Polysaccharides from Phellinus linteus: A systematic review of their extractions, purifications, structures and functions.

[1]  Jianbo Xiao,et al.  Exploration of natural flavones’ bioactivity and bioavailability in chronic inflammation induced-type-2 diabetes mellitus , 2022, Critical reviews in food science and nutrition.

[2]  Sen Li,et al.  Polyphenolic Extracts of Coffee Cherry Husks Alleviated Colitis-Induced Neural Inflammation via NF-κB Signaling Regulation and Gut Microbiota Modification. , 2022, Journal of agricultural and food chemistry.

[3]  Zhenxia Du,et al.  Molecular imprinting of glycoproteins: From preparation to cancer theranostics , 2022, Theranostics.

[4]  M. Marschall,et al.  Synthesis, molecular features and biological activities of modified plant polysaccharides. , 2022, Carbohydrate polymers.

[5]  Jingkun Yan,et al.  Modulatory effects of polysaccharides from plants, marine algae and edible mushrooms on gut microbiota and related health benefits: A review. , 2022, International journal of biological macromolecules.

[6]  Z. Tan,et al.  Systematic evaluation of the anti-tumor effect of Phellinus linteus polysaccharide in thyroid carcinoma in vitro , 2022, Molecular Biology Reports.

[7]  J. Aweya,et al.  Bioactive polysaccharides from red seaweed as potent food supplements: a systematic review of their extraction, purification, and biological activities. , 2022, Carbohydrate polymers.

[8]  F. Luo,et al.  Targeting gut microbiota in type 2 diabetes mellitus: Potential roles of dietary flavonoids , 2021, Food Bioscience.

[9]  T. Yue,et al.  Edible fungal polysaccharides, the gut microbiota, and host health. , 2021, Carbohydrate polymers.

[10]  Huaying Du,et al.  VF-4 and DR-8 derived from salted egg white inhibit inflammatory activity via NF-κB/PI3K-Akt/MAPK signal transduction pathways in HT-29 cells induced by TNF-α. , 2021, Molecular nutrition & food research.

[11]  Zhidong Qiu,et al.  Inhibitory effects of Panax ginseng glycoproteins in models of doxorubicin-induced cardiac toxicity in vivo and in vitro. , 2021, Food & function.

[12]  Jun-ru Wang,et al.  Polysaccharides from Polyporus umbellatus: A review on their extraction, modification, structure, and bioactivities. , 2021, International journal of biological macromolecules.

[13]  D. Bendjeddou,et al.  Anti-inflammatory and antioxidant activity of the hot water-soluble polysaccharides from Anacyclus pyrethrum (L.) Lag. roots. , 2021, Journal of ethnopharmacology.

[14]  Yuliang Cheng,et al.  Echinacea purpurea polysaccharide prepared by fractional precipitation prevents alcoholic liver injury in mice by protecting the intestinal barrier and regulating liver-related pathways. , 2021, International journal of biological macromolecules.

[15]  Yan Wu,et al.  Purification of polysaccharides from Phellinus linteus by using an aqueous two-phase system and evaluation of the physicochemical and antioxidant properties of polysaccharides in vitro , 2021, Preparative biochemistry & biotechnology.

[16]  L. Bian,et al.  Untargeted lipidomics analysis of Mori Fructus polysaccharide on acute alcoholic liver injury in mice using ultra performance liquid chromatography-quadrupole-orbitrap-high resolution mass spectrometry. , 2021, International immunopharmacology.

[17]  Ke-Jian Liu,et al.  Recent advances in polysaccharides from Lentinus edodes (Berk.): Isolation, structures and bioactivities. , 2021, Food chemistry.

[18]  Gangliang Huang,et al.  Preparation, activity, and antioxidant mechanism of rice bran polysaccharide. , 2021, Food & function.

[19]  Xiaoqing Chen,et al.  Polysaccharides from natural resources exhibit great potential in the treatment of ulcerative colitis: A review. , 2020, Carbohydrate polymers.

[20]  M. Khotimchenko,et al.  Antitumor potential of carrageenans from marine red algae. , 2020, Carbohydrate polymers.

