Regenerative effects of transplanting mesenchymal stem cells embedded in atelocollagen to the degenerated intervertebral disc.

[1]  Xiong Guo,et al.  Bone Mesenchymal Stem Cells Transplanted into Rabbit Intervertebral Discs Can Increase Proteoglycans , 2005, Clinical orthopaedics and related research.

[2]  T. Albert,et al.  Differentiation of Mesenchymal Stem Cells Towards a Nucleus Pulposus-like Phenotype In Vitro: Implications for Cell-Based Transplantation Therapy , 2004, Spine.

[3]  I. Yannas,et al.  Antigenicity and immunogenicity of collagen. , 2004, Journal of biomedical materials research. Part B, Applied biomaterials.

[4]  D. Sakai,et al.  Upregulation of the Viability of Nucleus Pulposus Cells by Bone Marrow-Derived Stromal Cells: Significance of Direct Cell-to-Cell Contact in Coculture System , 2004, Spine.

[5]  George M. Wahba,et al.  Intervertebral Disc Cell Therapy for Regeneration: Mesenchymal Stem Cell Implantation in Rat Intervertebral Discs , 2004, Annals of Biomedical Engineering.

[6]  W. Hutton,et al.  Disc Chondrocyte Transplantation in a Canine Model: A Treatment for Degenerated or Damaged Intervertebral Disc , 2003, Spine.

[7]  K. Ando,et al.  Transplantation of mesenchymal stem cells embedded in Atelocollagen gel to the intervertebral disc: a potential therapeutic model for disc degeneration. , 2003, Biomaterials.

[8]  D. Sakai,et al.  72. Reinsertion of nucleus pulposus cells activated by mesenchymal stem cells using coculture method decelerated intervertebral disc degeneration , 2003 .

[9]  Tong-Chuan He,et al.  Potential Use of Sox9 Gene Therapy for Intervertebral Degenerative Disc Disease , 2003, Spine.

[10]  R. Poulsom,et al.  The new stem cell biology: something for everyone , 2003, Molecular pathology : MP.

[11]  H. Gruber,et al.  Recent Advances in Disc Cell Biology , 2003, Spine.

[12]  H. Okano.  Stem cell biology of the central nervous system , 2002, Journal of neuroscience research.

[13]  H. Gruber,et al.  Autologous Intervertebral Disc Cell Implantation: A Model Using Psammomys obesus, the Sand Rat , 2002, Spine.

[14]  T. Albert,et al.  Comparative Gene Expression Profiling of Normal and Degenerative Discs: Analysis of a Rabbit Annular Laceration Model , 2002, Spine.

[15]  E. Thonar,et al.  Osteogenic protein-1 enhances matrix replenishment by intervertebral disc cells previously exposed to interleukin-1. , 2002, Spine.

[16]  J. Urban,et al.  Cells From Different Regions of the Intervertebral Disc: Effect of Culture System on Matrix Expression and Cell Phenotype , 2002, Spine.

[17]  H. Horner,et al.  2001 Volvo Award Winner in Basic Science Studies: Effect of Nutrient Supply on the Viability of Cells From the Nucleus Pulposus of the Intervertebral Disc , 2001, Spine.

[18]  J. Mochida,et al.  Nucleus Pulposus Allograft Retards Intervertebral Disc Degeneration , 2001, Clinical orthopaedics and related research.

[19]  Hilkka Riihimäki,et al.  Disc Height and Signal Intensity of the Nucleus Pulposus on Magnetic Resonance Imaging as Indicators of Lumbar Disc Degeneration , 2001, Spine.

[20]  G. Im,et al.  Repair of cartilage defect in the rabbit with cultured mesenchymal stem cells from bone marrow. , 2001, The Journal of bone and joint surgery. British volume.

[21]  Alan W. Flake,et al.  Human mesenchymal stem cells engraft and demonstrate site-specific differentiation after in utero transplantation in sheep , 2000, Nature Medicine.

