Frequency-Dependent Effects of Class III Antiarrhythmic Agents as Assessed by MAP Recordings — Possible Advantages of lKs Blockade

[1]  A. Schömig,et al.  Differential Effect of β‐Adrenergic Stimulation on the Frequency‐Dependent Electrophysiologic Actions of the New Class III Antiarrhythmics Dofetilide, Ambasilide, and Chromanol 293. , 1997 .

[2]  B. Singh,et al.  The coming of age of the class III antiarrhythmic principle: retrospective and future trends. , 1996, The American journal of cardiology.

[3]  R. Lazzara,et al.  Electrophysiological and inotropic characterization of a novel class III antiarrhythmic agent, GLG-V-13, in the mammalian heart. , 1996, Journal of cardiovascular pharmacology.

[4]  A. Schömig,et al.  Differential class III antiarrhythmic effects of ambasilide and dofetilide at different extracellular potassium and pacing frequencies. , 1996, Journal of cardiovascular pharmacology.

[5]  Bertram Pitt,et al.  Effect of d-sotalol on mortality in patients with left ventricular dysfunction after recent and remote myocardial infarction , 1996, The Lancet.

[6]  S. Ogawa,et al.  Different responses of epicardium and endocardium to KATP channel modulators during regional ischemia. , 1996, The American journal of physiology.

[7]  W. Shimizu,et al.  Reverse use dependence of human ventricular repolarization by chronic oral sotalol in monophasic action potential recordings. , 1996, The American journal of cardiology.

[8]  S Nattel,et al.  Evidence for two components of delayed rectifier K+ current in human ventricular myocytes. , 1996, Circulation research.

[9]  A. Schömig,et al.  Different effects of β-adrenergic stimulation on the prolongation of action potential by Dofetilide and Ambasilide , 1996 .

[10]  D. Roden,et al.  Extracellular potassium modulation of drug block of IKr. Implications for torsade de pointes and reverse use-dependence. , 1996, Circulation.

[11]  J Weissenburger,et al.  Mexiletine antagonizes effects of sotalol on QT interval duration and its proarrhythmic effects in a canine model of torsade de pointes. , 1995, Journal of the American College of Cardiology.

[12]  B. Fermini,et al.  Use‐Dependent Effects of the Class III Antiarrhythmic Agent NE‐10064 (Azimilide) on Cardiac Repolarization: Block of Delayed Rectifier Potassium and L‐Type Calcium Currents , 1995, Journal of cardiovascular pharmacology.

[13]  S. Priori,et al.  Sympathetic activation, ventricular repolarization and Ikr blockade: implications for the antifibrillatory efficacy of potassium channel blocking agents. , 1995, Journal of the American College of Cardiology.

[14]  A. Camm,et al.  Survival with oral d-sotalol in patients with left ventricular dysfunction after myocardial infarction: rationale, design, and methods (the SWORD trial). , 1995, The American journal of cardiology.

[15]  A. Camm,et al.  901–41 Preliminary Mortality Results from the Survival with Oral D-Sotalol (SWORD) Trial , 1995 .

[16]  H. Wellens,et al.  Reproducible induction of early afterdepolarizations and torsade de pointes arrhythmias by d-sotalol and pacing in dogs with chronic atrioventricular block. , 1995, Circulation.

[17]  J. Maylie,et al.  Beta-adrenergic blocking property of dl-sotalol maintains class III efficacy in guinea pig ventricular muscle after isoproterenol. , 1995, Circulation.

[18]  A. Dart,et al.  Sympatholytic action of intravenous amiodarone in the rat heart. , 1995, Circulation.

[19]  C. Schmitt,et al.  Differential effects of D-sotalol on endocardial and epicardial action potentials of human ventricular myocardium in dilated cardiomyopathy. , 1994, Journal of cardiovascular pharmacology.

[20]  P. Sager,et al.  Frequency-Dependent Electrophysiologic Actions of Amiodarone and Sematilide in Humans , 2005 .

[21]  M. Franz,et al.  Prolongation of monophasic action potential duration and the refractory period in the human heart by tedisamil, a new potassium-blocking agent. , 1994, European heart journal.

[22]  S. Nattel,et al.  Class III antiarrhythmic drug action in experimental atrial fibrillation. Differences in reverse use dependence and effectiveness between d-sotalol and the new antiarrhythmic drug ambasilide. , 1994, Circulation.

[23]  J. Lynch,et al.  Comparative effects of increased extracellular potassium and pacing frequency on the class III activities of methanesulfonanilide IKr blockers dofetilide, D-sotalol, E-4031, and MK-499. , 1994, Journal of cardiovascular pharmacology.

[24]  U. Ravens,et al.  Effects of E-4031, almokalant and tedisamil on postrest action potential duration of human papillary muscles. , 1994, The Journal of pharmacology and experimental therapeutics.

[25]  P. Sager,et al.  Frequency-dependent electrophysiologic effects of amiodarone in humans. , 1993, Circulation.

[26]  P. Levesque,et al.  Anion and cation modulation of the guinea-pig ventricular action potential during β-adrenoceptor stimulation , 1993, Pflügers Archiv.

[27]  S. Cobbe,et al.  Effects of the class III antiarrhythmic drug dofetilide on ventricular monophasic action potential duration and QT interval dispersion in stable angina pectoris. , 1992, The American journal of cardiology.

[28]  H. Huikuri,et al.  Frequency Dependent Effects of d‐Sotalol and Amiodarone on the Action Potential Duration of the Human Right Ventricle , 1992, Pacing and clinical electrophysiology : PACE.

