Mechanisms of cholestasis.
暂无分享,去创建一个
[1] Joanna Girling,et al. Intrahepatic cholestasis of pregnancy , 2022, BJOG : an international journal of obstetrics and gynaecology.
[2] J. Boyer,et al. Molecular pathogenesis of cholestasis. , 2012, The New England journal of medicine.
[3] H. Fukui,et al. Disturbed colocalization of multidrug resistance protein 2 and radixin in human cholestatic liver diseases , 2008, Journal of gastroenterology and hepatology.
[4] K. Zatloukal,et al. Expression of bile acid synthesis and detoxification enzymes and the alternative bile acid efflux pump MRP4 in patients with primary biliary cirrhosis , 2007, Liver international : official journal of the International Association for the Study of the Liver.
[5] F. Lammert,et al. Functional variants of the central bile acid sensor FXR identified in intrahepatic cholestasis of pregnancy. , 2007, Gastroenterology.
[6] M. Trauner,et al. Principles of hepatic organic anion transporter regulation during cholestasis, inflammation and liver regeneration. , 2007, Biochimica et biophysica acta.
[7] M. Trauner,et al. MDR3 (ABCB4) defects: a paradigm for the genetics of adult cholestatic syndromes. , 2007, Seminars in liver disease.
[8] T. Wienker,et al. Linkage between a new splicing site mutation in the MDR3 alias ABCB4 gene and intrahepatic cholestasis of pregnancy , 2007, Hepatology.
[9] P. Meier,et al. Mutations and polymorphisms in the bile salt export pump and the multidrug resistance protein 3 associated with drug-induced liver injury , 2007, Pharmacogenetics and genomics.
[10] P. Meier,et al. Hepatobiliary transporters and drug‐induced cholestasis , 2006, Hepatology.
[11] J. Boyer,et al. Radixin is required to maintain apical canalicular membrane structure and function in rat hepatocytes. , 2006, Gastroenterology.
[12] L. Mattsson,et al. Intrahepatic cholestasis of pregnancy: the severe form is associated with common variants of the hepatobiliary phospholipid transporter ABCB4 gene , 2006, Gut.
[13] D. Häussinger,et al. Combined mutations of canalicular transporter proteins cause severe intrahepatic cholestasis of pregnancy. , 2006, Gastroenterology.
[14] Richard J. Thompson,et al. Hepatocellular carcinoma in ten children under five years of age with bile salt export pump deficiency , 2006, Hepatology.
[15] L. Pawlikowska,et al. Atp8b1 deficiency in mice reduces resistance of the canalicular membrane to hydrophobic bile salts and impairs bile salt transport , 2006, Hepatology.
[16] M. Trauner,et al. Molecular mechanisms of cholestasis , 2006, Wiener Medizinische Wochenschrift.
[17] Rick Moore,et al. Estrogen Receptor α Mediates 17α-Ethynylestradiol Causing Hepatotoxicity* , 2006, Journal of Biological Chemistry.
[18] A. Floreani,et al. Intrahepatic cholestasis of pregnancy: three novel MDR3 gene mutations , 2006, Alimentary pharmacology & therapeutics.
[19] J. Marin,et al. Potential role of trans-inhibition of the bile salt export pump by progesterone metabolites in the etiopathogenesis of intrahepatic cholestasis of pregnancy. , 2006, Journal of hepatology.
[20] M. Trauner,et al. Role of nuclear receptors in the adaptive response to bile acids and cholestasis: pathogenetic and therapeutic considerations. , 2006, Molecular pharmaceutics.
[21] K. Lazaridis,et al. Genetics of hepatobiliary diseases. , 2006, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.
[22] H. Denk,et al. Coordinated induction of bile acid detoxification and alternative elimination in mice: role of FXR-regulated organic solute transporter-alpha/beta in the adaptive response to bile acids. , 2006, American journal of physiology. Gastrointestinal and liver physiology.
