Mediators of Inflammation in Response to Air Pollution: A Focus on Ozone and Nitrogen Dioxide

De recentes etudes epidemiologiques ont demontre la relation entre la pollution de l'air et les maladies respiratoires. En effet, les patients exposes au dioxyde d'azote et a l'ozone et souffrant d'asthme ou de rhinites allergiques developpent une reaction inflammatoire impliquant les neutrophiles, les lymphocytes et les mastocytes

[1]  D. Costa,et al.  Ozone exposure alters tracheobronchial mucociliary function in humans. , 1987, Journal of applied physiology.

[2]  D M Eddy,et al.  Synthesis of environmental evidence: nitrogen dioxide epidemiology studies. , 1992, Journal of the Air & Waste Management Association.

[3]  P. Border.  BREATHING IN OUR CITIES. URBAN AIR POLLUTION AND RESPIRATORY HEALTH , 1994 .

[4]  R. Hamilton,et al.  Ozone-induced increases in substance P and 8-epi-prostaglandin F2 alpha in the airways of human subjects. , 1993, American journal of respiratory cell and molecular biology.

[5]  D V Bates,et al.  Asthma attack periodicity: a study of hospital emergency visits in Vancouver. , 1990, Environmental research.

[6]  W. C. Adams,et al.  Indomethacin pretreatment reduces ozone-induced pulmonary function decrements in human subjects. , 1987, The American review of respiratory disease.

[7]  R. Devlin,et al.  Nitrogen Dioxide Exposure of Human Airway Epithelial Cells In Vitro Increases Steady-state Concentrations of Inflammatory Mediator mRNAs , 1995 .

[8]  W. Henderson,et al.  Inflammatory effects of ozone in the upper airways of subjects with asthma. , 1994, American journal of respiratory and critical care medicine.

[9]  R. Alexander,et al.  Vascular cell adhesion molecule-1 (VCAM-1) gene transcription and expression are regulated through an antioxidant-sensitive mechanism in human vascular endothelial cells. , 1993, The Journal of clinical investigation.

[10]  N. Roberts,et al.  Nitrogen dioxide exposure in vivo and human alveolar macrophage inactivation of influenza virus in vitro. , 1989, Environmental research.

[11]  M. Baggiolini,et al.  Neutrophil-activating peptide-1/interleukin 8, a novel cytokine that activates neutrophils. , 1989, The Journal of clinical investigation.

[12]  A M Collier,et al.  Respiratory responses of vigorously exercising children to 0.12 ppm ozone exposure. , 1985, The American review of respiratory disease.

[13]  D. House,et al.  Ozone-induced inflammation in the lower airways of human subjects. , 1989, The American review of respiratory disease.

[14]  R. Naclerio,et al.  Effect of ozone inhalation on the response to nasal challenge with antigen of allergic subjects. , 1990, The American review of respiratory disease.

[15]  R A Etzel,et al.  Exacerbations of childhood asthma and ozone pollution in Atlanta. , 1994, Environmental research.

[16]  M. Mustafa,et al.  Biochemical basis of ozone toxicity. , 1990, Free radical biology & medicine.

[17]  W. Pryor,et al.  Free radical pathology: inactivation of human alpha-1-proteinase inhibitor by products from the reaction of nitrogen dioxide with hydrogen peroxide and the etiology of emphysema. , 1982, Biochemical and biophysical research communications.

[18]  J S Boleij,et al.  Respiratory health effects of the indoor environment in a population of Dutch children. , 1990, The American review of respiratory disease.

[19]  K. B. Gross,et al.  Indomethacin does not inhibit the ozone-induced increase in bronchial responsiveness in human subjects. , 1990, The American review of respiratory disease.

[20]  J. Samet,et al.  Nitrogen dioxide and respiratory illnesses in infants. , 1993, The American review of respiratory disease.

[21]  J. Solway,et al.  Sensory neuropeptides and airway function. , 1991, Journal of applied physiology.

[22]  P J Lioy,et al.  The effect of ozone associated with summertime photochemical smog on the frequency of asthma visits to hospital emergency departments. , 1992, Environmental research.

[23]  N L Lapp.  Is asthma an inflammatory disease? , 1992, The West Virginia medical journal.

[24]  M. Hazucha.  Relationship between ozone exposure and pulmonary function changes. , 1987, Journal of applied physiology.

[25]  H. Boushey,et al.  Threshold concentration of ozone causing an increase in bronchial reactivity in humans and adaptation with repeated exposures. , 1981, The American review of respiratory disease.

[26]  S. Holgate,et al.  Ozone, airways and allergic airways disease , 1995, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

[27]  J. Balmes,et al.  Ozone-induced airway inflammation in human subjects as determined by airway lavage and biopsy. , 1993, The American review of respiratory disease.

[28]  L. Fabbri,et al.  In vivo exposure to nitrogen dioxide (NO2) induces a decrease in calcitonin gene-related peptide (CGRP) and tachykinin immunoreactivity in guinea-pig peripheral airways. , 1996, The European respiratory journal.

[29]  R. Shephard,et al.  Pulmonary function changes in ozone-interaction of concentration and ventilation. , 1976, Journal of applied physiology.

[30]  L. Folinsbee,et al.  Persistence of Ozone-Induced Changes in Lung Function and Airway Responsiveness , 1989 .

[31]  G. Kemmler,et al.  Effects of air pollution on the respiratory tract of children. , 1993, Pediatric pulmonology.

[32]  W. Pryor,et al.  Inactivation of human alpha-1-proteinase inhibitor by gas-phase cigarette smoke. , 1984, Biochemical and biophysical research communications.

[33]  S. Holgate,et al.  The free radical basis of air pollution: focus on ozone. , 1995, Respiratory medicine.

[34]  M. Baggiolini,et al.  Mechanism of neutrophil activation by NAF, a novel monocyte‐derived peptide agonist , 1988, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[35]  A. Konings.  Mechanisms of ozone toxicity in cultured cells. I. Reduced clonogenic ability of polyunsaturated fatty acid-supplemented fibroblasts. Effect of vitamin E. , 1986, Journal of toxicology and environmental health.

[36]  H. Boushey,et al.  O3-induced change in bronchial reactivity to methacholine and airway inflammation in humans. , 1986, Journal of applied physiology.