A portable three-channel data collector for Chinese medicine pulses

Abstract Visualization of traditional Chinese medicine (TCM) could offer an opportunity for doctors and patients have a perspective of life and health, while TCM visualization is difficult to achieve because large amounts of pulse data needed to be collected for big data analyses and diagnoses. However, existing data-collecting devices still don’t have the ability to substitute for doctor’s fingers to accurately recognize the pulse signals from the different positions on different genders and ages of detecting objects, under different levels and directions of applied forces. Herein, we introduce a portable three-channel data collector on a human hand as a transitional scheme for visualization of TCM to make use of human fingers’ flexibility. This data collector was made up of three homemade flexible pressure sensors, three-channel transmitting circuit, and a signal processing software, in which the sensors fabricated by conductive carbon fiber beams were present high-sensitivity and reliability, make them suitable for the monitoring of pulse signals. Comprehensive researches and analyses on the pulse signals further demonstrated that this portable three-channel data collector could accurately capture and identifying the slightly distinctions of radial artery pulse waves under different positions, different level forces, different directions of applied forces, different genders and ages of detected objects. Moreover, this three-channel data collector has been successfully applied to remote TCM diagnosis, indicated that the data collector could be a promising personal medical equipment for the application of TCM visualization.

[1]  Joanne W Y Chung,et al.  Digitalizing traditional chinese medicine pulse diagnosis with artificial neural network. , 2012, Telemedicine journal and e-health : the official journal of the American Telemedicine Association.

[2]  Guoning Chen,et al.  Identifying human body states by using a flexible integrated sensor , 2020, npj Flexible Electronics.

[3]  J. Portnoy,et al.  Telemedicine in the Era of COVID-19 , 2020, The Journal of Allergy and Clinical Immunology: In Practice.

[4]  Xin Jiang,et al.  A Wearable and Highly Sensitive Graphene Strain Sensor for Precise Home-Based Pulse Wave Monitoring. , 2017, ACS sensors.

[5]  Xiaodong Chen,et al.  A Carbon Flower Based Flexible Pressure Sensor Made from Large‐Area Coating , 2020, Advanced Materials Interfaces.

[6]  Yinji Ma,et al.  Ultralow-Cost, Highly Sensitive, and Flexible Pressure Sensors Based on Carbon Black and Airlaid Paper for Wearable Electronics. , 2019, ACS applied materials & interfaces.

[7]  Jason Jianjun Gu,et al.  Detection of multipoint pulse waves and dynamic 3D pulse shape of the radial artery based on binocular vision theory , 2018, Comput. Methods Programs Biomed..

[8]  Pekka Kostiainen,et al.  Clinical assessment of a non-invasive wearable MEMS pressure sensor array for monitoring of arterial pulse waveform, heart rate and detection of atrial fibrillation , 2019, npj Digital Medicine.

[9]  Guojun Wang,et al.  A multimodal deep architecture for traditional Chinese medicine diagnosis , 2020, Concurr. Comput. Pract. Exp..

[10]  Qiyuan He,et al.  Sensitive pressure sensors based on conductive microstructured air-gap gates and two-dimensional semiconductor transistors , 2020 .

[11]  M. Manco‐Johnson,et al.  Prevalence of clinical hip abnormalities in haemophilia A and B: an analysis of the UDC database , 2013, Haemophilia : the official journal of the World Federation of Hemophilia.

[12]  Bo Peng,et al.  Recent Advances in Nanomaterial-Enabled Wearable Sensors: Material Synthesis, Sensor Design, and Personal Health Monitoring. , 2020, Small.

[13]  Shabana Urooj,et al.  Design of Quad-Port MIMO/Diversity Antenna with Triple-Band Elimination Characteristics for Super-Wideband Applications , 2020, Sensors.

[14]  Ying Chen,et al.  High‐Performance Flexible Tactile Sensor Enabling Intelligent Haptic Perception for a Soft Prosthetic Hand , 2019, Advanced Materials Technologies.

[15]  David Zhang,et al.  A robust signal preprocessing framework for wrist pulse analysis , 2016, Biomed. Signal Process. Control..

[16]  Yong Su,et al.  Full-field wrist pulse signal acquisition and analysis by 3D Digital Image Correlation , 2017 .

[17]  David Zhang,et al.  A Robust Wrist Pulse Acquisition System Based on Multisensor Collaboration and Signal Quality Assessment , 2019, IEEE Transactions on Instrumentation and Measurement.

[18]  Liwei Lin,et al.  Human Pulse Diagnosis for Medical Assessments Using a Wearable Piezoelectret Sensing System , 2018, Advanced Functional Materials.