[23] K. Aittomäki,et al. Intrahepatic cholestasis of pregnancy as an indicator of liver and biliary diseases: A population‐based study , 2006, Hepatology.
[24] David A. Taylor,et al. Safe Harbor: Protecting Ports with Shipboard Fuel Cells , 2006, Environmental health perspectives.
[25] M. Trauner,et al. Fxr−/− mice adapt to biliary obstruction by enhanced phase I detoxification and renal elimination of bile acids Published, JLR Papers in Press, December 4, 2005. , 2006, Journal of Lipid Research.
[26] C. Paulusma,et al. Hepatocanalicular transport defects: pathophysiologic mechanisms of rare diseases. , 2006, Gastroenterology.
[27] P. Dawson,et al. OSTα‐OSTβ: A major basolateral bile acid and steroid transporter in human intestinal, renal, and biliary epithelia , 2005 .
[28] S. Taylor-Robinson,et al. ATP8B1 mutations in British cases with intrahepatic cholestasis of pregnancy , 2005, Gut.
[29] D. Keppler,et al. Expression and localization of hepatobiliary transport proteins in progressive familial intrahepatic cholestasis , 2005, Hepatology.
[30] V. Balan,et al. Lack of Association of Common Cystic Fibrosis Transmembrane Conductance Regulator Gene Mutations with Primary Sclerosing Cholangitis , 2005, The American Journal of Gastroenterology.
[31] P. Dawson,et al. The Heteromeric Organic Solute Transporter α-β, Ostα-Ostβ, Is an Ileal Basolateral Bile Acid Transporter* , 2005, Journal of Biological Chemistry.
[32] U. Diczfalusy,et al. Novel pathways of bile acid metabolism involving CYP3A4. , 2005, Biochimica et biophysica acta.
[33] G. Kullak-Ublick,et al. Coordinate transcriptional regulation of bile acid homeostasis and drug metabolism. , 2005, Archives of biochemistry and biophysics.
[34] K. Faber,et al. LPS-induced downregulation of MRP2 and BSEP in human liver is due to a posttranscriptional process. , 2004, American journal of physiology. Gastrointestinal and liver physiology.
[35] N. LaRusso,et al. The cholangiopathies: disorders of biliary epithelia. , 2004, Gastroenterology.
[36] A. Smahi,et al. Claudin-1 gene mutations in neonatal sclerosing cholangitis associated with ichthyosis: a tight junction disease. , 2004, Gastroenterology.
[37] R. Houwen,et al. Benign recurrent intrahepatic cholestasis type 2 is caused by mutations in ABCB11. , 2004, Gastroenterology.
[38] R. Yantiss,et al. Induction of colitis in cftr-/- mice results in bile duct injury. , 2004, American journal of physiology. Gastrointestinal and liver physiology.
[39] H. Tilg,et al. Regurgitation of bile acids from leaky bile ducts causes sclerosing cholangitis in Mdr2 (Abcb4) knockout mice. , 2004, Gastroenterology.
[40] J. Boyer,et al. Multidrug resistance-associated protein 4 is up-regulated in liver but down-regulated in kidney in obstructive cholestasis in the rat. , 2004, Journal of hepatology.
[41] P. Boelle,et al. ABCB4 gene mutations and primary sclerosing cholangitis. , 2004, Gastroenterology.
[42] C. Liddle,et al. Feed-forward Regulation of Bile Acid Detoxification by CYP3A4 , 2004, Journal of Biological Chemistry.
[43] P. Meier,et al. BSEP and MDR3 haplotype structure in healthy Caucasians, primary biliary cirrhosis and primary sclerosing cholangitis , 2004, Hepatology.
[44] J. Chiang. Regulation of bile acid synthesis: pathways, nuclear receptors, and mechanisms. , 2004, Journal of hepatology.
[45] F. Lammert,et al. From genotypes to haplotypes in hepatobiliary diseases: One plus one equals (sometimes) more than two , 2004, Hepatology.
