Biochemical and biological activities of the venom of the Chinese pitviper Zhaoermia mangshanensis, with the complete amino acid sequence and phylogenetic analysis of a novel Arg49 phospholipase A2 myotoxin.

[1]  J. Gutiérrez,et al.  Myotoxic and cytolytic activities of dimeric Lys49 phospholipase A2 homologues are reduced, but not abolished, by a pH-induced dissociation. , 2005, Toxicon : official journal of the International Society on Toxinology.

[2]  K. Abe,et al.  Amino acid sequence of a basic aspartate-49-phospholipase A2 from Trimeresurus flavoviridis venom and phylogenetic analysis of Crotalinae venom phospholipases A2. , 2005, Toxicon : official journal of the International Society on Toxinology.

[3]  Edgardo Moreno,et al.  Antimicrobial activity of myotoxic phospholipases A2 from crotalid snake venoms and synthetic peptide variants derived from their C-terminal region. , 2005, Toxicon : official journal of the International Society on Toxinology.

[4]  David Posada,et al.  ProtTest: selection of best-fit models of protein evolution , 2005, Bioinform..

[5]  J. Gutiérrez,et al.  Inflammatory events induced by Lys-49 and Asp-49 phospholipases A2 isolated from Bothrops asper snake venom: role of catalytic activity. , 2005, Toxicon : official journal of the International Society on Toxinology.

[6]  Michael P. Cummings,et al.  PAUP* [Phylogenetic Analysis Using Parsimony (and Other Methods)] , 2004 .

[7]  I. Tsai,et al.  Comparative proteomics and subtyping of venom phospholipases A2 and disintegrins of Protobothrops pit vipers. , 2004, Biochimica et biophysica acta.

[8]  D. Posada,et al.  Model selection and model averaging in phylogenetics: advantages of akaike information criterion and bayesian approaches over likelihood ratio tests. , 2004, Systematic biology.

[9]  A. Malhotra,et al.  A phylogeny of four mitochondrial gene regions suggests a revised taxonomy for Asian pitvipers (Trimeresurus and Ovophis). , 2004, Molecular phylogenetics and evolution.

[10]  A. Malhotra,et al.  REDESCRIPTION AND SYSTEMATICS OF TRIMERESURUS CORNUTUS (SERPENTES: VIPERIDAE) BASED ON MORPHOLOGY AND MOLECULAR DATA , 2004 .

[11]  L. Possani,et al.  Phaiodactylipin, a glycosylated heterodimeric phospholipase A from the venom of the scorpion Anuroctonus phaiodactylus. , 2004, European journal of biochemistry.

[12]  Y. Sakaki,et al.  Molecular evolution of group II phospholipases A2 , 1995, Journal of Molecular Evolution.

[13]  M. Paine,et al.  The molecular cloning of a phospholipase A2 from Bothrops jararacussu snake venom: Evolution of venom group II phospholipase A2's may imply gene duplications , 1995, Journal of Molecular Evolution.

[14]  I. Tsai,et al.  Venom phospholipases A2 of bamboo viper (Trimeresurus stejnegeri): molecular characterization, geographic variations and evidence of multiple ancestries. , 2004, The Biochemical journal.

[15]  J. Gutiérrez,et al.  Skeletal muscle degeneration induced by venom phospholipases A2: insights into the mechanisms of local and systemic myotoxicity. , 2003, Toxicon : official journal of the International Society on Toxinology.

[16]  C. Teixeira,et al.  Inflammatory effects of snake venom myotoxic phospholipases A2. , 2003, Toxicon : official journal of the International Society on Toxinology.

[17]  M. Ohno,et al.  Molecular evolution of myotoxic phospholipases A2 from snake venom. , 2003, Toxicon : official journal of the International Society on Toxinology.

[18]  R. Ward,et al.  Mapping structural determinants of biological activities in snake venom phospholipases A2 by sequence analysis and site directed mutagenesis. , 2003, Toxicon : official journal of the International Society on Toxinology.

[19]  B. Lomonte,et al.  An overview of lysine-49 phospholipase A2 myotoxins from crotalid snake venoms and their structural determinants of myotoxic action. , 2003, Toxicon : official journal of the International Society on Toxinology.

