IAPs: what's in a name?
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[1] Shaomeng Wang,et al. Design and characterization of bivalent Smac-based peptides as antagonists of XIAP and development and validation of a fluorescence polarization assay for XIAP containing both BIR2 and BIR3 domains. , 2008, Analytical biochemistry.
[2] W. Sellers,et al. A Smac mimetic rescue screen reveals roles for inhibitor of apoptosis proteins in tumor necrosis factor-alpha signaling. , 2007, Cancer research.
[3] A. Goldberg,et al. c-IAP1 cooperates with Myc by acting as a ubiquitin ligase for Mad1. , 2007, Molecular cell.
[4] David L. Vaux,et al. IAP Antagonists Target cIAP1 to Induce TNFα-Dependent Apoptosis , 2007, Cell.
[5] Seda Çöl Arslan,et al. Malt1 ubiquitination triggers NF‐κB signaling upon T‐cell activation , 2007 .
[6] J. Minna,et al. Autocrine TNFalpha signaling renders human cancer cells susceptible to Smac-mimetic-induced apoptosis. , 2007, Cancer cell.
[7] J. Reed,et al. Birc2 (cIap1) regulates endothelial cell integrity and blood vessel homeostasis , 2007, Nature Genetics.
[8] C. Duckett,et al. Apoptosis-Inducing Factor Is a Target for Ubiquitination through Interaction with XIAP , 2007, Molecular and Cellular Biology.
[9] R. Korneluk,et al. Degradation of Survivin by the X-linked Inhibitor of Apoptosis (XIAP)-XAF1 Complex* , 2007, Journal of Biological Chemistry.
[10] S. Fulda. Inhibitor of apoptosis proteins as targets for anticancer therapy , 2007, Expert review of anticancer therapy.
[11] L. Bruhn,et al. Promiscuous mutations activate the noncanonical NF-kappaB pathway in multiple myeloma. , 2007, Cancer cell.
[12] H. Inagaki. Mucosa‐associated lymphoid tissue lymphoma: Molecular pathogenesis and clinicopathological significance , 2007, Pathology international.
[13] U. Klein,et al. Structure of a Survivin–Borealin–INCENP Core Complex Reveals How Chromosomal Passengers Travel Together , 2007, Cell.
[14] R. Korneluk,et al. The inhibitors of apoptosis (IAPs) as cancer targets , 2007, Apoptosis.
[15] Jiahuai Han,et al. XIAP induces NF-kappaB activation via the BIR1/TAB1 interaction and BIR1 dimerization. , 2007, Molecular cell.
[16] R. Korneluk,et al. The role of XAF1 in cancer. , 2007, Current opinion in investigational drugs.
[17] M. Duffy,et al. Survivin: a promising tumor biomarker. , 2007, Cancer letters.
[18] Michael Dourson,et al. Copper and Human Health: Biochemistry, Genetics, and Strategies for Modeling Dose-response Relationships , 2007, Journal of toxicology and environmental health. Part B, Critical reviews.
[19] Yongge Zhao,et al. Tumor Necrosis Factor Receptor 2 Signaling Induces Selective c-IAP1-dependent ASK1 Ubiquitination and Terminates Mitogen-activated Protein Kinase Signaling* , 2007, Journal of Biological Chemistry.
[20] J. Seol,et al. The Drosophila Inhibitor of Apoptosis (IAP) DIAP2 Is Dispensable for Cell Survival, Required for the Innate Immune Response to Gram-negative Bacterial Infection, and Can Be Negatively Regulated by the Reaper/Hid/Grim Family of IAP-binding Apoptosis Inducers* , 2007, Journal of Biological Chemistry.
[21] D. Altieri. The case for survivin as a regulator of microtubule dynamics and cell-death decisions. , 2006, Current opinion in cell biology.
[22] R. Medema,et al. The case for Survivin as mitotic regulator. , 2006, Current opinion in cell biology.
[23] F. Rieux-Laucat,et al. XIAP deficiency in humans causes an X-linked lymphoproliferative syndrome , 2006, Nature.
