A degradative to secretory autophagy switch mediates mitochondria clearance in the absence of the mATG8-conjugation machinery
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H. Shao | R. Taneja | W. Ding | Auginia Natalia | Liming Wang | Yik-Lam Cho | Guang Lu | Hayden Weng Siong Tan | Shuo-Chien Ling | D. Kappei | Charlene Chan | Shih-Yin Tsai | Han-Ming Shen | Han Dong | Dennis Kappei | Huilin Shao
[1] J. Norman,et al. PINK1 drives production of mtDNA-containing extracellular vesicles to promote invasiveness , 2021, The Journal of cell biology.
[2] V. Pascual,et al. Erythroid mitochondrial retention triggers myeloid-dependent type I interferon in human SLE , 2021, Cell.
[3] B. Kuster,et al. Stress-primed secretory autophagy promotes extracellular BDNF maturation by enhancing MMP9 secretion , 2021, Nature Communications.
[4] F. Perez,et al. Specificities of exosome versus small ectosome secretion revealed by live intracellular tracking of CD63 and CD9 , 2021, Nature Communications.
[5] M. Zeviani,et al. Neural stem cells traffic functional mitochondria via extracellular vesicles , 2021, PLoS biology.
[6] Yohan Kim,et al. Mitovesicles are a novel population of extracellular vesicles of mitochondrial origin altered in Down syndrome , 2021, Science Advances.
[7] R. Cerione,et al. Isolation and characterization of extracellular vesicles produced by cell lines , 2021, STAR protocols.
[8] Mark R. Marten,et al. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 , 2021, Autophagy.
[9] S. Koh,et al. Neuroinflammation in neurodegenerative disorders: the roles of microglia and astrocytes , 2020, Translational Neurodegeneration.
[10] M. Koike,et al. Alternative mitochondrial quality control mediated by extracellular release , 2020, Autophagy.
[11] S. Honda,et al. Wipi3 is essential for alternative autophagy and its loss causes neurodegeneration , 2020, Nature Communications.
[12] Min Goo Lee,et al. Secretory autophagy machinery and vesicular trafficking are involved in HMGB1 secretion , 2020, Autophagy.
[13] A. Ballabio,et al. LC3 lipidation is essential for TFEB activation during the lysosomal damage response to kidney injury , 2020, Nature Cell Biology.
[14] R. Swerdlow,et al. Detection of mitochondria-pertinent components in exosomes. , 2020, Mitochondrion.
[15] D. Philpott,et al. Mitophagy pathways in health and disease , 2020, The Journal of cell biology.
[16] S. Priori,et al. A Network of Macrophages Supports Mitochondrial Homeostasis in the Heart , 2020, Cell.
[17] Amber L. Simpson,et al. Extracellular Vesicle and Particle Biomarkers Define Multiple Human Cancers , 2020, Cell.
[18] S. Bratman,et al. Bioactive DNA from extracellular vesicles and particles , 2020, Cell Death & Disease.
[19] Keiji Tanaka,et al. Critical role of mitochondrial ubiquitination and the OPTN–ATG9A axis in mitophagy , 2020, The Journal of cell biology.
[20] Ying Li,et al. A Translocation Pathway for Vesicle-Mediated Unconventional Protein Secretion , 2020, Cell.
[21] G. Stevanin,et al. Impairment of Lysosome Function and Autophagy in Rare Neurodegenerative Diseases , 2020, Journal of molecular biology.
[22] Alejandro Lucia,et al. Chronic inflammation in the etiology of disease across the life span , 2019, Nature Medicine.
[23] V. Deretic,et al. Mammalian Atg8 proteins regulate lysosome and autolysosome biogenesis through SNAREs , 2019, The EMBO journal.
[24] James H. Stronge,et al. Selective Autophagy of Mitochondria on a Ubiquitin-Endoplasmic-Reticulum Platform , 2019, Developmental cell.
[25] L. Montermini,et al. Mapping Subpopulations of Cancer Cell-Derived Extracellular Vesicles and Particles by Nano-Flow Cytometry. , 2019, ACS nano.
[26] G. Dorn,et al. Fragmented mitochondria released from microglia trigger A1 astrocytic response and propagate inflammatory neurodegeneration , 2019, Nature Neuroscience.
[27] Grégory Lavieu,et al. Content release of extracellular vesicles in a cell‐free extract , 2019, FEBS letters.
[28] Lin Li,et al. A Bacterial Effector Reveals the V-ATPase-ATG16L1 Axis that Initiates Xenophagy , 2019, Cell.
[29] D. Green,et al. LC3-Associated Endocytosis Facilitates β-Amyloid Clearance and Mitigates Neurodegeneration in Murine Alzheimer’s Disease , 2019, Cell.
