High dose and long-term statin therapy accelerate coronary artery calcification.

[1]  M. Budoff,et al.  Impact of coronary artery calcium on coronary heart disease events in individuals at the extremes of traditional risk factor burden: the Multi-Ethnic Study of Atherosclerosis. , 2014, European heart journal.

[2]  Jennifer G. Robinson,et al.  2013 ACC/AHA Guideline on the Assessment of Cardiovascular Risk: A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines , 2014, Circulation.

[3]  P. Libby,et al.  Long-term effects of maximally intensive statin therapy on changes in coronary atheroma composition: insights from SATURN. , 2014, European heart journal cardiovascular Imaging.

[4]  L. C. Pôrto,et al.  Oxidative Stress and Inflammation Are Differentially Affected by Atorvastatin, Pravastatin, Rosuvastatin, and Simvastatin on Lungs from Mice Exposed to Cigarette Smoke , 2014, Inflammation.

[5]  D. Grönemeyer,et al.  Effect of smoking and other traditional risk factors on the onset of coronary artery calcification: results of the Heinz Nixdorf recall study. , 2014, Atherosclerosis.

[6]  M. Drazner,et al.  2013 ACCF/AHA guideline for the management of heart failure: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. , 2013, Journal of the American College of Cardiology.

[7]  E. Aikawa,et al.  Role of Extracellular Vesicles in De Novo Mineralization: An Additional Novel Mechanism of Cardiovascular Calcification , 2013, Arteriosclerosis, thrombosis, and vascular biology.

[8]  K. Takazawa,et al.  Plaque stabilization by intensive LDL-cholesterol lowering therapy with atorvastatin is delayed in type 2 diabetic patients with coronary artery disease-Serial angioscopic and intravascular ultrasound analysis. , 2013, Journal of cardiology.

[9]  R. Kronmal,et al.  Progression of coronary calcium and incident coronary heart disease events: MESA (Multi-Ethnic Study of Atherosclerosis). , 2013, Journal of the American College of Cardiology.

[10]  M. Budoff,et al.  Impact of coronary artery calcium progression and statin therapy on clinical outcome in subjects with and without diabetes mellitus. , 2013, The American journal of cardiology.

[11]  Michael C. McDaniel,et al.  Effect of intensive atorvastatin therapy on coronary atherosclerosis progression, composition, arterial remodeling, and microvascular function. , 2012, The Journal of invasive cardiology.

[12]  M. Henein,et al.  The nature of cardiac calcification in aortic stenosis. , 2012, International journal of cardiology.

[13]  M. Budoff,et al.  Improvement of cardiovascular risk prediction using coronary imaging: subclinical atherosclerosis: the memory of lifetime risk factor exposure. , 2012, European heart journal.

[14]  M. Budoff,et al.  Very small calcifications are detected and scored in the coronary arteries from small voxel MDCT images using a new automated/calibrated scoring method with statistical and patient specific plaque definitions , 2012, The International Journal of Cardiovascular Imaging.

[15]  M. Henein,et al.  Statins moderate coronary stenoses but not coronary calcification: results from meta-analyses. , 2011, International journal of cardiology.

[16]  Zahi A Fayad,et al.  2010 ACCF/AHA guideline for assessment of cardiovascular risk in asymptomatic adults: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. , 2010, Circulation.

[17]  Zahi A Fayad,et al.  2010 ACCF/AHA guideline for assessment of cardiovascular risk in asymptomatic adults: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. , 2010, Journal of the American College of Cardiology.

[18]  Daniel S Berman,et al.  Progression of coronary artery calcium predicts all-cause mortality. , 2010, JACC. Cardiovascular imaging.

[19]  S. Moebus,et al.  Subclinical coronary atherosclerosis and resting ECG abnormalities in an unselected general population. , 2008, Atherosclerosis.

[20]  J. Deanfield,et al.  Childhood origins of arterial disease , 2007, Current opinion in pediatrics.

[21]  T. Morgan,et al.  Effect of simvastatin (80 mg) on coronary and abdominal aortic arterial calcium (from the coronary artery calcification treatment with zocor [CATZ] study). , 2007, The American journal of cardiology.

[22]  Jonathan G Goldin,et al.  Assessment of Coronary Artery Disease by Cardiac Computed Tomography: A Scientific Statement From the American Heart Association Committee on Cardiovascular Imaging and Intervention, Council on Cardiovascular Radiology and Intervention, and Committee on Cardiac Imaging, Council on Clinical Cardiolog , 2006, Circulation.

[23]  R. Prescott,et al.  Progressive coronary calcification despite intensive lipid-lowering treatment: a randomised controlled trial , 2006, Heart.

[24]  S. Achenbach,et al.  Effect of Intensive Versus Standard Lipid-Lowering Treatment With Atorvastatin on the Progression of Calcified Coronary Atherosclerosis Over 12 Months: A Multicenter, Randomized, Double-Blind Trial , 2006, Circulation.

[25]  T. Callister,et al.  Aggressive Versus Moderate Lipid-Lowering Therapy in Hypercholesterolemic Postmenopausal Women: Beyond Endorsed Lipid Lowering With EBT Scanning (BELLES) , 2005, Circulation.

[26]  Y. Arad,et al.  Treatment of asymptomatic adults with elevated coronary calcium scores with atorvastatin, vitamin C, and vitamin E: the St. Francis Heart Study randomized clinical trial. , 2005, Journal of the American College of Cardiology.

[27]  Y. Arad,et al.  Objectives Background Methods Results Conclusions , 2022 .

[28]  M. Budoff,et al.  Progression of Coronary Artery Calcium and Occurrence of Myocardial Infarction in Patients With and Without Diabetes Mellitus , 2005, Hypertension.

[29]  E. Mohler,et al.  Paradoxical Effects of Statins on Aortic Valve Myofibroblasts and Osteoblasts: Implications for End-Stage Valvular Heart Disease , 2005, Arteriosclerosis, thrombosis, and vascular biology.

[30]  T. Callister,et al.  Progression of Coronary Artery Calcium and Risk of First Myocardial Infarction in Patients Receiving Cholesterol-Lowering Therapy , 2004, Arteriosclerosis, thrombosis, and vascular biology.

[31]  M. Budoff,et al.  Progression of coronary calcium on serial electron beam tomographic scanning is greater in patients with future myocardial infarction. , 2003, The American journal of cardiology.

[32]  S. Achenbach,et al.  Influence of Lipid-Lowering Therapy on the Progression of Coronary Artery Calcification: A Prospective Evaluation , 2002, Circulation.

[33]  J. Beckman,et al.  Relationship of Clinical Presentation and Calcification of Culprit Coronary Artery Stenoses , 2001, Arteriosclerosis, thrombosis, and vascular biology.

[34]  K R Maravilla,et al.  Effects of Prolonged Intensive Lipid-Lowering Therapy on the Characteristics of Carotid Atherosclerotic Plaques In Vivo by MRI: A Case-Control Study , 2001, Arteriosclerosis, thrombosis, and vascular biology.

[35]  T. Callister,et al.  Effect of HMG-CoA reductase inhibitors on coronary artery disease as assessed by electron-beam computed tomography. , 1998, The New England journal of medicine.

[36]  J. Badimón,et al.  Atherosclerotic plaque rupture and thrombosis. Evolving concepts. , 1990, Circulation.

[37]  R. Detrano,et al.  Quantification of coronary artery calcium using ultrafast computed tomography. , 1990, Journal of the American College of Cardiology.