[20]  M. Ohno,et al.  Interisland Mutation of a Novel Phospholipase A2 from Trimeresurus flavoviridis Venom and Evolution of Crotalinae Group II Phospholipases A2 , 2003, Journal of Molecular Evolution.

[21]  C. Santamaria,et al.  Comparative study of synthetic peptides corresponding to region 115-129 in Lys49 myotoxic phospholipases A2 from snake venoms. , 2003, Toxicon : official journal of the International Society on Toxinology.

[22]  John P. Huelsenbeck,et al.  MrBayes 3: Bayesian phylogenetic inference under mixed models , 2003, Bioinform..

[23]  M. Holder,et al.  Phylogeny estimation: traditional and Bayesian approaches , 2003, Nature Reviews Genetics.

[24]  U. Kuch,et al.  Biochemical and biological activities of the venom of a new species of pitviper from Vietnam, Triceratolepidophis sieversorum. , 2003, Toxicon : official journal of the International Society on Toxinology.

[25]  R. C. Rodríguez de la Vega,et al.  Two novel toxins from the Amazonian scorpion Tityus cambridgei that block Kv1.3 and Shaker B K(+)-channels with distinctly different affinities. , 2002, Biochimica et biophysica acta.

[26]  R. Ward,et al.  Distinct sites for myotoxic and membrane-damaging activities in the C-terminal region of a Lys49-phospholipase A2. , 2002, The Biochemical journal.

[27]  R. Ward,et al.  biological and membrane-disrupting activities in the absence of catalysis , 2002 .

[28]  Wan-yu Wang,et al.  Biochemical and biological properties of Trimeresurus jerdonii venom and characterization of a platelet aggregation-inhibiting acidic phospholipase A2. , 2002, Journal of natural toxins.

[29]  Jonathan P. Bollback,et al.  Bayesian Inference of Phylogeny and Its Impact on Evolutionary Biology , 2001, Science.

[30]  John P. Huelsenbeck,et al.  MRBAYES: Bayesian inference of phylogenetic trees , 2001, Bioinform..

[31]  R. Ward,et al.  The effect of resonance energy homotransfer on the intrinsic tryptophan fluorescence emission of the bothropstoxin-I dimer. , 2001, Biochemical and biophysical research communications.

[32]  S. Whelan,et al.  A general empirical model of protein evolution derived from multiple protein families using a maximum-likelihood approach. , 2001, Molecular biology and evolution.

[33]  S Marangoni,et al.  Structural basis for low catalytic activity in Lys49 phospholipases A2--a hypothesis: the crystal structure of piratoxin II complexed to fatty acid. , 2001, Biochemistry.

[34]  J. Huelsenbeck,et al.  MRBAYES : Bayesian inference of phylogeny , 2001 .

[35]  I. Tsai,et al.  Phospholipases A2 from Callosellasma rhodostoma venom gland cloning and sequencing of 10 of the cDNAs, three-dimensional modelling and chemical modification of the major isozyme. , 2000, European journal of biochemistry.

[36]  X. Wu,et al.  Diversity of cDNAs encoding phospholipase A2 from Agkistrodon halys pallas venom, and its expression in E. coli. , 1998, Toxicon : official journal of the International Society on Toxinology.

[37]  G. Casari,et al.  A SequenceSpace analysis of Lys49 phopholipases A2: clues towards identification of residues involved in a novel mechanism of membrane damage and in myotoxicity. , 1998, Protein engineering.

[38]  G. Oliva,et al.  Crystallographic and spectroscopic characterization of a molecular hinge: Conformational changes in bothropstoxin I, a dimeric Lys49‐phospholipase A2 homologue , 1998, Proteins.

[39]  W. Y. Wang,et al.  Characterization of a fibrinogen-clotting enzyme from Trimeresurus stejnegeri venom, and comparative study with other venom proteases. , 1998, Toxicon : official journal of the International Society on Toxinology.

[40]  H. Eklund,et al.  The three-dimensional structures of two toxins from snake venom throw light on the anticoagulant and neurotoxic sites of phospholipase A2. , 1998, Toxicon : official journal of the International Society on Toxinology.