[30] M. Gale,et al. Interleukin-1β Induces mtDNA Release to Activate Innate Immune Signaling via cGAS-STING. , 2019, Molecular cell.
[31] G. Schiavo,et al. Spatiotemporal Control of ULK1 Activation by NDP52 and TBK1 during Selective Autophagy , 2019, Molecular cell.
[32] J. New,et al. Autophagy-dependent secretion: mechanism, factors secreted, and disease implications , 2019, Autophagy.
[33] L. Tang,et al. Effect of a Single Bout of Exercise on Autophagy Regulation in Skeletal Muscle of High-Fat High-Sucrose Diet-Fed Mice , 2019, Journal of obesity & metabolic syndrome.
[34] Jaehoon Chung,et al. Subtyping of circulating exosome-bound amyloid β reflects brain plaque deposition , 2019, Nature Communications.
[35] M. Z. Cader,et al. Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer’s disease , 2019, Nature Neuroscience.
[36] S. Ichinose,et al. An alternative mitophagy pathway mediated by Rab9 protects the heart against ischemia , 2019, The Journal of clinical investigation.
[37] M. Lazarou,et al. LC3/GABARAPs drive ubiquitin-independent recruitment of Optineurin and NDP52 to amplify mitophagy , 2019, Nature Communications.
[38] G. Kroemer,et al. Biological Functions of Autophagy Genes: A Disease Perspective , 2019, Cell.
[39] Martin Eisenacher,et al. The PRIDE database and related tools and resources in 2019: improving support for quantification data , 2018, Nucleic Acids Res..
[40] M. Fukuda,et al. Revisiting Rab7 Functions in Mammalian Autophagy: Rab7 Knockout Studies , 2018, Cells.
[41] H. Paulson,et al. PINK1-dependent mitophagy is driven by the UPS and can occur independently of LC3 conversion , 2018, Cell Death & Differentiation.
[42] H. Cai,et al. Parkin and PINK1 mitigate STING-induced inflammation , 2018, Nature.
[43] Xingdong Zhou,et al. Chloroquine inhibits autophagic flux by decreasing autophagosome-lysosome fusion , 2018, Autophagy.
[44] F. Sánchez‐Madrid,et al. Priming of dendritic cells by DNA-containing extracellular vesicles from activated T cells through antigen-driven contacts , 2018, Nature Communications.
[45] T. Dokland,et al. Exosomal transfer of mitochondria from airway myeloid-derived regulatory cells to T cells☆ , 2018, Redox biology.
[46] M. Vila,et al. Mitochondrial Quality Control in Neurodegenerative Diseases: Focus on Parkinson's Disease and Huntington's Disease , 2018, Front. Neurosci..
[47] S. Gygi,et al. Dynamics of PARKIN-Dependent Mitochondrial Ubiquitylation in Induced Neurons and Model Systems Revealed by Digital Snapshot Proteomics. , 2018, Molecular cell.
[48] Thomas M. Durcan,et al. Mfn2 ubiquitination by PINK1/parkin gates the p97-dependent release of ER from mitochondria to drive mitophagy , 2018, eLife.
[49] J. Bangsbo,et al. Exercise and exercise training‐induced increase in autophagy markers in human skeletal muscle , 2018, Physiological reports.
[50] M. Kyba,et al. ULK1 phosphorylates Ser30 of BECN1 in association with ATG14 to stimulate autophagy induction , 2018, Autophagy.
[51] J. Harper,et al. Building and decoding ubiquitin chains for mitophagy , 2018, Nature Reviews Molecular Cell Biology.
[52] J. Fessel,et al. Mitochondrial DNA depletion by ethidium bromide decreases neuronal mitochondrial creatine kinase: Implications for striatal energy metabolism , 2017, PloS one.
[53] L. Norton,et al. Packaging and transfer of mitochondrial DNA via exosomes regulate escape from dormancy in hormonal therapy-resistant breast cancer , 2017, Proceedings of the National Academy of Sciences.
[54] Taki Nishimura,et al. Autophagosome formation is initiated at phosphatidylinositol synthase‐enriched ER subdomains , 2017, The EMBO journal.
[55] Prashant Mishra,et al. Prohibitin 2 Is an Inner Mitochondrial Membrane Mitophagy Receptor , 2017, Cell.
[56] D. Hall,et al. C. elegans Neurons Jettison Protein Aggregates and Mitochondria Under Neurotoxic Stress , 2017, Nature.
[57] K. Lidke,et al. Dedicated SNAREs and specialized TRIM cargo receptors mediate secretory autophagy , 2017, The EMBO journal.
