Evidence for a differential opioidergic involvement in the analgesic effect of antidepressants: prediction for efficacy in animal models of neuropathic pain?

Antidepressants are one of the recommended treatments for neuropathic pain. However, their analgesic action remains unpredictable, and there are no selection criteria for clinical use. Better knowledge of their mechanism of action could help highlight differences underlying their unequal efficacy.

[1]  武田 龍一郎 Analgesic effect of milnacipran is associated with c-Fos expression in the anterior cingulate cortex in the rat neuropathic pain model , 2010 .

[2]  P. L. McCormack,et al.  Duloxetine: a review of its use in the treatment of generalized anxiety disorder. , 2009, CNS drugs.

[3]  T. Mashimo,et al.  Antiallodynic and Antihyperalgesic Effect of Milnacipran in Mice with Spinal Nerve Ligation , 2008, Anesthesia and analgesia.

[4]  Aytül Önal,et al.  Milnacipran attenuates hyperalgesia and potentiates antihyperalgesic effect of tramadol in rats with mononeuropathic pain , 2007, Pharmacology Biochemistry and Behavior.

[5]  J. Farrar,et al.  Pharmacologic management of neuropathic pain: Evidence-based recommendations , 2007, PAIN.

[6]  A. Eschalier,et al.  Behavioral and pharmacological description of oxaliplatin-induced painful neuropathy in rat , 2007, PAIN.

[7]  M. Rowbotham,et al.  Duloxetine for the management of diabetic peripheral neuropathic pain: evidence-based findings from post hoc analysis of three multicenter, randomized, double-blind, placebo-controlled, parallel-group studies. , 2007, Clinical therapeutics.

[8]  T. Vanderah,et al.  Differential blockade of nerve injury-induced shift in weight bearing and thermal and tactile hypersensitivity by milnacipran. , 2006, The journal of pain : official journal of the American Pain Society.

[9]  A. Eschalier,et al.  Antidepressants and pain. , 2006, Trends in pharmacological sciences.

[10]  W. Cayley Antidepressants for the treatment of neuropathic pain. , 2006, American family physician.

[11]  H. Obata,et al.  The Monoamine-Mediated Antiallodynic Effects of Intrathecally Administered Milnacipran, a Serotonin Noradrenaline Reuptake Inhibitor, in a Rat Model of Neuropathic Pain , 2005, Anesthesia and analgesia.

[12]  J. Mikkelsen,et al.  Antinociceptive effects of the antidepressants amitriptyline, duloxetine, mirtazapine and citalopram in animal models of acute, persistent and neuropathic pain , 2005, Neuropharmacology.

[13]  N. B. Finnerupa,et al.  Algorithm for neuropathic pain treatment: An evidence based proposal , 2005 .

[14]  S. Iyengar,et al.  Efficacy of Duloxetine, a Potent and Balanced Serotonin-Norepinephrine Reuptake Inhibitor in Persistent Pain Models in Rats , 2004, Journal of Pharmacology and Experimental Therapeutics.

[15]  I. Takasaki,et al.  Effects of the suppression of acute herpetic pain by gabapentin and amitriptyline on the incidence of delayed postherpetic pain in mice. , 2004, Life sciences.

[16]  D. Jourdan,et al.  Evidence for an Involvement of Supraspinal δ- and Spinal μ-Opioid Receptors in the Antihyperalgesic Effect of Chronically Administered Clomipramine in Mononeuropathic Rats , 2003, Journal of Pharmacology and Experimental Therapeutics.

[17]  A. Eschalier,et al.  The antihyperalgesic effect of venlafaxine in diabetic rats does not involve the opioid system , 2003, Neuroscience Letters.

[18]  F. Marchanda,et al.  JPET # 52613 1 Evidence for an involvement of supraspinal delta and spinal mu opioid receptors in the antihyperalgesic effect of chronically administered clomipramine in mononeuropathic rats , 2003 .