[41]  J. Thompson,et al.  The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools. , 1997, Nucleic acids research.

[42]  Thomas L. Madden,et al.  Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. , 1997, Nucleic acids research.

[43]  Haiyan Tong,et al.  Translations of Recent Descriptions of Chinese Pitvipers of the Trimeresurus-Complex (Serpentes, Viperidae), with a Key to the Complex in China and Adjacent Areas , 1997 .

[44]  M. Peitsch,et al.  Asp-49 is not an absolute prerequisite for the enzymic activity of low-M(r) phospholipases A2: purification, characterization and computer modelling of an enzymically active Ser-49 phospholipase A2, ecarpholin S, from the venom of Echis carinatus sochureki (saw-scaled viper). , 1996, The Biochemical journal.

[45]  R. Arni,et al.  Phospholipase A2--a structural review. , 1996, Toxicon : official journal of the International Society on Toxinology.

[46]  J. Gutiérrez,et al.  Phospholipase A2 myotoxins from Bothrops snake venoms. , 1995, Toxicon : official journal of the International Society on Toxinology.

[47]  M. Hattori,et al.  Accelerated evolution in the protein-coding regions is universal in crotalinae snake venom gland phospholipase A2 isozyme genes. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[48]  C. Ownby,et al.  Fractionation of Bothrops pirajai snake venom: isolation and characterization of piratoxin-I, a new myotoxic protein. , 1995, Toxicon : official journal of the International Society on Toxinology.

[49]  R. Arni,et al.  Crystallization and preliminary diffraction data of bothropstoxin I isolated from the venom of Bothrops jararacussu. , 1995, Toxicon : official journal of the International Society on Toxinology.

[50]  A. Tulinsky,et al.  Structure of a calcium-independent phospholipase-like myotoxic protein from Bothrops asper venom. , 1994, Acta crystallographica. Section D, Biological crystallography.

[51]  B. Lomonte,et al.  Neutralizing interaction between heparins and myotoxin II, a lysine 49 phospholipase A2 from Bothrops asper snake venom. Identification of a heparin-binding and cytolytic toxin region by the use of synthetic peptides and molecular modeling. , 1994, The Journal of biological chemistry.

[52]  J. Gutiérrez,et al.  Cleavage of the NH2-terminal octapeptide of Bothrops asper myotoxic lysine-49 phospholipase A2 reduces its membrane-destabilizing effect. , 1994, Archives of biochemistry and biophysics.

[53]  B. Johansson,et al.  The dynamics of local tissue damage induced by Bothrops asper snake venom and myotoxin II on the mouse cremaster muscle: an intravital and electron microscopic study. , 1994, Toxicon : official journal of the International Society on Toxinology.

[54]  E. Veldhuizen,et al.  Acylation of porcine pancreatic phospholipase A2 influences penetration and substrate head-group binding, depending on the position of the acylated lysine in the enzyme molecule. , 1993, European journal of biochemistry.

[55]  B. Lomonte,et al.  Host response to Bothrops asper snake venom. Analysis of edema formation, inflammatory cells, and cytokine release in a mouse model. , 1993, Inflammation.

[56]  I. Reardon,et al.  An examination of structural interactions presumed to be of importance in the stabilization of phospholipase A2 dimers based upon comparative protein sequence analysis of a monomeric and dimeric enzyme from the venom ofAgkistrodon p. piscivorus , 1993, Journal of protein chemistry.

[57]  C. Ownby,et al.  Isolation of a myotoxin from the venom of Agkistrodon contortrix laticinctus (broad-banded copperhead) and pathogenesis of myonecrosis induced by it in mice. , 1993, Toxicon : official journal of the International Society on Toxinology.

[58]  S. Marangoni,et al.  Bothropstoxin-I: Amino acid sequence and function , 1993, Journal of protein chemistry.

[59]  R. Heinrikson,et al.  The lysine-49 phospholipase A2 from the venom of Agkistrodon piscivorus piscivorus. Relation of structure and function to other phospholipases A2. , 1986, The Journal of biological chemistry.