[58] Masato Koike,et al. The ATG conjugation systems are important for degradation of the inner autophagosomal membrane , 2016, Science.
[59] G. Ramm,et al. Atg8 family LC3/GABARAP proteins are crucial for autophagosome–lysosome fusion but not autophagosome formation during PINK1/Parkin mitophagy and starvation , 2016, The Journal of cell biology.
[60] M. Lazarou,et al. Deciphering the Molecular Signals of PINK1/Parkin Mitophagy. , 2016, Trends in cell biology.
[61] T. Oka,et al. Constitutive Activation of PINK1 Protein Leads to Proteasome-mediated and Non-apoptotic Cell Death Independently of Mitochondrial Autophagy* , 2016, The Journal of Biological Chemistry.
[62] Sebastian A. Wagner,et al. Phosphorylation of OPTN by TBK1 enhances its binding to Ub chains and promotes selective autophagy of damaged mitochondria , 2016, Proceedings of the National Academy of Sciences.
[63] D. Voytas,et al. The ULK1 complex mediates MTORC1 signaling to the autophagy initiation machinery via binding and phosphorylating ATG14 , 2016, Autophagy.
[64] C. Théry,et al. Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes , 2016, Proceedings of the National Academy of Sciences.
[65] K. Guan,et al. Atg5-independent autophagy regulates mitochondrial clearance and is essential for iPSC reprogramming , 2015, Nature Cell Biology.
[66] Simon C Watkins,et al. Mesenchymal stem cells use extracellular vesicles to outsource mitophagy and shuttle microRNAs , 2015, Nature Communications.
[67] J. Burman,et al. The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy , 2015, Nature.
[68] K. Hashimoto,et al. Extrusion of mitochondrial contents from lipopolysaccharide-stimulated cells: Involvement of autophagy , 2015, Autophagy.
[69] D. Green,et al. Molecular characterization of LC3-associated phagocytosis reveals distinct roles for Rubicon, NOX2 and autophagy proteins , 2015, Nature Cell Biology.
[70] J. Harper,et al. Loss of neuronal Miro1 disrupts mitophagy and induces hyperactivation of the integrated stress response , 2015, Proceedings of the National Academy of Sciences.
[71] R. Means,et al. Mitochondrial DNA Stress Primes the Antiviral Innate Immune Response , 2014, Nature.
[72] T. Taniguchi,et al. Apoptotic Caspases Prevent the Induction of Type I Interferons by Mitochondrial DNA , 2014, Cell.
[73] Seamus J. Martin,et al. Parkin sensitizes toward apoptosis induced by mitochondrial depolarization through promoting degradation of Mcl-1. , 2014, Cell reports.
[74] N. Mizushima,et al. Ultrastructural analysis of autophagosome organization using mammalian autophagy-deficient cells , 2014, Journal of Cell Science.
[75] S. Gygi,et al. Quantitative proteomics reveal a feedforward mechanism for mitochondrial PARKIN translocation and ubiquitin chain synthesis. , 2014, Molecular cell.
[76] Michael I. Wilson,et al. WIPI2 Links LC3 Conjugation with PI3P, Autophagosome Formation, and Pathogen Clearance by Recruiting Atg12–5-16L1 , 2014, Molecular cell.
[77] R. Candau,et al. Autophagy and protein turnover signaling in slow-twitch muscle during exercise. , 2014, Medicine and science in sports and exercise.
[78] S. Honda,et al. Ulk1-mediated Atg5-independent macroautophagy mediates elimination of mitochondria from embryonic reticulocytes , 2014, Nature Communications.
[79] T. Hirokawa,et al. Ubiquitin is phosphorylated by PINK1 to activate parkin , 2014, Nature.
[80] Hakho Lee,et al. Label-free detection and molecular profiling of exosomes with a nano-plasmonic sensor , 2014, Nature Biotechnology.
[81] X. Liang,et al. Suppression of autophagy by chloroquine sensitizes 5-fluorouracil-mediated cell death in gallbladder carcinoma cells , 2014, Cell & Bioscience.
[82] R. Roos,et al. The V471A Polymorphism in Autophagy-Related Gene ATG7 Modifies Age at Onset Specifically in Italian Huntington Disease Patients , 2013, PloS one.
[83] R. Hawley,et al. A novel and functional variant within the ATG5 gene promoter in sporadic Parkinson's disease , 2013, Neuroscience Letters.
[84] R. Zubarev. The challenge of the proteome dynamic range and its implications for in‐depth proteomics , 2013, Proteomics.
[85] R. Hawley,et al. Genetic analysis of the ATG7 gene promoter in sporadic Parkinson's disease , 2013, Neuroscience Letters.
