Assessing Beliefs about 'Environmental Illness/Multiple Chemical Sensitivity'

Knowledge representation was used to characterize beliefs in patients with Environmental Illness/Multiple Chemical Sensitivity (EI/MCS). EI/MCS patients, allergy and asthma patients, doctors and controls made relatedness judgments on concepts relevant to EI/MCS. Associative networks showed that EI/MCS patients viewed these concepts differently from others. Multiple chemical exposure was central in EI/ MCS networks, with many links to every other concept, but was only peripherally connected in the other subject networks. Similarity comparisons to an EI/MCS prototype network discriminated EI/MCS patients from the other control populations, as did an index based on critical concept pairs. This approach shows promise for distinguishing patient groups using belief structure.

[1]  M. Gilbert.  A characterization of chemical kindling with the pesticide endosulfan. , 1992, Neurotoxicology and teratology.

[2]  Z. J. Lipowski.  Somatization: the concept and its clinical application. , 1988, The American journal of psychiatry.

[3]  L. Morrow,et al.  A distinct pattern of personality disturbance following exposure to mixtures of organic solvents. , 1989, Journal of occupational medicine. : official publication of the Industrial Medical Association.

[4]  H. Staudenmayer,et al.  Neuropsychophysiology during relaxation in generalized, universal 'allergic' reactivity to the environment: a comparison study. , 1990, Journal of psychosomatic research.

[5]  G. Klerman,et al.  Overview: hypochondriasis, bodily complaints, and somatic styles. , 1983, The American journal of psychiatry.

[6]  L. Kirmayer,et al.  Illness Cognition, Symptom Reporting and Somatization in Family Medicine , 1986 .

[7]  Roger W. Schvaneveldt,et al.  Pathfinder associative networks: studies in knowledge organization , 1990 .

[8]  M. Cullen.  The worker with multiple chemical sensitivities: an overview. , 1987, Occupational medicine.

[9]  P. Cleary,et al.  The amplification of somatic symptoms. , 1988, Psychosomatic medicine.

[10]  E. K..  THE MEDICAL CLINICS OF NORTH AMERICA , 1937 .

[11]  Nancy J. Cooke,et al.  Effects of Computer Programming Experience on Network Representations of Abstract Programming Concepts , 1988, Int. J. Man Mach. Stud..

[12]  F. Durso,et al.  Graph-Theoretic Confirmation of Restructuring During Insight , 1994 .

[13]  Timothy E. Goldsmith,et al.  A structural assessment of classroom learning , 1990 .

[14]  C. Brodsky.  'Allergic to everything': a medical subculture. , 1983, Psychosomatics.

[15]  Tyler S. Lorig,et al.  Human EEG and odor response , 1989, Progress in Neurobiology.

[16]  M. Gilbert.  Neurotoxicants and Limbic Kindling , 1992 .

[17]  H. Staudenmayer,et al.  PSYCHOLOGICAL FACTORS COMPLICATING THE DIAGNOSIS OF WORK-RELATED CHEMICAL ILLNESS , 1992, Immunology and Allergy Clinics of North America.

[18]  J. Cotterill,et al.  TOTAL ALLERGY SYNDROME , 1982, The Lancet.

[19]  H. Staudenmayer,et al.  Adult sequelae of childhood abuse presenting as environmental illness. , 1993, Annals of allergy.

[20]  W. R. Kennedy,et al.  Clinical Ecology: Council on Scientific Affairs, American Medical Association , 1992 .

[21]  L. Housner,et al.  A Pathfinder analysis of pedagogical knowledge structures: a follow-up investigation. , 1993, Research quarterly for exercise and sport.

[22]  R. Goldstein,et al.  Environmental illness. A controlled study of 26 subjects with '20th century disease'. , 1990, JAMA.

[23]  W. Pierson,et al.  Clinical ecology: Approved by the executive committee of the American academy of allergy and immunology , 1986 .

[24]  J. Lacroix.  Assessing Illness Schemata in Patient Populations , 1991 .

[25]  Francis T. Durso,et al.  Network Structures in Proximity Data , 1989 .

[26]  S. Siegel,et al.  Pavlovian conditioning of rat mucosal mast cells to secrete rat mast cell protease II. , 1989, Science.

[27]  D E Meyer,et al.  Meaning, memory structure, and mental processes. , 1976, Science.

[28]  G. Schwartz,et al.  An olfactory-limbic model of multiple chemical sensitivity syndrome: Possible relationships to kindling and affective spectrum disorders , 1992, Biological Psychiatry.

[29]  H. Staudenmayer,et al.  Neuropsychophysiologic Observations in Patients Presenting with Environmental Illness , 1992, Toxicology and industrial health.

[30]  H. Staudenmayer,et al.  Double-blind provocation chamber challenges in 20 patients presenting with "multiple chemical sensitivity". , 1993, Regulatory toxicology and pharmacology : RTP.

