Impact of stressful death or divorce in people with HIV: A prospective examination and the buffering effects of religious coping and social support

This study examined the impact of a stressful death/divorce on psychological and immune outcomes in people with HIV. People with HIV with stressful death/divorce were examined from before the event to up to 12 months later (n = 45); controls were assessed at similar intervals (n = 112). Stressful deaths/divorces were associated with increased viral load and anxiety over time (ps ≤ .014), but not CD4+ or depression. Increased use of religious coping after the stressful death/divorce was associated with slower increases in viral load (p = .010). These data suggest people with HIV should consider the potentially elevated risk of transmission after such events and seek appropriate monitoring and care.

[1]  S. Cole,et al.  Stressful and traumatic life events as disruptors to antiretroviral therapy adherence , 2017, AIDS care.

[2]  J. Coan,et al.  Divorce and health: good data in need of better theory. , 2017, Current opinion in psychology.

[3]  Kjersti Norgård Berntsen,et al.  The relationship between mortality and time since divorce, widowhood or remarriage in Norway. , 2012, Social science & medicine.

[4]  David J. Roelfs,et al.  Meta-analysis of marital dissolution and mortality: reevaluating the intersection of gender and age. , 2012, Social science & medicine.

[5]  R. Kessler,et al.  A multinational study of mental disorders, marriage, and divorce , 2011, Acta psychiatrica Scandinavica.

[6]  W. Breitbart,et al.  Anxiety in terminally ill cancer patients. , 2011, Journal of pain and symptom management.

[7]  M. Glymour,et al.  Widowhood and Mortality: A Meta-Analysis , 2011, PloS one.

[8]  David J. Roelfs,et al.  The rising relative risk of mortality for singles: meta-analysis and meta-regression. , 2011, American journal of epidemiology.

[9]  Anne M Johnson,et al.  Determinants of HIV-1 transmission in men who have sex with men: a combined clinical, epidemiological and phylogenetic approach , 2010, AIDS.

[10]  M. Mugavero,et al.  Incident Stressful and Traumatic Life Events and Human Immunodeficiency Virus Sexual Transmission Risk Behaviors in a Longitudinal, Multisite Cohort Study , 2010, Psychosomatic medicine.

[11]  Timothy B. Smith,et al.  Social Relationships and Mortality Risk: A Meta-analytic Review , 2010, PLoS medicine.

[12]  A. Leonard,et al.  Religious Coping and Physiological, Psychological, Social, and Spiritual Outcomes in Patients with HIV/AIDS: Cross-sectional and Longitudinal Findings , 2010, AIDS and Behavior.

[13]  P. Schnohr,et al.  Major life events increase the risk of stroke but not of myocardial infarction: results from the Copenhagen City Heart Study , 2010, European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology.

[14]  M. Mugavero,et al.  Overload: Impact of Incident Stressful Events on Antiretroviral Medication Adherence and Virologic Failure in a Longitudinal, Multisite Human Immunodeficiency Virus Cohort Study , 2009, Psychosomatic medicine.

[15]  L. Groop,et al.  Stressful Life Events and the Metabolic Syndrome , 2009, Diabetes Care.

[16]  G. Ironson,et al.  Everything Changed: Spiritual Transformation in People with HIV , 2009, International journal of psychiatry in medicine.

[17]  C. Geppert Medicine, Religion, and Health: Where Science and Spirituality Meet , 2009 .

[18]  K. Vedhara,et al.  Adverse psychosocial factors predict poorer prognosis in HIV disease: A meta-analytic review of prospective investigations , 2009, Brain, Behavior, and Immunity.

[19]  C. Potagas,et al.  The Effects of Stressful Life Events on the Course of Multiple Sclerosis: A Review , 2009, The International journal of neuroscience.

[20]  Crystal L. Park,et al.  Religion and Spirituality in Adjustment Following Bereavement: An Integrative Review , 2008, Death studies.

[21]  G. Dellatolas,et al.  Influence of anxiety and reported stressful life events on relapses in multiple sclerosis: a prospective study , 2008, Multiple sclerosis.

[22]  J. Wardle,et al.  Do stress-related psychosocial factors contribute to cancer incidence and survival? , 2008, Nature Clinical Practice Oncology.

[23]  G. Ironson,et al.  Do Positive Psychosocial Factors Predict Disease Progression in HIV-1? A Review of the Evidence , 2008, Psychosomatic medicine.