[24] V. Dixit,et al. The Inhibitor of Apoptosis Protein Fusion c-IAP2·MALT1 Stimulates NF-κB Activation Independently of TRAF1 AND TRAF2* , 2006, Journal of Biological Chemistry.
[25] E. D. de Vries,et al. The clinical trail of TRAIL. , 2006, European journal of cancer.
[26] Masatomo Kobayashi,et al. Drosophila IKK-Related Kinase Regulates Nonapoptotic Function of Caspases via Degradation of IAPs , 2006, Cell.
[27] R. Ueda,et al. IKKɛ Regulates F Actin Assembly and Interacts with Drosophila IAP1 in Cellular Morphogenesis , 2006, Current Biology.
[28] B. Lemaître,et al. The Drosophila Inhibitor of Apoptosis Protein DIAP2 Functions in Innate Immunity and Is Essential To Resist Gram-Negative Bacterial Infection , 2006, Molecular and Cellular Biology.
[29] G. Salvesen,et al. Human inhibitor of apoptosis proteins: why XIAP is the black sheep of the family , 2006, EMBO reports.
[30] Junying Yuan,et al. Divergence from a dedicated cellular suicide mechanism: exploring the evolution of cell death. , 2006, Molecular cell.
[31] M. Wigler,et al. Identification and Validation of Oncogenes in Liver Cancer Using an Integrative Oncogenomic Approach , 2006, Cell.
[32] G. Jayson,et al. Method validation and preliminary qualification of pharmacodynamic biomarkers employed to evaluate the clinical efficacy of an antisense compound (AEG35156) targeted to the X-linked inhibitor of apoptosis protein XIAP , 2006, British Journal of Cancer.
[33] J. C. Wilkinson,et al. XIAP Is a copper binding protein deregulated in Wilson's disease and other copper toxicosis disorders. , 2006, Molecular cell.
[34] G. Salvesen,et al. The Human Anti-apoptotic Proteins cIAP1 and cIAP2 Bind but Do Not Inhibit Caspases* , 2006, Journal of Biological Chemistry.
[35] W. Dietrich,et al. The Birc1e cytosolic pattern-recognition receptor contributes to the detection and control of Legionella pneumophila infection , 2006, Nature Immunology.
[36] John Calvin Reed,et al. Distinct BIR Domains of cIAP1 Mediate Binding to and Ubiquitination of Tumor Necrosis Factor Receptor-associated Factor 2 and Second Mitochondrial Activator of Caspases* , 2006, Journal of Biological Chemistry.
[37] R. Korneluk,et al. Inhibitor of Apoptosis Protein cIAP2 Is Essential for Lipopolysaccharide-Induced Macrophage Survival , 2006, Molecular and Cellular Biology.
[38] Holly McDonough,et al. Reduced Apaf-1 levels in cardiomyocytes engage strict regulation of apoptosis by endogenous XIAP , 2005, The Journal of cell biology.
[39] D. Vaux,et al. Determination of cell survival by RING-mediated regulation of inhibitor of apoptosis (IAP) protein abundance. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[40] H. Okano,et al. Drosophila caspase transduces Shaggy/GSK‐3β kinase activity in neural precursor development , 2005, The EMBO journal.
[41] S. Agrawal,et al. Application of XIAP Antisense to Cancer and Other Proliferative Disorders: Development of AEG35156/ GEM®640 , 2005, Annals of the New York Academy of Sciences.
[42] Heidi P. K. Enwald,et al. Inhibitor of apoptosis 2 and TAK1‐binding protein are components of the Drosophila Imd pathway , 2005, The EMBO journal.
[43] C. Duckett,et al. Reawakening the cellular death program in neoplasia through the therapeutic blockade of IAP function. , 2005, The Journal of clinical investigation.
[44] Michael Boutros,et al. An RNA interference screen ide.jpgies Inhibitor of Apoptosis Protein 2 as a regulator of innate immune signalling in Drosophila , 2005, EMBO reports.