[46] P. Meier,et al. Sequence analysis of bile salt export pump (ABCB11) and multidrug resistance p-glycoprotein 3 (ABCB4, MDR3) in patients with intrahepatic cholestasis of pregnancy. , 2004, Pharmacogenetics.
[47] M. Arrese,et al. Is intrahepatic cholestasis of pregnancy an MDR3-related disease? , 2003, Gastroenterology.
[48] C. Handschin,et al. Induction of Drug Metabolism: The Role of Nuclear Receptors , 2003, Pharmacological Reviews.
[49] E. Elias,et al. Obstetric cholestasis with elevated gamma glutamyl transpeptidase: Incidence, presentation and treatment , 2003, Journal of gastroenterology and hepatology.
[50] D. Keppler,et al. Changes in the expression and localization of hepatocellular transporters and radixin in primary biliary cirrhosis. , 2003, Journal of hepatology.
[51] M. Vore,et al. Biliary Secretion of Glutathione in Estradiol 17β-d-Glucuronide-Induced Cholestasis , 2003, Journal of Pharmacology and Experimental Therapeutics.
[52] K. Zatloukal,et al. Role of nuclear bile acid receptor, FXR, in adaptive ABC transporter regulation by cholic and ursodeoxycholic acid in mouse liver, kidney and intestine. , 2003, Journal of hepatology.
[53] L. Klomp,et al. Progressive familial intrahepatic cholestasis type 1 and extrahepatic features: no catch-up of stature growth, exacerbation of diarrhea, and appearance of liver steatosis after liver transplantation. , 2003, Journal of hepatology.
[54] C. Gartung,et al. Effects of proinflammatory cytokines on rat organic anion transporters during toxic liver injury and cholestasis , 2003, Hepatology.
[55] P. Boelle,et al. ABCB4 gene mutation-associated cholelithiasis in adults. , 2003, Gastroenterology.
[56] Jingsong Cao,et al. Estradiol-17beta-D-glucuronide induces endocytic internalization of Bsep in rats. , 2003, American journal of physiology. Gastrointestinal and liver physiology.
[57] K. Aittomäki,et al. Genetic evidence of heterogeneity in intrahepatic cholestasis of pregnancy , 2003, Gut.
[58] L. Tsui,et al. Increased prevalence of CFTR mutations and variants and decreased chloride secretion in primary sclerosing cholangitis , 2003, Human Genetics.
[59] K. Zatloukal,et al. Adaptive changes in hepatobiliary transporter expression in primary biliary cirrhosis. , 2003, Journal of hepatology.
[60] W. Lim,et al. Complex inheritance of familial hypercholanemia with associated mutations in TJP2 and BAAT , 2003, Nature Genetics.
[61] J. Boyer,et al. Bile salt transporters: molecular characterization, function, and regulation. , 2003, Physiological reviews.
[62] J. Prieto,et al. A multidrug resistance 3 gene mutation causing cholelithiasis, cholestasis of pregnancy, and adulthood biliary cirrhosis. , 2003, Gastroenterology.
[63] K. Zatloukal,et al. Role of nuclear bile salt receptors Fxr and Pxr in mediating adaptive hepatobiliary transporter response to cholic acid (CA) in mouse liver , 2003 .
[64] M. McCarthy,et al. ABCB4 gene sequence variation in women with intrahepatic cholestasis of pregnancy , 2003, Journal of medical genetics.
[65] K. Feingold,et al. Repression of Farnesoid X Receptor during the Acute Phase Response* , 2003, The Journal of Biological Chemistry.
[66] N. LaRusso,et al. Cytokine-stimulated nitric oxide production inhibits adenylyl cyclase and cAMP-dependent secretion in cholangiocytes. , 2003, Gastroenterology.
[67] C. Andres,et al. A second heterozygous MDR3 nonsense mutation associated with intrahepatic cholestasis of pregnancy , 2003, Journal of medical genetics.
