Crystal structure of human CDK4 in complex with a D-type cyclin
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[1] J. McCubrey,et al. P21Cip1 induced by Raf is associated with increased Cdk4 activity in hematopoietic cells , 2001, Oncogene.
[2] M. Serrano,et al. A p16INK4a-insensitive CDK4 mutant targeted by cytolytic T lymphocytes in a human melanoma , 1995, Science.
[3] Louis Guillou,et al. MDM2 and CDK4 Immunostainings Are Useful Adjuncts in Diagnosing Well-Differentiated and Dedifferentiated Liposarcoma Subtypes: A Comparative Analysis of 559 Soft Tissue Neoplasms With Genetic Data , 2005, The American journal of surgical pathology.
[4] L. Johnson,et al. The structural basis for specificity of substrate and recruitment peptides for cyclin-dependent kinases , 1999, Nature Cell Biology.
[5] C. Sherr,et al. Regulation of cyclin D-dependent kinase 4 (cdk4) by cdk4-activating kinase , 1994, Molecular and cellular biology.
[6] K D Watenpaugh,et al. The Cyclin-dependent Kinases cdk2 and cdk5 Act by a Random, Anticooperative Kinetic Mechanism* , 2001, The Journal of Biological Chemistry.
[7] M. Noble,et al. Reversal of Growth Suppression by p107 via Direct Phosphorylation by Cyclin D1/Cyclin-Dependent Kinase 4 , 2002, Molecular and Cellular Biology.
[8] M. E. M. Noble,et al. The structure of CDK4/cyclin D3 has implications for models of CDK activation , 2009, Proceedings of the National Academy of Sciences.
[9] Manuel Serrano,et al. Crystal structure of the complex of the cyclin D-dependent kinase Cdk6 bound to the cell-cycle inhibitor p19INK4d , 1998, Nature.
[10] Collaborative Computational,et al. The CCP4 suite: programs for protein crystallography. , 1994, Acta crystallographica. Section D, Biological crystallography.
[11] S. Cox,et al. A cyclin D1/cyclin-dependent kinase 4 binding site within the C domain of the retinoblastoma protein. , 2001, Cancer research.
[12] N. Pavletich,et al. Structural basis of inhibition of CDK-cyclin complexes by INK4 inhibitors. , 2000, Genes & development.
[13] John A. Tainer,et al. Kinetic Mechanism of Activation of the Cdk2/Cyclin A Complex , 2002, The Journal of Biological Chemistry.
[14] T. McDonnell,et al. Characterization of 4 mantle cell lymphoma cell lines. , 2003, Archives of pathology & laboratory medicine.
[15] G J Kleywegt,et al. Template convolution to enhance or detect structural features in macromolecular electron-density maps. , 1997, Acta crystallographica. Section D, Biological crystallography.
[16] Randy J Read,et al. Electronic Reprint Biological Crystallography Likelihood-enhanced Fast Translation Functions Biological Crystallography Likelihood-enhanced Fast Translation Functions , 2022 .
[17] R. Hoess,et al. Defining the substrate specificity of cdk4 kinase-cyclin D1 complex. , 1999, Carcinogenesis.
[18] Tiansen Li,et al. Cyclin D1-dependent kinase activity in murine development and mammary tumorigenesis. , 2006, Cancer cell.
[19] Y. De Launoit,et al. Regulated Activating Thr172 Phosphorylation of Cyclin-Dependent Kinase 4(CDK4): Its Relationship with Cyclins and CDK “Inhibitors” , 2006, Molecular and Cellular Biology.
[20] Raju Tomer,et al. Different mechanisms of cyclin D1 overexpression in multiple myeloma revealed by fluorescence in situ hybridization and quantitative analysis of mRNA levels. , 2004, Blood.
[21] L. Johnson,et al. The crystal structure of human CDK7 and its protein recognition properties. , 2004, Structure.
[22] M. Barbacid,et al. Cyclin D-dependent kinases, INK4 inhibitors and cancer. , 2002, Biochimica et biophysica acta.
[23] L. Johnson,et al. The structure of cyclin E1/CDK2: implications for CDK2 activation and CDK2‐independent roles , 2005, The EMBO journal.