[45] J. Ashwell,et al. TNF‐α induced c‐IAP1/TRAF2 complex translocation to a Ubc6‐containing compartment and TRAF2 ubiquitination , 2005, The EMBO journal.
[46] Honglin Zhou,et al. Constitutive NF-kappaB activation by the t(11;18)(q21;q21) product in MALT lymphoma is linked to deregulated ubiquitin ligase activity. , 2005, Cancer cell.
[47] K. Kuchitsu,et al. Identification of a novel gene family, paralogs of inhibitor of apoptosis proteins present in plants, fungi, and animals , 2005, Apoptosis.
[48] D. Goeddel,et al. Posttranscriptional Downregulation of c-IAP2 by the Ubiquitin Protein Ligase c-IAP1 In Vivo , 2005, Molecular and Cellular Biology.
[49] David L. Vaux,et al. IAPs, RINGs and ubiquitylation , 2005, Nature Reviews Molecular Cell Biology.
[50] S. Tangye,et al. Molecular and cellular pathogenesis of X‐linked lymphoproliferative disease , 2005, Immunological reviews.
[51] W. Skarnes,et al. The Birc6 (Bruce) gene regulates p53 and the mitochondrial pathway of apoptosis and is essential for mouse embryonic development. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[52] John Calvin Reed,et al. cIAP1 Localizes to the nuclear compartment and modulates the cell cycle. , 2005, Cancer research.
[53] J. Kelly,et al. Neuronal Apoptosis-inhibitory Protein Does Not Interact with Smac and Requires ATP to Bind Caspase-9* , 2004, Journal of Biological Chemistry.
[54] Yigong Shi,et al. Caspases, IAPs and Smac/DIABLO: mechanisms from structural biology. , 2004, Trends in biochemical sciences.
[55] John Calvin Reed,et al. An IAP-IAP Complex Inhibits Apoptosis* , 2004, Journal of Biological Chemistry.
[56] T. Noda,et al. Apollon ubiquitinates SMAC and caspase-9, and has an essential cytoprotection function , 2004, Nature Cell Biology.
[57] Yigong Shi. Caspase activation, inhibition, and reactivation: A mechanistic view , 2004, Protein science : a publication of the Protein Society.
[58] Asaf Rotem,et al. Mitochondrial pro-apoptotic ARTS protein is lost in the majority of acute lymphoblastic leukemia patients , 2004, Oncogene.
[59] D. Montell,et al. A Role for Drosophila IAP1-Mediated Caspase Inhibition in Rac-Dependent Cell Migration , 2004, Cell.
[60] C. Morrissey,et al. An antisense oligonucleotide to cIAP‐1 sensitizes prostate cancer cells to fas and TNFα mediated apoptosis , 2004, The Prostate.
[61] Chunying Du,et al. Smac/DIABLO Selectively Reduces the Levels of c-IAP1 and c-IAP2 but Not That of XIAP and Livin in HeLa Cells* , 2004, Journal of Biological Chemistry.
[62] Asaf Rotem,et al. The mitochondrial ARTS protein promotes apoptosis through targeting XIAP , 2004, The EMBO journal.
[63] C. Bakal,et al. Survivin Loss in Thymocytes Triggers p53-mediated Growth Arrest and p53-independent Cell Death , 2004, The Journal of experimental medicine.
[64] C. Wijmenga,et al. A novel role for XIAP in copper homeostasis through regulation of MURR1 , 2004, The EMBO journal.
[65] R. Rich,et al. Requirement of Both the Second and Third BIR Domains for the Relief of X-linked Inhibitor of Apoptosis Protein (XIAP)-mediated Caspase Inhibition by Smac* , 2003, Journal of Biological Chemistry.
[66] C. Thompson,et al. Critical function of endogenous XIAP in regulating caspase activation during sympathetic neuronal apoptosis , 2003, The Journal of cell biology.
[67] Yahong Lin,et al. A JNK-Dependent Pathway Is Required for TNFα-Induced Apoptosis , 2003, Cell.
[68] Y. Xiong,et al. A Role for NF-κB Essential Modifier/IκB Kinase-γ (NEMO/IKKγ) Ubiquitination in the Activation of the IκB Kinase Complex by Tumor Necrosis Factor-α* , 2003, Journal of Biological Chemistry.