[21]  Junwen Cheng,et al.  Structural characterization and hypoglycemic activity of an intracellular polysaccharide from Sanghuangporus sanghuang mycelia. , 2020, International journal of biological macromolecules.

[22]  J. Ji,et al.  Modification of vitamin B6 on the associations of blood lead levels and cardiovascular diseases in the US adults , 2020, BMJ nutrition, prevention & health.

[23]  Jiayu Ma,et al.  Orthogonal Test Design for Optimization of the Extraction of Polysaccharides from Inonotus cuticularis and Their Antioxidant Activities , 2020, Chemistry & biodiversity.

[24]  Tingting Li,et al.  The Structural Characteristics and Biological Activities of Intracellular Polysaccharide Derived from Mutagenic Sanghuangporous sanghuang Strain , 2020, Molecules.

[25]  Dongfeng Wang,et al.  Effect of purity of tea polysaccharides on its antioxidant and hypoglycemic activities. , 2020, Journal of food biochemistry.

[26]  Dandan Qin,et al.  Enzymatic hydrolysis of polysaccharide from Auricularia auricula and characterization of the degradation product. , 2020, International journal of biological macromolecules.

[27]  D. Shang,et al.  Hepatoprotective effect of plant polysaccharides from natural resources: A review of the mechanisms and structure-activity relationship. , 2020, International journal of biological macromolecules.

[28]  E. Çapanoğlu,et al.  Polysaccharides from Marine Enteromorpha: Structure and function , 2020 .

[29]  Diego Morales,et al.  Isolation and comparison of α- and β-D-glucans from shiitake mushrooms (Lentinula edodes) with different biological activities. , 2020, Carbohydrate polymers.

[30]  Yunxiang Liang,et al.  Phellinus linteus polysaccharide extract improves insulin resistance by regulating gut microbiota composition , 2020, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[31]  Keishi Suga,et al.  Enzymatic hydrolysis of cellulose recovered from ionic liquid-salt aqueous two-phase system. , 2019, Journal of bioscience and bioengineering.

[32]  Xiaoying Zhang,et al.  Hepatoprotective effect of Phellinus linteus mycelia polysaccharide (PL-N1) against acetaminophen-induced liver injury in mouse. , 2019, International journal of biological macromolecules.

[33]  W. Cai,et al.  The Preparation and Structure Analysis Methods of Natural Polysaccharides of Plants and Fungi: A Review of Recent Development , 2019, Molecules.

[34]  Shu-Fang Chang,et al.  The Protective Effect of Hispidin against Hydrogen Peroxide-Induced Oxidative Stress in ARPE-19 Cells via Nrf2 Signaling Pathway , 2019, Biomolecules.

[35]  E. Peterson,et al.  A newly characterized exopolysaccharide from Sanghuangporus sanghuang , 2019, Journal of Microbiology.

[36]  Juqing Huang,et al.  Anti-inflammatory activity of polysaccharides from Phellinus linteus by regulating the NF-κB translocation in LPS-stimulated RAW264.7 macrophages. , 2019, International journal of biological macromolecules.

[37]  Yuhong Liu,et al.  A Review: The Bioactivities and Pharmacological Applications of Phellinus linteus , 2019, Molecules.

[38]  D. Lai,et al.  Ionic Liquid Aqueous Two-Phase Systems From a Pharmaceutical Perspective , 2019, Front. Chem..

[39]  Junwen Cheng,et al.  Silver nanoparticles in situ synthesized by polysaccharides from Sanghuangporus sanghuang and composites with chitosan to prepare scaffolds for the regeneration of infected full-thickness skin defects. , 2019, International journal of biological macromolecules.

[40]  Yunxiang Liang,et al.  Hypoglycemic and Hypolipidemic Effects of Phellinus Linteus Mycelial Extract from Solid-State Culture in A Rat Model of Type 2 Diabetes , 2019, Nutrients.

[41]  P. Tripathi,et al.  Gut microbiome and type 2 diabetes: where we are and where to go? , 2019, The Journal of nutritional biochemistry.

[42]  F. Luo,et al.  Polysaccharide isolated from Phellinus linteus mycelia exerts anti-inflammatory effects via MAPK and PPAR signaling pathways. , 2018, Carbohydrate polymers.

