Rotationally constrained 2,4-diamino-5,6-disubstituted pyrimidines: a new class of histamine H4 receptor antagonists with improved druglikeness and in vivo efficacy in pain and inflammation models.
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Jill M. Wetter | M. McPherson | J. Sullivan | J. Brioni | P. Honore | K. Marsh | N. Wishart | G. Hsieh | T. Esbenshade | M. Cowart | T. Miller | Ivan Milicic | D. Witte | Huaqing Liu | I. Drizin | R. Altenbach | B. Bettencourt | Shannon R. Fix-Stenzel | R. M. Adair