[19]  Hwa-Yaw Tam,et al.  Measurement of Pulse Wave Signals and Blood Pressure by a Plastic Optical Fiber FBG Sensor , 2019, Sensors.

[20]  Minjeong Ha,et al.  Wearable and flexible sensors for user-interactive health-monitoring devices. , 2018, Journal of materials chemistry. B.

[21]  Jun Zhang,et al.  A novel flexible pressure sensor array for depth information of radial artery , 2017 .

[22]  Weidong Yu,et al.  Silk Composite Electronic Textile Sensor for High Space Precision 2D Combo Temperature-Pressure Sensing. , 2019, Small.

[23]  Ching-Hsing Luo,et al.  Using an array sensor to determine differences in pulse diagnosis—Three positions and nine indicators , 2014 .

[24]  Bokolo Anthony Jnr..  Use of Telemedicine and Virtual Care for Remote Treatment in Response to COVID-19 Pandemic. , 2020 .

[25]  David Zhang,et al.  A Compound Pressure Signal Acquisition System for Multichannel Wrist Pulse Signal Analysis , 2014, IEEE Transactions on Instrumentation and Measurement.

[26]  Ching-Hsing Luo,et al.  Temporal and Spatial Properties of Arterial Pulsation Measurement Using Pressure Sensor Array , 2011, Evidence-based complementary and alternative medicine : eCAM.

[27]  Zheng Liu,et al.  Flexible Sensing Electronics for Wearable/Attachable Health Monitoring. , 2017, Small.

[28]  R. Sun,et al.  Flexible and Highly Sensitive Pressure Sensor Based on Microdome-Patterned PDMS Forming with Assistance of Colloid Self-Assembly and Replica Technique for Wearable Electronics. , 2017, ACS applied materials & interfaces.

[29]  Guoning Chen,et al.  Flexible Integrated Sensors: Transverse Piezoresistance and Longitudinal Thermal Resistance of One Single Carbon Fiber Beam , 2019, Advanced Materials Technologies.

[30]  R. Zhu,et al.  High Sensitivity and Broad Range Flexible Pressure Sensor Using Multilayered Porous PDMS/AgNP Sponge , 2019, Advanced Materials Technologies.

[31]  Chang Kyu Jeong,et al.  Self‐Powered Real‐Time Arterial Pulse Monitoring Using Ultrathin Epidermal Piezoelectric Sensors , 2017, Advanced materials.

[32]  Yan Wang,et al.  Highly Sensitive Flexible Iontronic Pressure Sensor for Fingertip Pulse Monitoring , 2020, Advanced healthcare materials.

[33]  Zhen Qi,et al.  The Association of Radial Artery Pulse Wave Variables with the Pulse Wave Velocity and Echocardiographic Parameters in Hypertension , 2018, Evidence-based complementary and alternative medicine : eCAM.

[34]  R. Zhu,et al.  A Wearable Sensor Using Structured Silver‐Particle Reinforced PDMS for Radial Arterial Pulse Wave Monitoring , 2019, Advanced healthcare materials.

[35]  Kai Zhao,et al.  A pneumonia outbreak associated with a new coronavirus of probable bat origin , 2020, Nature.

[36]  Yu-Feng Chung,et al.  Possibility of quantifying TCM finger-reading sensations: I. Bi-Sensing Pulse Diagnosis Instrument , 2012 .

[37]  K. Asayama,et al.  Recent status of self-measured home blood pressure in the Japanese general population: a modern database on self-measured home blood pressure (MDAS) , 2020, Hypertension Research.

[38]  Wei Lu,et al.  A Universal high accuracy wearable pulse monitoring system via high sensitivity and large linearity graphene pressure sensor , 2019, Nano Energy.

[39]  Zhong Lin Wang,et al.  Flexible Weaving Constructed Self‐Powered Pressure Sensor Enabling Continuous Diagnosis of Cardiovascular Disease and Measurement of Cuffless Blood Pressure , 2018, Advanced Functional Materials.

[40]  P. Chapuis,et al.  Comparing the Batch and Flow Syntheses of Metal Ammonium Phosphates: A Green Chemistry Approach , 2021, 2110.09781.

[41]  Haiying Zhang,et al.  A 3D Wrist Pulse Signal Acquisition System for Width Information of Pulse Wave , 2019, Sensors.

[42]  X. Ye,et al.  Towards ultra-wide operation range and high sensitivity: Graphene film based pressure sensors for fingertips. , 2019, Biosensors & bioelectronics.