in plant growth and development , 2002, Plant Molecular Biology.

[38]  S. Abel,et al.  Aux/IAA proteins are phosphorylated by phytochrome in vitro. , 2000, Plant physiology.

[39]  G. Hagen,et al.  Expression of the Auxin-Inducible GH3 Promoter/GUS Fusion Gene as a Useful Molecular Marker for Auxin Physiology , 1999 .

[40]  J. Chory,et al.  A role for flavin monooxygenase-like enzymes in auxin biosynthesis. , 2001, Science.

[41]  J. Tokuhisa,et al.  Does the ocs-element occur as a functional component of the promoters of plant genes? , 1993, The Plant Journal.

[42]  T. Guilfoyle,et al.  Rapid redistribution of auxin-regulated RNAs during gravitropism. , 1989, Science.

[43]  G. Tena,et al.  Functional analysis of oxidative stress-activated mitogen-activated protein kinase cascade in plants. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[44]  C. Perrot-Rechenmann,et al.  Isolation by differential display and characterization of a tobacco auxin‐responsive cDNA Nt‐gh3, related to GH3 , 1997, FEBS letters.

[45]  A. Theologis,et al.  A polymorphic bipartite motif signals nuclear targeting of early auxin-inducible proteins related to PS-IAA4 from pea (Pisum sativum). , 1995, The Plant journal : for cell and molecular biology.

[46]  B. Poovaiah,et al.  Molecular and Biochemical Evidence for the Involvement of Calcium/Calmodulin in Auxin Action* , 2000, The Journal of Biological Chemistry.

[47]  G. Hagen,et al.  Activation and repression of transcription by auxin-response factors. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[48]  B. Bartel,et al.  A Gain-of-Function Mutation in IAA28 Suppresses Lateral Root Development , 2001, Plant Cell.

[49]  P. LaFayette,et al.  Structure and expression of two auxin-inducible genes from Arabidopsis , 1990, Plant Molecular Biology.

[50]  J. Reed,et al.  Control of auxin-regulated root development by the Arabidopsis thaliana SHY2/IAA3 gene. , 1999, Development.

[51]  M. Matsui,et al.  FIN219, an auxin-regulated gene, defines a link between phytochrome A and the downstream regulator COP1 in light control of Arabidopsis development. , 2000, Genes & development.

[52]  M. Estelle,et al.  The role of regulated protein degradation in auxin response , 2002, Plant Molecular Biology.

[53]  P. Herrmann,et al.  FUSCA3 encodes a protein with a conserved VP1/ABI3-like B3 domain which is of functional importance for the regulation of seed maturation in Arabidopsis thaliana. , 1998, The Plant journal : for cell and molecular biology.

[54]  K. Ohmiya,et al.  RAV1, a novel DNA-binding protein, binds to bipartite recognition sequence through two distinct DNA-binding domains uniquely found in higher plants. , 1999, Nucleic acids research.

[55]  T. Yoshizumi,et al.  DFL1, an auxin-responsive GH3 gene homologue, negatively regulates shoot cell elongation and lateral root formation, and positively regulates the light response of hypocotyl length. , 2008, The Plant journal : for cell and molecular biology.

[56]  J. L. Key,et al.  Isolation of cloned cDNAs to auxin-responsive poly(A)RNAs of elongating soybean hypocotyl. , 1982, Proceedings of the National Academy of Sciences of the United States of America.

[57]  Yi Li,et al.  Auxin-induced expression of the soybean GH3 promoter in transgenic tobacco plants , 1991, Plant Molecular Biology.

[58]  G. Hagen,et al.  How does auxin turn on genes? , 1998, Plant physiology.

[59]  H. Goodman,et al.  Isolation of the Arabidopsis ABI3 gene by positional cloning. , 1992, The Plant cell.

[60]  X. Deng,et al.  The role of COP1 in repression of Arabidopsis photomorphogenic development. , 1999, Trends in cell biology.

[61]  G. Hagen,et al.  Dimerization and DNA binding of auxin response factors. , 1999, The Plant journal : for cell and molecular biology.

[62]  G. Hagen,et al.  Tissue-specific and organ-specific expression of soybean auxin-responsive transcripts GH3 and SAURs. , 1991, The Plant cell.

[63]  P. Hooykaas.  Biochemistry and Molecular Biology of Plant Hormones , 1999 .

[64]  F. Katagiri,et al.  Two tobacco DNA-binding proteins with homology to the nuclear factor CREB , 1989, Nature.

[65]  C. Perrot-Rechenmann,et al.  Expression of auxin‐regulated genes , 1997 .

[66]  D. McCarty,et al.  The Viviparous-1 developmental gene of maize encodes a novel transcriptional activator , 1991, Cell.

[67]  W. Chiu,et al.  Suppression of auxin signal transduction by a MAPK cascade in higher plants , 1998, Nature.

[68]  K. Mockaitis,et al.  Protein phosphorylation in the delivery of and response to auxin signals , 2002, Plant Molecular Biology.

[69]  N. Graham,et al.  Auxin cross-talk: integration of signalling pathways to control plant development. , 2002 .

[70]  P. Oeller,et al.  Structural characterization of the early indoleacetic acid-inducible genes, PS-IAA4/5 and PS-IAA6, of pea (Pisum sativum L.). , 1993, Journal of molecular biology.

[71]  F. B. Pickett,et al.  The AXR1 and AUX1 genes of Arabidopsis function in separate auxin-response pathways. , 1995, The Plant journal : for cell and molecular biology.

[72]  N. Chua,et al.  Arabidopsis NAC1 transduces auxin signal downstream of TIR1 to promote lateral root development. , 2000, Genes & development.

[73]  J. Kim,et al.  Protein-protein interactions among the Aux/IAA proteins. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[74]  G. Hagen,et al.  The soybean SAUR open reading frame contains a cis element responsible for cycloheximide-induced mRNA accumulation , 1994, Plant Molecular Biology.

[75]  G. Hagen,et al.  An auxin-induced polypeptide in dicotyledonous plants , 1987, Plant Molecular Biology.

[76]  A. Theologis,et al.  age Mutants of Arabidopsis Exhibit Altered Auxin-Regulated Gene Expression , 1998, Plant Cell.

[77]  M. Ohme-Takagi,et al.  DST sequences, highly conserved among plant SAUR genes, target reporter transcripts for rapid decay in tobacco. , 1993, The Plant cell.

[78]  A. Nebenführ,et al.  The diageotropica mutation alters auxin induction of a subset of the Aux/IAA gene family in tomato , 2000, Plant Molecular Biology.

[79]  E. Liscum,et al.  The NPH4 Locus Encodes the Auxin Response Factor ARF7, a Conditional Regulator of Differential Growth in Aerial Arabidopsis Tissue , 2000, Plant Cell.

[80]  A. Theologis,et al.  Early Genes and Auxin Action , 1996, Plant physiology.