Quantitative Determination of Kurarinone and Trifolirhizin from the Roots of Sophora flavescens

A simple reversed phase HPLC method was developed for extracting pharmacologically active compounds kurarinone and trifolirhizin from the roots of Sophora flavescens using a binary gradient of acetonitrile : with UV detection at 254 nm. The kurarinone and trifolirhizin contents of the roots of S. flavescens collected from ten district markets in Korea and China were and , respectively.

[1]  S. Xiong,et al.  Novel antitumor activities of Kushen flavonoids In Vitro and In Vivo , 2007, Phytotherapy research : PTR.

[2]  Jeong-Hill Park,et al.  Identification and characterization of antioxidants from Sophora flavescens. , 2006, Biological & pharmaceutical bulletin.

[3]  Yu-Ling Huang,et al.  Phenolic constituents of the roots of Sophora flavescens. , 2006, Journal of natural products.

[4]  Jiang Li,et al.  Matrine improves 2,4,6-trinitrobenzene sulfonic acid-induced colitis in mice. , 2006, Pharmacological research.

[5]  K. Park,et al.  Glycosidase inhibitory flavonoids from Sophora flavescens. , 2006, Biological & pharmaceutical bulletin.

[6]  H. Ha,et al.  High performance liquid chromatographic analysis of isoflavones in medicinal herbs , 2006, Archives of pharmacal research.

[7]  J. Choi,et al.  In Vitro Free Radical and ONOO- Scavengers from Sophora flavescens , 2005, Archives of pharmacal research.

[8]  G. Haegeman,et al.  Estrogenic and anticarcinogenic properties of kurarinone, a lavandulyl flavanone from the roots of Sophora flavescens. , 2004, Journal of natural products.

[9]  Huajuan Wang,et al.  Simultaneous determination of matrine, sophoridine and oxymatrine in Sophora flavescens Ait. by high performance liquid chromatography. , 2004, Biomedical chromatography : BMC.

[10]  Jin-Kyu Park,et al.  Quantitative Determination of Triterpenoids from the Fruits of Zizyphus jujuba , 2004 .

[11]  H. Kim,et al.  A new prenylated flavonol from the roots of Sophora flavescens. , 1998, Journal of natural products.