TNF-α Induces Two Distinct Caspase-8 Activation Pathways
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Xiaodong Wang | Xiaodong Wang | Fenghe Du | Lai Wang | Lai Wang | Fenghe Du
[1] W. Yeh,et al. Ubiquitination of RIP1 Regulates an NF-κB-Independent Cell-Death Switch in TNF Signaling , 2007, Current Biology.
[2] J. Tschopp,et al. The PIDDosome, a Protein Complex Implicated in Activation of Caspase-2 in Response to Genotoxic Stress , 2004, Science.
[3] Xiaodong Wang,et al. Smac, a Mitochondrial Protein that Promotes Cytochrome c–Dependent Caspase Activation by Eliminating IAP Inhibition , 2000, Cell.
[4] M. Feldmann,et al. Lasker Clinical Medical Research Award. TNF defined as a therapeutic target for rheumatoid arthritis and other autoimmune diseases. , 2003, Nature medicine.
[5] Yahong Lin,et al. A JNK-Dependent Pathway Is Required for TNFα-Induced Apoptosis , 2003, Cell.
[6] M. Karin. Nuclear factor-κB in cancer development and progression , 2006, Nature.
[7] David L. Vaux,et al. IAP Antagonists Target cIAP1 to Induce TNFα-Dependent Apoptosis , 2007, Cell.
[8] Xiaodong Wang,et al. A Small Molecule Smac Mimic Potentiates TRAIL- and TNFα-Mediated Cell Death , 2004, Science.
[9] M. Karin,et al. The E3 Ubiquitin Ligase Itch Couples JNK Activation to TNFα-induced Cell Death by Inducing c-FLIPL Turnover , 2006, Cell.
[10] P. Leder,et al. RIP: A novel protein containing a death domain that interacts with Fas/APO-1 (CD95) in yeast and causes cell death , 1995, Cell.
[11] Yili Yang,et al. Ubiquitin protein ligase activity of IAPs and their degradation in proteasomes in response to apoptotic stimuli. , 2000, Science.
[12] S. Srinivasula,et al. Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NF-κB activation , 2006, Nature Cell Biology.
[13] Peter Scheurich,et al. NF-κB Inducers Upregulate cFLIP, a Cycloheximide-Sensitive Inhibitor of Death Receptor Signaling , 2001, Molecular and Cellular Biology.
[14] P. Leder,et al. The death domain kinase RIP mediates the TNF-induced NF-kappaB signal. , 1998, Immunity.
[15] Margot Thome,et al. Inhibition of death receptor signals by cellular FLIP , 1997, Nature.
[16] M. Karin. Nuclear factor-kappaB in cancer development and progression. , 2006, Nature.
[17] D. Goeddel,et al. TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex. , 1996, Immunity.
[18] Stephen F. Betz,et al. Structural basis for binding of Smac/DIABLO to the XIAP BIR3 domain , 2000, Nature.
[19] J. Tschopp,et al. NF-κB Signals Induce the Expression of c-FLIP , 2001, Molecular and Cellular Biology.
[20] Gabriel Pineda,et al. Activation of IKK by TNFalpha requires site-specific ubiquitination of RIP1 and polyubiquitin binding by NEMO. , 2006, Molecular cell.
[21] Geng Wu,et al. Structural basis of IAP recognition by Smac/DIABLO , 2000, Nature.
[22] D. Goeddel,et al. Posttranscriptional Downregulation of c-IAP2 by the Ubiquitin Protein Ligase c-IAP1 In Vivo , 2005, Molecular and Cellular Biology.
[23] F. Martinon,et al. The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta. , 2002, Molecular cell.
[24] B. Seed,et al. RIP mediates tumor necrosis factor receptor 1 activation of NF‐kappaB but not Fas/APO‐1‐initiated apoptosis. , 1996, The EMBO journal.
[25] A. Ashkenazi,et al. Tumor Necrosis Factor An Apoptosis JuNKie? , 2004, Cell.
[26] Xiaodong Wang,et al. A small molecule Smac mimic potentiates TRAIL- and TNFalpha-mediated cell death. , 2004, Science.
[27] M. Malim,et al. Suppression of tumor necrosis factor-induced cell death by inhibitor of apoptosis c-IAP2 is under NF-kappaB control. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[28] C. Y. Wang,et al. NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation. , 1998, Science.
[29] Xiaodong Wang,et al. Structural and biochemical basis of apoptotic activation by Smac/DIABLO , 2000, Nature.
[30] J. Tschopp,et al. Induction of TNF Receptor I-Mediated Apoptosis via Two Sequential Signaling Complexes , 2003, Cell.
[31] J. Mier,et al. Phosphatidylinositol 3-Kinase/Akt Activity Regulates c-FLIP Expression in Tumor Cells* , 2001, The Journal of Biological Chemistry.
[32] Vishva M Dixit,et al. IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis. , 2007, Cell.
[33] Vinay Tergaonkar,et al. IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis. , 2007, Cell.
[34] Robert L Moritz,et al. Identification of DIABLO, a Mammalian Protein that Promotes Apoptosis by Binding to and Antagonizing IAP Proteins , 2000, Cell.
[35] Shao-Cong Sun,et al. Regulation of early wave of germ cell apoptosis and spermatogenesis by deubiquitinating enzyme CYLD. , 2007, Developmental cell.
[36] Y. You,et al. Ubiquitination of RIP Is Required for Tumor Necrosis Factor α-induced NF-κB Activation* , 2006, Journal of Biological Chemistry.
[37] Y. You,et al. Ubiquitination of RIP is required for tumor necrosis factor alpha-induced NF-kappaB activation. , 2006, The Journal of biological chemistry.
[38] J. Tschopp,et al. Life and death decisions: secondary complexes and lipid rafts in TNF receptor family signal transduction. , 2004, Immunity.
[39] S. Srinivasula,et al. Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NF-kappaB activation [corrected]. , 2006, Nature cell biology.
[40] D. Goeddel,et al. TNF-R1 Signaling: A Beautiful Pathway , 2002, Science.
[41] Wafik S El-Deiry,et al. Distinct Signaling Pathways in TRAIL- versus Tumor Necrosis Factor-Induced Apoptosis , 2006, Molecular and Cellular Biology.
[42] X. Liu,et al. An APAF-1·Cytochrome c Multimeric Complex Is a Functional Apoptosome That Activates Procaspase-9* , 1999, The Journal of Biological Chemistry.
[43] Brian Seed,et al. Fas triggers an alternative, caspase-8–independent cell death pathway using the kinase RIP as effector molecule , 2000, Nature Immunology.
[44] Stefan Grimm,et al. The Death Domain Kinase RIP Mediates the TNF-Induced NF-κB Signal , 1998 .
[45] J. Minna,et al. Autocrine TNFalpha signaling renders human cancer cells susceptible to Smac-mimetic-induced apoptosis. , 2007, Cancer cell.
[46] Yahong Lin,et al. A JNK-dependent pathway is required for TNFalpha-induced apoptosis. , 2003, Cell.
[47] A. Ashworth,et al. Identification of the familial cylindromatosis tumour-suppressor gene , 2000, Nature Genetics.
[48] M. Lenardo,et al. Competitive Control of Independent Programs of Tumor Necrosis Factor Receptor-Induced Cell Death by TRADD and RIP1 , 2006, Molecular and Cellular Biology.
[49] Chunying Du,et al. Smac/DIABLO Selectively Reduces the Levels of c-IAP1 and c-IAP2 but Not That of XIAP and Livin in HeLa Cells* , 2004, Journal of Biological Chemistry.