[68] J. Boyer,et al. Down-regulation of the Na+/taurocholate cotransporting polypeptide during pregnancy in the rat. , 2003, Journal of hepatology.
[69] P. Meier,et al. Regulation of basolateral organic anion transporters in ethinylestradiol-induced cholestasis in the rat. , 2003, Biochimica et biophysica acta.
[70] A. Mannermaa,et al. Multidrug resistance 3 gene mutation 1712delT and estrogen receptor alpha gene polymorphisms in Finnish women with obstetric cholestasis. , 2002, European journal of obstetrics, gynecology, and reproductive biology.
[71] B. Stieger,et al. Effects of bile salt flux variations on the expression of hepatic bile salt transporters in vivo in mice. , 2002, Journal of hepatology.
[72] F. Lammert,et al. Ursodeoxycholic acid aggravates bile infarcts in bile duct-ligated and Mdr2 knockout mice via disruption of cholangioles. , 2002, Gastroenterology.
[73] P. Meier,et al. Expression of rat hepatic multidrug resistance-associated proteins and organic anion transporters in pregnancy. , 2002, American journal of physiology. Gastrointestinal and liver physiology.
[74] R. Poupon,et al. Contribution of mrp2 in alterations of canalicular bile formation by the endothelin antagonist bosentan. , 2002, Journal of hepatology.
[75] C. Cazeneuve,et al. Cystic fibrosis transmembrane conductance regulator (CFTR) gene defects in patients with primary sclerosing cholangitis. , 2002, Journal of hepatology.
[76] D. Keppler,et al. Inhibition of transport across the hepatocyte canalicular membrane by the antibiotic fusidate. , 2002, Biochemical pharmacology.
[77] D. Keppler,et al. Radixin deficiency causes conjugated hyperbilirubinemia with loss of Mrp2 from bile canalicular membranes , 2002, Nature Genetics.
[78] Jingsong Cao,et al. Altered localization and activity of canalicular Mrp2 in estradiol‐17β‐D‐glucuronide–induced cholestasis , 2002, Hepatology.
[79] J. Neuberger,et al. Defective regulation of cholangiocyte Cl−/HCO−3 and Na+/H+ exchanger activities in primary biliary cirrhosis , 2002, Hepatology.
[80] S. Karpen. Nuclear receptor regulation of hepatic function. , 2002, Journal of hepatology.
[81] M. Haussler,et al. Vitamin D Receptor As an Intestinal Bile Acid Sensor , 2002, Science.
[82] K. Feingold,et al. Reduction in cytochrome P-450 enzyme expression is associated with repression of CAR (constitutive androstane receptor) and PXR (pregnane X receptor) in mouse liver during the acute phase response. , 2002, Biochemical and biophysical research communications.
[83] E. Gabazza,et al. Increased renal expression of bilirubin glucuronide transporters in a rat model of obstructive jaundice. , 2002, American journal of physiology. Gastrointestinal and liver physiology.
[84] R. Houwen,et al. Benign recurrent intrahepatic cholestasis progressing to progressive familial intrahepatic cholestasis: low GGT cholestasis is a clinical continuum. , 2002, Journal of hepatology.
[85] F. Russel,et al. The MRP4/ABCC4 gene encodes a novel apical organic anion transporter in human kidney proximal tubules: putative efflux pump for urinary cAMP and cGMP. , 2002, Journal of the American Society of Nephrology : JASN.
[86] J. Boyer,et al. Adaptive regulation of bile salt transporters in kidney and liver in obstructive cholestasis in the rat. , 2001, Gastroenterology.
[87] Y. Sugiyama,et al. The expression levels of plasma membrane transporters in the cholestatic liver of patients undergoing biliary drainage and their association with the impairment of biliary secretory function. , 2001 .
[88] R. Evans,et al. Nuclear receptors and lipid physiology: opening the X-files. , 2001, Science.