[60]  E. D. Brodie,et al.  Biology of the Pitvipers , 1992 .

[61]  I. Križaj,et al.  The primary structure of ammodytin L, a myotoxic phospholipase A2 homologue from Vipera ammodytes venom. , 1991, European journal of biochemistry.

[62]  I. Tsai,et al.  The amino acid sequence and properties of an edema-inducing Lys-49 phospholipase A2 homolog from the venom of Trimeresurus mucrosquamatus. , 1991, Biochimica et biophysica acta.

[63]  J. Gutiérrez,et al.  Myotoxin II from Bothrops asper (Terciopelo) venom is a lysine-49 phospholipase A2. , 1991, Archives of biochemistry and biophysics.

[64]  J. Gutiérrez,et al.  The amino acid sequence of a myotoxic phospholipase from the venom of Bothrops asper. , 1990, Archives of biochemistry and biophysics.

[65]  C. Ownby,et al.  Myotoxic components of snake venoms: their biochemical and biological activities. , 1990, Pharmacology & therapeutics.

[66]  R. Kini,et al.  A common cytolytic region in myotoxins, hemolysins, cardiotoxins and antibacterial peptides. , 2009, International journal of peptide and protein research.

[67]  D. Turk,et al.  Primary structure of ammodytoxin C further reveals the toxic site of ammodytoxin. , 1989, Biochimica et biophysica acta.

[68]  D. Mebs,et al.  Cross-neutralization of thrombin-like enzymes in snake venoms by polyvalent antivenoms. , 1989, Toxicon : official journal of the International Society on Toxinology.

[69]  A. Armugam,et al.  A comparative study of the enzymatic and toxic properties of venoms of the Asian lance-headed pit viper (Genus Trimeresurus). , 1989, Comparative biochemistry and physiology. B, Comparative biochemistry.

[70]  L. Rodrigues-Simioni,et al.  Fractionation of Bothrops jararacussu snake venom: partial chemical characterization and biological activity of bothropstoxin. , 1988, Toxicon : official journal of the International Society on Toxinology.

[71]  V. Turk,et al.  Amino-acid sequence of ammodytoxin B partially reveals the location of the site of toxicity of ammodytoxins. , 1986, Biological chemistry Hoppe-Seyler.

[72]  P B Sigler,et al.  The refined crystal structure of dimeric phospholipase A2 at 2.5 A. Access to a shielded catalytic center. , 1986 .

[73]  J. Drenth,et al.  A comparison of the crystal structures of phospholipase A2 from bovine pancreas and Crotalus atrox venom. , 1985, The Journal of biological chemistry.

[74]  F. Gubensek,et al.  Ammodytoxin A, a highly lethal phospholipase A2 from Vipera ammodytes ammodytes venom. , 1985, Biochimica et biophysica acta.

[75]  R. Heinrikson,et al.  A new class of phospholipases A2 with lysine in place of aspartate 49. Functional consequences for calcium and substrate binding. , 1984, The Journal of biological chemistry.

[76]  J. M. Gutiérrez,et al.  Mecanismo de accion de miotoxinas aisladas de venenos de serpientes , 1984 .

[77]  R. Heinrikson,et al.  Crotalus atrox phospholipase A2. Amino acid sequence and studies on the function of the NH2-terminal region. , 1982, The Journal of biological chemistry.

[78]  A. Mcintosh,et al.  The International Code of Zoological Nomenclature , 1962, Journal of the Marine Biological Association of the United Kingdom.

[79]  W. Kocholaty,et al.  Toxicity and some enzymatic properties and activities in the venoms of Crotalidae, Elapidae and Viperidae. , 1971, Toxicon : official journal of the International Society on Toxinology.

[80]  U. K. Laemmli,et al.  Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4 , 1970, Nature.

[81]  D. Mebs.  A comparative study of enzyme activities in snake venoms , 1970 .

[82]  G. Marinetti.  The action of phospholipase A on lipoproteins. , 1965, Biochimica et biophysica acta.

[83]  G. Schwert,et al.  A spectrophotometric determination of trypsin and chymotrypsin. , 1955, Biochimica et biophysica acta.