N,C-Capped dipeptides with selectivity for mycobacterial proteasome over human proteasomes: role of S3 and S1 binding pockets.
暂无分享,去创建一个
M. Sintchak | L. Dick | C. Nathan | C. Blackburn | K. Gigstad | Julien Vaubourgeix | C. Tsu | Thulasi Warrier | G. Lin | Tamutenda Chidawanyika
[1] Ricarda Schwab,et al. Immuno- and Constitutive Proteasome Crystal Structures Reveal Differences in Substrate and Inhibitor Specificity , 2012, Cell.
[2] P. Kloetzel,et al. Immunoproteasomes at the interface of innate and adaptive immune responses: two faces of one enzyme. , 2012, Current opinion in immunology.
[3] K. Rock,et al. Mice completely lacking immunoproteasomes display major alterations in antigen presentation , 2011, Nature Immunology.
[4] T. Soucy,et al. Characterization of a new series of non-covalent proteasome inhibitors with exquisite potency and selectivity for the 20S β5-subunit , 2010, The Biochemical journal.
[5] S. Gandotra,et al. The Mycobacterium tuberculosis Proteasome Active Site Threonine Is Essential for Persistence Yet Dispensable for Replication and Resistance to Nitric Oxide , 2010, PLoS pathogens.
[6] Huilin Li,et al. Inhibitors Selective for Mycobacterial versus Human Proteasomes , 2009, Nature.
[7] L. Dick,et al. Distinct Specificities of Mycobacterium tuberculosis and Mammalian Proteasomes for N-Acetyl Tripeptide Substrates* , 2008, Journal of Biological Chemistry.
[8] C. Nathan,et al. A philosophy of anti-infectives as a guide in the search for new drugs for tuberculosis. , 2008, Tuberculosis.
[9] M. Gurney,et al. Selective killing of nonreplicating mycobacteria. , 2008, Cell host & microbe.
[10] W. Hillen,et al. In vivo gene silencing identifies the Mycobacterium tuberculosis proteasome as essential for the bacteria to persist in mice , 2007, Nature Medicine.
[11] Carl Nathan,et al. Role of iNOS in Human Host Defense , 2006, Science.
[12] T. Parsons,et al. Mycobacterium tuberculosis prcBA genes encode a gated proteasome with broad oligopeptide specificity , 2006, Molecular microbiology.
[13] C. Nathan,et al. The Proteasome of Mycobacterium tuberculosis Is Required for Resistance to Nitric Oxide , 2003, Science.
[14] Wolfgang Baumeister,et al. The Proteasome: Paradigm of a Self-Compartmentalizing Protease , 1998, Cell.
[15] J. Mudgett,et al. Identification of nitric oxide synthase as a protective locus against tuberculosis. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[16] S. Beck,et al. Second proteasome-related gene in the human MHC class II region , 1991, Nature.
[17] S. Beck,et al. A proteasome-related gene between the two ABC transporter loci in the class II region of the human MHC , 1991, Nature.
[18] J. Monaco,et al. Structural and serological similarity of MHC-linked LMP and proteasome (multicatalytic proteinase) complexes , 1991, Nature.