[89] R. Sokol,et al. Cholangiocyte Biology and Cystic Fibrosis Liver Disease , 2001, Seminars in liver disease.
[90] E. Jacquemin. Role of Multidrug Resistance 3 Deficiency in Pediatric and Adult Liver Disease: One Gene for Three Diseases , 2001, Seminars in liver disease.
[91] Jatinder Lamba,et al. Disrupted Bile Acid Homeostasis Reveals an Unexpected Interaction among Nuclear Hormone Receptors, Transporters, and Cytochrome P450* , 2001, The Journal of Biological Chemistry.
[92] U. Beuers,et al. Expression of hepatic transporters OATP-C and MRP2 in primary sclerosing cholangitis. , 2001, Liver.
[93] F. Di Virgilio,et al. Proinflammatory cytokines inhibit secretion in rat bile duct epithelium. , 2001, Gastroenterology.
[94] F. Lammert,et al. Effects of ursodeoxycholic and cholic acid feeding on hepatocellular transporter expression in mouse liver. , 2001, Gastroenterology.
[95] T. Kawaguchi,et al. Alterations in tight junctions differ between primary biliary cirrhosis and primary sclerosing cholangitis , 2001, Hepatology.
[96] P. Bosma,et al. The wide spectrum of multidrug resistance 3 deficiency: from neonatal cholestasis to cirrhosis of adulthood. , 2001, Gastroenterology.
[97] O. Rosmorduc,et al. MDR3 gene defect in adults with symptomatic intrahepatic and gallbladder cholesterol cholelithiasis. , 2001, Gastroenterology.
[98] J. Boyer,et al. Cellular localization and up‐regulation of multidrug resistance–associated protein 3 in hepatocytes and cholangiocytes during obstructive cholestasis in rat liver , 2001, Hepatology.
[99] Jürg Reichen,et al. The endothelin antagonist bosentan inhibits the canalicular bile salt export pump: A potential mechanism for hepatic adverse reactions , 2001, Clinical pharmacology and therapeutics.
[100] D. Keppler,et al. Up‐regulation of basolateral multidrug resistance protein 3 (Mrp3) in cholestatic rat liver , 2001, Hepatology.
[101] T. Willson,et al. The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[102] R. Evans,et al. An essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[103] C. Funk,et al. Cholestatic potential of troglitazone as a possible factor contributing to troglitazone-induced hepatotoxicity: in vivo and in vitro interaction at the canalicular bile salt export pump (Bsep) in the rat. , 2001, Molecular pharmacology.
[104] K. Zatloukal,et al. Hepatobiliary transporter expression in percutaneous liver biopsies of patients with cholestatic liver diseases , 2001, Hepatology.
[105] M W Whitehead,et al. The causes of obvious jaundice in South West Wales: perceptions versus reality , 2001, Gut.
[106] N. Grishin,et al. Accumulation of dietary cholesterol in sitosterolemia caused by mutations in adjacent ABC transporters. , 2000, Science.
[107] F. Lammert,et al. Intrahepatic cholestasis of pregnancy: molecular pathogenesis, diagnosis and management. , 2000, Journal of hepatology.
[108] G. Szakács,et al. MDR3 P-glycoprotein, a Phosphatidylcholine Translocase, Transports Several Cytotoxic Drugs and Directly Interacts with Drugs as Judged by Interference with Nucleotide Trapping* , 2000, The Journal of Biological Chemistry.
[109] K. Feingold,et al. The Acute Phase Response Is Associated with Retinoid X Receptor Repression in Rodent Liver* , 2000, The Journal of Biological Chemistry.
[110] M. McCarthy,et al. Heterozygous MDR3 missense mutation associated with intrahepatic cholestasis of pregnancy: evidence for a defect in protein trafficking. , 2000, Human molecular genetics.