[24]  M. Swartz,et al.  Relation of lifetime trauma and depressive symptoms to mortality in HIV. , 2007, The American journal of psychiatry.

[25]  Kenya R. Urcuyo,et al.  How stress management improves quality of life after treatment for breast cancer. , 2006, Journal of consulting and clinical psychology.

[26]  P. Cuijpers,et al.  Mood and anxiety disorders in widowhood: A systematic review , 2006, Aging & mental health.

[27]  W. Stroebe,et al.  Does social support help in bereavement , 2005 .

[28]  Crystal L. Park Religion as a Meaning‐Making Framework in Coping with Life Stress , 2005 .

[29]  N. Schneiderman,et al.  Psychosocial Factors Predict CD4 and Viral Load Change in Men and Women With Human Immunodeficiency Virus in the Era of Highly Active Antiretroviral Treatment , 2005, Psychosomatic medicine.

[30]  K. Sikkema,et al.  Development and implementation of a spiritual coping group intervention for adults living with HIV/AIDS: A pilot study , 2005 .

[31]  R. Hays,et al.  Religiousness and spirituality among HIV-infected Americans. , 2005, Journal of palliative medicine.

[32]  K. Sikkema,et al.  Gender, ethnicity and spiritual coping among bereaved HIV-positive individuals , 2005 .

[33]  K. Pargament,et al.  Religion and HIV: A Review of the Literature and Clinical Implications , 2004, Southern medical journal.

[34]  S. Segerstrom,et al.  Psychological stress and the human immune system: a meta-analytic study of 30 years of inquiry. , 2004, Psychological bulletin.

[35]  M. Zeegers,et al.  The association between stressful life events and breast cancer risk: A meta‐analysis , 2003, International journal of cancer.

[36]  Gail Ironson,et al.  A short social support measure for patients recovering from myocardial infarction: the ENRICHD Social Support Inventory. , 2003, Journal of cardiopulmonary rehabilitation.

[37]  J. Singer,et al.  Doing Data Analysis with the Multilevel Model for Change , 2003 .

[38]  H. Gu,et al.  Progression to AIDS, a clinical AIDS condition and mortality: psychosocial and physiological predictors , 2002, Psychological Medicine.

[39]  A. Wu,et al.  Self-reported adherence to antiretroviral medications among participants in HIV clinical trials: The AACTG Adherence Instruments , 2000, AIDS care.

[40]  M. Bourassa,et al.  Social support, depression, and mortality during the first year after myocardial infarction. , 2000, Circulation.

[41]  S. Folkman,et al.  Spiritual aspects of loss among partners of men with AIDS: postbereavement follow-up. , 1999, Death studies.

[42]  L. Kaldjian,et al.  End‐of‐life decisions in HIV‐positive patients: the role of spiritual beliefs , 1998, AIDS.

[43]  P. Leaf,et al.  Depressive episodes and dysphoria resulting from conjugal bereavement in a prospective community sample. , 1990, The American journal of psychiatry.

[44]  James H. Johnson,et al.  Assessing the impact of life changes: development of the Life Experiences Survey. , 1978, Journal of consulting and clinical psychology.

[45]  A. Beck,et al.  An inventory for measuring depression. , 1961, Archives of general psychiatry.

[46]  K. Pargament,et al.  Integrating Religion and Spirituality Into Treatment Research and Practice , 2015 .

[47]  Jacqueline Thompson The Oxford Handbook of Stress, Health and Coping , 2012 .

[48]  L. Groop,et al.  Stressful Life Events and the Metabolic Syndrome - The Prevalence, Prediction and Prevention of Diabetes (PPP)-Botnia Study , 2010 .

[49]  N. Schneiderman,et al.  Cognitive-behavioral stress management intervention effects on anxiety, 24-hr urinary norepinephrine output, and T-cytotoxic/suppressor cells over time among symptomatic HIV-infected gay men. , 2000, Journal of consulting and clinical psychology.

[50]  C. Carver You want to measure coping but your protocol’ too long: Consider the brief cope , 1997, International journal of behavioral medicine.

[51]  M. Kemeny,et al.  Effects of AIDS-related bereavement on HIV progression among New York City gay men. , 1995, AIDS education and prevention : official publication of the International Society for AIDS Education.

[52]  C. Spielberger,et al.  Manual for the State-Trait Anxiety Inventory , 1970 .