[19]  R. Tsujita,et al.  Neurochemical and behavioural characterization of milnacipran, a serotonin and noradrenaline reuptake inhibitor in rats , 2002, Psychopharmacology.

[20]  N. Miki,et al.  Repeated administration of milnacipran induces rapid desensitization of somatodendritic 5-HT1A autoreceptors but not postsynaptic 5-HT1A receptors , 2002, Journal of psychopharmacology.

[21]  R. Przewłocki,et al.  Opioids in chronic pain. , 2001, European journal of pharmacology.

[22]  A. Eschalier,et al.  Potentiation of morphine and clomipramine analgesia by cholecystokinin -B antagonist CI-988 in diabetic rats , 2000, Neuroscience Letters.

[23]  A. Eschalier,et al.  [Analgesics. Utilization principles and rules, posology of morphine and its derivatives]. , 2000, La Revue du praticien.

[24]  R. Lipton,et al.  Towards a mechanism-based classification of pain? , 1998, Pain.

[25]  M. Briley,et al.  Lack of Effect of Repeated Administration of Milnacipran, a Double Noradrenaline and Serotonin Reuptake Inhibitor, on the β-adrenoceptor-linked Adenylate Cyclase System in the Rat Cerebral Cortex , 1996, Neuropharmacology.

[26]  A. Eschalier,et al.  Study of the sensitivity of the diabetes-induced pain model in rats to a range of analgesics , 1994, Pain.

[27]  A. Eschalier,et al.  Streptozocin-induced diabetic rats: behavioural evidence for a model of chronic pain , 1993, Pain.

[28]  D. Ardid,et al.  Antinociceptive effects of acute and ‘chronic’ injections of tricyclic antidepressant drugs in a new model of mononeuropathy in rats , 1992, Pain.

[29]  H. Beck-Nielsen,et al.  Clomipramine vs desipramine vs placebo in the treatment of diabetic neuropathy symptoms. A double-blind cross-over study. , 1990, British journal of clinical pharmacology.

[30]  A. Eschalier [Analgesics of the morphine type (and their antagonists)]. , 1990, La Revue du praticien.

[31]  A. Eschalier,et al.  Pharmacokinetic patterns of repeated administration of antidepressants in animals. I. Implications for antinociceptive action of clomipramine in mice. , 1988, The Journal of pharmacology and experimental therapeutics.

[32]  Gary J. Bennett,et al.  A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man , 1988, Pain.

[33]  P. Mantegazza,et al.  Autotomy and central nervous system neuropeptides after section of the sciatic nerve in rats of different strains , 1987, Pharmacology Biochemistry and Behavior.

[34]  P. Mantegazza,et al.  A role for serotonin and beta-endorphin in the analgesia induced by some tricyclic antidepressant drugs , 1987, Pharmacology Biochemistry and Behavior.

[35]  M. Lewis,et al.  Streptozocin Diabetes Alters Immunoreactive β-Endorphin Levels and Pain Perception After 8 wk in Female Rats , 1986, Diabetes.

[36]  K. Isenberg,et al.  Possible involvement of opiate receptors in the pharmacological profiles of antidepressant compounds. , 1984, European journal of pharmacology.

[37]  M. Zimmermann,et al.  Ethical guidelines for investigations of experimental pain in conscious animals , 1983, Pain.

[38]  H. Fields,et al.  Amitriptyline potentiates morphine analgesia by a direct action on the central nervous system , 1983, Annals of Neurology.

[39]  M. Stöhr,et al.  An open and double-blind cross-over study on the efficacy of clomipramine (Anafranil) in patients with painful mono- and polyneuropathies. , 1982, European Neurology.

[40]  R. Lo,et al.  A method for measurement of analgesic activity on inflamed tissue. , 1957 .

[41]  L. O. Randall,et al.  A method for measurement of analgesic activity on inflamed tissue. , 1957, Archives internationales de pharmacodynamie et de therapie.