Online risk engines and scoring tools in endocrinology

With evolution of evidence-based medicine, risk prediction equations have been formulated and validated. Such risk engines and scoring systems are able to predict disease outcome and risks of possible complications with varying degrees of accuracy. From health policy makers point of view it helps in appropriate disbursement of available resources for greatest benefit of population at risk. Understandably, the accuracy of prediction of different risk engines and scoring systems are highly variable and has several limitations. Each risk engine or clinical scoring tool is derived from data obtained from a particular population and its results are not generalizable and hence its ability to predict risk/outcome in a different population with differences in ethnicity, ages, and differences in distribution of risk factors over time both within and between populations. These scoring systems and risk engines to begin with were available for manual calculations and references/use of formula and paper charts were essential. However, with evolution of information technology such calculations became easier to make with use of online web-based tools. In recent times with advancement of android technology, easy to download apps (applications) has helped further to have the benefits of these online risk engines and scoring systems at our finger tips.

[1]  M. Pencina,et al.  General Cardiovascular Risk Profile for Use in Primary Care: The Framingham Heart Study , 2008, Circulation.

[2]  T. Therneau,et al.  The NAFLD fibrosis score: A noninvasive system that identifies liver fibrosis in patients with NAFLD , 2007, Hepatology.

[3]  R. R. Holman,et al.  UKPDS Outcomes Model 2: a new version of a model to simulate lifetime health outcomes of patients with type 2 diabetes mellitus using data from the 30 year United Kingdom Prospective Diabetes Study: UKPDS 82 , 2013, Diabetologia.

[4]  Carol Coupland,et al.  Derivation and validation of updated QFracture algorithm to predict risk of osteoporotic fracture in primary care in the United Kingdom: prospective open cohort study , 2012, BMJ : British Medical Journal.

[5]  M. Vanderpump,et al.  An objective scoring tool in the management of patients with pituitary apoplexy , 2011, Clinical endocrinology.

[6]  E. Bergstralh,et al.  Predicting outcome in papillary thyroid carcinoma: development of a reliable prognostic scoring system in a cohort of 1779 patients surgically treated at one institution during 1940 through 1989. , 1993, Surgery.

[7]  B. O'Sullivan,et al.  A comparison of different staging systems predictability of patient outcome , 1997, Cancer.

[8]  F. Péter,et al.  Congenital disorders of the thyroid: hypo/hyper. , 2011, Pediatric clinics of North America.

[9]  J. Tijssen,et al.  Prediction of progression to overt hypothyroidism or hyperthyroidism in female relatives of patients with autoimmune thyroid disease using the Thyroid Events Amsterdam (THEA) score. , 2008, Archives of internal medicine.

[10]  D. Levy,et al.  Prediction of coronary heart disease using risk factor categories. , 1998, Circulation.

[11]  E. Siris,et al.  Primary Care Use of FRAX®: Absolute Fracture Risk Assessment in Postmenopausal Women and Older Men , 2010, Postgraduate medicine.

[12]  Eugene McCloskey,et al.  FRAX and its applications to clinical practice. , 2009, Bone.

[13]  Nicholas J. Wareham,et al.  Performance of the UK Prospective Diabetes Study Risk Engine and the Framingham Risk Equations in Estimating Cardiovascular Disease in the EPIC- Norfolk Cohort , 2008, Diabetes Care.

[14]  W. Wiersinga,et al.  Clinical activity score as a guide in the management of patients with Graves' ophthalmopathy , 1997, Clinical endocrinology.

[15]  G. Rose Clinical activity score as a guide in the management of patients with Graves' orbitopathy , 1997, Clinical endocrinology.

[16]  H. Tunstall-Pedoe,et al.  Estimation of ten-year risk of fatal cardiovascular disease in Europe: the SCORE project. , 2003, European heart journal.

[17]  G. Zettinig,et al.  Application of Staging Systems for Differentiated Thyroid Carcinoma in an Endemic Goiter Region With Iodine Substitution , 2003, Annals of surgery.