Isolated Brain Cysts in Children Afflicted with Congenital Cytomegalovirus

In our clinic, isolated brain cysts identified via early ultrasound are considered as central nervous system involvement in infants with children with congenital cytomegalovirus (cCMV). All infants were diagnosed with caudothalamic or subependymal cysts. When treated according to the cCMV protocol, these patients have an excellent prognosis and no neurological sequelae. Further data on the significance of different cysts in relation to cCMV is warranted.

[1]  E. Bilavsky,et al.  Epidemiology of cytomegalovirus infection in pregnancy in Israel: Real‐world data from a large healthcare organization , 2021, Journal of medical virology.

[2]  S. Laroche,et al.  Cranial ultrasound and MRI: complementary or not in the diagnostic assessment of children with congenital CMV infection? , 2021, European Journal of Pediatrics.

[3]  A. Monteagudo,et al.  Intracranial Cysts. , 2020, American journal of obstetrics and gynecology.

[4]  National Institute of Allergy and Infectious Disease , 2020, Definitions.

[5]  P. Soler-Palacín,et al.  Role of Magnetic Resonance Imaging and Cranial Ultrasonography in Congenital Cytomegalovirus Infection. , 2019, The Pediatric infectious disease journal.

[6]  D. Bruzzese,et al.  Neuroimaging Profiles and Neurodevelopmental Outcome in Infants With Congenital Cytomegalovirus Infection , 2018, The Pediatric infectious disease journal.

[7]  Anonymous accepted for publication , 2018 .

[8]  N. Klein,et al.  Congenital Cytomegalovirus: A European Expert Consensus Statement on Diagnosis and Management , 2017, The Pediatric infectious disease journal.

[9]  Wendy J M van Zuylen,et al.  Congenital cytomegalovirus infection in pregnancy and the neonate: consensus recommendations for prevention, diagnosis, and therapy. , 2017, The Lancet. Infectious diseases.

[10]  J. Pardo,et al.  Hearing outcome of infants with congenital cytomegalovirus and hearing impairment , 2016, Archives of Disease in Childhood.

[11]  L. D. de Vries,et al.  Neuro-Imaging Findings in Infants with Congenital Cytomegalovirus Infection: Relation to Trimester of Infection , 2015, Neonatology.

[12]  R. DeBiasi,et al.  Valganciclovir for symptomatic congenital cytomegalovirus disease. , 2015, The New England journal of medicine.

[13]  I. Dhooge,et al.  Hearing Loss and Congenital CMV Infection: A Systematic Review , 2014, Pediatrics.

[14]  T. Lazzarotto,et al.  Role of cerebral ultrasound and magnetic resonance imaging in newborns with congenital cytomegalovirus infection , 2014, Brain and Development.

[15]  Kai-Ping Chang,et al.  Cranial ultrasonographic findings in healthy full‐term neonates: A retrospective review , 2012, Journal of the Chinese Medical Association : JCMA.

[16]  H. Rabe,et al.  Diagnostic value of subependymal pseudocysts and choroid plexus cysts on neonatal cerebral ultrasound: a meta-analysis , 2009, Archives of Disease in Childhood: Fetal and Neonatal Edition.

[17]  M. T. Ryan,et al.  Supplemental Digital Content , 2013 .

[18]  B. Lee Intracranial cysts. , 1979, Radiology.