[29]  B. Singh,et al.  Effect of ambasilide, a new class III agent, on plateau currents in isolated guinea pig ventricular myocytes: block of delayed outward potassium current. , 1992, The Journal of pharmacology and experimental therapeutics.

[30]  E. Carmeliet Voltage- and time-dependent block of the delayed K+ current in cardiac myocytes by dofetilide. , 1992, The Journal of pharmacology and experimental therapeutics.

[31]  J. Brachmann,et al.  Differential Effects of Quinidine on Transmembrane Action Potentials of Normal and Infarcted Canine Purkinje Fibers , 1992, Journal of cardiovascular pharmacology.

[32]  J. Brachmann,et al.  Sotalol Exhibits Reverse Use‐Dependent Action on Monophasic Action Potentials in Normal but Not in Infarcted Canine Ventricular Myocardium , 1992, Journal of cardiovascular pharmacology.

[33]  G. Gintant,et al.  Heterogeneity within the ventricular wall. Electrophysiology and pharmacology of epicardial, endocardial, and M cells. , 1991, Circulation research.

[34]  J. Brachmann,et al.  Reverse use-dependent effects of sotalol demonstrated by recording monophasic action potentials of the right ventricle. , 1991, The American journal of cardiology.

[35]  C. Antzelevitch,et al.  Sodium channel block produces opposite electrophysiological effects in canine ventricular epicardium and endocardium. , 1991, Circulation research.

[36]  E. Platia,et al.  Monophasic action potential recordings: evaluation of antiarrhythmic drugs. , 1991, Progress in cardiovascular diseases.

[37]  M R Franz,et al.  In vivo electrophysiological detection of myocardial ischemia through monophasic action potential recording. , 1991, Progress in cardiovascular diseases.

[38]  M R Franz,et al.  Method and theory of monophasic action potential recording. , 1991, Progress in cardiovascular diseases.

[39]  A. Kadish,et al.  Magnitude and time course of beta-adrenergic antagonism during oral amiodarone therapy. , 1990, Journal of the American College of Cardiology.

[40]  M. Sanguinetti,et al.  Two components of cardiac delayed rectifier K+ current. Differential sensitivity to block by class III antiarrhythmic agents , 1990, The Journal of general physiology.

[41]  D. Snyders,et al.  Class III antiarrhythmic agents have a lot of potential but a long way to go. Reduced effectiveness and dangers of reverse use dependence. , 1990, Circulation.

[42]  P. Tchou,et al.  Isoproterenol reversal of antiarrhythmic effects in patients with inducible sustained ventricular tachyarrhythmias. , 1989, Journal of the American College of Cardiology.

[43]  A. Kadish,et al.  Epinephrine-induced reversal of verapamil's electrophysiologic and therapeutic effects in patients with paroxysmal supraventricular tachycardia. , 1989, Circulation.

[44]  W Craelius,et al.  QTU Prolongation and Polymorphic Ventricular Tachyarrhythmias Due to Bradycardia‐Dependent Early: Afterdepolarizations Afterdepolarizations and Ventricular Arrhythmias , 1988, Circulation research.

[45]  H. Karagueuzian,et al.  Relation of monophasic action potential recorded with contact electrode to underlying transmembrane action potential properties in isolated cardiac tissues: a systematic microelectrode validation study. , 1988, Cardiovascular research.

[46]  B. Surawicz,et al.  Effect of Antiarrhythmic Drugs on the Cycle Length-Dependent Action Potential Duration in Dog Purkinje and Ventricular Muscle Fibers , 1986, Journal of cardiovascular pharmacology.

[47]  P. Taggart,et al.  d-Sotalol: a new potent class III anti-arrhythmic agent. , 1985, Clinical science.

[48]  S. Olsson,et al.  Estimation of ventricular repolarization in man by monophasic action potential recording technique. , 1985, European heart journal.

[49]  R. Winkle,et al.  Facilitation of ventricular tachyarrhythmia induction by isoproterenol. , 1984, The American journal of cardiology.

[50]  M R Franz,et al.  Long-term recording of monophasic action potentials from human endocardium. , 1983, The American journal of cardiology.

[51]  J. Bigger,et al.  Electrophysiological and Beta‐Receptor Blocking Effects of MJ 1999 on Dog and Rabbit Cardiac Tissue , 1970, Circulation research.

[52]  P. Dorian,et al.  Electrophysiologic mechanisms of antiarrhythmic efficacy of a sotalol and class Ia drug combination: elimination of reverse use dependence. , 1997, Journal of the American College of Cardiology.

[53]  J. Stark How to choose a cardiac surgeon , 1996 .

[54]  S. Olsson,et al.  The dispersion of repolarization in patients with ventricular tachycardia. A study using simultaneous monophasic action potential recordings from two sites in the right ventricle. , 1995, European heart journal.

[55]  M. Sanguinetti,et al.  Rate-dependent prolongation of cardiac action potentials by a methanesulfonanilide class III antiarrhythmic agent. Specific block of rapidly activating delayed rectifier K+ current by dofetilide. , 1993, Circulation research.

[56]  M. Sanguinetti,et al.  Isoproterenol antagonizes prolongation of refractory period by the class III antiarrhythmic agent E-4031 in guinea pig myocytes. Mechanism of action. , 1991, Circulation research.

[57]  E. Lakatta,et al.  In vitro validation of a new cardiac catheter technique for recording monophasic action potentials. , 1986, European heart journal.