[111] Y. Sugiyama,et al. Characterization of inducible nature of MRP3 in rat liver. , 2000, American journal of physiology. Gastrointestinal and liver physiology.
[112] P. Meier,et al. Drug- and estrogen-induced cholestasis through inhibition of the hepatocellular bile salt export pump (Bsep) of rat liver. , 2000, Gastroenterology.
[113] Kazuhide Yamamoto,et al. Cytokine Profile in the Liver of Primary Biliary Cirrhosis , 1999, Journal of Clinical Immunology.
[114] Walter E. Gall,et al. Differential glucuronidation of bile acids, androgens and estrogens by human UGT1A3 and 2B7 , 1999, The Journal of Steroid Biochemistry and Molecular Biology.
[115] J. Martí-Climent,et al. Assessment of biliary bicarbonate secretion in humans by positron emission tomography. , 1999, Gastroenterology.
[116] J. Boyer,et al. Molecular regulation of hepatocellular transport systems in cholestasis. , 1999, Journal of hepatology.
[117] D. Keppler,et al. Expression of the MRP2 gene-encoded conjugate export pump in human kidney proximal tubules and in renal cell carcinoma. , 1999, Journal of the American Society of Nephrology : JASN.
[118] K. Wikvall,et al. 6α-Hydroxylation of taurochenodeoxycholic acid and lithocholic acid by CYP3A4 in human liver microsomes , 1999 .
[119] A. Wolkoff,et al. Characterization of the mechanisms involved in the gender differences in hepatic taurocholate uptake. , 1999, American journal of physiology. Gastrointestinal and liver physiology.
[120] M. Hadchouel,et al. Heterozygous non-sense mutation of the MDR3 gene in familial intrahepatic cholestasis of pregnancy , 1999, The Lancet.
[121] G. Hooiveld,et al. Up‐regulation of the multidrug resistance genes, Mrp1 and Mdr1b, and down‐regulation of the organic anion transporter, Mrp2, and the bile salt transporter, Spgp, in endotoxemic rat liver , 1998, Hepatology.
[122] Richard J. Thompson,et al. A gene encoding a liver-specific ABC transporter is mutated in progressive familial intrahepatic cholestasis , 1998, Nature Genetics.
[123] Y. Sugiyama,et al. Hepatic expression of multidrug resistance-associated protein-like proteins maintained in eisai hyperbilirubinemic rats. , 1998, Molecular pharmacology.
[124] J. Boyer,et al. Endotoxin downregulates rat hepatic ntcp gene expression via decreased activity of critical transcription factors. , 1998, The Journal of clinical investigation.
[125] N. Freimer,et al. A gene encoding a P-type ATPase mutated in two forms of hereditary cholestasis , 1998, Nature Genetics.
[126] P. Bosma,et al. Mutations in the MDR3 gene cause progressive familial intrahepatic cholestasis. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[127] D. Beier,et al. Regulation of hepatocyte bile salt transporters during hepatic regeneration. , 1997, The American journal of physiology.
[128] J. Ribalta,et al. Profiles of bile acids and progesterone metabolites in the urine and serum of women with intrahepatic cholestasis of pregnancy. , 1997, Journal of hepatology.
[129] D. Keppler,et al. The rat canalicular conjugate export pump (Mrp2) is down-regulated in intrahepatic and obstructive cholestasis. , 1997, Gastroenterology.
[130] M. Kool,et al. A mutation in the human canalicular multispecific organic anion transporter gene causes the Dubin‐Johnson syndrome , 1997, Hepatology.
[131] G. Mieli-Vergani,et al. Hepatic basolateral sodium‐dependent–bile acid transporter expression in two unusual cases of hypercholanemia and in extrahepatic biliary atresia , 1997, Hepatology.
[132] C. Falany. Enzymology of human cytosolic sulfotransferases , 1997, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[133] J. Prieto,et al. Decreased anion exchanger 2 immunoreactivity in the liver of patients with primary biliary cirrhosis , 1997, Hepatology.