[43]  J. Wan,et al.  Polysaccharides extracted from Phellinus linteus ameliorate high-fat high-fructose diet induced insulin resistance in mice. , 2018, Carbohydrate polymers.

[44]  J. Chen,et al.  Methods of extraction, separation, purification, structural characterization for polysaccharides from aquatic animals and their major pharmacological activities , 2018, Critical reviews in food science and nutrition.

[45]  M. Eppink,et al.  Fractionation of proteins and carbohydrates from crude microalgae extracts using an ionic liquid based-aqueous two phase system , 2018, Separation and Purification Technology.

[46]  Pei-Wen Wang,et al.  Hepatoprotective Principles and Other Chemical Constituents from the Mycelium of Phellinus linteus , 2018, Molecules.

[47]  Baojun Xu,et al.  Anti-inflammatory effects of phytochemicals from fruits, vegetables, and food legumes: A review , 2018, Critical reviews in food science and nutrition.

[48]  E. Peterson,et al.  Structural characterization of two endopolysaccharides from Phellinus sp. and their immunologic effects by intragastric administration in a healthy mammalian model. , 2018, Food & function.

[49]  Xuesong Huang,et al.  Recent Advances in Marine Algae Polysaccharides: Isolation, Structure, and Activities , 2017, Marine drugs.

[50]  H. Miyaoka,et al.  Phellilane L, Sesquiterpene Metabolite of Phellinus linteus: Isolation, Structure Elucidation, and Asymmetric Total Synthesis. , 2017, The Journal of organic chemistry.

[51]  Guan-Jhong Huang,et al.  3, 4‐dihydroxybenzalacetone attenuates lipopolysaccharide‐induced inflammation in acute lung injury via down‐regulation of MMP‐2 and MMP‐9 activities through suppressing ROS‐mediated MAPK and PI3K/AKT signaling pathways , 2017, International immunopharmacology.

[52]  Jaehwi Lee,et al.  Marine polysaccharides: therapeutic efficacy and biomedical applications , 2017, Archives of pharmacal research.

[53]  F. Luo,et al.  Octacosanol Attenuates Inflammation in Both RAW264.7 Macrophages and a Mouse Model of Colitis. , 2017, Journal of agricultural and food chemistry.

[54]  S. Bystrický,et al.  Efficient separation of mannan-protein mixtures by ionic liquid aqueous two-phase system, comparison with lectin affinity purification. , 2017, International journal of biological macromolecules.

[55]  Guan-Jhong Huang,et al.  3,4-Dihydroxybenzalactone Suppresses Human Non-Small Cell Lung Carcinoma Cells Metastasis via Suppression of Epithelial to Mesenchymal Transition, ROS-Mediated PI3K/AKT/MAPK/MMP and NFκB Signaling Pathways , 2017, Molecules.

[56]  G. A. Petersson,et al.  γ-Ionylidene-type sesquiterpenoids possessing antimicrobial activity against Porphyromonas gingivalis from Phellinus linteus and their absolute structure determination , 2017, The Journal of Antibiotics.

[57]  Jingkun Yan,et al.  Structure and antioxidative property of a polysaccharide from an ammonium oxalate extract of Phellinus linteus. , 2016, International journal of biological macromolecules.

[58]  Ying-yong Zhao,et al.  Traditional uses, fermentation, phytochemistry and pharmacology of Phellinus linteus: A review. , 2016, Fitoterapia.

[59]  E. Peterson,et al.  Structural characterization and anti-aging activity of a novel extracellular polysaccharide from fungus Phellinus sp. in a mammalian system. , 2016, Food & function.

[60]  H. Kwon,et al.  Protective Effect of 4-(3,4-Dihydroxyphenyl)-3-Buten-2-One from Phellinus linteus on Naproxen-Induced Gastric Antral Ulcers in Rats. , 2016, Journal of microbiology and biotechnology.

[61]  Jingkun Yan,et al.  Ultrasonic effects on the degradation kinetics, preliminary characterization and antioxidant activities of polysaccharides from Phellinus linteus mycelia. , 2016, Ultrasonics sonochemistry.

