Optical mass sensing with coupled nanomechanical resonator systems

In this paper, we focus on a particular application of the nanomechanical resonator: mass sensing in all-optical domain. Convectional mass detection is usually based on the electrical environment, where nanomechanical resonator should be suspended between two electrodes above a conducting plate, while a voltage applies on them. However, the heating effect and the energy loss induced by the voltage during the measurement will lead to the imprecision of mass sensing. In order to solve this problem, we propose an ultrasensitive optical scheme to weigh the external particles deposited onto the surface of the nanomechanical resonator via all-optical methods. This optical mass sensing has the potential to break through the limitation of frequency restriction and the sensitivity of mass sensing.

[1]  Kerry J. Vahala,et al.  Coherent mixing of mechanical excitations in nano-optomechanical structures , 2009, 0908.1128.

[2]  Laser cooling of a nanomechanical resonator mode to its quantum ground state. , 2003, Physical review letters.

[3]  M. Roukes,et al.  Ultimate limits to inertial mass sensing based upon nanoelectromechanical systems , 2003, physics/0309075.

[4]  A. Zrenner,et al.  Coherent properties of a two-level system based on a quantum-dot photodiode , 2002, Nature.

[5]  R. Aebersold,et al.  Mass Spectrometry and Protein Analysis , 2006, Science.

[6]  M. Roukes,et al.  Toward single-molecule nanomechanical mass spectrometry , 2005, Nature nanotechnology.

[7]  C. C. Wang,et al.  Nonlinear optics. , 1966, Applied optics.

[8]  Lin Tian,et al.  Storing optical information as a mechanical excitation in a silica optomechanical resonator. , 2011, Physical review letters.

[9]  M. Roukes Nanoelectromechanical systems face the future , 2001 .

[10]  A. Bachtold,et al.  Ultrasensitive mass sensing with a nanotube electromechanical resonator. , 2008, Nano letters.

[11]  M. Roukes,et al.  Zeptogram-scale nanomechanical mass sensing. , 2005, Nano letters.

[12]  S. Manalis,et al.  Weighing of biomolecules, single cells and single nanoparticles in fluid , 2007, Nature.

[13]  T. Alegre Electromagnetically Induced Transparency and Slow Light with Optomechanics , 2012 .

[14]  Michael L. Roukes,et al.  Putting mechanics into quantum mechanics , 2005 .

[15]  Ling Hao,et al.  Circuit cavity electromechanics in the strong-coupling regime , 2014 .

[16]  P. Skyba Notes on Measurement Methods of Mechanical Resonators Used in Low Temperature Physics , 2010 .

[17]  E. W. McDaniel,et al.  Electrospray Ion Source. Another Variation on the Free-Jet Theme , 1984 .

[18]  M. Bichler,et al.  Quantum optical properties of a single In x Ga 1 − x As − Ga As quantum dot two-level system , 2005 .

[19]  H. Postma,et al.  Atomic-scale mass sensing using carbon nanotube resonators. , 2008, Nano letters.

[20]  S. Deleglise,et al.  Optomechanically Induced Transparency , 2011 .

[21]  M. Blencowe Nanoelectromechanical systems , 2005, cond-mat/0502566.

[22]  A. Clerk,et al.  Strong electromechanical coupling of an atomic force microscope cantilever to a quantum dot. , 2010, Physical review letters.

[23]  M. Roukes,et al.  Ultrasensitive nanoelectromechanical mass detection , 2004, cond-mat/0402528.

[24]  Keith Aubin,et al.  Prion protein detection using nanomechanical resonator arrays and secondary mass labeling. , 2008, Analytical chemistry.

[25]  R. Aebersold,et al.  Mass spectrometry-based proteomics , 2003, Nature.

[26]  M. Mann,et al.  Electrospray Ionization for Mass Spectrometry of Large Biomolecules , 1990 .

[27]  Anja Boisen,et al.  Nanoelectromechanical systems: Mass spec goes nanomechanical. , 2009, Nature nanotechnology.

[28]  K. Jensen,et al.  An atomic-resolution nanomechanical mass sensor. , 2008, Nature Nanotechnology.

[29]  J. Chaste,et al.  A nanomechanical mass sensor with yoctogram resolution. , 2012, Nature nanotechnology.