[31]  M. Ross Quillian,et al.  The teachable language comprehender: a simulation program and theory of language , 1969, CACM.

[32]  H. Staudenmayer,et al.  The practical approach to the evaluation of suspected environmental exposures: chemical intolerance. , 1985, Annals of allergy.

[33]  J. Pennebaker,et al.  The psychology of somatic symptoms. , 1991 .

[34]  Nancy J. Cooke,et al.  Predicting judgment time from measures of psychological proximity. , 1992 .

[35]  C. Brewin.  Cognitive change processes in psychotherapy. , 1989, Psychological review.

[36]  Richard B. Gammage,et al.  Indoor Air and Human Health , 1986, The Lancet.

[37]  A. Dickinson.  Animal Conditioning and Learning Theory , 1987 .

[38]  J. Balmes,et al.  Behavioral sensitization to irritants/odorants after acute overexposures. , 1988, Journal of occupational medicine. : official publication of the Industrial Medical Association.

[39]  J. Bienenstock,et al.  Learned sensitivity. , 1993, Annals of allergy.

[40]  S. Mchugh,et al.  Illness Behavior: A Multidisciplinary Model , 1987 .

[41]  Francis T. Durso,et al.  Recall and Measures of Memory Organization , 1986 .

[42]  H. Staudenmayer,et al.  Vocal cord dysfunction: the importance of psychologic factors and provocation challenge testing. , 1987, The Journal of allergy and clinical immunology.

[43]  H. Eysenck,et al.  Theoretical foundations of behavior therapy , 1987 .

[44]  James E. Cone,et al.  Chemical Exposures: Low Levels and High Stakes , 1991 .

[45]  L. Housner,et al.  Pedagogical knowledge structures in prospective teachers: relationships to performance in a teaching methodology course. , 1993, Research quarterly for exercise and sport.

[46]  I. Selikoff.  Environmental medicine. , 1971, Environmental research.

[47]  S. Rachman.  Contributions to medical psychology , 1980 .

[48]  A. Terr.  Clinical ecology in the workplace. , 1989, Journal of occupational medicine. : official publication of the Industrial Medical Association.

[49]  James P. Hughes,et al.  Proctor and Hughes' Chemical Hazards of the Workplace , 1991 .

[50]  W. Daniell,et al.  Immunologic, Psychological, and Neuropsychological Factors in Multiple Chemical Sensitivity: A Controlled Study , 1993, Annals of Internal Medicine.

[51]  A. Terr.  Environmental illness. A clinical review of 50 cases. , 1986, Archives of internal medicine.

[52]  L. Morrow,et al.  Cacosmia and neurobehavioral dysfunction associated with occupational exposure to mixtures of organic solvents. , 1988, The American journal of psychiatry.

[53]  W. Katon,et al.  Allergic to life: psychological factors in environmental illness. , 1990, The American journal of psychiatry.

[54]  G. Mendelson.  Measurement of conscious symptom exaggeration by questionnaire: a clinical study. , 1987, Journal of psychosomatic research.

[55]  A. Terr.  "Multiple chemical sensitivities:" immunologic critique of clinical ecology theories and practice. , 1987, Occupational medicine.

[56]  D. Stewart,et al.  Psychiatric assessment of patients with "20th-century disease" ("total allergy syndrome"). , 1985, CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne.

[57]  Roger W. Schvaneveldt,et al.  What Is Learned From Artificial Grammars? Transfer Tests of Simple Association , 1994 .

[58]  T. Quill.  Somatization disorder. One of medicine's blind spots. , 1985, JAMA.

[59]  D. Black.  Environmental illness and misdiagnosis--a growing problem. , 1993, Regulatory toxicology and pharmacology : RTP.

[60]  L. Kirmayer,et al.  Current Concepts of Somatization: Research and Clinical Perspectives , 1991 .

[61]  R. Doty,et al.  Olfactory sensitivity, nasal resistance, and autonomic function in patients with multiple chemical sensitivities. , 1988, Archives of otolaryngology--head & neck surgery.

[62]  M. Bleecker,et al.  Conditioning of physical symptoms after neurotoxic exposure. , 1988, Journal of occupational medicine. : official publication of the Industrial Medical Association.

[63]  G. Simon,et al.  Multiple chemical sensitivity syndrome: a clinical perspective. I. Case definition, theories of pathogenesis, and research needs. , 1994, Journal of occupational medicine. : official publication of the Industrial Medical Association.

[64]  Anne E. Figert,et al.  From Paralysis to Fatigue: A History of Psychosomatic Illness in the Modern Era. , 1993 .

[65]  R. Rescorla.  Pavlovian conditioning. It's not what you think it is. , 1988 .

[66]  Allan Collins,et al.  A spreading-activation theory of semantic processing , 1975 .

[67]  E. Callaway,et al.  Learned histamine release. , 1984, Science.