Cell Expression of Inflammatory Cytokines CD 40 / CD 154 Blockade Inhibits Dendritic

[1]  K. Reimann,et al.  CD40 Blockade Combines with CTLA4Ig and Sirolimus to Produce Mixed Chimerism in an MHC‐Defined Rhesus Macaque Transplant Model , 2012, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[2]  Sunmi Yang,et al.  Critical Role of Proinflammatory Cytokine IL‐6 in Allograft Rejection and Tolerance , 2012, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[3]  B. Burrell,et al.  IL-6 Promotes Cardiac Graft Rejection Mediated by CD4+ Cells , 2011, The Journal of Immunology.

[4]  A. Kirk,et al.  CD40‐Specific Costimulation Blockade Enhances Neonatal Porcine Islet Survival in Nonhuman Primates , 2011, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[5]  C. Ruedl,et al.  Cutting Edge: Granulocyte-Macrophage Colony-Stimulating Factor Is the Major CD8+ T Cell-Derived Licensing Factor for Dendritic Cell Activation , 2010, The Journal of Immunology.

[6]  Z. Milas,et al.  Anti-CD40 Monoclonal Antibody Synergizes with CTLA4-Ig in Promoting Long-Term Graft Survival in Murine Models of Transplantation , 2009, The Journal of Immunology.

[7]  E. Ahmed,et al.  TLR Signals Promote IL-6/IL-17-Dependent Transplant Rejection1 , 2009, The Journal of Immunology.

[8]  D. Goldstein,et al.  IL-6 and TNF-alpha synergistically inhibit allograft acceptance. , 2009, Journal of the American Society of Nephrology : JASN.

[9]  Nikhil S. Joshi,et al.  Inflammation directs memory precursor and short-lived effector CD8(+) T cell fates via the graded expression of T-bet transcription factor. , 2007, Immunity.

[10]  H. Weiner,et al.  Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells , 2006, Nature.

[11]  S. Anderton,et al.  Kinetics of costimulatory molecule expression by T cells and dendritic cells during the induction of tolerance versus immunity in vivo , 2005, European journal of immunology.

[12]  N. Kenyon,et al.  Development of a Chimeric Anti-CD40 Monoclonal Antibody That Synergizes with LEA29Y to Prolong Islet Allograft Survival1 , 2005, The Journal of Immunology.

[13]  J. Curtsinger,et al.  CD8 T Cell Clonal Expansion and Development of Effector Function Require Prolonged Exposure to Antigen, Costimulation, and Signal 3 Cytokine 1 , 2003, The Journal of Immunology.

[14]  E. Ingulli,et al.  Development of a Novel Transgenic Mouse for the Study of Interactions Between CD4 and CD8 T Cells During Graft Rejection , 2003, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[15]  W. Hörl,et al.  Prevention of CD40‐Triggered Dendritic Cell Maturation and Induction of T‐Cell Hyporeactivity by Targeting of Janus Kinase 3 , 2003, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[16]  E. Simpson,et al.  Fc-dependent depletion of activated T cells occurs through CD40L-specific antibody rather than costimulation blockade , 2003, Nature Medicine.

[17]  C. Hunter,et al.  TRAF6 is a critical factor for dendritic cell maturation and development. , 2003, Immunity.

[18]  J. Curtsinger,et al.  Signal 3 Determines Tolerance versus Full Activation of Naive CD8 T Cells , 2003, The Journal of experimental medicine.

[19]  J. Ringers,et al.  Prevention of kidney allograft rejection using anti-CD40 and anti-CD86 in primates , 2003, Transplantation.

[20]  M. Jenkins,et al.  Dendritic cell longevity and T cell persistence is controlled by CD154‐CD40 interactions , 2001, European journal of immunology.

[21]  R. Colvin,et al.  Thromboembolic complications after treatment with monoclonal antibody against CD40 ligand. , 2000, Nature medicine.

[22]  R. Colvin,et al.  Thromboembolic complications after treatment with monoclonal antibody against CD40 ligand , 2000, Nature Medicine.

[23]  J. Banchereau,et al.  CD40‐CD40 ligand , 2000, Journal of leukocyte biology.

[24]  M. Bachmann,et al.  CD8+ T Cells Mediate CD40-independent Maturation of Dendritic Cells In Vivo , 1999, The Journal of experimental medicine.

[25]  D. Harlan,et al.  Treatment with humanized monoclonal antibody against CD154 prevents acute renal allograft rejection in nonhuman primates , 1999, Nature Medicine.

[26]  M. Jenkins,et al.  Inflammatory cytokines provide a third signal for activation of naive CD4+ and CD8+ T cells. , 1999, Journal of immunology.

[27]  M. Moser,et al.  Antigen-specific T lymphocytes regulate lipopolysaccharide-induced apoptosis of dendritic cells in vivo. , 1998, Journal of immunology.

[28]  Richard A. Flavell,et al.  Help for cytotoxic-T-cell responses is mediated by CD40 signalling , 1998, Nature.

[29]  Stephen P. Schoenberger,et al.  T-cell help for cytotoxic T lymphocytes is mediated by CD40–CD40L interactions , 1998, Nature.

[30]  Polly Matzinger,et al.  A conditioned dendritic cell can be a temporal bridge between a CD4+ T-helper and a T-killer cell , 1998, Nature.

[31]  R. Noelle,et al.  Long-term survival of skin allografts induced by donor splenocytes and anti-CD154 antibody in thymectomized mice requires CD4(+) T cells, interferon-gamma, and CTLA4. , 1998, The Journal of clinical investigation.

[32]  R. Steinman,et al.  Dendritic cells and the control of immunity , 1998, Nature.

[33]  D. Harlan,et al.  CTLA4-Ig and anti-CD40 ligand prevent renal allograft rejection in primates. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[34]  P. Linsley,et al.  Costimulatory function and expression of CD40 ligand, CD80, and CD86 in vascularized murine cardiac allograft rejection. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[35]  P. Linsley,et al.  Long-term acceptance of skin and cardiac allografts after blocking CD40 and CD28 pathways , 1996, Nature.

[36]  大浦 哲 Long-term hepatic allograft acceptance based on CD40 blockade by ASKP1240 in nonhuman primates , 2012 .

[37]  C Caux,et al.  Immunobiology of dendritic cells. , 2000, Annual review of immunology.