P Endothelial Dysfunction Endothelial Dysfunction Induced by PostPrandial Lipemia Complete Protection Afforded by High-Intensity Aerobic Interval Exercise

Results Before the HFM, initial brachial artery diameters were similar in all trials (0.43 0.04 cm), but after the HFM, basal diameter decreased only in the control (0.39 0.03 cm) and CME (0.38 0.04 cm) trials. Before the HFM, FMD/shear was improved by a single bout of CME ( 20%, p 0.01) and HIIE ( 45%, p 0.01; group differences, p 0.01), with no effect in the control trial. After the HFM (30, 120, and 240 min), FMD decayed to a lesser extent with CME, but in a similar fashion to the control trial. In contrast, FMD in the HIIE trial remained elevated following the exercise despite a clear meal-induced lipemia. Although there were no correlations between vascular function and food-induced markers of cardiovascular risk, antioxidant status was strongly correlated with FMD (r 0.9, p 0.001).

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