Concise drug review: azacitidine and decitabine.
暂无分享,去创建一个
[1] M. Carducci,et al. Quantification of 5-azacytidine in plasma by electrospray tandem mass spectrometry coupled with high-performance liquid chromatography. , 2004, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
[2] H. Kantarjian,et al. Epigenetic therapy is associated with similar survival compared with intensive chemotherapy in older patients with newly diagnosed acute myeloid leukemia. , 2012, Blood.
[3] J. Issa,et al. Activity of decitabine in patients with myelodysplastic syndrome previously treated with azacitidine , 2008, Leukemia & lymphoma.
[4] M. Beran. Intensive chemotherapy for patients with high-risk myelodysplastic syndrome. , 2000, International journal of hematology.
[5] G. Mufti,et al. Continued azacitidine therapy beyond time of first response improves quality of response in patients with higher‐risk myelodysplastic syndromes , 2011, Cancer.
[6] M. Lübbert,et al. Superiority of prolonged low‐dose azanucleoside administration? , 2006, Cancer.
[7] J. Pirkle,et al. The disposition and pharmacokinetics in humans of 5-azacytidine administered intravenously as a bolus or by continuous infusion. , 1976, Cancer research.
[8] G. Marcucci,et al. Bioavailability of Azacitidine Subcutaneous Versus Intravenous in Patients With the Myelodysplastic Syndromes , 2005, Journal of clinical pharmacology.
[9] M. T. McCabe,et al. Cancer DNA Methylation: Molecular Mechanisms and Clinical Implications , 2009, Clinical Cancer Research.
[10] B. Quesnel,et al. Impact of TET2 mutations on response rate to azacitidine in myelodysplastic syndromes and low blast count acute myeloid leukemias , 2011, Leukemia.
[11] M. T. McCabe,et al. Cancer DNAMethylation : Molecular Mechanisms and Clinical Implications , 2009 .
[12] P. Fenaux,et al. Predicting the outcome of patients with higher-risk myelodysplastic syndrome treated with hypomethylating agents , 2012, Leukemia & lymphoma.
[13] A. Stamatoullas,et al. Prognostic factors for response and overall survival in 282 patients with higher-risk myelodysplastic syndromes treated with azacitidine. , 2011, Blood.
[14] John M Bennett,et al. Decitabine improves patient outcomes in myelodysplastic syndromes , 2006, Cancer.
[15] J. Issa,et al. Update of the decitabine experience in higher risk myelodysplastic syndrome and analysis of prognostic factors associated with outcome , 2007, Cancer.
[16] B. Esterni,et al. Outcome of acute myeloid leukaemia following myelodysplastic syndrome after azacitidine treatment failure , 2012, British journal of haematology.
[17] P. Fenaux,et al. Optimizing hypomethylating agents in myelodysplastic syndromes , 2012, Current opinion in hematology.
[18] J. Christman,et al. 5-Azacytidine and 5-aza-2′-deoxycytidine as inhibitors of DNA methylation: mechanistic studies and their implications for cancer therapy , 2002, Oncogene.
[19] J. Maciejewski,et al. Phase 2 study of the lenalidomide and azacitidine combination in patients with higher-risk myelodysplastic syndromes. , 2012, Blood.
[20] J. Holland,et al. Randomized controlled trial of azacitidine in patients with the myelodysplastic syndrome: a study of the cancer and leukemia group B. , 2002, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[21] B. Esterni,et al. Outcome of high-risk myelodysplastic syndrome after azacitidine treatment failure. , 2011, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[22] G. Mufti,et al. Management and supportive care measures for adverse events in patients with myelodysplastic syndromes treated with azacitidine * , 2010, European journal of haematology.
[23] H. Kantarjian,et al. Multicenter study of decitabine administered daily for 5 days every 4 weeks to adults with myelodysplastic syndromes: the alternative dosing for outpatient treatment (ADOPT) trial. , 2009, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[24] J. Stambaugh,et al. Absorption, distribution, and excretion of 5-azacytidine (NSC-102816) in man. , 1972, Cancer chemotherapy reports.
[25] F. Lyko,et al. Modes of action of the DNA methyltransferase inhibitors azacytidine and decitabine , 2008, International journal of cancer.
[26] S. Guichard,et al. Simultaneous determination of decitabine and vorinostat (Suberoylanalide hydroxamic acid, SAHA) by liquid chromatography tandem mass spectrometry for clinical studies. , 2008, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
[27] J. Hainsworth,et al. Hematologic response to three alternative dosing schedules of azacitidine in patients with myelodysplastic syndromes. , 2009, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[28] J. Issa,et al. Feasibility of therapy with hypomethylating agents in patients with renal insufficiency. , 2010, Clinical lymphoma, myeloma & leukemia.
[29] In vitro assessment of cytochrome P450 inhibition and induction potential of azacitidine , 2010, Cancer Chemotherapy and Pharmacology.
[30] J. Issa,et al. Targeting DNA Methylation , 2009, Clinical Cancer Research.
[31] B. Cheson,et al. Clinical application and proposal for modification of the International Working Group (IWG) response criteria in myelodysplasia. , 2006, Blood.
[32] M. Mancini,et al. Application of French prognostic score to patients with International Prognostic Scoring System intermediate-2 or high risk myelodysplastic syndromes treated with 5-azacitidine is able to predict overall survival and rate of response , 2012, Leukemia & lymphoma.
[33] J. Issa,et al. Outcome of patients with myelodysplastic syndrome after failure of decitabine therapy , 2010, Cancer.
[34] M. Minden,et al. Multicenter, randomized, open-label, phase III trial of decitabine versus patient choice, with physician advice, of either supportive care or low-dose cytarabine for the treatment of older patients with newly diagnosed acute myeloid leukemia. , 2012, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[35] R. Larson,et al. Further analysis of trials with azacitidine in patients with myelodysplastic syndrome: studies 8421, 8921, and 9221 by the Cancer and Leukemia Group B. , 2006, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[36] Valeria Santini,et al. Efficacy of azacitidine compared with that of conventional care regimens in the treatment of higher-risk myelodysplastic syndromes: a randomised, open-label, phase III study. , 2009, The Lancet. Oncology.
[37] J. Issa. Epigenetic changes in the myelodysplastic syndrome. , 2010, Hematology/oncology clinics of North America.
[38] E. Vellenga,et al. Platelet doubling after the first azacitidine cycle is a promising predictor for response in myelodysplastic syndromes (MDS), chronic myelomonocytic leukaemia (CMML) and acute myeloid leukaemia (AML) patients in the Dutch azacitidine compassionate named patient programme , 2011, British journal of haematology.
[39] J. Dipersio,et al. Pharmacokinetics of decitabine administered as a 3-h infusion to patients with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) , 2008, Cancer Chemotherapy and Pharmacology.