[62]  Chung-Chi Wu,et al.  Comparing the functional components, SOD-like activities, antimutagenicity, and nutrient compositions of Phellinus igniarius and Phellinus linteus mushrooms , 2016, Journal of food and drug analysis.

[63]  H. Senturk,et al.  Effects of Black Hoof Medicinal Mushroom, Phellinus linteus (Agaricomycetes), Polysaccharide Extract in Streptozotocin-Induced Diabetic Rats. , 2016, International journal of medicinal mushrooms.

[64]  T. Toida,et al.  Structural characterization and immunomodulatory effects of polysaccharides from Phellinus linteus and Phellinus igniarius on the IL-6/IL-10 cytokine balance of the mouse macrophage cell lines (RAW 264.7). , 2015, Food & function.

[65]  Kyung-Sook Chung,et al.  Anti-inflammatory Activity of Saxifragin via Inhibition of NF-κB Involves Caspase-1 Activation. , 2015, Journal of natural products.

[66]  Nan Peng,et al.  A novel polysaccharide from mycelia of cultured Phellinus linteus displays antitumor activity through apoptosis. , 2015, Carbohydrate polymers.

[67]  N. Chandel,et al.  ROS-dependent signal transduction. , 2015, Current opinion in cell biology.

[68]  N. Sung,et al.  Gamma-irradiated resveratrol negatively regulates LPS-induced MAPK and NF-κB signaling through TLR4 in macrophages. , 2015, International immunopharmacology.

[69]  Jing Zhao,et al.  Formation of ether-functionalized ionic-liquid-based aqueous two-phase systems and their application in separation of protein and saccharides. , 2015, The journal of physical chemistry. B.

[70]  G. Seo,et al.  Chemical Constituents of the Culture Broth of Phellinus linteus and Their Antioxidant Activity , 2015, Mycobiology.

[71]  Jingkun Yan,et al.  Structural features and antitumor activity of a novel polysaccharide from alkaline extract of Phellinus linteus mycelia. , 2015, Carbohydrate polymers.

[72]  Laura M Koontz.  TCA precipitation. , 2014, Methods in enzymology.

[73]  V. Lushchak.  Free radicals, reactive oxygen species, oxidative stress and its classification. , 2014, Chemico-biological interactions.

[74]  Yu-Wei Chang,et al.  Pheophytin a Inhibits Inflammation via Suppression of LPS-Induced Nitric Oxide Synthase-2, Prostaglandin E2, and Interleukin-1β of Macrophages , 2014, International journal of molecular sciences.

[75]  Jingkun Yan,et al.  Effect of extraction media on preliminary characterizations and antioxidant activities of Phellinus linteus polysaccharides. , 2014, Carbohydrate polymers.

[76]  Wei Chen,et al.  Hispidin derived from Phellinus linteus affords protection against acrylamide-induced oxidative stress in Caco-2 cells. , 2014, Chemico-biological interactions.

[77]  E. Peterson,et al.  Enhancing exopolysaccharide antioxidant formation and yield from Phellinus species through medium optimization studies. , 2014, Carbohydrate polymers.

[78]  G. Seo,et al.  Neuraminidase Inhibitors from the Fermentation Broth of Phellinus linteus , 2014, Mycobiology.

[79]  H. Senturk,et al.  Effects of polysaccharide from fruiting bodies of Agaricus bisporus, Agaricus brasiliensis, and Phellinus linteus on alcoholic liver injury , 2014, International journal of food sciences and nutrition.

[80]  B. Liu,et al.  Isolation, purification, and structural features of a polysaccharide from Phellinus linteus and its hypoglycemic effect in alloxan-induced diabetic mice. , 2014, Journal of food science.

[81]  J. Chen,et al.  Design of functional guanidinium ionic liquid aqueous two-phase systems for the efficient purification of protein. , 2014, Analytica chimica acta.

[82]  Meng-yao Guo,et al.  Bergenin Plays an Anti-Inflammatory Role via the Modulation of MAPK and NF-κB Signaling Pathways in a Mouse Model of LPS-Induced Mastitis , 2014, Inflammation.