[24] A. Papanikolaou,et al. Cyclin D1 in breast cancer pathogenesis. , 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[25] G. Murshudov,et al. Refinement of macromolecular structures by the maximum-likelihood method. , 1997, Acta crystallographica. Section D, Biological crystallography.
[26] M. Barbacid,et al. To cycle or not to cycle: a critical decision in cancer , 2001, Nature reviews. Cancer.
[27] Kornelia Polyak,et al. Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex , 1995, Nature.
[28] Rajesh P. N. Rao,et al. Purification, Characterization, and Kinetic Mechanism of Cyclin D1·CDK4, a Major Target for Cell Cycle Regulation* , 1998, The Journal of Biological Chemistry.
[29] L. Johnson,et al. The structure of P‐TEFb (CDK9/cyclin T1), its complex with flavopiridol and regulation by phosphorylation , 2008, The EMBO journal.
[30] C. Auffray,et al. The I.M.A.G.E. Consortium: an integrated molecular analysis of genomes and their expression. , 1996, Genomics.
[31] K. Coulonval,et al. Regulation of CDK4 , 2006, Cell Division.
[32] R. Hoess,et al. Defining the minimal portion of the retinoblastoma protein that serves as an efficient substrate for cdk4 kinase/cyclin D1 complex. , 1998, Carcinogenesis.
[33] E. Lees,et al. Cyclin D-CDK Subunit Arrangement Is Dependent on the Availability of Competing INK4 and p21 Class Inhibitors , 1999, Molecular and Cellular Biology.
[34] J. Massagué,et al. Differential Interaction of the Cyclin-dependent Kinase (Cdk) Inhibitor p27Kip1 with Cyclin A-Cdk2 and Cyclin D2-Cdk4* , 1997, The Journal of Biological Chemistry.
[35] K. G. Coleman,et al. Identification of CDK4 Sequences Involved in Cyclin D1 and p16 Binding* , 1997, The Journal of Biological Chemistry.
[36] G. Bricogne,et al. Refinement of severely incomplete structures with maximum likelihood in BUSTER-TNT. , 2004, Acta crystallographica. Section D, Biological crystallography.
[37] F. McCormick,et al. The RB and p53 pathways in cancer. , 2002, Cancer cell.
[38] N. Pattabiraman,et al. Selectivity and potency of cyclin-dependent kinase inhibitors , 2006, The AAPS Journal.
[39] Sung-Hou Kim,et al. Structural basis for CDK6 activation by a virus-encoded cyclin , 2002, Nature Structural Biology.
[40] Sung-Hou Kim,et al. Crystal structure of cyclin-dependent kinase 2 , 1993, Nature.
[41] M. Serrano,et al. Activation of cyclin D1-kinase in murine fibroblasts lacking both p21Cip1 and p27Kip1 , 2002, Oncogene.
[42] J. Herman,et al. Identification of mutations that disrupt phosphorylation-dependent nuclear export of cyclin D1 , 2006, Oncogene.
[43] R. Weinberg,et al. Function of a human cyclin gene as an oncogene. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[44] P. Jeffrey,et al. Structural basis of cyclin-dependent kinase activation by phosphorylation , 1996, Nature Structural Biology.
[45] James M. Roberts,et al. The p21Cip1 and p27Kip1 CDK ‘inhibitors’ are essential activators of cyclin D‐dependent kinases in murine fibroblasts , 1999, The EMBO journal.
[46] P. Kaldis. The N-terminal Peptide of the Kaposi's Sarcoma-associated Herpesvirus (KSHV)-cyclin Determines Substrate Specificity* , 2005, Journal of Biological Chemistry.
[47] K. Ball,et al. Docking-Dependent Regulation of the Rb Tumor Suppressor Protein by Cdk4 , 2004, Molecular and Cellular Biology.
[48] F. Neipel,et al. Kaposi's sarcoma-associated herpesvirus encodes a functional cyclin , 1997, Journal of virology.
[49] K. Arndt,et al. Identification of a Conserved Sequence Motif That Promotes Cdc37 and Cyclin D1 Binding to Cdk4* , 2004, Journal of Biological Chemistry.
[50] J. LaBaer,et al. New functional activities for the p21 family of CDK inhibitors. , 1997, Genes & development.