[22]  J. Mochida,et al.  Reinsertion of stimulated nucleus pulposus cells retards intervertebral disc degeneration: An in vitro and in vivo experimental study , 2000, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[23]  H. Gruber,et al.  Human disc cells in monolayer vs 3D culture: cell shape, division and matrix formation , 2000, BMC musculoskeletal disorders.

[24]  R. Deans,et al.  Mesenchymal stem cells: biology and potential clinical uses. , 2000, Experimental hematology.

[25]  L G Gilbertson,et al.  Modulation of the biologic activity of the rabbit intervertebral disc by gene therapy: an in vivo study of adenovirus-mediated transfer of the human transforming growth factor beta 1 encoding gene. , 1999, Spine.

[26]  K. Ando,et al.  Rapid ex vivo expansion of human umbilical cord hematopoietic progenitors using a novel culture system. , 1999, Experimental hematology.

[27]  Darwin J. Prockop,et al.  Transplantability and therapeutic effects of bone marrow-derived mesenchymal cells in children with osteogenesis imperfecta , 1999, Nature Medicine.

[28]  S. Gerson.  Mesenchymal stem cells: No longer second class marrow citizens , 1999, Nature Medicine.

[29]  T. Oegema,et al.  Notochordal cells interact with nucleus pulposus cells: regulation of proteoglycan synthesis. , 1999, Experimental cell research.

[30]  James D. Kang,et al.  Adenovirus‐Mediated Gene Transfer to Nucleus Pulposus Cells: Implications for the Treatment of Intervertebral Disc Degeneration , 1998, Spine.

[31]  J. Mochida,et al.  Percutaneous Reinsertion of the Nucleus Pulposus: An Experimental Study , 1998, Spine.

[32]  H. Gruber,et al.  Characterization and phenotypic stability of human disc cells in vitro. , 1997, Matrix Biology.

[33]  A I Caplan,et al.  Principles of cartilage repair and regeneration. , 1997, Clinical orthopaedics and related research.

[34]  Arnold I. Caplan,et al.  Overview: Principles of Cartilage Repair and Regeneration , 1997 .

[35]  K. Kaneda,et al.  Effects of Chondroitinase ABC and Chymopapain on Spinal Motion Segment Biomechanics: An In Vivo Biomechanical, Radiologic, and Histologic Canine Study , 1997, Spine.

[36]  D. Prockop.  Marrow Stromal Cells as Stem Cells for Nonhematopoietic Tissues , 1997, Science.

[37]  M. Aebi,et al.  The human lumbar intervertebral disc: evidence for changes in the biosynthesis and denaturation of the extracellular matrix with growth, maturation, ageing, and degeneration. , 1996, The Journal of clinical investigation.

[38]  J A Buckwalter,et al.  Aging and degeneration of the human intervertebral disc. , 1995, Spine.

[39]  J. Kraemer.  Natural course and prognosis of intervertebral disc diseases. International Society for the Study of the Lumbar Spine Seattle, Washington, June 1994. , 1995, Spine.

[40]  Y. Kanegae,et al.  A simple and efficient method for purification of infectious recombinant adenovirus. , 1994, Japanese journal of medical science & biology.

[41]  Joseph M. Mansour,et al.  Mesenchymal Cell-Based Repair of Large Full Thickness Defects of Articular Cartilage , 1994 .

[42]  Arnold I. Caplan,et al.  Mesenchymal Stem Cells , 1991, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[43]  Frymoyer Jw,et al.  An overview of the incidences and costs of low back pain. , 1991 .

[44]  CASEY K. LEE,et al.  Accelerated Degeneration of the Segment Adjacent to a Lumbar Fusion , 1988, Spine.

[45]  Paul D. Kessler,et al.  Human Mesenchymal Stem Cells Differentiate to a Cardiomyocyte Phenotype in the Adult Murine Heart , 2002, Circulation.

[46]  K. Kraus,et al.  Fluorescently labeled mesenchymal stem cells (MSCs) maintain multilineage potential and can be detected following implantation into articular cartilage defects. , 2002, Biomaterials.

[47]  A I Caplan,et al.  Characterization of cells with osteogenic potential from human marrow. , 1992, Bone.