[83]  H. Verhoeven,et al.  Phellinus linteus polysaccharide extracts increase the mitochondrial membrane potential and cause apoptotic death of THP-1 monocytes , 2013, Chinese Medicine.

[84]  Z. Lv,et al.  Activation of P27kip1-cyclin D1/E-CDK2 pathway by polysaccharide from Phellinus linteus leads to S-phase arrest in HT-29 cells. , 2013, Chemico-biological interactions.

[85]  Z. Lv,et al.  Polysaccharide from Phellinus linteus induces S-phase arrest in HepG2 cells by decreasing calreticulin expression and activating the P27kip1-cyclin A/D1/E-CDK2 pathway. , 2013, Journal of ethnopharmacology.

[86]  C. Jung,et al.  Identification of an anticancer compound against HT-29 cells from Phellinus linteus grown on germinated brown rice. , 2013, Asian Pacific journal of tropical biomedicine.

[87]  Chunyan Yan,et al.  Structural characterization and in vitro antitumor activity of a novel polysaccharide from Taxus yunnanensis. , 2013, Carbohydrate polymers.

[88]  Lishuai Ma,et al.  Effect of different drying methods on physicochemical properties and antioxidant activities of polysaccharides extracted from mushroom Inonotus obliquus , 2013 .

[89]  S. Nie,et al.  Purification, physicochemical characterisation and anticancer activity of a polysaccharide from Cyclocarya paliurus leaves. , 2013, Food chemistry.

[90]  J. Wan,et al.  Protective effect of Phellinus linteus polysaccharide extracts against thioacetamide-induced liver fibrosis in rats: a proteomics analysis , 2012, Chinese Medicine.

[91]  Wuxia Zhang,et al.  Antioxidative Properties of Crude Polysaccharides from Inonotus obliquus , 2012, International journal of molecular sciences.

[92]  L. Griensven,et al.  Antioxidative and immunomodulating activities of polysaccharide extracts of the medicinal mushrooms Agaricus bisporus, Agaricus brasiliensis, Ganoderma lucidum and Phellinus linteus , 2011 .

[93]  Ge Li,et al.  Protein-bound polysaccharide from Phellinus linteus inhibits tumor growth, invasion, and angiogenesis and alters Wnt/β-catenin in SW480 human colon cancer cells , 2011, BMC Cancer.

[94]  Shi Chen,et al.  Anti-tumor effects of proteoglycan from Phellinus linteus by immunomodulating and inhibiting Reg IV/EGFR/Akt signaling pathway in colorectal carcinoma. , 2011, International journal of biological macromolecules.

[95]  S. Seok,et al.  Phellinstatin, a new inhibitor of enoyl-ACP reductase produced by the medicinal fungus Phellinus linteus. , 2011, Bioorganic & medicinal chemistry letters.

[96]  J. H. Lee,et al.  Hispidin produced from Phellinus linteus protects pancreatic β-cells from damage by hydrogen peroxide , 2010, Archives of pharmacal research.

[97]  J. Hong,et al.  Evaluation of antidiabetic activity of polysaccharide isolated from Phellinus linteus in non-obese diabetic mouse. , 2010, International immunopharmacology.

[98]  Y. Jeon,et al.  Evaluation of the antioxidant activity of the fruiting body of Phellinus linteus using the on-line HPLC-DPPH method , 2009 .

[99]  Hyuk-Gu Park,et al.  New method development for nanoparticle extraction of water-soluble beta-(1-->3)-D-glucan from edible mushrooms, Sparassis crispa and Phellinus linteus. , 2009, Journal of agricultural and food chemistry.

[100]  S. Lim,et al.  Protein glycation inhibitors from the fruiting body of Phellinus linteus. , 2008, Biological & pharmaceutical bulletin.

[101]  J. Baker,et al.  Composition and proposed structure of a water-soluble glycan from the Keumsa Sangwhang Mushroom (Phellinus linteus). , 2008, Fitoterapia.

[102]  Sung-Hoon Kim,et al.  A medicinal mushroom: Phellinus linteus. , 2008, Current medicinal chemistry.

[103]  S. Lim,et al.  Inhibitory constituents of aldose reductase in the fruiting body of Phellinus linteus , 2008, Biological & pharmaceutical bulletin.

