The equivalence of a human observer and an ideal observer in binary diagnostic tasks

The Ideal Observer (IO) is “ideal” for given data populations. In the image perception process, as the raw images are degraded by factors such as display and eye optics, there is an equivalent IO (EIO). The EIO uses the statistical information that exits the perception/cognitive degradations as the data. We assume a human observer who received sufficient training, e.g., radiologists, and hypothesize that such a human observer can be modeled as if he is an EIO. To measure the likelihood ratio (LR) distributions of an EIO, we formalize experimental design principles that encourage rationality based on von Neumann and Morgenstern’s (vNM) axioms. We present examples to show that many observer study design refinements, although motivated by empirical principles explicitly, implicitly encourage rationality. Our hypothesis is supported by a recent review paper on ROC curve convexity by Pesce, Metz, and Berbaum. We also provide additional evidence based on a collection of observer studies in medical imaging. EIO theory shows that the “sub-optimal” performance of a human observer can be mathematically formalized in the form of an IO, and measured through rationality encouragement.

[1]  G. A. Miller THE PSYCHOLOGICAL REVIEW THE MAGICAL NUMBER SEVEN, PLUS OR MINUS TWO: SOME LIMITS ON OUR CAPACITY FOR PROCESSING INFORMATION 1 , 1956 .

[2]  S C Kao,et al.  Evaluation of a digital workstation for interpreting neonatal examinations. A receiver operating characteristic study. , 1992, Investigative radiology.

[3]  H. Barrett,et al.  Objective assessment of image quality. III. ROC metrics, ideal observers, and likelihood-generating functions. , 1998, Journal of the Optical Society of America. A, Optics, image science, and vision.

[4]  Dawid Schellingerhout,et al.  Projected digital radiologic images for teaching: balance of image quality with data size constraints. , 2002, Academic radiology.

[5]  Charles E Metz,et al.  ROC analysis in medical imaging: a tutorial review of the literature , 2008, Radiological physics and technology.

[6]  Jill L. King,et al.  Forced choice and ordinal discrete rating assessment of image quality: A comparison , 2009, Journal of Digital Imaging.

[7]  Lorenzo L. Pesce,et al.  On the convexity of ROC curves estimated from radiological test results. , 2010, Academic radiology.

[8]  Xin He,et al.  Three-Class ROC Analysis—Toward a General Decision Theoretic Solution , 2010, IEEE Transactions on Medical Imaging.

[9]  B. Erickson,et al.  Optimal Presentation Modes for Detecting Brain Tumor Progression , 2011, American Journal of Neuroradiology.

[10]  E. Halpern,et al.  Assessing radiologist performance using combined digital mammography and breast tomosynthesis compared with digital mammography alone: results of a multicenter, multireader trial. , 2013, Radiology.