[86] Xiao-Ming Yin,et al. Mitophagy: mechanisms, pathophysiological roles, and analysis , 2012, Biological chemistry.
[87] Young Sang Kim,et al. Autophagic response to a single bout of moderate exercise in murine skeletal muscle , 2012, Journal of Physiology and Biochemistry.
[88] Robert Clarke,et al. Guidelines for the use and interpretation of assays for monitoring autophagy , 2012 .
[89] N. Mizushima,et al. Structures containing Atg9A and the ULK1 complex independently target depolarized mitochondria at initial stages of Parkin-mediated mitophagy , 2012, Journal of Cell Science.
[90] Herman I. May,et al. Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis , 2012, Nature.
[91] V. Deretic,et al. Autophagy‐based unconventional secretory pathway for extracellular delivery of IL‐1β , 2011, The EMBO journal.
[92] N. Myeku,et al. Dynamics of the Degradation of Ubiquitinated Proteins by Proteasomes and Autophagy , 2011, The Journal of Biological Chemistry.
[93] N. Mizushima,et al. Parkin Mediates Proteasome-dependent Protein Degradation and Rupture of the Outer Mitochondrial Membrane*♦ , 2011, The Journal of Biological Chemistry.
[94] Sonja Hess,et al. Broad activation of the ubiquitin–proteasome system by Parkin is critical for mitophagy , 2011, Human molecular genetics.
[95] Xiao-Ming Yin,et al. Dissecting the dynamic turnover of GFP-LC3 in the autolysosome , 2011, Autophagy.
[96] L. Tong,et al. Age at onset in Huntington’s disease is modified by the autophagy pathway: implication of the V471A polymorphism in Atg7 , 2010, Human Genetics.
[97] R. Youle,et al. Parkin overexpression selects against a deleterious mtDNA mutation in heteroplasmic cybrid cells , 2010, Proceedings of the National Academy of Sciences.
[98] N. Hattori,et al. PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy , 2010, The Journal of cell biology.
[99] Atsushi Tanaka,et al. PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin , 2010, PLoS biology.
[100] K. Otsu,et al. Discovery of Atg5/Atg7-independent alternative macroautophagy , 2009, Nature.
[101] M. Mann,et al. MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification , 2008, Nature Biotechnology.
[102] Gareth Griffiths,et al. Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum , 2008, The Journal of cell biology.
[103] T. Noda,et al. The Atg16L complex specifies the site of LC3 lipidation for membrane biogenesis in autophagy. , 2008, Molecular biology of the cell.
[104] F. Inagaki,et al. Structure of Atg5·Atg16, a Complex Essential for Autophagy* , 2007, Journal of Biological Chemistry.
[105] Aled Clayton,et al. Isolation and Characterization of Exosomes from Cell Culture Supernatants and Biological Fluids , 2006, Current protocols in cell biology.
[106] Masaaki Komatsu,et al. Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice , 2005, The Journal of cell biology.
[107] T. Ueno,et al. HsAtg4B/HsApg4B/Autophagin-1 Cleaves the Carboxyl Termini of Three Human Atg8 Homologues and Delipidates Microtubule-associated Protein Light Chain 3- and GABAA Receptor-associated Protein-Phospholipid Conjugates* , 2004, Journal of Biological Chemistry.
[108] N. Mizushima,et al. Two ubiquitin-like conjugation systems essential for autophagy. , 2004, Seminars in cell & developmental biology.
[109] V. Lelyveld,et al. A Single Protease, Apg4B, Is Specific for the Autophagy-related Ubiquitin-like Proteins GATE-16, MAP1-LC3, GABARAP, and Apg8L* , 2003, Journal of Biological Chemistry.
[110] Takeshi Noda,et al. A ubiquitin-like system mediates protein lipidation , 2000, Nature.
[111] Takeshi Noda,et al. Formation Process of Autophagosome Is Traced with Apg8/Aut7p in Yeast , 1999, The Journal of cell biology.
[112] G. Chamberlain,et al. Induction , 2015, A Warning for Fair Women.
[113] C. Kahn,et al. A muscle-specific insulin receptor knockout exhibits features of the metabolic syndrome of NIDDM without altering glucose tolerance. , 1998, Molecular cell.
[114] Michael D. George,et al. A protein conjugation system essential for autophagy , 1998, Nature.
[115] Han-Ming Shen,et al. Post-translational Modifications of Key Machinery in the Control of Mitophagy. , 2019, Trends in biochemical sciences.
[116] Marisa Ponpuak,et al. Secretory autophagy. , 2015, Current opinion in cell biology.