[104]  M. Inoue,et al.  Phellifuropyranone A: a new furopyranone compound isolated from fruit bodies of wild Phellinus linteus. , 2008, Chemical & pharmaceutical bulletin.

[105]  S. Yoo,et al.  Structural and biological study of carboxymethylated Phellinus linteus polysaccharides. , 2007, Journal of agricultural and food chemistry.

[106]  C-Y Chen,et al.  Phellinus linteus activates different pathways to induce apoptosis in prostate cancer cells , 2007, British Journal of Cancer.

[107]  S. Cui,et al.  Antitumor polysaccharides from mushrooms: a review on their isolation process, structural characteristics and antitumor activity , 2007 .

[108]  B. Min,et al.  Two novel furan derivatives from Phellinus linteus with anti-complement activity. , 2006, Bioorganic & medicinal chemistry letters.

[109]  Yung-Hyun Choi,et al.  Partial Characterization and Immunostimulatory Effect of a Novel Polysaccharide–Protein Complex Extracted from Phellinus linteus , 2006, Bioscience, biotechnology, and biochemistry.

[110]  C. Lee,et al.  Acidic polysaccharide from Phellinus linteus inhibits melanoma cell metastasis by blocking cell adhesion and invasion. , 2006, International immunopharmacology.

[111]  Ge Li,et al.  Protein-bound polysaccharide from Phellinus linteus induces G2/M phase arrest and apoptosis in SW480 human colon cancer cells. , 2004, Cancer letters.

[112]  M. Haruna,et al.  Identification of novel substituted fused aromatic compounds, meshimakobnol A and B, from natural Phellinus linteus fruit body , 2004 .

[113]  J. Yun,et al.  Production of a hypoglycemic, extracellular polysaccharide from the submerged culture of the mushroom, Phellinus linteus , 2001, Biotechnology Letters.

[114]  Y. Shon,et al.  Inhibition of cytochrome P450 isozymes in rat liver microsomes by polysaccharides derived from Phellinus linteus , 2004, Biotechnology Letters.

[115]  Y. Oh,et al.  Acidic polysaccharides isolated from Phellinus linteus induce phenotypic and functional maturation of murine dendritic cells. , 2003, Biochemical and biophysical research communications.

[116]  Y. Oh,et al.  Alleviation of experimental septic shock in mice by acidic polysaccharide isolated from the medicinal mushroom Phellinus linteus. , 2003, Biological & pharmaceutical bulletin.

[117]  Y. Oh,et al.  Acidic polysaccharide isolated from Phellinus linteus induces nitric oxide-mediated tumoricidal activity of macrophages through protein tyrosine kinase and protein kinase C. , 2003, Biochemical and biophysical research communications.

[118]  Y. Oh,et al.  Proteoglycan isolated from Phellinus linteus activates murine B lymphocytes via protein kinase C and protein tyrosine kinase. , 2003, International immunopharmacology.

[119]  Gi-Young Kim,et al.  Purification and characterization of acidic proteo-heteroglycan from the fruiting body of Phellinus linteus (Berk. & M.A. Curtis) Teng. , 2003, Bioresource technology.

[120]  H. Jun,et al.  Cellular and Molecular Pathogenic Mechanisms of Insulin‐Dependent Diabetes Mellitus , 2001, Annals of the New York Academy of Sciences.

[121]  J. McCord,et al.  The evolution of free radicals and oxidative stress. , 2000, The American journal of medicine.

[122]  Y. Jeon,et al.  The inhibitory effect of polysaccharides isolated from Phellinus linteus on tumor growth and metastasis. , 1999, Immunopharmacology.

[123]  R. Steinman,et al.  Dendritic cells and the control of immunity , 1998, Nature.

[124]  S. B. Han,et al.  B-lymphocyte-stimulating polysaccharide from mushroom Phellinus linteus. , 1995, Chemical & pharmaceutical bulletin.

[125]  T. Ikekawa,et al.  Antitumor polysaccharides from some polyporaceae, Ganoderma applanatum (Pers.) Pat and Phellinus linteus (Berk. et Curt) Aoshima. , 1971, Chemical and pharmaceutical bulletin.