[69] Y. Xiong,et al. A role for NEMO/IKKγ Ubiquitination in the activation of the IκB kinase complex by TNF-α , 2003 .
[70] G. Wilson,et al. Apoptosis Genes and Resistance to Cancer Therapy: What Does the Experimental and Clinical Data Tell Us? , 2003, Cancer biology & therapy.
[71] M. Endrizzi,et al. Naip5 Affects Host Susceptibility to the Intracellular Pathogen Legionella pneumophila , 2003, Current Biology.
[72] Michael R. Olson,et al. Drosophila Bruce Can Potently Suppress Rpr- and Grim-Dependent but Not Hid-Dependent Cell Death , 2002, Current Biology.
[73] Seamus J. Martin. Destabilizing Influences in Apoptosis Sowing the Seeds of IAP Destruction , 2002, Cell.
[74] Jun R Huh,et al. Hid, Rpr and Grim negatively regulate DIAP1 levels through distinct mechanisms , 2002, Nature Cell Biology.
[75] G. Gordon,et al. Inhibitor of apoptosis protein-1 promotes tumor cell survival in mesothelioma. , 2002, Carcinogenesis.
[76] Daniel A. Colón-Ramos,et al. Reaper eliminates IAP proteins through stimulated IAP degradation and generalized translational inhibition , 2002, Nature Cell Biology.
[77] D. MacEwan. TNF receptor subtype signalling: differences and cellular consequences. , 2002, Cellular signalling.
[78] Yili Yang,et al. TNF-RII and c-IAP1 mediate ubiquitination and degradation of TRAF2 , 2002, Nature.
[79] S. Srinivasula,et al. c-IAP1 blocks TNFalpha-mediated cytotoxicity upstream of caspase-dependent and -independent mitochondrial events in human leukemic cells. , 2001, Biochemical and biophysical research communications.
[80] D. Vaux,et al. Two kinds of BIR-containing protein - inhibitors of apoptosis, or required for mitosis. , 2001, Journal of cell science.
[81] Stephanie Birkey Reffey,et al. Characterization of XIAP-Deficient Mice , 2001, Molecular and Cellular Biology.
[82] R. Korneluk,et al. Thymocyte-targeted overexpression of xiap transgene disrupts T lymphoid apoptosis and maturation , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[83] Emad S. Alnemri,et al. A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis , 2001, Nature.
[84] K. Tamai,et al. Identification of XAF1 as an antagonist of XIAP anti-Caspase activity , 2001, Nature Cell Biology.
[85] S. Srinivasula,et al. Molecular Determinants of the Caspase-promoting Activity of Smac/DIABLO and Its Role in the Death Receptor Pathway* , 2000, The Journal of Biological Chemistry.
[86] D. Vaux,et al. Survivin and the inner centromere protein INCENP show similar cell-cycle localization and gene knockout phenotype , 2000, Current Biology.
[87] Stephen W. Fesik,et al. NMR Structure and Mutagenesis of the Third Bir Domain of the Inhibitor of Apoptosis Protein XIAP* , 2000, The Journal of Biological Chemistry.
[88] Tony Hunter,et al. Structural basis for phosphoserine-proline recognition by group IV WW domains , 2000, Nature Structural Biology.
[89] Christian Stehlik,et al. Activation of NF-κB by XIAP, the X Chromosome-linked Inhibitor of Apoptosis, in Endothelial Cells Involves TAK1* , 2000, The Journal of Biological Chemistry.
[90] J. Noel,et al. Structure of the human anti-apoptotic protein survivin reveals a dimeric arrangement , 2000, Nature Structural Biology.
[91] Yili Yang,et al. Ubiquitin protein ligase activity of IAPs and their degradation in proteasomes in response to apoptotic stimuli. , 2000, Science.
[92] M. Lenardo,et al. A crucial role for p80 TNF‐R2 in amplifying p60 TNF‐R1 apoptosis signals in T lymphocytes , 2000, European journal of immunology.