[134] A. Groen,et al. The role of mdr2 P‐glycoprotein in hepatobiliary lipid transport , 1997, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[135] R. Weinshilboum,et al. Sulfotransferase molecular biology: cDNAs and genes , 1997, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[136] C. Gartung,et al. Ethinyl estradiol cholestasis involves alterations in expression of liver sinusoidal transporters. , 1996, The American journal of physiology.
[137] P. Dawson,et al. Comparative analysis of the ontogeny of a sodium-dependent bile acid transporter in rat kidney and ileum. , 1996, The American journal of physiology.
[138] C. Hunt,et al. Survey of cystic fibrosis transmembrane conductance regulator genotypes in primary sclerosing cholangitis , 1996, Digestive Diseases and Sciences.
[139] J. Prieto,et al. Anion exchanger immunoreactivity in human salivary glands in health and Sjögren's syndrome. , 1995, The American journal of pathology.
[140] J. Dufour,et al. Nitric oxide blocks bile canalicular contraction by inhibiting inositol trisphosphate-dependent calcium mobilization. , 1995, Gastroenterology.
[141] N. LaRusso,et al. Isolation of the microtubule-vesicle motor kinesin from rat liver: selective inhibition by cholestatic bile acids. , 1995, Gastroenterology.
[142] A. Groen,et al. Mice with homozygous disruption of the mdr2 P-glycoprotein gene. A novel animal model for studies of nonsuppurative inflammatory cholangitis and hepatocarcinogenesis. , 1994, The American journal of pathology.
[143] P. Borst,et al. Homozygous disruption of the murine MDR2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease , 1993, Cell.
[144] J. Prieto,et al. Abnormal expression of anion exchanger genes in primary biliary cirrhosis. , 1993, Gastroenterology.
[145] D. Chen,et al. Transcriptional regulatory elements for basal expression of cytochrome P450IIC genes. , 1992, The Journal of biological chemistry.
[146] N. Tanaka,et al. Altered bile acid metabolism in liver disease: concurrent occurrence of C-1 and C-6 hydroxylated bile acid metabolites and their preferential excretion into urine. , 1990, Journal of lipid research.
[147] L. Tsui,et al. Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA. , 1989, Science.
[148] M. Kaplan,et al. Primary Biliary Cirrhosis , 1987, The New England journal of medicine.
[149] S. Poucell,et al. Mechanisms of cholestasis. , 1986, Laboratory investigation; a journal of technical methods and pathology.
[150] U. Gundert-Remy,et al. Biliary and urinary excretion of sulfated, glucuronidated and tetrahydroxylated bile acids in cirrhotic patients , 1985, Hepatology.
[151] A. Hofmann,et al. Altered bile acid metabolism in primary biliary cirrhosis , 1981, Digestive Diseases and Sciences.
[152] G. Burckhardt,et al. Sodium-coupled taurocholate transport in the proximal convolution of the rat kidney in vivo and in vitro. , 1981, The Journal of clinical investigation.
[153] R. Vonk,et al. Lithocholate cholestasis—Sulfated glycolithocholate-induced intrahepatic cholestasis in rats , 1981 .
[154] J. Sjövall,et al. Hydroxylation of cholic, chenodeoxycholic, and deoxycholic acids in patients with intrahepatic cholestasis. , 1980, Journal of lipid research.
[155] J. Sjövall,et al. Analysis of bile acid glucuronides in urine. Identification of 3α,6α,12α-trihydroxy-5β-cholanoic acid , 1980 .
[156] M. Vore,et al. Characterization of cholestasis induced by estradiol-17 beta-D-glucuronide in the rat. , 1980, The Journal of pharmacology and experimental therapeutics.
[157] F. Schaffner,et al. Pericanalicular hepatocytic and bile ductular microfilaments in cholestasis in man. , 1980, The American journal of pathology.