[93] Stephen W. Fesik,et al. NMR structure and mutagenesis of the inhibitor-of-apoptosis protein XIAP , 1999, Nature.
[94] S. Fang,et al. RING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitination. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[95] D. Vaux,et al. Solution structure of a baculoviral inhibitor of apoptosis (IAP) repeat , 1999, Nature Structural Biology.
[96] Naoto Ueno,et al. XIAP, a cellular member of the inhibitor of apoptosis protein family, links the receptors to TAB1–TAK1 in the BMP signaling pathway , 1999, The EMBO journal.
[97] C. Y. Wang,et al. NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation. , 1998, Science.
[98] J C Reed,et al. A Single BIR Domain of XIAP Sufficient for Inhibiting Caspases* , 1998, The Journal of Biological Chemistry.
[99] C. Thompson,et al. CD30-dependent degradation of TRAF2: implications for negative regulation of TRAF signaling and the control of cell survival. , 1997, Genes & development.
[100] M. Malim,et al. Suppression of tumor necrosis factor-induced cell death by inhibitor of apoptosis c-IAP2 is under NF-kappaB control. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[101] D. Goeddel,et al. The tumor necrosis factor receptor 2 signal transducers TRAF2 and c-IAP1 are components of the tumor necrosis factor receptor 1 signaling complex. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[102] Mike Rothe,et al. The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins , 1995, Cell.
[103] D. Goeddel,et al. Decreased sensitivity to tumour-necrosis factor but normal T-cell development in TNF receptor-2-deficient mice , 1994, Nature.
[104] M. Birnbaum,et al. An apoptosis-inhibiting gene from a nuclear polyhedrosis virus encoding a polypeptide with Cys/His sequence motifs , 1994, Journal of virology.
[105] R. Zinkernagel,et al. Mice lacking the tumour necrosis factor receptor 1 are resistant to IMF-mediated toxicity but highly susceptible to infection by Listeria monocytogenes , 1993, Nature.
[106] R. J. Clem,et al. An apoptosis-inhibiting baculovirus gene with a zinc finger-like motif , 1993, Journal of virology.
[107] R. J. Clem,et al. Prevention of apoptosis by a baculovirus gene during infection of insect cells. , 1991, Science.
[108] Vishva M Dixit,et al. IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis. , 2007, Cell.
[109] Seda Çöl Arslan,et al. Malt1 ubiquitination triggers NF-kappaB signaling upon T-cell activation. , 2007, The EMBO journal.
[110] Vinay Tergaonkar,et al. IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis. , 2007, Cell.
[111] R. Ueda,et al. IKK epsilon regulates F actin assembly and interacts with Drosophila IAP1 in cellular morphogenesis. , 2006, Current biology : CB.
[112] D. Vaux,et al. XIAP-deficiency leads to delayed lobuloalveolar development in the mammary gland , 2005, Cell Death and Differentiation.
[113] D. Altieri. Validating survivin as a cancer therapeutic target , 2003, Nature Reviews Cancer.
[114] Y. Xiong,et al. A role for NF-kappaB essential modifier/IkappaB kinase-gamma (NEMO/IKKgamma) ubiquitination in the activation of the IkappaB kinase complex by tumor necrosis factor-alpha. , 2003, The Journal of biological chemistry.
[115] Yahong Lin,et al. A JNK-dependent pathway is required for TNFalpha-induced apoptosis. , 2003, Cell.
[116] Smac agonists sensitize for Apo 2 L / TRAILor anticancer drug-induced apoptosis and induce regression of malignant glioma in vivo , 2002, Nature Reviews Cancer.
[117] Michael Weller,et al. Smac agonists sensitize for Apo2L/TRAIL- or anticancer drug-induced apoptosis and induce regression of malignant glioma in vivo , 2002, Nature Medicine.
[118] Marty W. Mayo,et al. NF-k B Antiapoptosis : Induction of TRAF 1 and TRAF 2 and c-IAP 1 and c-IAP 2 to Suppress Caspase-8 Activation , 1998 .