[158] J. Boyer,et al. Chlorpromazine and its metabolites alter polymerization and gelation of actin. , 1979, Science.
[159] P. Thomassen. Urinary bile acids in late pregnancy and in recurrent cholestasis of pregnancy , 1979, European journal of clinical investigation.
[160] J. Sjövall,et al. Bile acid profiles in urine of patients with liver diseases , 1979, European journal of clinical investigation.
[161] J. Sjövall,et al. Analysis of metabolic profiles of bile acids in urine using a lipophilic anion exchanger and computerized gas-liquid chromatorgaphy-mass spectrometry. , 1977, Journal of lipid research.
[162] W. Fröhling,et al. [Morphologic studies on the toxicity of sulfated and nonsulfated lithocholic acid in the isolation-perfused rat liver]. , 1977, Zeitschrift fur Gastroenterologie.
[163] G. P. van Berge Henegouwen,et al. Sulphated and unsulphated bile acids in serum, bile, and urine of patients with cholestasis. , 1976, Gut.
[164] W. Fröhling. Bile Salt Glucuronides: Identification and Quantitative Analysis in the Urine of Patients with Cholestasis , 1976, European journal of clinical investigation.
[165] I. Makino,et al. Sulfated and nonsulfated bile acids in urine, serum, and bile of patients with hepatobiliary diseases. , 1975, Gastroenterology.
[166] J. Sjövall,et al. Steroid sulphates in plasma from pregnant women with pruritus and elevated plasma bile acid levels. , 1970, Annals of clinical research.
[167] S. Sookoian,et al. Association of the multidrug-resistance-associated protein gene (ABCC2) variants with intrahepatic cholestasis of pregnancy. , 2008, Journal of hepatology.
[168] H. Bernstein,et al. Bile acids as carcinogens in human gastrointestinal cancers. , 2005, Mutation research.
[169] M. Hiltunen,et al. Association of single nucleotide polymorphisms of the bile salt export pump gene with intrahepatic cholestasis of pregnancy. , 2003, Scandinavian journal of gastroenterology.
[170] K. Zatloukal,et al. Induction of short heterodimer partner 1 precedes downregulation of Ntcp in bile duct-ligated mice. , 2002, American journal of physiology. Gastrointestinal and liver physiology.
[171] Anand K. Srivastava,et al. Identification of a gene, ABCG5, important in the regulation of dietary cholesterol absorption , 2001, Nature Genetics.
[172] J. Boyer,et al. Molecular Alterations in Hepatocyte Transport Mechanisms in Acquired Cholestatic Liver Disorders , 2000, Seminars in liver disease.
[173] I. Arias,et al. Intracellular Trafficking and Regulation of Canalicular ATP-Binding Cassette Transporters , 2000, Seminars in liver disease.
[174] P. Meier,et al. Decreased Na+-dependent taurocholate uptake and low expression of the sinusoidal Na+-taurocholate cotransporting protein (Ntcp) in livers of mdr2 P-glycoprotein-deficient mice. , 1999, Journal of hepatology.
[175] R. W. Daniel,et al. Expression and transport properties of the human ileal and renal sodium-dependent bile acid transporter. , 1998, American journal of physiology. Gastrointestinal and liver physiology.
[176] R. Moseley. Sepsis-associated cholestasis. , 1997, Gastroenterology.
[177] V. Desmet. Vanishing bile duct syndrome in drug-induced liver disease. , 1997, Journal of hepatology.
[178] J. Boyer,et al. Down-regulation of expression and function of the rat liver Na+/bile acid cotransporter in extrahepatic cholestasis. , 1996, Gastroenterology.
[179] Y. Bacq,et al. Serum conjugated bile acid profile during intrahepatic cholestasis of pregnancy. , 1995, Journal of hepatology.
[180] V. McKusick,et al. Byler Disease: Fatal Familial Intrahepatic Cholestasis in an Amish Kindred , 1969 .